Result of FASTA (omim) for pF1KE1014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1014, 302 aa
  1>>>pF1KE1014 302 - 302 aa - 302 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3506+/-0.000402; mu= 15.4605+/- 0.025
 mean_var=84.1021+/-17.205, 0's: 0 Z-trim(112.1): 184  B-trim: 0 in 0/61
 Lambda= 0.139853
 statistics sampled from 20693 (20894) to 20693 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.245), width:  16
 Scan time:  7.460

The best scores are:                                      opt bits E(85289)
NP_056074 (OMIM: 605717) ICOS ligand isoform a pre ( 302) 2005 414.6 1.2e-115
XP_011527817 (OMIM: 605717) PREDICTED: ICOS ligand ( 304) 1982 410.0 3.1e-114
NP_001269979 (OMIM: 605717) ICOS ligand isoform b  ( 309) 1982 410.0 3.1e-114
XP_011527816 (OMIM: 605717) PREDICTED: ICOS ligand ( 361) 1982 410.0 3.5e-114
XP_016883799 (OMIM: 605717) PREDICTED: ICOS ligand ( 275) 1837 380.7 1.8e-105
XP_011527818 (OMIM: 605717) PREDICTED: ICOS ligand ( 334) 1814 376.1 5.2e-104
NP_001269981 (OMIM: 605717) ICOS ligand isoform d  ( 217) 1446 301.7 8.5e-82
NP_001269980 (OMIM: 605717) ICOS ligand isoform c  ( 185) 1124 236.7 2.7e-62
NP_079516 (OMIM: 605715) CD276 antigen isoform b p ( 316)  340 78.7 1.7e-14
NP_001316557 (OMIM: 605715) CD276 antigen isoform  ( 316)  340 78.7 1.7e-14
NP_001316558 (OMIM: 605715) CD276 antigen isoform  ( 388)  322 75.1 2.4e-13
XP_011520397 (OMIM: 605715) PREDICTED: CD276 antig ( 534)  322 75.2 3.1e-13
XP_016878127 (OMIM: 605715) PREDICTED: CD276 antig ( 534)  322 75.2 3.1e-13
XP_011520398 (OMIM: 605715) PREDICTED: CD276 antig ( 534)  322 75.2 3.1e-13
NP_001019907 (OMIM: 605715) CD276 antigen isoform  ( 534)  322 75.2 3.1e-13
XP_005254757 (OMIM: 605715) PREDICTED: CD276 antig ( 534)  322 75.2 3.1e-13
NP_001723 (OMIM: 601610) butyrophilin subfamily 1  ( 526)  234 57.5 6.8e-08
NP_795711 (OMIM: 601020) T-lymphocyte activation a ( 275)  230 56.4 7.3e-08
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626)  234 57.5 7.7e-08
NP_008820 (OMIM: 601020) T-lymphocyte activation a ( 323)  219 54.3 3.8e-07
NP_787058 (OMIM: 601020) T-lymphocyte activation a ( 329)  219 54.3 3.9e-07
XP_016863009 (OMIM: 112203) PREDICTED: T-lymphocyt ( 249)  217 53.8 4.2e-07
NP_005182 (OMIM: 112203) T-lymphocyte activation a ( 288)  215 53.4 6.2e-07
XP_005248888 (OMIM: 613594) PREDICTED: butyrophili ( 267)  198 50.0 6.3e-06
XP_005248889 (OMIM: 613594) PREDICTED: butyrophili ( 267)  198 50.0 6.3e-06
XP_016866546 (OMIM: 606000,612387) PREDICTED: buty ( 482)  201 50.8 6.4e-06
NP_001291490 (OMIM: 606000,612387) butyrophilin-li ( 482)  201 50.8 6.4e-06
NP_001184177 (OMIM: 613594) butyrophilin subfamily ( 311)  194 49.2 1.2e-05
XP_016865705 (OMIM: 613594) PREDICTED: butyrophili ( 225)  192 48.7 1.3e-05
NP_001184175 (OMIM: 613594) butyrophilin subfamily ( 334)  194 49.2 1.3e-05
XP_016865700 (OMIM: 613594) PREDICTED: butyrophili ( 334)  194 49.2 1.3e-05
NP_001184176 (OMIM: 613594) butyrophilin subfamily ( 334)  194 49.2 1.3e-05
XP_005248884 (OMIM: 613594) PREDICTED: butyrophili ( 334)  194 49.2 1.3e-05
XP_016865701 (OMIM: 613594) PREDICTED: butyrophili ( 334)  194 49.2 1.3e-05
NP_008978 (OMIM: 613594) butyrophilin subfamily 3  ( 334)  194 49.2 1.3e-05
XP_006715044 (OMIM: 613594) PREDICTED: butyrophili ( 339)  194 49.2 1.3e-05
XP_011512569 (OMIM: 613594) PREDICTED: butyrophili ( 339)  194 49.2 1.3e-05
XP_006715042 (OMIM: 613594) PREDICTED: butyrophili ( 339)  194 49.2 1.3e-05
XP_006715043 (OMIM: 613594) PREDICTED: butyrophili ( 339)  194 49.2 1.3e-05
XP_011512570 (OMIM: 613594) PREDICTED: butyrophili ( 339)  194 49.2 1.3e-05
NP_001184163 (OMIM: 613590) butyrophilin subfamily ( 330)  192 48.8 1.7e-05
NP_510961 (OMIM: 613590) butyrophilin subfamily 2  ( 334)  192 48.8 1.7e-05
XP_016865703 (OMIM: 613594) PREDICTED: butyrophili ( 292)  188 48.0 2.7e-05
NP_001184178 (OMIM: 613594) butyrophilin subfamily ( 292)  188 48.0 2.7e-05
XP_011512571 (OMIM: 613594) PREDICTED: butyrophili ( 297)  188 48.0 2.8e-05
XP_006715045 (OMIM: 613594) PREDICTED: butyrophili ( 297)  188 48.0 2.8e-05
XP_016865702 (OMIM: 613594) PREDICTED: butyrophili ( 297)  188 48.0 2.8e-05
XP_011511629 (OMIM: 112203) PREDICTED: T-lymphocyt ( 217)  186 47.5 2.9e-05
NP_001300958 (OMIM: 605402) programmed cell death  ( 245)  183 46.9 4.8e-05
NP_001184167 (OMIM: 613591) butyrophilin subfamily ( 336)  184 47.2 5.3e-05


>>NP_056074 (OMIM: 605717) ICOS ligand isoform a precurs  (302 aa)
 initn: 2005 init1: 2005 opt: 2005  Z-score: 2197.1  bits: 414.6 E(85289): 1.2e-115
Smith-Waterman score: 2005; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
              250       260       270       280       290       300

         
pF1KE1 HV
       ::
NP_056 HV
         

>>XP_011527817 (OMIM: 605717) PREDICTED: ICOS ligand iso  (304 aa)
 initn: 1982 init1: 1982 opt: 1982  Z-score: 2172.0  bits: 410.0 E(85289): 3.1e-114
Smith-Waterman score: 1982; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTV
              250       260       270       280       290       300

           
pF1KE1 HV  
           
XP_011 PGAT
           

>>NP_001269979 (OMIM: 605717) ICOS ligand isoform b prec  (309 aa)
 initn: 1982 init1: 1982 opt: 1982  Z-score: 2171.9  bits: 410.0 E(85289): 3.1e-114
Smith-Waterman score: 1982; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTE
              250       260       270       280       290       300

                
pF1KE1 HV       
                
NP_001 SWNLLLLLS
                

>>XP_011527816 (OMIM: 605717) PREDICTED: ICOS ligand iso  (361 aa)
 initn: 1982 init1: 1982 opt: 1982  Z-score: 2171.0  bits: 410.0 E(85289): 3.5e-114
Smith-Waterman score: 1982; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTV
              250       260       270       280       290       300

                                                                   
pF1KE1 HV                                                          
                                                                   
XP_011 SRHGFEQTTDVLPFILKSSLGASCEPTAFPLPPAAPGPCAHLFIWMLAECTPCSPVWSSI
              310       320       330       340       350       360

>>XP_016883799 (OMIM: 605717) PREDICTED: ICOS ligand iso  (275 aa)
 initn: 1837 init1: 1837 opt: 1837  Z-score: 2014.5  bits: 380.7 E(85289): 1.8e-105
Smith-Waterman score: 1837; 100.0% identity (100.0% similar) in 275 aa overlap (28-302:1-275)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
                                  :::::::::::::::::::::::::::::::::
XP_016                            MVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
                                          10        20        30   

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
            40        50        60        70        80        90   

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
           100       110       120       130       140       150   

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
           160       170       180       190       200       210   

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
           220       230       240       250       260       270   

         
pF1KE1 HV
       ::
XP_016 HV
         

>>XP_011527818 (OMIM: 605717) PREDICTED: ICOS ligand iso  (334 aa)
 initn: 1814 init1: 1814 opt: 1814  Z-score: 1988.2  bits: 376.1 E(85289): 5.2e-104
Smith-Waterman score: 1814; 100.0% identity (100.0% similar) in 272 aa overlap (28-299:1-272)

               10        20        30        40        50        60
pF1KE1 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
                                  :::::::::::::::::::::::::::::::::
XP_011                            MVGSDVELSCACPEGSRFDLNDVYVYWQTSESK
                                          10        20        30   

               70        80        90       100       110       120
pF1KE1 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSL
            40        50        60        70        80        90   

              130       140       150       160       170       180
pF1KE1 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLL
           100       110       120       130       140       150   

              190       200       210       220       230       240
pF1KE1 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERD
           160       170       180       190       200       210   

              250       260       270       280       290       300
pF1KE1 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 KITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTV
           220       230       240       250       260       270   

                                                                   
pF1KE1 HV                                                          
                                                                   
XP_011 SRHGFEQTTDVLPFILKSSLGASCEPTAFPLPPAAPGPCAHLFIWMLAECTPCSPVWSSI
           280       290       300       310       320       330   

>>NP_001269981 (OMIM: 605717) ICOS ligand isoform d [Hom  (217 aa)
 initn: 1446 init1: 1446 opt: 1446  Z-score: 1589.5  bits: 301.7 E(85289): 8.5e-82
Smith-Waterman score: 1446; 100.0% identity (100.0% similar) in 217 aa overlap (86-302:1-217)

          60        70        80        90       100       110     
pF1KE1 TSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLV
                                     ::::::::::::::::::::::::::::::
NP_001                               MSPAGMLRGDFSLRLFNVTPQDEQKFHCLV
                                             10        20        30

         120       130       140       150       160       170     
pF1KE1 LSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKT
               40        50        60        70        80        90

         180       190       200       210       220       230     
pF1KE1 DNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGND
              100       110       120       130       140       150

         240       250       260       270       280       290     
pF1KE1 IGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPE
              160       170       180       190       200       210

         300  
pF1KE1 TELTGHV
       :::::::
NP_001 TELTGHV
              

>>NP_001269980 (OMIM: 605717) ICOS ligand isoform c prec  (185 aa)
 initn: 1124 init1: 1124 opt: 1124  Z-score: 1239.3  bits: 236.7 E(85289): 2.7e-62
Smith-Waterman score: 1124; 100.0% identity (100.0% similar) in 168 aa overlap (135-302:18-185)

          110       120       130       140       150       160    
pF1KE1 PQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGY
                                     ::::::::::::::::::::::::::::::
NP_001              MRLGSPGLLFLLFSSLRAANFSVPVVSAPHSPSQDELTFTCTSINGY
                            10        20        30        40       

          170       180       190       200       210       220    
pF1KE1 PRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQ
        50        60        70        80        90       100       

          230       240       250       260       270       280    
pF1KE1 NLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQH
       110       120       130       140       150       160       

          290       300  
pF1KE1 SYAGAWAVSPETELTGHV
       ::::::::::::::::::
NP_001 SYAGAWAVSPETELTGHV
       170       180     

>>NP_079516 (OMIM: 605715) CD276 antigen isoform b precu  (316 aa)
 initn: 251 init1:  83 opt: 340  Z-score: 381.3  bits: 78.7 E(85289): 1.7e-14
Smith-Waterman score: 367; 30.5% identity (56.5% similar) in 308 aa overlap (2-289:4-285)

                            10        20        30        40       
pF1KE1   MRLGSPG-----------LLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDL
          : ::::           : : : ..:.... :  : :.::.:. : :.      :.:
NP_079 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
               10        20        30        40        50        60

        50        60        70          80        90       100     
pF1KE1 NDVYVYWQTSESKTVVTYHIPQNSSLENVD--SRYRNRALMSPAGMLRGDFSLRLFNVTP
        .. . :: ...: .:      .:  :. :  : : ::. . :  . .:. ::::  :  
NP_079 AQLNLIWQLTDTKQLV------HSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRV
               70              80        90       100       110    

         110       120       130       140        150         160  
pF1KE1 QDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVS-APHSPSQ--DELTFTCTSIN
        :: .: :.:  ...:     :. :.:.::: .: : ..  :..  .  : .:.::.:  
NP_079 ADEGSFTCFVSIRDFG-----SAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYR
          120       130            140       150       160         

            170       180       190       200       210       220  
pF1KE1 GYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLL
       :::. .:.: .     :  ..  .. .  : .::.:: ::::..   . . .: ..: .:
NP_079 GYPEAEVFWQDGQGVPLTGNVTTSQMA--NEQGLFDVHSVLRVVLGANGTYSCLVRNPVL
     170       180       190         200       210       220       

            230       240       250       260       270            
pF1KE1 QQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVC----R
       ::.   :: :         :: .:..   .  : :  ...   :... ::...::    .
NP_079 QQDAH-GSVT---------ITGQPMTFPPE--ALWVTVGLSVCLIALLVALAFVCWRKIK
       230                 240         250       260       270     

      280       290       300                    
pF1KE1 DRCLQHSYAGAWAVSPETELTGHV                  
       . : ... :::                               
NP_079 QSCEEEN-AGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
         280        290       300       310      

>>NP_001316557 (OMIM: 605715) CD276 antigen isoform b pr  (316 aa)
 initn: 251 init1:  83 opt: 340  Z-score: 381.3  bits: 78.7 E(85289): 1.7e-14
Smith-Waterman score: 367; 30.5% identity (56.5% similar) in 308 aa overlap (2-289:4-285)

                            10        20        30        40       
pF1KE1   MRLGSPG-----------LLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDL
          : ::::           : : : ..:.... :  : :.::.:. : :.      :.:
NP_001 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
               10        20        30        40        50        60

        50        60        70          80        90       100     
pF1KE1 NDVYVYWQTSESKTVVTYHIPQNSSLENVD--SRYRNRALMSPAGMLRGDFSLRLFNVTP
        .. . :: ...: .:      .:  :. :  : : ::. . :  . .:. ::::  :  
NP_001 AQLNLIWQLTDTKQLV------HSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRV
               70              80        90       100       110    

         110       120       130       140        150         160  
pF1KE1 QDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVS-APHSPSQ--DELTFTCTSIN
        :: .: :.:  ...:     :. :.:.::: .: : ..  :..  .  : .:.::.:  
NP_001 ADEGSFTCFVSIRDFG-----SAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYR
          120       130            140       150       160         

            170       180       190       200       210       220  
pF1KE1 GYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLL
       :::. .:.: .     :  ..  .. .  : .::.:: ::::..   . . .: ..: .:
NP_001 GYPEAEVFWQDGQGVPLTGNVTTSQMA--NEQGLFDVHSVLRVVLGANGTYSCLVRNPVL
     170       180       190         200       210       220       

            230       240       250       260       270            
pF1KE1 QQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVC----R
       ::.   :: :         :: .:..   .  : :  ...   :... ::...::    .
NP_001 QQDAH-GSVT---------ITGQPMTFPPE--ALWVTVGLSVCLIALLVALAFVCWRKIK
       230                 240         250       260       270     

      280       290       300                    
pF1KE1 DRCLQHSYAGAWAVSPETELTGHV                  
       . : ... :::                               
NP_001 QSCEEEN-AGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
         280        290       300       310      




302 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:24:33 2016 done: Sat Nov  5 13:24:34 2016
 Total Scan time:  7.460 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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