Result of FASTA (omim) for pF1KB3103
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3103, 550 aa
  1>>>pF1KB3103 550 - 550 aa - 550 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8035+/-0.000491; mu= 0.2032+/- 0.031
 mean_var=335.9925+/-69.931, 0's: 0 Z-trim(118.3): 110  B-trim: 47 in 1/59
 Lambda= 0.069970
 statistics sampled from 31089 (31209) to 31089 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.366), width:  16
 Scan time:  9.910

The best scores are:                                      opt bits E(85289)
NP_005222 (OMIM: 164765) src substrate cortactin i ( 550) 3706 388.3 3.3e-107
NP_612632 (OMIM: 164765) src substrate cortactin i ( 513) 2574 274.0 7.8e-73
NP_001171669 (OMIM: 164765) src substrate cortacti ( 634) 2489 265.5 3.4e-70
XP_006718511 (OMIM: 164765) PREDICTED: src substra ( 369) 2347 251.0 4.9e-66
XP_006718510 (OMIM: 164765) PREDICTED: src substra ( 476) 2333 249.7 1.6e-65
XP_016872801 (OMIM: 164765) PREDICTED: src substra ( 277) 1812 196.8 7.3e-50
NP_005326 (OMIM: 601306) hematopoietic lineage cel ( 486) 1111 126.3 2.1e-28
NP_001278970 (OMIM: 601306) hematopoietic lineage  ( 449)  914 106.4   2e-22
NP_001271242 (OMIM: 610106) drebrin-like protein i ( 327)  317 46.0 0.00022
NP_001271244 (OMIM: 610106) drebrin-like protein i ( 336)  317 46.0 0.00022
NP_001014436 (OMIM: 610106) drebrin-like protein i ( 430)  317 46.1 0.00027
NP_054782 (OMIM: 610106) drebrin-like protein isof ( 431)  317 46.1 0.00027
XP_011513627 (OMIM: 610106) PREDICTED: drebrin-lik ( 438)  301 44.5 0.00082
NP_001116428 (OMIM: 610106) drebrin-like protein i ( 439)  301 44.5 0.00082


>>NP_005222 (OMIM: 164765) src substrate cortactin isofo  (550 aa)
 initn: 3706 init1: 3706 opt: 3706  Z-score: 2045.8  bits: 388.3 E(85289): 3.3e-107
Smith-Waterman score: 3706; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
              490       500       510       520       530       540

              550
pF1KB3 FPANYVELRQ
       ::::::::::
NP_005 FPANYVELRQ
              550

>>NP_612632 (OMIM: 164765) src substrate cortactin isofo  (513 aa)
 initn: 2739 init1: 2544 opt: 2574  Z-score: 1428.6  bits: 274.0 E(85289): 7.8e-73
Smith-Waterman score: 3375; 93.3% identity (93.3% similar) in 550 aa overlap (1-550:1-513)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       :::::::::::::::::::::::::                                   
NP_612 DRQDKCALGWDHQEKLQLHESQKDY-----------------------------------
              250       260                                        

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
           270       280       290       300       310       320   

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
           330       340       350       360       370       380   

              430       440       450       460       470       480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
           390       400       410       420       430       440   

              490       500       510       520       530       540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
           450       460       470       480       490       500   

              550
pF1KB3 FPANYVELRQ
       ::::::::::
NP_612 FPANYVELRQ
           510   

>>NP_001171669 (OMIM: 164765) src substrate cortactin is  (634 aa)
 initn: 5172 init1: 2447 opt: 2489  Z-score: 1381.1  bits: 265.5 E(85289): 3.4e-70
Smith-Waterman score: 3290; 92.9% identity (93.1% similar) in 538 aa overlap (1-538:1-501)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       :::::::::::::::::::::::::                                   
NP_001 DRQDKCALGWDHQEKLQLHESQKDY-----------------------------------
              250       260                                        

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
           270       280       290       300       310       320   

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
           330       340       350       360       370       380   

              430       440       450       460       470       480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
           390       400       410       420       430       440   

              490       500       510       520       530       540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.  
NP_001 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRFRE
           450       460       470       480       490       500   

              550                                                  
pF1KB3 FPANYVELRQ                                                  
                                                                   
NP_001 LAFSCVRVALVPIKCSRDLPGQARGLRSALWRVGRKDCPRRGASSRVSLLGRRGLGLMEV
           510       520       530       540       550       560   

>>XP_006718511 (OMIM: 164765) PREDICTED: src substrate c  (369 aa)
 initn: 2347 init1: 2347 opt: 2347  Z-score: 1306.5  bits: 251.0 E(85289): 4.9e-66
Smith-Waterman score: 2347; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
       :::::::::::::::::::::::::::::::::::::::::::::               
XP_006 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSFWEQLGPAQLPEPLG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
                                                                   
XP_006 RSCDRRKTS                                                   
                                                                   

>>XP_006718510 (OMIM: 164765) PREDICTED: src substrate c  (476 aa)
 initn: 2459 init1: 2313 opt: 2333  Z-score: 1297.5  bits: 249.7 E(85289): 1.6e-65
Smith-Waterman score: 3033; 86.5% identity (86.5% similar) in 550 aa overlap (1-550:1-476)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_006 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDY------------
              190       200       210       220                    

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
                                                                   
XP_006 ------------------------------------------------------------
                                                                   

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 --SKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
        230       240       250       260       270       280      

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
        290       300       310       320       330       340      

              430       440       450       460       470       480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
        350       360       370       380       390       400      

              490       500       510       520       530       540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
        410       420       430       440       450       460      

              550
pF1KB3 FPANYVELRQ
       ::::::::::
XP_006 FPANYVELRQ
        470      

>>XP_016872801 (OMIM: 164765) PREDICTED: src substrate c  (277 aa)
 initn: 1812 init1: 1812 opt: 1812  Z-score: 1016.2  bits: 196.8 E(85289): 7.3e-50
Smith-Waterman score: 1812; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       :::::::::::::::::::::::                                     
XP_016 DRQDKCALGWDHQEKLQLHESQKAREQTAIEPLFSAQ                       
              250       260       270                              

>>NP_005326 (OMIM: 601306) hematopoietic lineage cell-sp  (486 aa)
 initn: 1996 init1: 1049 opt: 1111  Z-score: 630.7  bits: 126.3 E(85289): 2.1e-28
Smith-Waterman score: 1353; 42.6% identity (65.9% similar) in 549 aa overlap (1-548:1-484)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       :::. .:: ::.. .  : :::.::::::::.:::::::::::..:::. ::::::.::.
NP_005 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       .: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...:
NP_005 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::.::. ::.:.:::::.:.:..:::.:::::: ::::.:::. :. ::.:.:.::.:
NP_005 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKG
     120       130       140       150       160       170         

              190       200       210        220       230         
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGF-EYQGKTEKHESQKDYVKGFGGKFGVQ
       .::::::::::.:::::.:::.::.:::::::: :... :  ...      . .:  :..
NP_005 ETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGTRGLK
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KB3 TDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQ
       .  ..        .:: . .: .:  .        :  ..:.  ::      : . .  :
NP_005 AKFESMA------EEKRKREEEEKAQQ--------VARRQQERKAV-----TKRSPEAPQ
     240             250       260               270            280

     300       310       320       330       340       350         
pF1KB3 QDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAK
          .             :.. :       ..::     : .   .:..  .:.. :. . 
NP_005 PVIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVP
                           290       300       310        320      

     360       370       380       390       400       410         
pF1KB3 EKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSP
           ..    . :.   .  .  :  ...   :: .      :   : :.: ..      
NP_005 LLPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND------
        330       340       350          360       370             

     420       430       440       450       460       470         
pF1KB3 VYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHY
        :::.     :.. .      : ::      .::.:.   .  .... :.  :.  :.  
NP_005 -YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGA
        380               390            400       410        420  

     480       490       500       510       520       530         
pF1KB3 PAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYG
        :   .       :::.::::::::. :.::.::::::.::.:::.:.::::: :.:..:
NP_005 GAGAVA-------LGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFG
                   430       440       450       460       470     

     540       550
pF1KB3 LFPANYVELRQ
       :::::::.:  
NP_005 LFPANYVKLLE
         480      

>>NP_001278970 (OMIM: 601306) hematopoietic lineage cell  (449 aa)
 initn: 1595 init1: 851 opt: 914  Z-score: 523.7  bits: 106.4 E(85289): 2e-22
Smith-Waterman score: 1099; 38.1% identity (61.1% similar) in 548 aa overlap (1-548:1-447)

               10        20        30        40        50        60
pF1KB3 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
       :::. .:: ::.. .  : :::.::::::::.:::::::::::..:::. ::::::.::.
NP_001 MWKSVVGHDVSVSVETQG-DDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRN
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB3 NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
       .: .::..:..::.:.::::::::::.::::.:::::::::::: ... :: ::.:...:
NP_001 KVSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKG
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB3 FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
       ::::.::. ::.:.:::::.:.:..:::.:::::..::::.::.: ::::::::::.   
NP_001 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYAKGFGGQYGIQKDRVDKSAVGFN---
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB3 KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
                               ...  .....   ::   :. .. ..:. .::  ..
NP_001 ------------------------EMEAPTTAYK---KTTPIEAASSGTRGLKAKFESMA
                                180          190       200         

              250       260       270       280       290       300
pF1KB3 DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
       ... :     ...:: :                 :  ..:.  ::      : . .  : 
NP_001 EEKRK----REEEEKAQQ----------------VARRQQERKAV-----TKRSPEAPQP
     210           220                       230            240    

              310       320       330       340       350       360
pF1KB3 DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
         .             :.. :       ..::     : .   .:..  .:.. :. .  
NP_001 VIA-------------MEEPAVPAPLPKKISSEAWPPVGTPP-SSESEPVRTSREHPVPL
                       250       260       270        280       290

              370       380       390       400       410       420
pF1KB3 KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
          ..    . :.   .  .  :  ...   :: .      :   : :.: ..       
NP_001 LPIRQTLPEDNEEPPALPPRTLEGLQVE---EEPVYEAEPEPEPEPEPEPEND-------
              300       310          320       330       340       

              430       440       450       460       470       480
pF1KB3 YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
       :::.     :.. .      : ::      .::.:.   .  .... :.  :.  :.   
NP_001 YEDVE----EMDRHEQ----EDEP-----EGDYEEVLEPEDSSFSS-ALAGSSGCPAGAG
                  350                360       370        380      

              490       500       510       520       530       540
pF1KB3 AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
       :   .       :::.::::::::. :.::.::::::.::.:::.:.::::: :.:..::
NP_001 AGAVA-------LGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGL
        390              400       410       420       430         

              550
pF1KB3 FPANYVELRQ
       ::::::.:  
NP_001 FPANYVKLLE
     440         

>>NP_001271242 (OMIM: 610106) drebrin-like protein isofo  (327 aa)
 initn: 339 init1: 206 opt: 317  Z-score: 199.7  bits: 46.0 E(85289): 0.00022
Smith-Waterman score: 344; 32.6% identity (52.8% similar) in 307 aa overlap (303-548:30-325)

            280       290       300       310       320            
pF1KB3 FGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDV---TQ
                                     .:. :..:. .:.     .. :.::   . 
NP_001  MASFLKGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKE-----SGRFQDVGPQAP
                10        20        30        40             50    

     330       340       350       360          370        380     
pF1KB3 VSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRR---KAEAERAQR-MAKERQEQE
       :.:.::::   .::.      . .:   : :::.:.::   : .::.::: . .::.:.:
NP_001 VGSVYQKT---NAVSEIKRVGKDSFWAKA-EKEEENRRLEEKRRAEEAQRQLEQERRERE
           60           70        80         90       100       110

            390       400                                          
pF1KB3 ---EARRKLEEQARAKTQTPP--------------------VSP----------------
           :::. . : ..   .:                     : :                
NP_001 LREAARREQRYQEQGGEASPQRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTSI
              120       130       140       150       160       170

         410             420              430       440       450  
pF1KB3 -APQPTEERLP------SSPV----YEDAASF---KAELSYRGPVSGTEPEPVYSMEAAD
        .::: . : :      ..:      : ::..   .:.:  . :. .: :  : . : : 
NP_001 SSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEAV
              180       190       200       210       220       230

            460       470       480       490       500       510  
pF1KB3 YREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEIS
       :.:   :. .      : ... .  :   .     .  .  :. : :::::::: : :::
NP_001 YEEPPEQETFYEQPPLVQQQGAGSEH--IDHHIQGQGLSGQGLCARALYDYQAADDTEIS
              240       250         260       270       280        

            520       530        540       550
pF1KB3 FDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVELRQ
       :::...::.::.::.:::::    :..:.::::::::  
NP_001 FDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
      290       300       310       320       

>>NP_001271244 (OMIM: 610106) drebrin-like protein isofo  (336 aa)
 initn: 339 init1: 206 opt: 317  Z-score: 199.6  bits: 46.0 E(85289): 0.00022
Smith-Waterman score: 342; 32.5% identity (52.6% similar) in 308 aa overlap (303-548:38-334)

            280       290       300       310       320            
pF1KB3 FGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDV---TQ
                                     .:. :..:. .:.     .. :.::   . 
NP_001 SAWLAQGGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKE-----SGRFQDVGPQAP
        10        20        30        40        50             60  

     330       340       350       360          370        380     
pF1KB3 VSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRR---KAEAERAQR-MAKERQEQE
       :.:.::::   .::.      . .:   : :::.:.::   : .::.::: . .::.:.:
NP_001 VGSVYQKT---NAVSEIKRVGKDSFWAKA-EKEEENRRLEEKRRAEEAQRQLEQERRERE
             70           80         90       100       110        

            390       400                                          
pF1KB3 ---EARRKLEEQARAKTQTPP---------------------VSP---------------
           :::. . : ..   .:                      : :               
NP_001 LREAARREQRYQEQGGEASPQSRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTS
      120       130       140       150       160       170        

          410             420              430       440       450 
pF1KB3 --APQPTEERLP------SSPV----YEDAASF---KAELSYRGPVSGTEPEPVYSMEAA
         .::: . : :      ..:      : ::..   .:.:  . :. .: :  : . : :
NP_001 ISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEA
      180       190       200       210       220       230        

             460       470       480       490       500       510 
pF1KB3 DYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEI
        :.:   :. .      : ... .  :   .     .  .  :. : :::::::: : ::
NP_001 VYEEPPEQETFYEQPPLVQQQGAGSEH--IDHHIQGQGLSGQGLCARALYDYQAADDTEI
      240       250       260         270       280       290      

             520       530        540       550
pF1KB3 SFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVELRQ
       ::::...::.::.::.:::::    :..:.::::::::  
NP_001 SFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
        300       310       320       330      




550 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:53:28 2016 done: Fri Nov  4 23:53:29 2016
 Total Scan time:  9.910 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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