Result of FASTA (omim) for pF1KB9959
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9959, 538 aa
  1>>>pF1KB9959 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9256+/-0.0003; mu= 7.9193+/- 0.019
 mean_var=166.6388+/-32.917, 0's: 0 Z-trim(122.1): 140  B-trim: 77 in 1/60
 Lambda= 0.099354
 statistics sampled from 39485 (39645) to 39485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.465), width:  16
 Scan time: 10.100

The best scores are:                                      opt bits E(85289)
NP_001036189 (OMIM: 600798) nectin-2 isoform delta ( 538) 3592 526.7 7.1e-149
NP_002847 (OMIM: 600798) nectin-2 isoform alpha pr ( 479) 2373 351.9 2.6e-96
XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 is ( 369) 2324 344.8 2.7e-94
NP_001129242 (OMIM: 173850) poliovirus receptor is ( 392) 1006 155.9 2.1e-37
NP_006496 (OMIM: 173850) poliovirus receptor isofo ( 417) 1006 155.9 2.2e-37
NP_001129240 (OMIM: 173850) poliovirus receptor is ( 372)  998 154.7 4.5e-37
NP_001129241 (OMIM: 173850) poliovirus receptor is ( 364)  993 154.0 7.2e-37
NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 ( 458)  609 99.0 3.2e-20
XP_016861615 (OMIM: 607147) PREDICTED: nectin-3 is ( 510)  579 94.8 6.9e-19
NP_001230217 (OMIM: 607147) nectin-3 isoform 3 [Ho ( 487)  578 94.6 7.3e-19
XP_016861612 (OMIM: 607147) PREDICTED: nectin-3 is ( 541)  578 94.7   8e-19
NP_002846 (OMIM: 225060,600644) nectin-1 isoform 1 ( 517)  569 93.3 1.9e-18
NP_976031 (OMIM: 225060,600644) nectin-1 isoform 3 ( 352)  530 87.6 6.7e-17
NP_056295 (OMIM: 607147) nectin-3 isoform 1 precur ( 549)  483 81.0   1e-14
XP_016861614 (OMIM: 607147) PREDICTED: nectin-3 is ( 526)  482 80.9 1.1e-14
XP_016861613 (OMIM: 607147) PREDICTED: nectin-3 is ( 534)  482 80.9 1.1e-14
XP_011510965 (OMIM: 607147) PREDICTED: nectin-3 is ( 580)  482 80.9 1.2e-14
NP_001230215 (OMIM: 607147) nectin-3 isoform 2 pre ( 366)  468 78.8 3.3e-14
NP_112178 (OMIM: 609607,613573) nectin-4 precursor ( 510)  401 69.3 3.3e-11
XP_011508323 (OMIM: 609607,613573) PREDICTED: nect ( 511)  397 68.7 4.9e-11
XP_011508325 (OMIM: 609607,613573) PREDICTED: nect ( 460)  395 68.4 5.5e-11
XP_005245565 (OMIM: 609607,613573) PREDICTED: nect ( 485)  394 68.2 6.4e-11
XP_011508324 (OMIM: 609607,613573) PREDICTED: nect ( 486)  390 67.7 9.5e-11
XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395)  346 61.3 6.4e-09
XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397)  346 61.3 6.4e-09
NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404)  346 61.3 6.5e-09
XP_016861616 (OMIM: 607147) PREDICTED: nectin-3 is ( 337)  337 60.0 1.4e-08
NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435)  329 58.9 3.7e-08
XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435)  329 58.9 3.7e-08
NP_694854 (OMIM: 609938) cell adhesion molecule 2  ( 437)  329 58.9 3.7e-08
XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449)  329 58.9 3.8e-08
NP_001091987 (OMIM: 605686) cell adhesion molecule ( 414)  316 57.0 1.3e-07
XP_016872947 (OMIM: 605686) PREDICTED: cell adhesi ( 402)  305 55.4 3.8e-07
NP_055148 (OMIM: 605686) cell adhesion molecule 1  ( 442)  305 55.5 4.1e-07
NP_001287973 (OMIM: 605686) cell adhesion molecule ( 453)  305 55.5 4.2e-07
NP_001287972 (OMIM: 605686) cell adhesion molecule ( 471)  305 55.5 4.3e-07
XP_016872946 (OMIM: 605686) PREDICTED: cell adhesi ( 477)  305 55.5 4.3e-07
NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398)  302 55.0 5.1e-07
NP_067012 (OMIM: 609743) cell adhesion molecule 3  ( 432)  302 55.0 5.4e-07
XP_005271551 (OMIM: 605686) PREDICTED: cell adhesi ( 425)  301 54.9 5.9e-07
NP_001287974 (OMIM: 605686) cell adhesion molecule ( 443)  301 54.9 6.1e-07
NP_001243434 (OMIM: 609938) cell adhesion molecule ( 287)  284 52.3 2.3e-06
NP_001243433 (OMIM: 609938) cell adhesion molecule ( 287)  284 52.3 2.3e-06
NP_001243432 (OMIM: 609938) cell adhesion molecule ( 327)  267 49.9 1.4e-05
NP_001243431 (OMIM: 609938) cell adhesion molecule ( 327)  267 49.9 1.4e-05
XP_016872950 (OMIM: 605686) PREDICTED: cell adhesi ( 267)  253 47.9 4.8e-05
XP_016872949 (OMIM: 605686) PREDICTED: cell adhesi ( 295)  242 46.3 0.00016
XP_016872948 (OMIM: 605686) PREDICTED: cell adhesi ( 324)  242 46.3 0.00017
XP_011524624 (OMIM: 114890) PREDICTED: carcinoembr ( 524)  242 46.5 0.00024
XP_016881635 (OMIM: 114890) PREDICTED: carcinoembr ( 617)  242 46.5 0.00028


>>NP_001036189 (OMIM: 600798) nectin-2 isoform delta pre  (538 aa)
 initn: 3592 init1: 3592 opt: 3592  Z-score: 2793.8  bits: 526.7 E(85289): 7.1e-149
Smith-Waterman score: 3592; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)

               10        20        30        40        50        60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
              430       440       450       460       470       480

              490       500       510       520       530        
pF1KB9 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV
              490       500       510       520       530        

>>NP_002847 (OMIM: 600798) nectin-2 isoform alpha precur  (479 aa)
 initn: 2408 init1: 2340 opt: 2373  Z-score: 1850.2  bits: 351.9 E(85289): 2.6e-96
Smith-Waterman score: 2373; 90.4% identity (95.5% similar) in 397 aa overlap (1-394:1-397)

               10        20        30        40        50        60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA--GAGA-
       :::::::::::::::::::::::::::::::::::::::::::::::::: ..   .:  
NP_002 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB9 TGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEA
       . : .:: . ...  : .. .... : .:....  ::                       
NP_002 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDP
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KB9 QEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSP
                                                                   
NP_002 VFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV 
              430       440       450       460       470          

>>XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 isofor  (369 aa)
 initn: 2319 init1: 2319 opt: 2324  Z-score: 1813.9  bits: 344.8 E(85289): 2.7e-94
Smith-Waterman score: 2324; 96.4% identity (97.5% similar) in 362 aa overlap (1-362:1-362)

               10        20        30        40        50        60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
       :::::::::::::::::::::::::::::::::::::::::::::::   .   .   :.
XP_011 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRALEDDMESQLDGS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
       .:                                                          
XP_011 LISRRAVYV                                                   
                                                                   

>>NP_001129242 (OMIM: 173850) poliovirus receptor isofor  (392 aa)
 initn: 1128 init1: 964 opt: 1006  Z-score: 792.5  bits: 155.9 E(85289): 2.1e-37
Smith-Waterman score: 1133; 50.0% identity (72.8% similar) in 368 aa overlap (19-379:9-363)

               10        20             30        40        50     
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
                         :::::. ::       :. :: ::.  .: : :: .: :::.
NP_001           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
                         10        20        30        40        50

           60        70        80        90       100       110    
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
       : .: .   ..: .:: :    ..   .:.::  .:::.      :.:: ::.:. .   
NP_001 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
               60        70           80            90       100   

          120       130       140       150       160       170    
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
          :::..:.: . :: ::::::::: :.:::.::     ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
                 110       120       130       140       150       

          180       190       200       210       220       230    
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
        .:. .: :.:  :::::.:.: :.:    . .:: : :.::::::: . ::::...:: 
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
       160       170       180       190       200       210       

          240       250       260       270       280       290    
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
       .:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
       220       230       240       250       260       270       

          300       310       320       330       340       350    
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
       .:::: : .:  :::::.::.:. ::. .:::..:.::::.:  .:: .. :.: : .  
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
       280       290       300       310       320       330       

           360       370       380       390       400       410   
pF1KB9 AGAT-GGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKA
       .: . ..::  ... ..   . . ::                                  
NP_001 SGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSEHHQSCRN     
       340       350       360       370       380       390       

>>NP_006496 (OMIM: 173850) poliovirus receptor isoform a  (417 aa)
 initn: 1128 init1: 964 opt: 1006  Z-score: 792.1  bits: 155.9 E(85289): 2.2e-37
Smith-Waterman score: 1133; 50.0% identity (72.8% similar) in 368 aa overlap (19-379:9-363)

               10        20             30        40        50     
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
                         :::::. ::       :. :: ::.  .: : :: .: :::.
NP_006           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
                         10        20        30        40        50

           60        70        80        90       100       110    
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
       : .: .   ..: .:: :    ..   .:.::  .:::.      :.:: ::.:. .   
NP_006 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
               60        70           80            90       100   

          120       130       140       150       160       170    
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
          :::..:.: . :: ::::::::: :.:::.::     ::::.:::.: ::.::: ..
NP_006 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
                 110       120       130       140       150       

          180       190       200       210       220       230    
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
        .:. .: :.:  :::::.:.: :.:    . .:: : :.::::::: . ::::...:: 
NP_006 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
       160       170       180       190       200       210       

          240       250       260       270       280       290    
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
       .:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_006 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
       220       230       240       250       260       270       

          300       310       320       330       340       350    
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
       .:::: : .:  :::::.::.:. ::. .:::..:.::::.:  .:: .. :.: : .  
NP_006 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
       280       290       300       310       320       330       

           360       370       380       390       400       410   
pF1KB9 AGAT-GGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKA
       .: . ..::  ... ..   . . ::                                  
NP_006 SGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVS
       340       350       360       370       380       390       

>>NP_001129240 (OMIM: 173850) poliovirus receptor isofor  (372 aa)
 initn: 1126 init1: 962 opt: 998  Z-score: 786.6  bits: 154.7 E(85289): 4.5e-37
Smith-Waterman score: 1125; 52.3% identity (74.1% similar) in 344 aa overlap (19-356:9-339)

               10        20             30        40        50     
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
                         :::::. ::       :. :: ::.  .: : :: .: :::.
NP_001           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
                         10        20        30        40        50

           60        70        80        90       100       110    
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
       : .: .   ..: .:: :    ..  ..:.::  .:::.      :.:: ::.:. .   
NP_001 LQVPNMEVTHVSQLTWAR---HGESGSMAVFHQTQGPSYSE----SKRLEFVAARLG---
               60           70        80            90       100   

          120       130       140       150       160       170    
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
          :::..:.: . :: ::::::::: :.:::.::     ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
                 110       120       130       140       150       

          180       190       200       210       220       230    
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
        .:. .: :.:  :::::.:.: :.:    . .:: : :.::::::: . ::::...:: 
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
       160       170       180       190       200       210       

          240       250       260       270       280       290    
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
       .:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
       220       230       240       250       260       270       

          300       310       320       330       340       350    
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
       .:::: : .:  :::::.::.:. ::. .:::..:.::::.:  .:: .. :.: : .  
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
       280       290       300       310       320       330       

          360       370       380       390       400       410    
pF1KB9 AGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAK
       .:                                                          
NP_001 SGTEHASASANGHVSYSAVSRENSSSQDPQTEGTR                         
       340       350       360       370                           

>>NP_001129241 (OMIM: 173850) poliovirus receptor isofor  (364 aa)
 initn: 1110 init1: 946 opt: 993  Z-score: 782.9  bits: 154.0 E(85289): 7.2e-37
Smith-Waterman score: 1120; 52.1% identity (74.5% similar) in 349 aa overlap (19-361:9-343)

               10        20             30        40        50     
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
                         :::::. ::       :. :: ::.  .: : :: .: :::.
NP_001           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
                         10        20        30        40        50

           60        70        80        90       100       110    
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
       : .: .   ..: .:: :    ..  ..:.::  .:::.      :.:: ::.:. .   
NP_001 LQVPNMEVTHVSQLTWAR---HGESGSMAVFHQTQGPSYSE----SKRLEFVAARLG---
               60           70        80            90       100   

          120       130       140       150       160       170    
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
          :::..:.: . :: ::::::::: :.:::.::     ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
                 110       120       130       140       150       

          180       190       200       210       220       230    
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
        .:. .: :.:  :::::.:.: :.:    . .:: : :.::::::: . ::::...:: 
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
       160       170       180       190       200       210       

          240       250       260       270       280       290    
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
       .:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
       220       230       240       250       260       270       

          300       310       320       330       340       350    
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
       .:::: : .:  :::::.::.:. ::. .:::..:.::::.:  .:: .. :. : . :.
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEH-AS
       280       290       300       310       320       330       

          360       370       380       390       400       410    
pF1KB9 AGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAK
       :.:.: .                                                     
NP_001 ASANGHVSYSAVSRENSSSQDPQTEGTR                                
        340       350       360                                    

>>NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 pre  (458 aa)
 initn: 676 init1: 213 opt: 609  Z-score: 484.0  bits: 99.0 E(85289): 3.2e-20
Smith-Waterman score: 753; 33.6% identity (59.6% similar) in 470 aa overlap (19-463:14-454)

               10        20          30        40        50        
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLL--LLETGAQDVRVQVLPEVRGQLGGTVELPCHLLP
                         : : : :  ..  :...  :::   . : .:  : : : .  
NP_976      MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFAN
                    10        20        30        40        50     

       60        70        80        90       100       110        
pF1KB9 PVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEA
       :.:.. :. ::::. .. ...:::: ..:.:: :  .:    ::. :.  .         
NP_976 PLPSVKITQVTWQK-STNGSKQNVAIYNPSMGVSVLAPY--RERVEFLRPS---------
          60         70        80        90         100            

      120       130       140       150       160       170        
pF1KB9 ELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF-----
        . :.:. :  : .:::: : ::::::: :. ...  : :.::: :  :. ....     
NP_976 -FTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKG
            110       120       130       140       150       160  

           180       190       200       210       220       230   
pF1KB9 SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG
       ..: . :: : : .:.::. .:: . :  ::.  .. .   ::::: ::. :::: .:  
NP_976 QDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNP-NGTVTVISRYRLVPSREAHQ
            170       180       190       200        210       220 

           240         250       260       270       280       290 
pF1KB9 VTVTCKVEH--ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEP
        ...: :..  . :.:     .::.:.: :::.: :.: :::: : :. :.: . .::  
NP_976 QSLACIVNYHMDRFKES----LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPA
             230           240       250       260       270       

             300       310        320       330       340          
pF1KB9 TGYDWSTTSGTFPTSAVAQGSQLVIHA-VDSLFNTTFVCTVTNAVGMGRAEQV-IFVRET
       : : :.: .:..: .. ::.  : ... ..  .  :..: .:: .:  :. :: . . : 
NP_976 TEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGT-RSGQVEVNITEK
       280       290       300       310       320        330      

     350        360        370       380       390       400       
pF1KB9 PNTA-GAGATGGIIGGIIAA-IIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYK
       :    : :... ...: .:. .: .:: .. .:  :::..    .::  :.    : : :
NP_976 PRPQRGLGSAARLLAGTVAVFLILVAVLTVFFLYNRQQKSPPETDGAGTDQ----PLSQK
        340       350       360       370       380           390  

        410         420       430               440       450      
pF1KB9 P-PTP--KAKLEAQEMPSQLFTLGASEHSP--------LKTPYFDAGASCTEQEMPRYHE
       : :.:  ...:  ...    .  : ....         :. ::.: :.:      : :: 
NP_976 PEPSPSRQSSLVPEDIQVVHLDPGRQQQQEEEDLQKLSLQPPYYDLGVS------PSYHP
            400       410       420       430       440            

         460       470       480       490       500       510     
pF1KB9 -LPTLEERSGPLHPGATSLGSPIPVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDA
        . : : :                                                    
NP_976 SVRTTEPRGECP                                                
        450                                                        

>>XP_016861615 (OMIM: 607147) PREDICTED: nectin-3 isofor  (510 aa)
 initn: 490 init1: 325 opt: 579  Z-score: 460.1  bits: 94.8 E(85289): 6.9e-19
Smith-Waterman score: 662; 30.2% identity (60.4% similar) in 437 aa overlap (13-439:33-440)

                                 10             20        30       
pF1KB9                   MARAAALLPSRSPPTP-----LLWPLLLLLLLETGAQDVRVQ
                                     ::::     ::.::::.  :  ::    . 
XP_016 RTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRL-CGALAGPII
             10        20        30        40        50         60 

        40        50        60        70        80        90       
pF1KB9 VLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPK
       : :.: .  : .: : :  :  : .  :. ..:..  . .. :.::. ::..: :  .  
XP_016 VEPHVTAVWGKNVSLKC--LIEV-NETITQISWEKIHGKSS-QTVAVHHPQYGFSVQGEY
              70          80         90        100       110       

       100       110       120       130       140       150       
pF1KB9 PGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR
        :  :. :           .  :.:::..::..   : :.: :. .::: :.... : . 
XP_016 QG--RVLF----------KNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVT
         120                 130       140       150       160     

       160         170       180       190       200       210     
pF1KB9 VIAKPKNQ--AEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAG
       :...:  .     ...  . . :..:.::.  :.: :.:.: ..:     :. ...    
XP_016 VLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLG--EMESTTTSFPNE
         170       180       190       200       210         220   

         220       230       240       250       260       270     
pF1KB9 TVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLG
       :.:. :.. : :.  : :  .:: :.: ..:.       :...: ::::..::: ::..:
XP_016 TATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVG
           230       240       250       260       270       280   

         280       290       300       310        320       330    
pF1KB9 RTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQL-VIHAVDSLFNTTFVCTVTNA
       :  ..:.:.. .:: :    ::  .: .: . .:. . :  .: .   .. ...: :::.
XP_016 RKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNS
           290       300       310       320       330       340   

          340       350         360       370       380       390  
pF1KB9 VGMGRAEQVIFVRETP--NTAGAGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQ
       .:.   ..::.. ..:  .:.. ...:..::...: .:  :. .: .:  :..:      
XP_016 LGQRSDQKVIYISDVPFKQTSSIAVAGAVIGAVLALFII-AIFVTVLLTPRKKRPSYL--
           350       360       370       380        390       400  

            400       410       420       430       440       450  
pF1KB9 GAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMP
           :. .. ::..::: :  . ..  .:..   :   :: ::.: .             
XP_016 ----DKVIDLPPTHKPP-PLYEERSPPLPQK--DLFQPEHLPLQTQFKEREVGNLQHSNG
                  410        420         430       440       450   

            460       470       480       490       500       510  
pF1KB9 RYHELPTLEERSGPLHPGATSLGSPIPVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPI
                                                                   
XP_016 LNSRSFDYEDENPVGEDGIQQMYPLYNQMCYQDRSPGKHHQNNDPKRVYIDPREHYV   
           460       470       480       490       500       510   

>>NP_001230217 (OMIM: 607147) nectin-3 isoform 3 [Homo s  (487 aa)
 initn: 397 init1: 325 opt: 578  Z-score: 459.6  bits: 94.6 E(85289): 7.3e-19
Smith-Waterman score: 622; 29.3% identity (61.4% similar) in 409 aa overlap (36-439:37-417)

          10        20        30        40        50        60     
pF1KB9 ALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYI
                                     . : :.: .  : .: : :  :  : .  :
NP_001 WCFVRRTPGLLRGPLLPRSFSGNPRALAGPIIVEPHVTAVWGKNVSLKC--LIEV-NETI
         10        20        30        40        50           60   

          70        80        90       100       110       120     
pF1KB9 SLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATL
       . ..:..  . .. :.::. ::..: :  .   :  :. :   :. .       :.:::.
NP_001 TQISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLF---KNYS-------LNDATI
            70         80        90         100                 110

         130       140       150       160         170       180   
pF1KB9 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQ--AEAQKVTFSQDPTTVALC
       .::..   : :.: :. .::: :.... : . :...:  .     ...  . . :..:.:
NP_001 TLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAIC
              120       130       140       150       160       170

           190       200       210       220       230       240   
pF1KB9 ISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHE
       :.  :.: :.:.: ..:     :. ...    :.:. :.. : :.  : :  .:: :.: 
NP_001 IAATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHP
              180         190       200       210       220        

           250       260       270       280       290       300   
pF1KB9 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTF
       ..:.       :...: ::::..::: ::..::  ..:.:.. .:: :    ::  .: .
NP_001 ALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQW
      230       240       250       260       270       280        

           310        320       330       340       350         360
pF1KB9 PTSAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP--NTAGAGATGG
       : . .:. . :  .: .   .. ...: :::..:.   ..::.. ..:  .:.. ...:.
NP_001 PDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDVPFKQTSSIAVAGA
      290       300       310       320       330       340        

              370       380       390       400       410       420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
       .::...: .:  :. .: .:  :..:          :. .. ::..::: :  . ..  .
NP_001 VIGAVLALFII-AIFVTVLLTPRKKRPSYL------DKVIDLPPTHKPP-PLYEERSPPL
      350        360       370             380       390        400

              430       440       450       460       470       480
pF1KB9 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
       :..   :   :: ::.: .                                         
NP_001 PQK--DLFQPEHLPLQTQFKEREVGNLQHSNGLNSRSFDYEDENPVGEDGIQQMYPLYNQ
                410       420       430       440       450        




538 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:19:47 2016 done: Fri Nov  4 09:19:49 2016
 Total Scan time: 10.100 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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