Result of FASTA (omim) for pF1KB8500
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8500, 862 aa
  1>>>pF1KB8500 862 - 862 aa - 862 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3393+/-0.000477; mu= 5.5488+/- 0.030
 mean_var=143.8366+/-28.676, 0's: 0 Z-trim(113.2): 58  B-trim: 86 in 1/52
 Lambda= 0.106940
 statistics sampled from 22435 (22493) to 22435 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.264), width:  16
 Scan time: 13.230

The best scores are:                                      opt bits E(85289)
NP_000526 (OMIM: 276300,600259,614337) mismatch re ( 862) 5683 889.5       0
NP_001308943 (OMIM: 276300,600259,614337) mismatch ( 873) 4964 778.6       0
NP_001308944 (OMIM: 276300,600259,614337) mismatch ( 759) 4950 776.4       0
NP_001308936 (OMIM: 276300,600259,614337) mismatch ( 756) 4945 775.6       0
NP_001308937 (OMIM: 276300,600259,614337) mismatch ( 756) 4945 775.6       0
NP_001308932 (OMIM: 276300,600259,614337) mismatch ( 727) 4832 758.2 3.1e-218
NP_001308933 (OMIM: 276300,600259,614337) mismatch ( 727) 4832 758.2 3.1e-218
NP_001308934 (OMIM: 276300,600259,614337) mismatch ( 727) 4832 758.2 3.1e-218
NP_001308942 (OMIM: 276300,600259,614337) mismatch ( 671) 4164 655.1 3.1e-187
NP_001308938 (OMIM: 276300,600259,614337) mismatch ( 738) 4113 647.2 7.9e-185
XP_006715807 (OMIM: 276300,600259,614337) PREDICTE ( 551) 3617 570.7 6.6e-162
NP_001308941 (OMIM: 276300,600259,614337) mismatch ( 551) 3617 570.7 6.6e-162
XP_016867831 (OMIM: 276300,600259,614337) PREDICTE ( 551) 3617 570.7 6.6e-162
NP_001308940 (OMIM: 276300,600259,614337) mismatch ( 551) 3617 570.7 6.6e-162
NP_001308939 (OMIM: 276300,600259,614337) mismatch ( 675) 3170 501.7 4.5e-141
NP_001308935 (OMIM: 276300,600259,614337) mismatch ( 810) 3170 501.8 5.3e-141
NP_001307973 (OMIM: 120435,600258) PMS1 protein ho ( 731)  468 84.9 1.5e-15
NP_001121616 (OMIM: 120435,600258) PMS1 protein ho ( 770)  468 84.9 1.6e-15
XP_016859837 (OMIM: 120435,600258) PREDICTED: PMS1 ( 770)  468 84.9 1.6e-15
XP_016859833 (OMIM: 120435,600258) PREDICTED: PMS1 ( 893)  468 84.9 1.8e-15
NP_001121615 (OMIM: 120435,600258) PMS1 protein ho ( 893)  468 84.9 1.8e-15
NP_000525 (OMIM: 120435,600258) PMS1 protein homol ( 932)  468 84.9 1.9e-15
NP_001307974 (OMIM: 120435,600258) PMS1 protein ho ( 932)  468 84.9 1.9e-15
NP_001307976 (OMIM: 120435,600258) PMS1 protein ho ( 932)  468 84.9 1.9e-15
NP_001307977 (OMIM: 120435,600258) PMS1 protein ho ( 932)  468 84.9 1.9e-15
NP_001245200 (OMIM: 120436,158320,276300,609310) D ( 687)  449 81.9 1.1e-14
NP_000240 (OMIM: 120436,158320,276300,609310) DNA  ( 756)  449 82.0 1.2e-14
XP_005265218 (OMIM: 120436,158320,276300,609310) P ( 687)  446 81.5 1.5e-14
NP_001307978 (OMIM: 120435,600258) PMS1 protein ho ( 181)  386 72.0 2.8e-12
NP_001307980 (OMIM: 120435,600258) PMS1 protein ho ( 165)  385 71.8 2.9e-12
XP_011534950 (OMIM: 604395,608089,614385) PREDICTE (1157)  274 55.0 2.3e-06
XP_005267591 (OMIM: 604395,608089,614385) PREDICTE (1275)  274 55.0 2.5e-06
XP_005267590 (OMIM: 604395,608089,614385) PREDICTE (1394)  274 55.1 2.7e-06
XP_011534948 (OMIM: 604395,608089,614385) PREDICTE (1396)  274 55.1 2.7e-06
XP_005267589 (OMIM: 604395,608089,614385) PREDICTE (1418)  274 55.1 2.8e-06
XP_016876708 (OMIM: 604395,608089,614385) PREDICTE (1429)  274 55.1 2.8e-06
NP_055196 (OMIM: 604395,608089,614385) DNA mismatc (1429)  274 55.1 2.8e-06
XP_006720179 (OMIM: 604395,608089,614385) PREDICTE (1453)  274 55.1 2.8e-06
NP_001035197 (OMIM: 604395,608089,614385) DNA mism (1453)  274 55.1 2.8e-06
XP_016859838 (OMIM: 120435,600258) PREDICTED: PMS1 ( 717)  219 46.5 0.00054
XP_016859840 (OMIM: 120435,600258) PREDICTED: PMS1 ( 594)  204 44.1  0.0023
XP_006712659 (OMIM: 120435,600258) PREDICTED: PMS1 ( 747)  204 44.2  0.0028
NP_001276338 (OMIM: 120435,600258) PMS1 protein ho ( 756)  204 44.2  0.0028
XP_011509658 (OMIM: 120435,600258) PREDICTED: PMS1 ( 756)  204 44.2  0.0028
NP_001276337 (OMIM: 120435,600258) PMS1 protein ho ( 756)  204 44.2  0.0028


>>NP_000526 (OMIM: 276300,600259,614337) mismatch repair  (862 aa)
 initn: 5683 init1: 5683 opt: 5683  Z-score: 4747.3  bits: 889.5 E(85289):    0
Smith-Waterman score: 5683; 99.8% identity (99.9% similar) in 862 aa overlap (1-862:1-862)

               10        20        30        40        50        60
pF1KB8 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRSQKEAVSSSHG
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_000 REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB8 QDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHP
              790       800       810       820       830       840

              850       860  
pF1KB8 WNCPHGRPTMRHIANLGVISQN
       ::::::::::::::::::::::
NP_000 WNCPHGRPTMRHIANLGVISQN
              850       860  

>>NP_001308943 (OMIM: 276300,600259,614337) mismatch rep  (873 aa)
 initn: 5669 init1: 4964 opt: 4964  Z-score: 4147.7  bits: 778.6 E(85289):    0
Smith-Waterman score: 5651; 98.5% identity (98.6% similar) in 873 aa overlap (1-862:1-873)

               10        20        30        40        50        60
pF1KB8 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRSQKEAVSSSHG
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 ETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG
              670       680       690       700       710       720

              730       740       750                  760         
pF1KB8 QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEN-----------APVTERAKLIS
       ::::::::::::::::::::::::::::::::::::::           :::::::::::
NP_001 QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENVMDFSQNCILLAPVTERAKLIS
              730       740       750       760       770       780

     770       780       790       800       810       820         
pF1KB8 LPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKK
              790       800       810       820       830       840

     830       840       850       860  
pF1KB8 LITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       :::::::::::::::::::::::::::::::::
NP_001 LITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              850       860       870   

>>NP_001308944 (OMIM: 276300,600259,614337) mismatch rep  (759 aa)
 initn: 4944 init1: 4944 opt: 4950  Z-score: 4137.0  bits: 776.4 E(85289):    0
Smith-Waterman score: 4950; 98.4% identity (99.1% similar) in 758 aa overlap (108-862:2-759)

        80        90       100       110          120       130    
pF1KB8 ENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCAL---SDVTISTCHASAKVGTR
                                     : .:.. : .   :::::::::::::::::
NP_001                              MGLSLNTPCLVFSHSDVTISTCHASAKVGTR
                                            10        20        30 

          140       150       160       170       180       190    
pF1KB8 LMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCII
              40        50        60        70        80        90 

          200       210       220       230       240       250    
pF1KB8 SAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEE
             100       110       120       130       140       150 

          260       270       280       290       300       310    
pF1KB8 YGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYN
             160       170       180       190       200       210 

          320       330       340       350       360       370    
pF1KB8 RHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQ
             220       230       240       250       260       270 

          380       390       400       410       420       430    
pF1KB8 QPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKP
             280       290       300       310       320       330 

          440       450       460       470       480       490    
pF1KB8 HSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRSQKEAVSSSHGPSDPTDRAEVEKDS
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 HSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDS
             340       350       360       370       380       390 

          500       510       520       530       540       550    
pF1KB8 GHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPETDDSFSDVDCHSN
       ::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 GHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSN
             400       410       420       430       440       450 

          560       570       580       590       600       610    
pF1KB8 QEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKK
             460       470       480       490       500       510 

          620       630       640       650       660       670    
pF1KB8 VVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFA
             520       530       540       550       560       570 

          680       690       700       710       720       730    
pF1KB8 EMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAV
             580       590       600       610       620       630 

          740       750       760       770       780       790    
pF1KB8 NEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSP
             640       650       660       670       680       690 

          800       810       820       830       840       850    
pF1KB8 GVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIA
             700       710       720       730       740       750 

          860  
pF1KB8 NLGVISQN
       ::::::::
NP_001 NLGVISQN
               

>>NP_001308936 (OMIM: 276300,600259,614337) mismatch rep  (756 aa)
 initn: 4945 init1: 4945 opt: 4945  Z-score: 4132.9  bits: 775.6 E(85289):    0
Smith-Waterman score: 4945; 99.6% identity (99.9% similar) in 746 aa overlap (117-862:11-756)

         90       100       110       120       130       140      
pF1KB8 HHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQK
                                     :.::::::::::::::::::::::::::::
NP_001                     MWGRRRKLRRLNDVTISTCHASAKVGTRLMFDHNGKIIQK
                                   10        20        30        40

        150       160       170       180       190       200      
pF1KB8 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
               50        60        70        80        90       100

        210       220       230       240       250       260      
pF1KB8 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
              110       120       130       140       150       160

        270       280       290       300       310       320      
pF1KB8 FYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNIS
              170       180       190       200       210       220

        330       340       350       360       370       380      
pF1KB8 VDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIK
              230       240       250       260       270       280

        390       400       410       420       430       440      
pF1KB8 MHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSP
              290       300       310       320       330       340

        450       460       470       480       490       500      
pF1KB8 LGQKRGMLSSSTSGAISDKGVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGF
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 LGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGF
              350       360       370       380       390       400

        510       520       530       540       550       560      
pF1KB8 SIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLP
       ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_001 SIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLP
              410       420       430       440       450       460

        570       580       590       600       610       620      
pF1KB8 QPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLA
              470       480       490       500       510       520

        630       640       650       660       670       680      
pF1KB8 KRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGF
              530       540       550       560       570       580

        690       700       710       720       730       740      
pF1KB8 IITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIF
              590       600       610       620       630       640

        750       760       770       780       790       800      
pF1KB8 RKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQM
              650       660       670       680       690       700

        810       820       830       840       850       860  
pF1KB8 FASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              710       720       730       740       750      

>>NP_001308937 (OMIM: 276300,600259,614337) mismatch rep  (756 aa)
 initn: 4945 init1: 4945 opt: 4945  Z-score: 4132.9  bits: 775.6 E(85289):    0
Smith-Waterman score: 4945; 99.6% identity (99.9% similar) in 746 aa overlap (117-862:11-756)

         90       100       110       120       130       140      
pF1KB8 HHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQK
                                     :.::::::::::::::::::::::::::::
NP_001                     MWGRRRKLRRLNDVTISTCHASAKVGTRLMFDHNGKIIQK
                                   10        20        30        40

        150       160       170       180       190       200      
pF1KB8 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
               50        60        70        80        90       100

        210       220       230       240       250       260      
pF1KB8 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
              110       120       130       140       150       160

        270       280       290       300       310       320      
pF1KB8 FYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNIS
              170       180       190       200       210       220

        330       340       350       360       370       380      
pF1KB8 VDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIK
              230       240       250       260       270       280

        390       400       410       420       430       440      
pF1KB8 MHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSP
              290       300       310       320       330       340

        450       460       470       480       490       500      
pF1KB8 LGQKRGMLSSSTSGAISDKGVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGF
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 LGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGF
              350       360       370       380       390       400

        510       520       530       540       550       560      
pF1KB8 SIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLP
       ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_001 SIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLP
              410       420       430       440       450       460

        570       580       590       600       610       620      
pF1KB8 QPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLA
              470       480       490       500       510       520

        630       640       650       660       670       680      
pF1KB8 KRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGF
              530       540       550       560       570       580

        690       700       710       720       730       740      
pF1KB8 IITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIF
              590       600       610       620       630       640

        750       760       770       780       790       800      
pF1KB8 RKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQM
              650       660       670       680       690       700

        810       820       830       840       850       860  
pF1KB8 FASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              710       720       730       740       750      

>>NP_001308932 (OMIM: 276300,600259,614337) mismatch rep  (727 aa)
 initn: 4832 init1: 4832 opt: 4832  Z-score: 4038.9  bits: 758.2 E(85289): 3.1e-218
Smith-Waterman score: 4832; 99.7% identity (99.9% similar) in 727 aa overlap (136-862:1-727)

         110       120       130       140       150       160     
pF1KB8 FRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                     ::::::::::::::::::::::::::::::
NP_001                               MFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                             10        20        30

         170       180       190       200       210       220     
pF1KB8 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
               40        50        60        70        80        90

         230       240       250       260       270       280     
pF1KB8 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
              100       110       120       130       140       150

         290       300       310       320       330       340     
pF1KB8 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
              160       170       180       190       200       210

         350       360       370       380       390       400     
pF1KB8 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
              220       230       240       250       260       270

         410       420       430       440       450       460     
pF1KB8 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
              280       290       300       310       320       330

         470       480       490       500       510       520     
pF1KB8 GVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
              340       350       360       370       380       390

         530       540       550       560       570       580     
pF1KB8 DRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
       :::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
              400       410       420       430       440       450

         590       600       610       620       630       640     
pF1KB8 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
              460       470       480       490       500       510

         650       660       670       680       690       700     
pF1KB8 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
              520       530       540       550       560       570

         710       720       730       740       750       760     
pF1KB8 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
              580       590       600       610       620       630

         770       780       790       800       810       820     
pF1KB8 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
              640       650       660       670       680       690

         830       840       850       860  
pF1KB8 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       :::::::::::::::::::::::::::::::::::::
NP_001 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              700       710       720       

>>NP_001308933 (OMIM: 276300,600259,614337) mismatch rep  (727 aa)
 initn: 4832 init1: 4832 opt: 4832  Z-score: 4038.9  bits: 758.2 E(85289): 3.1e-218
Smith-Waterman score: 4832; 99.7% identity (99.9% similar) in 727 aa overlap (136-862:1-727)

         110       120       130       140       150       160     
pF1KB8 FRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                     ::::::::::::::::::::::::::::::
NP_001                               MFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                             10        20        30

         170       180       190       200       210       220     
pF1KB8 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
               40        50        60        70        80        90

         230       240       250       260       270       280     
pF1KB8 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
              100       110       120       130       140       150

         290       300       310       320       330       340     
pF1KB8 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
              160       170       180       190       200       210

         350       360       370       380       390       400     
pF1KB8 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
              220       230       240       250       260       270

         410       420       430       440       450       460     
pF1KB8 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
              280       290       300       310       320       330

         470       480       490       500       510       520     
pF1KB8 GVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
              340       350       360       370       380       390

         530       540       550       560       570       580     
pF1KB8 DRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
       :::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
              400       410       420       430       440       450

         590       600       610       620       630       640     
pF1KB8 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
              460       470       480       490       500       510

         650       660       670       680       690       700     
pF1KB8 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
              520       530       540       550       560       570

         710       720       730       740       750       760     
pF1KB8 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
              580       590       600       610       620       630

         770       780       790       800       810       820     
pF1KB8 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
              640       650       660       670       680       690

         830       840       850       860  
pF1KB8 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       :::::::::::::::::::::::::::::::::::::
NP_001 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              700       710       720       

>>NP_001308934 (OMIM: 276300,600259,614337) mismatch rep  (727 aa)
 initn: 4832 init1: 4832 opt: 4832  Z-score: 4038.9  bits: 758.2 E(85289): 3.1e-218
Smith-Waterman score: 4832; 99.7% identity (99.9% similar) in 727 aa overlap (136-862:1-727)

         110       120       130       140       150       160     
pF1KB8 FRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                     ::::::::::::::::::::::::::::::
NP_001                               MFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                             10        20        30

         170       180       190       200       210       220     
pF1KB8 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
               40        50        60        70        80        90

         230       240       250       260       270       280     
pF1KB8 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
              100       110       120       130       140       150

         290       300       310       320       330       340     
pF1KB8 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
              160       170       180       190       200       210

         350       360       370       380       390       400     
pF1KB8 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
              220       230       240       250       260       270

         410       420       430       440       450       460     
pF1KB8 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
              280       290       300       310       320       330

         470       480       490       500       510       520     
pF1KB8 GVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
              340       350       360       370       380       390

         530       540       550       560       570       580     
pF1KB8 DRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
       :::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
              400       410       420       430       440       450

         590       600       610       620       630       640     
pF1KB8 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
              460       470       480       490       500       510

         650       660       670       680       690       700     
pF1KB8 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
              520       530       540       550       560       570

         710       720       730       740       750       760     
pF1KB8 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
              580       590       600       610       620       630

         770       780       790       800       810       820     
pF1KB8 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
              640       650       660       670       680       690

         830       840       850       860  
pF1KB8 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       :::::::::::::::::::::::::::::::::::::
NP_001 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              700       710       720       

>>NP_001308942 (OMIM: 276300,600259,614337) mismatch rep  (671 aa)
 initn: 4164 init1: 4164 opt: 4164  Z-score: 3482.5  bits: 655.1 E(85289): 3.1e-187
Smith-Waterman score: 4333; 92.0% identity (92.2% similar) in 727 aa overlap (136-862:1-671)

         110       120       130       140       150       160     
pF1KB8 FRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                     ::::::::::::::::::::::::::::::
NP_001                               MFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                             10        20        30

         170       180       190       200       210       220     
pF1KB8 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
       ::::::::::::::                                              
NP_001 LPVRHKEFQRNIKK----------------------------------------------
               40                                                  

         230       240       250       260       270       280     
pF1KB8 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------LQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
                     50        60        70        80        90    

         290       300       310       320       330       340     
pF1KB8 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
          100       110       120       130       140       150    

         350       360       370       380       390       400     
pF1KB8 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
          160       170       180       190       200       210    

         410       420       430       440       450       460     
pF1KB8 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
          220       230       240       250       260       270    

         470       480       490       500       510       520     
pF1KB8 GVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
          280       290       300       310       320       330    

         530       540       550       560       570       580     
pF1KB8 DRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
       :::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
          340       350       360       370       380       390    

         590       600       610       620       630       640     
pF1KB8 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
          400       410       420       430       440       450    

         650       660       670       680       690       700     
pF1KB8 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
          460       470       480       490       500       510    

         710       720       730       740       750       760     
pF1KB8 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERA
          520       530       540       550       560       570    

         770       780       790       800       810       820     
pF1KB8 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTS
          580       590       600       610       620       630    

         830       840       850       860  
pF1KB8 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       :::::::::::::::::::::::::::::::::::::
NP_001 EMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
          640       650       660       670 

>>NP_001308938 (OMIM: 276300,600259,614337) mismatch rep  (738 aa)
 initn: 4818 init1: 4113 opt: 4113  Z-score: 3439.3  bits: 647.2 E(85289): 7.9e-185
Smith-Waterman score: 4800; 98.2% identity (98.4% similar) in 738 aa overlap (136-862:1-738)

         110       120       130       140       150       160     
pF1KB8 FRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                     ::::::::::::::::::::::::::::::
NP_001                               MFDHNGKIIQKTPYPRPRGTTVSVQQLFST
                                             10        20        30

         170       180       190       200       210       220     
pF1KB8 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKE
               40        50        60        70        80        90

         230       240       250       260       270       280     
pF1KB8 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSST
              100       110       120       130       140       150

         290       300       310       320       330       340     
pF1KB8 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILL
              160       170       180       190       200       210

         350       360       370       380       390       400     
pF1KB8 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPS
              220       230       240       250       260       270

         410       420       430       440       450       460     
pF1KB8 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDK
              280       290       300       310       320       330

         470       480       490       500       510       520     
pF1KB8 GVLRSQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPG
              340       350       360       370       380       390

         530       540       550       560       570       580     
pF1KB8 DRGSQEHVDSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
       :::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEIL
              400       410       420       430       440       450

         590       600       610       620       630       640     
pF1KB8 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNY
              460       470       480       490       500       510

         650       660       670       680       690       700     
pF1KB8 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDE
              520       530       540       550       560       570

         710       720       730       740       750               
pF1KB8 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEN-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_001 KYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENVMDFSQN
              580       590       600       610       620       630

          760       770       780       790       800       810    
pF1KB8 ----APVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRK
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CILLAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRK
              640       650       660       670       680       690

          820       830       840       850       860  
pF1KB8 SVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
              700       710       720       730        




862 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:40:36 2016 done: Sat Nov  5 20:40:38 2016
 Total Scan time: 13.230 Total Display time:  0.270

Function used was FASTA [36.3.4 Apr, 2011]
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