Result of FASTA (omim) for pF1KB5907
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5907, 504 aa
  1>>>pF1KB5907 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4668+/-0.000508; mu= -1.8559+/- 0.031
 mean_var=221.4123+/-45.808, 0's: 0 Z-trim(115.7): 97  B-trim: 883 in 2/53
 Lambda= 0.086193
 statistics sampled from 26190 (26287) to 26190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.308), width:  16
 Scan time:  9.080

The best scores are:                                      opt bits E(85289)
NP_000252 (OMIM: 137750,601652) myocilin precursor ( 504) 3319 426.1 1.2e-118
NP_001269541 (OMIM: 605366) noelin isoform 5 [Homo ( 458)  757 107.5 8.6e-23
NP_055094 (OMIM: 605366) noelin isoform 1 precurso ( 467)  757 107.5 8.7e-23
NP_001269540 (OMIM: 605366) noelin isoform 4 precu ( 485)  757 107.5   9e-23
NP_477518 (OMIM: 607567) noelin-3 isoform 2 precur ( 458)  676 97.4 9.2e-20
NP_001275750 (OMIM: 607567) noelin-3 isoform 1 pre ( 478)  676 97.4 9.6e-20
NP_001275752 (OMIM: 607567) noelin-3 isoform 3 [Ho ( 383)  673 97.0   1e-19
XP_016855729 (OMIM: 607567) PREDICTED: noelin-3 is ( 383)  673 97.0   1e-19
XP_016863431 (OMIM: 616417) PREDICTED: adhesion G  (1235)  616 90.2 3.7e-17
NP_001309175 (OMIM: 616417) adhesion G protein-cou (1240)  616 90.2 3.7e-17
XP_016863430 (OMIM: 616417) PREDICTED: adhesion G  (1299)  616 90.2 3.8e-17
XP_016863429 (OMIM: 616417) PREDICTED: adhesion G  (1308)  616 90.2 3.8e-17
NP_001269644 (OMIM: 615899) olfactomedin-like prot ( 438)  605 88.6 4.1e-17
XP_016863428 (OMIM: 616417) PREDICTED: adhesion G  (1442)  616 90.3 4.2e-17
NP_056051 (OMIM: 616417) adhesion G protein-couple (1469)  616 90.3 4.2e-17
XP_016863427 (OMIM: 616417) PREDICTED: adhesion G  (1510)  616 90.3 4.3e-17
XP_011530093 (OMIM: 616417) PREDICTED: adhesion G  (1515)  616 90.3 4.3e-17
XP_016863426 (OMIM: 616417) PREDICTED: adhesion G  (1518)  616 90.3 4.3e-17
XP_016863425 (OMIM: 616417) PREDICTED: adhesion G  (1524)  616 90.3 4.3e-17
XP_016863424 (OMIM: 616417) PREDICTED: adhesion G  (1528)  616 90.3 4.4e-17
XP_016863423 (OMIM: 616417) PREDICTED: adhesion G  (1532)  616 90.3 4.4e-17
XP_016863422 (OMIM: 616417) PREDICTED: adhesion G  (1534)  616 90.3 4.4e-17
NP_001309331 (OMIM: 616417) adhesion G protein-cou (1537)  616 90.3 4.4e-17
XP_016863421 (OMIM: 616417) PREDICTED: adhesion G  (1537)  616 90.3 4.4e-17
XP_011530090 (OMIM: 616417) PREDICTED: adhesion G  (1543)  616 90.3 4.4e-17
XP_016863420 (OMIM: 616417) PREDICTED: adhesion G  (1580)  616 90.3 4.5e-17
XP_016863418 (OMIM: 616417) PREDICTED: adhesion G  (1586)  616 90.3 4.5e-17
XP_016863419 (OMIM: 616417) PREDICTED: adhesion G  (1586)  616 90.3 4.5e-17
XP_006717052 (OMIM: 615899) PREDICTED: olfactomedi ( 616)  605 88.7 5.4e-17
NP_872293 (OMIM: 615899) olfactomedin-like protein ( 652)  605 88.7 5.6e-17
NP_001284635 (OMIM: 607018) adhesion G protein-cou (1123)  583 86.1 5.8e-16
XP_016856287 (OMIM: 607018) PREDICTED: adhesion G  (1163)  583 86.1   6e-16
XP_016856286 (OMIM: 607018) PREDICTED: adhesion G  (1173)  583 86.1   6e-16
NP_001284634 (OMIM: 607018) adhesion G protein-cou (1177)  583 86.1   6e-16
XP_016856284 (OMIM: 607018) PREDICTED: adhesion G  (1181)  583 86.1 6.1e-16
XP_016856285 (OMIM: 607018) PREDICTED: adhesion G  (1186)  583 86.1 6.1e-16
XP_016856283 (OMIM: 607018) PREDICTED: adhesion G  (1191)  583 86.1 6.1e-16
XP_016856282 (OMIM: 607018) PREDICTED: adhesion G  (1225)  583 86.1 6.2e-16
NP_001284633 (OMIM: 607018) adhesion G protein-cou (1403)  583 86.2   7e-16
NP_036434 (OMIM: 607018) adhesion G protein-couple (1403)  583 86.2   7e-16
XP_016856281 (OMIM: 607018) PREDICTED: adhesion G  (1408)  583 86.2   7e-16
NP_001317574 (OMIM: 607018) adhesion G protein-cou (1416)  583 86.2   7e-16
XP_016856279 (OMIM: 607018) PREDICTED: adhesion G  (1421)  583 86.2 7.1e-16
XP_005270725 (OMIM: 607018) PREDICTED: adhesion G  (1446)  583 86.2 7.2e-16
XP_016856278 (OMIM: 607018) PREDICTED: adhesion G  (1446)  583 86.2 7.2e-16
XP_016856277 (OMIM: 607018) PREDICTED: adhesion G  (1451)  583 86.2 7.2e-16
XP_005270723 (OMIM: 607018) PREDICTED: adhesion G  (1459)  583 86.2 7.2e-16
XP_016856276 (OMIM: 607018) PREDICTED: adhesion G  (1459)  583 86.2 7.2e-16
XP_016856275 (OMIM: 607018) PREDICTED: adhesion G  (1463)  583 86.2 7.2e-16
XP_016856274 (OMIM: 607018) PREDICTED: adhesion G  (1463)  583 86.2 7.2e-16


>>NP_000252 (OMIM: 137750,601652) myocilin precursor [Ho  (504 aa)
 initn: 3319 init1: 3319 opt: 3319  Z-score: 2251.4  bits: 426.1 E(85289): 1.2e-118
Smith-Waterman score: 3319; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)

               10        20        30        40        50        60
pF1KB5 MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 YDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 IRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN
              430       440       450       460       470       480

              490       500    
pF1KB5 PLEKKLFAWDNLNMVTYDIKLSKM
       ::::::::::::::::::::::::
NP_000 PLEKKLFAWDNLNMVTYDIKLSKM
              490       500    

>>NP_001269541 (OMIM: 605366) noelin isoform 5 [Homo sap  (458 aa)
 initn: 751 init1: 464 opt: 757  Z-score: 530.2  bits: 107.5 E(85289): 8.6e-23
Smith-Waterman score: 760; 32.7% identity (65.6% similar) in 407 aa overlap (110-501:53-449)

      80        90       100       110       120       130         
pF1KB5 TQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELE
                                     ::.:. . . .   ::.  ........ .:
NP_001 RVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIE
             30        40        50        60        70        80  

     140       150       160       170       180       190         
pF1KB5 TAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGS
       .      :: . .:. .....  . .. .  :: .:..::  ..   .  :  : . :  
NP_001 VLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKM-DELRPLIPVL
             90       100       110       120       130        140 

     200       210       220       230                      240    
pF1KB5 REVSTWNLDTLAFQELKSELTEVPASRILKESPSGY---------------LRSGEGDTG
       .: ..    .: :.:  ..:: :     :.:  ..:               ::.     .
NP_001 EEYKADAKLVLQFKEEVQNLTSVLNE--LQEEIGAYDYDELQSRVSNLEERLRACMQKLA
             150       160         170       180       190         

          250       260       270       280       290       300    
pF1KB5 CGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLI
       ::.:. ...:.:..:. .   ..: :: ::    :  .. .: .:   .. : : ::  .
NP_001 CGKLTGISDPVTVKTSGS---RFGSWMTDP--LAPEGDNRVWYMDGYHNN-RFVREYKSM
     200       210          220         230       240        250   

          310       320       330       340       350       360    
pF1KB5 SQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAG
        .::.      : ::.:  .:: :::.::.::.  .:. .::..:.:::.   . .  ::
NP_001 VDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAG
           260       270       280       290       300       310   

          370       380       390       400       410       420    
pF1KB5 YHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQ
       :.... :.:::..:::: :::.:::..:.:..  : ::.:.:.: .:.  :::.:.  :.
NP_001 YNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKR
           320       330       340       350       360       370   

          430       440       450       460       470       480    
pF1KB5 SVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEK
       :...:::::::::....: :. . :..::.:...  . . :::.:.:.. ::.:::: ..
NP_001 SAGEAFIICGTLYVTNGY-SGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDR
           380       390        400       410       420       430  

          490       500          
pF1KB5 KLFAWDNLNMVTYDIKLSKM      
        :.::.: ... :.. :         
NP_001 ALYAWNNGHQILYNVTLFHVIRSDEL
            440       450        

>>NP_055094 (OMIM: 605366) noelin isoform 1 precursor [H  (467 aa)
 initn: 777 init1: 464 opt: 757  Z-score: 530.1  bits: 107.5 E(85289): 8.7e-23
Smith-Waterman score: 760; 32.7% identity (65.6% similar) in 407 aa overlap (110-501:62-458)

      80        90       100       110       120       130         
pF1KB5 TQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELE
                                     ::.:. . . .   ::.  ........ .:
NP_055 QVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIE
              40        50        60        70        80        90 

     140       150       160       170       180       190         
pF1KB5 TAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGS
       .      :: . .:. .....  . .. .  :: .:..::  ..   .  :  : . :  
NP_055 VLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKM-DELRPLIPVL
             100       110       120       130       140        150

     200       210       220       230                      240    
pF1KB5 REVSTWNLDTLAFQELKSELTEVPASRILKESPSGY---------------LRSGEGDTG
       .: ..    .: :.:  ..:: :     :.:  ..:               ::.     .
NP_055 EEYKADAKLVLQFKEEVQNLTSVLNE--LQEEIGAYDYDELQSRVSNLEERLRACMQKLA
              160       170         180       190       200        

          250       260       270       280       290       300    
pF1KB5 CGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLI
       ::.:. ...:.:..:. .   ..: :: ::    :  .. .: .:   .. : : ::  .
NP_055 CGKLTGISDPVTVKTSGS---RFGSWMTDP--LAPEGDNRVWYMDGYHNN-RFVREYKSM
      210       220          230         240       250        260  

          310       320       330       340       350       360    
pF1KB5 SQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAG
        .::.      : ::.:  .:: :::.::.::.  .:. .::..:.:::.   . .  ::
NP_055 VDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAG
            270       280       290       300       310       320  

          370       380       390       400       410       420    
pF1KB5 YHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQ
       :.... :.:::..:::: :::.:::..:.:..  : ::.:.:.: .:.  :::.:.  :.
NP_055 YNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKR
            330       340       350       360       370       380  

          430       440       450       460       470       480    
pF1KB5 SVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEK
       :...:::::::::....: :. . :..::.:...  . . :::.:.:.. ::.:::: ..
NP_055 SAGEAFIICGTLYVTNGY-SGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDR
            390       400        410       420       430       440 

          490       500          
pF1KB5 KLFAWDNLNMVTYDIKLSKM      
        :.::.: ... :.. :         
NP_055 ALYAWNNGHQILYNVTLFHVIRSDEL
             450       460       

>>NP_001269540 (OMIM: 605366) noelin isoform 4 precursor  (485 aa)
 initn: 751 init1: 464 opt: 757  Z-score: 529.8  bits: 107.5 E(85289): 9e-23
Smith-Waterman score: 760; 32.7% identity (65.6% similar) in 407 aa overlap (110-501:80-476)

      80        90       100       110       120       130         
pF1KB5 TQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELE
                                     ::.:. . . .   ::.  ........ .:
NP_001 GVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIE
      50        60        70        80        90       100         

     140       150       160       170       180       190         
pF1KB5 TAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGS
       .      :: . .:. .....  . .. .  :: .:..::  ..   .  :  : . :  
NP_001 VLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKM-DELRPLIPVL
     110       120       130       140       150        160        

     200       210       220       230                      240    
pF1KB5 REVSTWNLDTLAFQELKSELTEVPASRILKESPSGY---------------LRSGEGDTG
       .: ..    .: :.:  ..:: :     :.:  ..:               ::.     .
NP_001 EEYKADAKLVLQFKEEVQNLTSVLNE--LQEEIGAYDYDELQSRVSNLEERLRACMQKLA
      170       180       190         200       210       220      

          250       260       270       280       290       300    
pF1KB5 CGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLI
       ::.:. ...:.:..:. .   ..: :: ::    :  .. .: .:   .. : : ::  .
NP_001 CGKLTGISDPVTVKTSGS---RFGSWMTDP--LAPEGDNRVWYMDGYHNN-RFVREYKSM
        230       240          250         260       270        280

          310       320       330       340       350       360    
pF1KB5 SQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAG
        .::.      : ::.:  .:: :::.::.::.  .:. .::..:.:::.   . .  ::
NP_001 VDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAG
              290       300       310       320       330       340

          370       380       390       400       410       420    
pF1KB5 YHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQ
       :.... :.:::..:::: :::.:::..:.:..  : ::.:.:.: .:.  :::.:.  :.
NP_001 YNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKR
              350       360       370       380       390       400

          430       440       450       460       470       480    
pF1KB5 SVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEK
       :...:::::::::....: :. . :..::.:...  . . :::.:.:.. ::.:::: ..
NP_001 SAGEAFIICGTLYVTNGY-SGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDR
              410        420       430       440       450         

          490       500          
pF1KB5 KLFAWDNLNMVTYDIKLSKM      
        :.::.: ... :.. :         
NP_001 ALYAWNNGHQILYNVTLFHVIRSDEL
     460       470       480     

>>NP_477518 (OMIM: 607567) noelin-3 isoform 2 precursor   (458 aa)
 initn: 645 init1: 443 opt: 676  Z-score: 475.7  bits: 97.4 E(85289): 9.2e-20
Smith-Waterman score: 695; 31.5% identity (60.8% similar) in 467 aa overlap (40-501:38-448)

      10        20        30        40        50        60         
pF1KB5 SFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMS
                                     :.: .:::  :  :..:... :        
NP_477 LNLLLLSLFAGLDPSKTQISPKEGWQVYSSAQDPDGRCICT--VVAPEQNLC--------
        10        20        30        40          50               

      70        80          90       100        110        120     
pF1KB5 VIHNLQRDSSTQRLD--LEATKARLSSLESLLHQLTLD-QAARPQETQ-EGLQRELGTLR
            .::.....:   :: ..   .:.: :  .   : : .  .::: .::. ..  ..
NP_477 -----SRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIE
             60        70        80        90       100       110  

         130        140       150       160       170       180    
pF1KB5 RERDQLETQT-RELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ
        .:  : :.  .::.  ...::    :::. :          :. . . ..:.  :    
NP_477 DDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTD--------AKLITQFKEEIRNLS---
            120       130       140               150       160    

          190       200       210       220       230       240    
pF1KB5 CPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTG
                ::  : .:    .. .  ..::..        :.:  :    ::.      
NP_477 ---------AVLTGIQE----EIGAYDYEELHQ--------RVL--SLETRLRDCMKKLT
                          170       180                 190        

          250       260       270       280       290       300    
pF1KB5 CGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLI
       ::.:. .  :.:..:. :   ..:.:: ::  .    .. .: .:.  :. . : ::  :
NP_477 CGKLMKITGPVTVKTSGT---RFGAWMTDPLASE--KNNRVWYMDSY-TNNKIVREYKSI
      200       210          220         230       240        250  

          310       320       330       340       350       360    
pF1KB5 SQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAG
       ..:..:  :... ::    .:. :::.:::::.  .:  .:.: ..   : :.. .  ::
NP_477 ADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAG
            260       270       280       290       300       310  

          370       380       390       400       410       420    
pF1KB5 YHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQ
       .:. .::.:::..:::: .:: :::..:.:..  : ::.:.:: ..::. ..: :.  :.
NP_477 FHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKR
            320       330       340       350       360       370  

          430       440       450       460       470       480    
pF1KB5 SVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEK
       :....:.::::::...:. .. : : ..:.: :.  .   :::.:.: . ::.:::  ..
NP_477 SAGESFMICGTLYVTNSHLTG-AKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDR
            380       390        400       410       420       430 

          490       500           
pF1KB5 KLFAWDNLNMVTYDIKLSKM       
        :.::.: ..: ... :          
NP_477 ALYAWNNGHQVLFNVTLFHIIKTEDDT
             440       450        

>>NP_001275750 (OMIM: 607567) noelin-3 isoform 1 precurs  (478 aa)
 initn: 645 init1: 443 opt: 676  Z-score: 475.5  bits: 97.4 E(85289): 9.6e-20
Smith-Waterman score: 695; 31.5% identity (60.8% similar) in 467 aa overlap (40-501:58-468)

      10        20        30        40        50        60         
pF1KB5 SFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMS
                                     :.: .:::  :  :..:... :        
NP_001 SLVGLNTTRLSTPDTLTQISPKEGWQVYSSAQDPDGRCICT--VVAPEQNLC--------
        30        40        50        60          70               

      70        80          90       100        110        120     
pF1KB5 VIHNLQRDSSTQRLD--LEATKARLSSLESLLHQLTLD-QAARPQETQ-EGLQRELGTLR
            .::.....:   :: ..   .:.: :  .   : : .  .::: .::. ..  ..
NP_001 -----SRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIE
             80        90       100       110       120       130  

         130        140       150       160       170       180    
pF1KB5 RERDQLETQT-RELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ
        .:  : :.  .::.  ...::    :::. :          :. . . ..:.  :    
NP_001 DDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTD--------AKLITQFKEEIRNLS---
            140       150       160               170       180    

          190       200       210       220       230       240    
pF1KB5 CPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTG
                ::  : .:    .. .  ..::..        :.:  :    ::.      
NP_001 ---------AVLTGIQE----EIGAYDYEELHQ--------RVL--SLETRLRDCMKKLT
                          190       200                 210        

          250       260       270       280       290       300    
pF1KB5 CGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLI
       ::.:. .  :.:..:. :   ..:.:: ::  .    .. .: .:.  :. . : ::  :
NP_001 CGKLMKITGPVTVKTSGT---RFGAWMTDPLASE--KNNRVWYMDSY-TNNKIVREYKSI
      220       230          240         250       260        270  

          310       320       330       340       350       360    
pF1KB5 SQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAG
       ..:..:  :... ::    .:. :::.:::::.  .:  .:.: ..   : :.. .  ::
NP_001 ADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAG
            280       290       300       310       320       330  

          370       380       390       400       410       420    
pF1KB5 YHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQ
       .:. .::.:::..:::: .:: :::..:.:..  : ::.:.:: ..::. ..: :.  :.
NP_001 FHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKR
            340       350       360       370       380       390  

          430       440       450       460       470       480    
pF1KB5 SVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEK
       :....:.::::::...:. .. : : ..:.: :.  .   :::.:.: . ::.:::  ..
NP_001 SAGESFMICGTLYVTNSHLTG-AKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDR
            400       410        420       430       440       450 

          490       500           
pF1KB5 KLFAWDNLNMVTYDIKLSKM       
        :.::.: ..: ... :          
NP_001 ALYAWNNGHQVLFNVTLFHIIKTEDDT
             460       470        

>>NP_001275752 (OMIM: 607567) noelin-3 isoform 3 [Homo s  (383 aa)
 initn: 645 init1: 443 opt: 673  Z-score: 474.9  bits: 97.0 E(85289): 1e-19
Smith-Waterman score: 687; 31.4% identity (64.2% similar) in 388 aa overlap (120-501:6-373)

      90       100       110       120            130       140    
pF1KB5 ARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERD-----QLETQTRELETAYSN
                                     :. .:: .::     ..::: . :.. . .
NP_001                          MSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQ
                                        10        20        30     

          150       160       170       180       190       200    
pF1KB5 LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVST
       .  :...:      . .. ..: ....     .  :.     : .  :. .   ..:. .
NP_001 IEDDRKTL------MTKHFQELKEKMDELLPLIPVLE-----QYKTDAKLITQFKEEIRN
          40              50        60             70        80    

          210        220       230       240       250       260   
pF1KB5 WNLDTLAFQE-LKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETI
        .    ..:: . .   :   .:.:  :    ::.      ::.:. .  :.:..:. : 
NP_001 LSAVLTGIQEEIGAYDYEELHQRVL--SLETRLRDCMKKLTCGKLMKITGPVTVKTSGT-
           90       100         110       120       130       140  

           270       280       290       300       310       320   
pF1KB5 TGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLE
         ..:.:: ::  .    .. .: .:.  :. . : ::  :..:..:  :... ::    
NP_001 --RFGAWMTDPLASE--KNNRVWYMDSY-TNNKIVREYKSIADFVSGAESRTYNLPFKWA
               150         160        170       180       190      

           330       340       350       360       370       380   
pF1KB5 STGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAV
       .:. :::.:::::.  .:  .:.: ..   : :.. .  ::.:. .::.:::..:::: .
NP_001 GTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMA
        200       210       220       230       240       250      

           390       400       410       420       430       440   
pF1KB5 DEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYT
       :: :::..:.:..  : ::.:.:: ..::. ..: :.  :.:....:.::::::...:. 
NP_001 DEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHL
        260       270       280       290       300       310      

           450       460       470       480       490       500   
pF1KB5 SADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSK
       .. : : ..:.: :.  .   :::.:.: . ::.:::  .. :.::.: ..: ... :  
NP_001 TG-AKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFH
         320       330       340       350       360       370     

               
pF1KB5 M       
               
NP_001 IIKTEDDT
         380   

>>XP_016855729 (OMIM: 607567) PREDICTED: noelin-3 isofor  (383 aa)
 initn: 645 init1: 443 opt: 673  Z-score: 474.9  bits: 97.0 E(85289): 1e-19
Smith-Waterman score: 687; 31.4% identity (64.2% similar) in 388 aa overlap (120-501:6-373)

      90       100       110       120            130       140    
pF1KB5 ARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERD-----QLETQTRELETAYSN
                                     :. .:: .::     ..::: . :.. . .
XP_016                          MSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQ
                                        10        20        30     

          150       160       170       180       190       200    
pF1KB5 LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVST
       .  :...:      . .. ..: ....     .  :.     : .  :. .   ..:. .
XP_016 IEDDRKTL------MTKHFQELKEKMDELLPLIPVLE-----QYKTDAKLITQFKEEIRN
          40              50        60             70        80    

          210        220       230       240       250       260   
pF1KB5 WNLDTLAFQE-LKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETI
        .    ..:: . .   :   .:.:  :    ::.      ::.:. .  :.:..:. : 
XP_016 LSAVLTGIQEEIGAYDYEELHQRVL--SLETRLRDCMKKLTCGKLMKITGPVTVKTSGT-
           90       100         110       120       130       140  

           270       280       290       300       310       320   
pF1KB5 TGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLE
         ..:.:: ::  .    .. .: .:.  :. . : ::  :..:..:  :... ::    
XP_016 --RFGAWMTDPLASE--KNNRVWYMDSY-TNNKIVREYKSIADFVSGAESRTYNLPFKWA
               150         160        170       180       190      

           330       340       350       360       370       380   
pF1KB5 STGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAV
       .:. :::.:::::.  .:  .:.: ..   : :.. .  ::.:. .::.:::..:::: .
XP_016 GTNHVVYNGSLYFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMA
        200       210       220       230       240       250      

           390       400       410       420       430       440   
pF1KB5 DEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYT
       :: :::..:.:..  : ::.:.:: ..::. ..: :.  :.:....:.::::::...:. 
XP_016 DEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHL
        260       270       280       290       300       310      

           450       460       470       480       490       500   
pF1KB5 SADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSK
       .. : : ..:.: :.  .   :::.:.: . ::.:::  .. :.::.: ..: ... :  
XP_016 TG-AKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFH
         320       330       340       350       360       370     

               
pF1KB5 M       
               
XP_016 IIKTEDDT
         380   

>>XP_016863431 (OMIM: 616417) PREDICTED: adhesion G prot  (1235 aa)
 initn: 576 init1: 469 opt: 616  Z-score: 429.1  bits: 90.2 E(85289): 3.7e-17
Smith-Waterman score: 616; 39.0% identity (69.5% similar) in 246 aa overlap (268-504:156-394)

       240       250       260       270          280       290    
pF1KB5 SGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDP---KPTYPYTQETTWRIDTVGTD
                                     :.: .::   .    :   : .: ::.   
XP_016 YKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLT--
         130       140       150       160       170       180     

          300       310       320       330       340       350    
pF1KB5 VRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETV
            ::.  ..:. : :. .. ::. ...:: :::.:.:.:.  ..:......: :.  
XP_016 -----EYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIK
                190       200       210       220       230        

          360       370       380       390       400       410    
pF1KB5 KAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELE
       ..:  : .:.::   :: ::: .:::::::: ::::::.:.. .: ::.:.::: .:..:
XP_016 SGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIE
      240       250       260       270       280       290        

          420       430       440             450       460        
pF1KB5 QTWETNIRKQSVANAFIICGTLYTVSS-YTSAD--AT---VNFAYDTGTGISKTLTIPFK
        ::.:   :.:..:::.::: ::.:.: : . :  ::   ... :.:  . .. . .:: 
XP_016 GTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFP
      300       310       320       330       340       350        

      470       480       490       500                            
pF1KB5 NRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM                        
       : :.: . .:::: .. :..:.: ..: :.. .. .                        
XP_016 NSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSE
      360       370       380       390       400       410        

XP_016 LERPSVKGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTH
      420       430       440       450       460       470        

>>NP_001309175 (OMIM: 616417) adhesion G protein-coupled  (1240 aa)
 initn: 576 init1: 469 opt: 616  Z-score: 429.1  bits: 90.2 E(85289): 3.7e-17
Smith-Waterman score: 616; 39.0% identity (69.5% similar) in 246 aa overlap (268-504:156-394)

       240       250       260       270          280       290    
pF1KB5 SGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDP---KPTYPYTQETTWRIDTVGTD
                                     :.: .::   .    :   : .: ::.   
NP_001 YKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLT--
         130       140       150       160       170       180     

          300       310       320       330       340       350    
pF1KB5 VRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETV
            ::.  ..:. : :. .. ::. ...:: :::.:.:.:.  ..:......: :.  
NP_001 -----EYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIK
                190       200       210       220       230        

          360       370       380       390       400       410    
pF1KB5 KAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELE
       ..:  : .:.::   :: ::: .:::::::: ::::::.:.. .: ::.:.::: .:..:
NP_001 SGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIE
      240       250       260       270       280       290        

          420       430       440             450       460        
pF1KB5 QTWETNIRKQSVANAFIICGTLYTVSS-YTSAD--AT---VNFAYDTGTGISKTLTIPFK
        ::.:   :.:..:::.::: ::.:.: : . :  ::   ... :.:  . .. . .:: 
NP_001 GTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFP
      300       310       320       330       340       350        

      470       480       490       500                            
pF1KB5 NRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM                        
       : :.: . .:::: .. :..:.: ..: :.. .. .                        
NP_001 NSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSE
      360       370       380       390       400       410        

NP_001 LERPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLD
      420       430       440       450       460       470        




504 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:31:15 2016 done: Sat Nov  5 15:31:16 2016
 Total Scan time:  9.080 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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