Result of FASTA (omim) for
pF1KB6826
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6826, 187 aa
1>>>pF1KB6826 187 - 187 aa - 187 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6590+/-0.000363; mu= 11.2015+/- 0.022
mean_var=67.8479+/-13.855, 0's: 0 Z-trim(113.4): 26 B-trim: 1705 in 2/53
Lambda= 0.155706
statistics sampled from 22699 (22717) to 22699 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.266), width: 16
Scan time: 4.750
The best scores are: opt bits E(85289)
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 1235 286.1 2.2e-77
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 380 94.0 1.6e-19
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 347 86.6 2.5e-17
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 346 86.4 3e-17
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 338 84.6 1e-16
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 335 83.9 1.6e-16
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 334 83.7 2e-16
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 331 83.0 3.1e-16
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 330 82.8 3.6e-16
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 325 81.7 7.8e-16
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 324 81.5 9.1e-16
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 312 78.8 5.9e-15
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 310 78.3 8.1e-15
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 310 78.3 8.1e-15
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 308 77.9 1.1e-14
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 291 74.0 1.6e-13
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 186 50.5 2.1e-06
>>NP_002167 (OMIM: 147640) interferon beta precursor [Ho (187 aa)
initn: 1235 init1: 1235 opt: 1235 Z-score: 1510.1 bits: 286.1 E(85289): 2.2e-77
Smith-Waterman score: 1235; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
130 140 150 160 170 180
pF1KB6 LTGYLRN
:::::::
NP_002 LTGYLRN
>>NP_795372 (OMIM: 615223) interferon epsilon precursor (208 aa)
initn: 370 init1: 320 opt: 380 Z-score: 471.4 bits: 94.0 E(85289): 1.6e-19
Smith-Waterman score: 380; 37.2% identity (68.3% similar) in 183 aa overlap (1-182:1-183)
10 20 30 40 50
pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNG-RLEYCLKDRMNF
: : .. .:.: ::: .:.. .:. : ::. : . ::: .:. .. :: : ::
NP_795 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 DIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHL
.:.. . ::.:: . ..::::.::..:: . : ::.:. .:..: ....:...:
NP_795 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 KTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFIN
.... . :: . : :. :..: :. :: ::. ..:: :::.::.::: : ..:.
NP_795 EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVF
130 140 150 160 170 180
180
pF1KB6 RLTGYLRN
::
NP_795 SLTEKLSKQGRPLNDMKQELTTEFRSPR
190 200
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 338 init1: 338 opt: 347 Z-score: 432.0 bits: 86.6 E(85289): 2.5e-17
Smith-Waterman score: 347; 37.2% identity (72.3% similar) in 148 aa overlap (41-186:40-186)
20 30 40 50 60
pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY--CLKDRMNFDIPEEIKQL
:: :. ::. . :::::..: .:.:. .
NP_002 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISHFSCLKDRYDFGFPQEVFDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE
.:::: .: ...::.:. : .: .::..:.::..... ....:.: :.. . ...
NP_002 NQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLEACVTQEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
:... . : : ...:. :: :: .:.:: ::: .::.::.:.: : . : ::
NP_002 VEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTNLQKGLRRK
130 140 150 160 170 180
NP_002 D
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 335 init1: 335 opt: 346 Z-score: 430.8 bits: 86.4 E(85289): 3e-17
Smith-Waterman score: 346; 33.9% identity (64.5% similar) in 183 aa overlap (6-186:8-186)
10 20 30 40 50
pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDR
:. ...: : : .:. . : . :: . .. :. ::. :::::
NP_002 MALPFVLLMALVVLNCKSICSLGCD---LPQTHSLSNRRTLMIMAQM-GRISPFSCLKDR
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 MNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQI
.: .:.: . .:::: .: ...::.:. : .: .::. :.::..... ...:.:.
NP_002 HDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 NHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFY
: :.. . ... :: .. : : ...:. :: :: :.:: ::: .::.::.:.:
NP_002 NDLEACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFS
120 130 140 150 160 170
180
pF1KB6 FINRLTGYLRN
. : ::
NP_002 LSANLQERLRRKE
180
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 331 init1: 331 opt: 338 Z-score: 421.0 bits: 84.6 E(85289): 1e-16
Smith-Waterman score: 338; 32.4% identity (65.4% similar) in 182 aa overlap (6-186:8-186)
10 20 30 40 50
pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY-CLKDRM
.. ...: : :. .:. . :. . .: . :. :. . :::::
NP_002 MALPFALMMALVVLSCKSSCSLGCN---LSQTHSLNNRRTLMLMAQMRRISPFSCLKDRH
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 NFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQIN
.:..:.: . .:::: .: ...::.:. : .: .::..:.::..:.. ....:.:
NP_002 DFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 HLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYF
:.. . ... :. . : : .:.:. :: :: :.:: ::: .::.::.:.. :
NP_002 DLEACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSF
120 130 140 150 160 170
180
pF1KB6 INRLTGYLRN
. : ::
NP_002 STNLQKRLRRKD
180
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 326 init1: 326 opt: 335 Z-score: 417.4 bits: 83.9 E(85289): 1.6e-16
Smith-Waterman score: 335; 37.2% identity (70.3% similar) in 148 aa overlap (41-186:40-186)
20 30 40 50 60
pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY--CLKDRMNFDIPEEIKQL
:: :. ::. . ::::: .: .::: .
NP_066 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISHFSCLKDRHDFGFPEEEFDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE
.:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.: :.. . ...
NP_066 HQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
:. . : : ...:. :: :: :.:: ::: .::.::.:.. : . : ::
NP_066 VEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRK
130 140 150 160 170 180
NP_066 D
>>NP_002168 (OMIM: 147553) interferon omega-1 precursor (195 aa)
initn: 351 init1: 328 opt: 334 Z-score: 416.0 bits: 83.7 E(85289): 2e-16
Smith-Waterman score: 334; 38.0% identity (73.7% similar) in 137 aa overlap (52-187:52-187)
30 40 50 60 70 80
pF1KB6 MSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIY
::::: .: .:.:. . .:.:: . ...
NP_002 LGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLH
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB6 EMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMS-S
::::.::..:. . ::..:: :....: .....:..::.: : . . : . : . : .
NP_002 EMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVV-GEGESAGAISSPA
90 100 110 120 130 140
150 160 170 180
pF1KB6 LHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
: :.::. : ::: :.:: ::: .::.::...... . . ::.
NP_002 LTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS
150 160 170 180 190
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 326 init1: 326 opt: 331 Z-score: 412.6 bits: 83.0 E(85289): 3.1e-16
Smith-Waterman score: 331; 36.5% identity (70.3% similar) in 148 aa overlap (41-186:40-186)
20 30 40 50 60
pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRMNFDIPEEIKQL
:: :. ::. ::::: .: .:.: .
NP_067 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISPFSCLKDRHDFGLPQEEFDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE
.:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.:.:.. . ...
NP_067 NQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
:. . : : ...:. :: :: :.:: ::: .::.::.:.. : . : ::
NP_067 MEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRK
130 140 150 160 170 180
NP_067 D
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 319 init1: 319 opt: 330 Z-score: 411.3 bits: 82.8 E(85289): 3.6e-16
Smith-Waterman score: 330; 35.3% identity (63.7% similar) in 190 aa overlap (6-186:7-186)
10 20 30 40 50
pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRM
::...:.: ... :.. .: . : . :: :. ::. :::::
NP_066 MARSFSLLMVVLVLSYKSIC-SLGCDL-PQTHSLRNRRALILLAQM-GRISPFSCLKDRH
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 NFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQIN
.: .::: . .:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.:
NP_066 EFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 HLKT-------VLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVE
:.. : : : .::: : ...:. :: :: :.:: ::: .::.:
NP_066 DLEACVIQEVGVEETPLMNEDFI-------LAVRKYFQRITLYLMEKKYSPCAWEVVRAE
120 130 140 150 160 170
180
pF1KB6 ILRNFYFINRLTGYLRN
:.:.: : . : ::
NP_066 IMRSFSFSTNLKKGLRRKD
180
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 320 init1: 320 opt: 325 Z-score: 405.3 bits: 81.7 E(85289): 7.8e-16
Smith-Waterman score: 325; 36.5% identity (69.6% similar) in 148 aa overlap (41-186:40-186)
20 30 40 50 60
pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRMNFDIPEEIKQL
:: :. ::. ::::: .: ::.: .
NP_002 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQM-GRISPFSCLKDRHDFRIPQEEFDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE
.:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.: :.. . ...
NP_002 NQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
:. . : : ...:. :: :: ..:: ::: .::.::.:.. : . : ::
NP_002 VEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRK
130 140 150 160 170 180
NP_002 D
187 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:27:20 2016 done: Sat Nov 5 20:27:20 2016
Total Scan time: 4.750 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]