Result of FASTA (omim) for pF1KB6965
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6965, 173 aa
  1>>>pF1KB6965 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.4555+/-0.000432; mu= 17.1857+/- 0.026
 mean_var=68.5914+/-14.540, 0's: 0 Z-trim(110.3): 48  B-trim: 0 in 0/53
 Lambda= 0.154860
 statistics sampled from 18559 (18599) to 18559 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.218), width:  16
 Scan time:  3.990

The best scores are:                                      opt bits E(85289)
NP_001155220 (OMIM: 154045,615277) lens fiber memb ( 173) 1205 278.1 4.8e-75
NP_085915 (OMIM: 154045,615277) lens fiber membran ( 215)  782 183.7 1.6e-46
NP_001414 (OMIM: 602333) epithelial membrane prote ( 157)  199 53.3   2e-07
NP_005592 (OMIM: 606008) protein NKG7 [Homo sapien ( 165)  168 46.4 2.5e-05
XP_006720927 (OMIM: 602334,615861) PREDICTED: epit ( 167)  156 43.8 0.00016
NP_001415 (OMIM: 602334,615861) epithelial membran ( 167)  156 43.8 0.00016
NP_001268384 (OMIM: 118220,118300,139393,145900,16 ( 160)  146 41.5 0.00075
NP_696996 (OMIM: 118220,118300,139393,145900,16250 ( 160)  146 41.5 0.00075
NP_001268385 (OMIM: 118220,118300,139393,145900,16 ( 160)  146 41.5 0.00075
NP_000295 (OMIM: 118220,118300,139393,145900,16250 ( 160)  146 41.5 0.00075
NP_696997 (OMIM: 118220,118300,139393,145900,16250 ( 160)  146 41.5 0.00075
NP_001002026 (OMIM: 609210) claudin-18 isoform 2 [ ( 261)  136 39.5   0.005


>>NP_001155220 (OMIM: 154045,615277) lens fiber membrane  (173 aa)
 initn: 1205 init1: 1205 opt: 1205  Z-score: 1468.4  bits: 278.1 E(85289): 4.8e-75
Smith-Waterman score: 1205; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)

               10        20        30        40        50        60
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 WNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYT
               70        80        90       100       110       120

              130       140       150       160       170   
pF1KB6 GVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
              130       140       150       160       170   

>>NP_085915 (OMIM: 154045,615277) lens fiber membrane in  (215 aa)
 initn: 1191 init1: 782 opt: 782  Z-score: 956.4  bits: 183.7 E(85289): 1.6e-46
Smith-Waterman score: 1039; 79.5% identity (79.5% similar) in 205 aa overlap (11-173:11-215)

               10        20        30        40        50          
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSI--
                 ::::::::::::::::::::::::::::::::::::::::::::::::  
NP_085 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIGE
               10        20        30        40        50        60

                                               60        70        
pF1KB6 ----------------------------------------AYWNATRAFMILSALCAISG
                                               ::::::::::::::::::::
NP_085 PPGQGPGRAWGKSRADLGAQGHLYSRWRTLRLKEGKGATQAYWNATRAFMILSALCAISG
               70        80        90       100       110       120

       80        90       100       110       120       130        
pF1KB6 IIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 IIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSW
              130       140       150       160       170       180

      140       150       160       170   
pF1KB6 SYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
       :::::::::::::::::::::::::::::::::::
NP_085 SYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
              190       200       210     

>>NP_001414 (OMIM: 602333) epithelial membrane protein 1  (157 aa)
 initn: 141 init1:  79 opt: 199  Z-score: 254.2  bits: 53.3 E(85289): 2e-07
Smith-Waterman score: 199; 27.7% identity (62.9% similar) in 159 aa overlap (8-158:7-152)

               10         20        30         40        50        
pF1KB6 MYSFMGGGLFCAWVGT-ILLVVAMATDHWMQYRLSGSF-AHQGLWRYCLGNKCYLQTDSI
              :.: . ..: :.: :.  .. :.   .:..  :  :::. : . .:   .::.
NP_001  MLVLLAGIFVVHIATVIMLFVSTIANVWL---VSNTVDASVGLWKNCTNISC---SDSL
                10        20           30        40           50   

       60             70         80        90       100       110  
pF1KB6 AYWN-----ATRAFMILSAL-CAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFV
       .: .     ...:::::: . :.:. ... .. :    :. . .: : .:   .   : .
NP_001 SYASEDALKTVQAFMILSIIFCVIALLVFVFQLF----TMEKGNRFFLSGATTLVCWLCI
            60        70        80            90       100         

            120       130       140       150       160       170  
pF1KB6 VLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTP
       .....:::.    . .:   ... ..::::::.   ..:. :..:.              
NP_001 LVGVSIYTS---HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK         
     110          120       130       140       150                

        
pF1KB6 R

>>NP_005592 (OMIM: 606008) protein NKG7 [Homo sapiens]    (165 aa)
 initn: 188 init1:  86 opt: 168  Z-score: 216.5  bits: 46.4 E(85289): 2.5e-05
Smith-Waterman score: 173; 25.5% identity (59.6% similar) in 161 aa overlap (3-161:8-154)

                    10        20        30        40        50     
pF1KB6      MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQT
              ...::.:     : .. ..:..:: :..       ::.:::    :       
NP_005 MELCRSLALLGGSL-----GLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHG-------
               10             20        30        40               

           60        70        80        90        100       110   
pF1KB6 DSIA-YWNATRAFMILSALCAISGIIMGIMAFAHQPT-FSRISRPFSAGIMFFSSTLFVV
       : :. : ..:..: :...: :.  . .......  :. :     :. .    :.... .:
NP_005 DIISGYIHVTQTFSIMAVLWAL--VSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMV
       50        60        70          80        90       100      

           120       130       140       150       160       170   
pF1KB6 LALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
       .:.:.::.   .   .   .  ::::. ::::.... . .: . . :.            
NP_005 VAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL 
        110       120       130       140       150       160      

>>XP_006720927 (OMIM: 602334,615861) PREDICTED: epitheli  (167 aa)
 initn: 118 init1:  78 opt: 156  Z-score: 202.0  bits: 43.8 E(85289): 0.00016
Smith-Waterman score: 156; 28.9% identity (57.9% similar) in 152 aa overlap (18-158:18-161)

               10        20        30        40         50         
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGN-KCYLQTDSIA
                        :: .: . . :      :.     .:: : .: .: . .::. 
XP_006 MLVLLAFIIAFHITSAALLFIATVDNAWW----VGDEFFADVWRICTNNTNCTVINDSFQ
               10        20            30        40        50      

      60           70         80        90       100       110     
pF1KB6 YWN---ATRAFMILSA-LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
        ..   :..: ::::. :: :. .:. .. :     ...  :   ..:. . : : :..:
XP_006 EYSTLQAVQATMILSTILCCIAFFIFVLQLF----RLKQGERFVLTSIIQLMSCLCVMIA
         60        70        80            90       100       110  

         120         130           140       150       160         
pF1KB6 LAIYTGVTVSFLGR--RFG----DWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRL
        .:::    ..  .  .:     .  ...::::.:::   ::..:..:.           
XP_006 ASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK     
            120       130       140       150       160            

     170   
pF1KB6 STPR

>>NP_001415 (OMIM: 602334,615861) epithelial membrane pr  (167 aa)
 initn: 118 init1:  78 opt: 156  Z-score: 202.0  bits: 43.8 E(85289): 0.00016
Smith-Waterman score: 156; 28.9% identity (57.9% similar) in 152 aa overlap (18-158:18-161)

               10        20        30        40         50         
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGN-KCYLQTDSIA
                        :: .: . . :      :.     .:: : .: .: . .::. 
NP_001 MLVLLAFIIAFHITSAALLFIATVDNAWW----VGDEFFADVWRICTNNTNCTVINDSFQ
               10        20            30        40        50      

      60           70         80        90       100       110     
pF1KB6 YWN---ATRAFMILSA-LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
        ..   :..: ::::. :: :. .:. .. :     ...  :   ..:. . : : :..:
NP_001 EYSTLQAVQATMILSTILCCIAFFIFVLQLF----RLKQGERFVLTSIIQLMSCLCVMIA
         60        70        80            90       100       110  

         120         130           140       150       160         
pF1KB6 LAIYTGVTVSFLGR--RFG----DWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRL
        .:::    ..  .  .:     .  ...::::.:::   ::..:..:.           
NP_001 ASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK     
            120       130       140       150       160            

     170   
pF1KB6 STPR

>>NP_001268384 (OMIM: 118220,118300,139393,145900,162500  (160 aa)
 initn: 107 init1:  58 opt: 146  Z-score: 190.1  bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)

               10        20        30        40            50      
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
                       .:: :.  ...:.     :.     ::. :     ::  .  ..
NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
               10        20            30        40        50      

         60         70        80        90       100       110     
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
       :   : ....: :::: . .: ..   .. : .  :... .: . .::. . . : :. :
NP_001 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
         60        70        80           90       100       110   

         120       130       140       150       160       170   
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
        ::::     .  .  .:. ....:::.:::  .....:..:.               
NP_001 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE         
           120         130       140       150       160         

>>NP_696996 (OMIM: 118220,118300,139393,145900,162500,18  (160 aa)
 initn: 107 init1:  58 opt: 146  Z-score: 190.1  bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)

               10        20        30        40            50      
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
                       .:: :.  ...:.     :.     ::. :     ::  .  ..
NP_696 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
               10        20            30        40        50      

         60         70        80        90       100       110     
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
       :   : ....: :::: . .: ..   .. : .  :... .: . .::. . . : :. :
NP_696 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
         60        70        80           90       100       110   

         120       130       140       150       160       170   
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
        ::::     .  .  .:. ....:::.:::  .....:..:.               
NP_696 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE         
           120         130       140       150       160         

>>NP_001268385 (OMIM: 118220,118300,139393,145900,162500  (160 aa)
 initn: 107 init1:  58 opt: 146  Z-score: 190.1  bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)

               10        20        30        40            50      
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
                       .:: :.  ...:.     :.     ::. :     ::  .  ..
NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
               10        20            30        40        50      

         60         70        80        90       100       110     
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
       :   : ....: :::: . .: ..   .. : .  :... .: . .::. . . : :. :
NP_001 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
         60        70        80           90       100       110   

         120       130       140       150       160       170   
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
        ::::     .  .  .:. ....:::.:::  .....:..:.               
NP_001 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE         
           120         130       140       150       160         

>>NP_000295 (OMIM: 118220,118300,139393,145900,162500,18  (160 aa)
 initn: 107 init1:  58 opt: 146  Z-score: 190.1  bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)

               10        20        30        40            50      
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
                       .:: :.  ...:.     :.     ::. :     ::  .  ..
NP_000 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
               10        20            30        40        50      

         60         70        80        90       100       110     
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
       :   : ....: :::: . .: ..   .. : .  :... .: . .::. . . : :. :
NP_000 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
         60        70        80           90       100       110   

         120       130       140       150       160       170   
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
        ::::     .  .  .:. ....:::.:::  .....:..:.               
NP_000 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE         
           120         130       140       150       160         




173 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:12:45 2016 done: Fri Nov  4 11:12:45 2016
 Total Scan time:  3.990 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com