Result of FASTA (ccds) for pF1KB5307
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5307, 412 aa
  1>>>pF1KB5307 412 - 412 aa - 412 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3489+/-0.000878; mu= 16.9952+/- 0.053
 mean_var=68.1203+/-13.847, 0's: 0 Z-trim(106.1): 25  B-trim: 0 in 0/49
 Lambda= 0.155395
 statistics sampled from 8759 (8773) to 8759 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.269), width:  16
 Scan time:  2.880

The best scores are:                                      opt bits E(32554)
CCDS10705.1 BCKDK gene_id:10295|Hs108|chr16        ( 412) 2751 625.8 2.3e-179
CCDS45467.1 BCKDK gene_id:10295|Hs108|chr16        ( 365) 2442 556.5 1.5e-158
CCDS61917.1 BCKDK gene_id:10295|Hs108|chr16        ( 335) 1881 430.7 9.9e-121
CCDS2250.1 PDK1 gene_id:5163|Hs108|chr2            ( 436)  289 73.9 3.4e-13
CCDS11559.1 PDK2 gene_id:5164|Hs108|chr17          ( 407)  288 73.6 3.7e-13
CCDS5643.1 PDK4 gene_id:5166|Hs108|chr7            ( 411)  279 71.6 1.5e-12


>>CCDS10705.1 BCKDK gene_id:10295|Hs108|chr16             (412 aa)
 initn: 2751 init1: 2751 opt: 2751  Z-score: 3333.7  bits: 625.8 E(32554): 2.3e-179
Smith-Waterman score: 2751; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)

               10        20        30        40        50        60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
              310       320       330       340       350       360

              370       380       390       400       410  
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
              370       380       390       400       410  

>>CCDS45467.1 BCKDK gene_id:10295|Hs108|chr16             (365 aa)
 initn: 2442 init1: 2442 opt: 2442  Z-score: 2960.1  bits: 556.5 E(32554): 1.5e-158
Smith-Waterman score: 2442; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)

               10        20        30        40        50        60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
              310       320       330       340       350       360

              370       380       390       400       410  
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
       :::::                                               
CCDS45 GPMHG                                               
                                                           

>>CCDS61917.1 BCKDK gene_id:10295|Hs108|chr16             (335 aa)
 initn: 1881 init1: 1881 opt: 1881  Z-score: 2281.0  bits: 430.7 E(32554): 9.9e-121
Smith-Waterman score: 2181; 91.8% identity (91.8% similar) in 365 aa overlap (1-365:1-335)

               10        20        30        40        50        60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
       ::::::::::::::::::::::::::::::::::::::::::                  
CCDS61 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMR------------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 ------------ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
                        290       300       310       320       330

              370       380       390       400       410  
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
       :::::                                               
CCDS61 GPMHG                                               
                                                           

>>CCDS2250.1 PDK1 gene_id:5163|Hs108|chr2                 (436 aa)
 initn: 540 init1: 146 opt: 289  Z-score: 350.4  bits: 73.9 E(32554): 3.4e-13
Smith-Waterman score: 552; 32.9% identity (61.2% similar) in 340 aa overlap (93-407:78-398)

             70        80        90       100       110       120  
pF1KB5 AEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTI
                                     .:.::::::.:. .: .  ::  .  .:..
CCDS22 FYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSV
        50        60        70        80        90       100       

            130       140        150           160       170       
pF1KB5 LHVHELYIRAFQKLTDFPPIKDQ-ADEAQ----YCQLVRQLLDDHKDVVTLLAEGLRESR
         :.  ::...:.: ::   ::. :..:.    . . : .. . :.::.  .:.:. : .
CCDS22 QLVQSWYIQSLQELLDF---KDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYK
       110       120          130       140       150       160    

       180           190       200       210              220      
pF1KB5 KHIEDEKL----VRYFLDKTLTSRLGIRMLATHHLALHEDK----PDF---VGIICTRLS
       . .  . .    :.::::.   ::..:::: ..:  :   :    :.    .: :    .
CCDS22 ESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCN
          170       180       190       200       210       220    

        230       240       250       260              270         
pF1KB5 PKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFP-------FIPMPLDYILPELLKN
         ..:.   . :::::.  : :.:..... .. :. :       ..:  : ... ::.::
CCDS22 VLEVIKDGYENARRLCDLYYINSPELELE-ELNAKSPGQPIQVVYVPSHLYHMVFELFKN
          230       240       250        260       270       280   

     280       290       300       310       320       330         
pF1KB5 AMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEAS
       ::::::: : .     : . . .. .. :: ...::::::.  . .::...: ..::   
CCDS22 AMRATMEHHANRGV-YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR-
           290        300       310       320       330       340  

     340       350       360       370       380       390         
pF1KB5 TQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTD--VY
          ::.            ... :. :::.::: :: ::.:. :.:.: ::.: :::  .:
CCDS22 ---PRVET----------SRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIY
                          350       360       370       380        

       400       410                                   
pF1KB5 LRLRHIDGREESFRI                                 
       ..    :. :                                      
CCDS22 IKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA
      390       400       410       420       430      

>>CCDS11559.1 PDK2 gene_id:5164|Hs108|chr17               (407 aa)
 initn: 448 init1: 149 opt: 288  Z-score: 349.6  bits: 73.6 E(32554): 3.7e-13
Smith-Waterman score: 565; 32.8% identity (60.7% similar) in 338 aa overlap (90-407:49-369)

      60        70        80        90       100       110         
pF1KB5 DAAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCN
                                     :  .:.::::::.:. .: .  ::  .  .
CCDS11 YIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLST
       20        30        40        50        60        70        

     120       130       140       150          160       170      
pF1KB5 PTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLL---DDHKDVVTLLAEGLRES
       :..  :.  :....  . .:   ::  :.    :..  :.   . :.:::  .:.:. : 
CCDS11 PSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEY
       80        90       100        110       120       130       

        180           190       200       210            220       
pF1KB5 RKHIEDEKL----VRYFLDKTLTSRLGIRMLATHHLALHEDK-----PDFVGIICTRLSP
       .    :. .    ..::::.   ::..:::: ..:  . . .     :  .: :    . 
CCDS11 KDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNV
       140       150       160       170       180       190       

       230       240       250       260             270       280 
pF1KB5 KKIIEKWVDFARRLCEHKYGNAPRVRINGHVAA--RFP----FIPMPLDYILPELLKNAM
       .....   :.:. ::.. :  .: ..:.   ::  . :    ..:  : ..: ::.::::
CCDS11 SEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAM
       200       210       220       230       240       250       

             290       300       310       320       330       340 
pF1KB5 RATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQ
       :::.::: ..   .: . . .: .. :: :..::::::.  . ..:...: ..::     
CCDS11 RATVESH-ESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTA-----
       260        270       280       290       300       310      

             350       360       370       380       390           
pF1KB5 DPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTD--VYLR
        :  .:         :. . :. :::.::: :: ::.:. :.::: :..:.:::  .::.
CCDS11 -PTPQP---------GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK
                       320       330       340       350       360 

     400       410                                   
pF1KB5 LRHIDGREESFRI                                 
           :. :                                      
CCDS11 ALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
             370       380       390       400       

>>CCDS5643.1 PDK4 gene_id:5166|Hs108|chr7                 (411 aa)
 initn: 462 init1: 144 opt: 279  Z-score: 338.7  bits: 71.6 E(32554): 1.5e-12
Smith-Waterman score: 534; 31.1% identity (63.4% similar) in 328 aa overlap (93-401:56-365)

             70        80        90       100       110       120  
pF1KB5 AEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTI
                                     .:.::::::.:. .: .  ::  .  . ..
CCDS56 HFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSV
          30        40        50        60        70        80     

            130          140       150       160       170         
pF1KB5 LHVHELYIRAFQKLTDF---PPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKH
         :.  ::.... :..:    :  ::   ... . . .. . :..::  .:.:. : .  
CCDS56 QLVKSWYIQSLMDLVEFHEKSP-DDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDA
          90       100        110       120       130       140    

          180       190       200       210           220       230
pF1KB5 -----IEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK----PDFVGIICTRLSPKKI
            . ...: .::::.   .:.. ::: ..:. .  :.    :. .: :    .   .
CCDS56 CTVDPVTNQNL-QYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAV
          150        160       170       180       190       200   

              240       250       260              270       280   
pF1KB5 IEKWVDFARRLCEHKYGNAPRVRINGHVAARFP-------FIPMPLDYILPELLKNAMRA
       ..   . .: ::.. : ..:..... .: ..::       ..:  : ..: ::.::::::
CCDS56 VQDAFECSRMLCDQYYLSSPELKLT-QVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRA
           210       220        230       240       250       260  

           290       300       310       320       330       340   
pF1KB5 TMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDP
       :.: . . :  .:  ::.. ... :: :.:::::::.  . .::...: ..:: . ..: 
CCDS56 TVEHQENQPSLTPIEVIVVLGKE-DLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMD-
            270       280        290       300       310       320 

           350       360       370       380       390       400   
pF1KB5 RISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI
                    .....:. :::.::: :: ::.:. :.:.: ::.: :::. . :.  
CCDS56 -------------NSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKAL
                           330       340       350       360       

           410                                     
pF1KB5 DGREESFRI                                   
                                                   
CCDS56 SSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM
       370       380       390       400       410 




412 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:27:40 2016 done: Sat Nov  5 12:27:41 2016
 Total Scan time:  2.880 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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