Result of FASTA (omim) for pF1KB6611
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6611, 412 aa
  1>>>pF1KB6611 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8462+/-0.000365; mu= 20.4479+/- 0.023
 mean_var=82.0725+/-16.085, 0's: 0 Z-trim(115.1): 241  B-trim: 66 in 1/53
 Lambda= 0.141571
 statistics sampled from 25008 (25266) to 25008 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.296), width:  16
 Scan time:  7.160

The best scores are:                                      opt bits E(85289)
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 2894 600.9 1.9e-171
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 2870 596.0 5.7e-170
NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 1590 334.6 2.8e-91
XP_016872126 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 1398 295.3 1.6e-79
XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
XP_011517964 (OMIM: 606503) PREDICTED: histone-lys ( 350) 1398 295.3 1.6e-79
NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 1398 295.3 1.6e-79
XP_011517333 (OMIM: 607001,610253) PREDICTED: hist ( 488)  537 119.6 1.7e-26
XP_011517332 (OMIM: 607001,610253) PREDICTED: hist ( 559)  537 119.6 1.9e-26
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775)  537 119.8 2.4e-26
NP_001180355 (OMIM: 606503) histone-lysine N-methy ( 230)  530 117.8 2.8e-26
XP_011517335 (OMIM: 607001,610253) PREDICTED: hist (1246)  537 120.0 3.3e-26
XP_011517328 (OMIM: 607001,610253) PREDICTED: hist (1253)  537 120.0 3.3e-26
XP_016870626 (OMIM: 607001,610253) PREDICTED: hist (1260)  537 120.0 3.3e-26
XP_016870627 (OMIM: 607001,610253) PREDICTED: hist (1260)  537 120.0 3.3e-26
XP_016870625 (OMIM: 607001,610253) PREDICTED: hist (1265)  537 120.0 3.3e-26
XP_011517327 (OMIM: 607001,610253) PREDICTED: hist (1267)  537 120.0 3.3e-26
XP_005266167 (OMIM: 607001,610253) PREDICTED: hist (1267)  537 120.0 3.3e-26
XP_011517326 (OMIM: 607001,610253) PREDICTED: hist (1275)  537 120.0 3.3e-26
XP_016870624 (OMIM: 607001,610253) PREDICTED: hist (1291)  537 120.0 3.4e-26
XP_006717351 (OMIM: 607001,610253) PREDICTED: hist (1292)  537 120.0 3.4e-26
XP_016870623 (OMIM: 607001,610253) PREDICTED: hist (1293)  537 120.0 3.4e-26
XP_011517325 (OMIM: 607001,610253) PREDICTED: hist (1294)  537 120.0 3.4e-26
XP_005266162 (OMIM: 607001,610253) PREDICTED: hist (1295)  537 120.0 3.4e-26
NP_079033 (OMIM: 607001,610253) histone-lysine N-m (1298)  537 120.0 3.4e-26
XP_011517324 (OMIM: 607001,610253) PREDICTED: hist (1300)  537 120.0 3.4e-26
XP_011517323 (OMIM: 607001,610253) PREDICTED: hist (1301)  537 120.0 3.4e-26
NP_001180356 (OMIM: 606503) histone-lysine N-methy ( 170)  526 116.9   4e-26
NP_001305762 (OMIM: 604599) histone-lysine N-methy (1008)  531 118.7 6.6e-26
NP_079532 (OMIM: 604599) histone-lysine N-methyltr (1176)  531 118.8 7.4e-26
XP_016865691 (OMIM: 604599) PREDICTED: histone-lys (1183)  531 118.8 7.4e-26
NP_006700 (OMIM: 604599) histone-lysine N-methyltr (1210)  531 118.8 7.5e-26
XP_006715039 (OMIM: 604599) PREDICTED: histone-lys (1217)  531 118.8 7.6e-26
NP_001276342 (OMIM: 604599) histone-lysine N-methy (1233)  531 118.8 7.6e-26
XP_006715038 (OMIM: 604599) PREDICTED: histone-lys (1240)  531 118.8 7.6e-26
XP_005248881 (OMIM: 604599) PREDICTED: histone-lys (1267)  531 118.8 7.8e-26
XP_006715037 (OMIM: 604599) PREDICTED: histone-lys (1274)  531 118.8 7.8e-26
NP_001263254 (OMIM: 609834) histone-lysine N-methy ( 365)  467 105.2 2.8e-22
NP_006506 (OMIM: 609834) histone-lysine N-methyltr ( 684)  467 105.4 4.4e-22
XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410)  347 80.7 7.4e-15
XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637)  347 80.9   1e-14
XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668)  347 80.9   1e-14
NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707)  347 80.9 1.1e-14
XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713)  347 80.9 1.1e-14
NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738)  347 81.0 1.1e-14
XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744)  347 81.0 1.1e-14
NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747)  347 81.0 1.1e-14
NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753)  347 81.0 1.1e-14
XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637)  334 78.2 6.3e-14


>>NP_003164 (OMIM: 300254) histone-lysine N-methyltransf  (412 aa)
 initn: 2894 init1: 2894 opt: 2894  Z-score: 3199.2  bits: 600.9 E(85289): 1.9e-171
Smith-Waterman score: 2894; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)

               10        20        30        40        50        60
pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
              310       320       330       340       350       360

              370       380       390       400       410  
pF1KB6 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
              370       380       390       400       410  

>>NP_001269095 (OMIM: 300254) histone-lysine N-methyltra  (423 aa)
 initn: 2870 init1: 2870 opt: 2870  Z-score: 3172.5  bits: 596.0 E(85289): 5.7e-170
Smith-Waterman score: 2870; 99.0% identity (99.5% similar) in 412 aa overlap (1-412:12-423)

                          10        20        30        40         
pF1KB6            MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC
                  .:. : :::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGMSRLRNDRLADPLTGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KB6 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KB6 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KB6 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
              190       200       210       220       230       240

     230       240       250       260       270       280         
pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
              370       380       390       400       410       420

     410  
pF1KB6 YLF
       :::
NP_001 YLF
          

>>NP_001180353 (OMIM: 606503) histone-lysine N-methyltra  (410 aa)
 initn: 1620 init1: 925 opt: 1590  Z-score: 1759.8  bits: 334.6 E(85289): 2.8e-91
Smith-Waterman score: 1658; 59.3% identity (78.0% similar) in 410 aa overlap (8-411:13-409)

                    10        20        30        40        50     
pF1KB6      MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIR
                   : : :  : . ::.:::  ::.: ..::.:::: ..::::::::: ..
NP_001 MAAVGAEARGAWC-VPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVK
               10         20        30        40        50         

          60        70        80        90        100           110
pF1KB6 EQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLR-RHHRSKTPRH----L
       ..:::::::.:.::: .:::: :::::  .:.:: .: .  : . .. .. ::.     :
NP_001 DMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTL
      60        70        80        90       100       110         

              120       130       140       150       160       170
pF1KB6 DPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGE
        :..:.:.:.::::: ::.::..::: ...: : : ::: :::.:::  : :::::. . 
NP_001 KPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAP
     120       130       140       150       160       170         

               180       190       200       210       220         
pF1KB6 GITL-NQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG
       ::.: :... :: : ::..     :::. .   .::: . :...  : :::::::::.::
NP_001 GISLVNEATFGCSCTDCFFQK---CCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCG
     180       190       200          210       220       230      

     230       240       250       260       270       280         
pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI
        :::::.:::: .:.::::::..::::::.:: ::.. :::::::::.:::::::::::.
NP_001 PDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQF
        240       250       260       270       280       290      

     290       300       310       320       330       340         
pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
       :: .: ::::::::  : .::::: :::.::::::::::::::.:::::::: ::::::.
NP_001 YDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIAL
        300       310       320       330       340       350      

     350       360       370       380       390       400         
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
       :.:::: :::::::::.:.    :. :  .: .      :.  :::::  ::::. .:: 
NP_001 FSTRTINAGEELTFDYQMK-GSGDISSDSIDHS------PA--KKRVRTVCKCGAVTCRG
        360       370        380             390         400       

     410  
pF1KB6 YLF
       :: 
NP_001 YLN
       410

>>XP_016872126 (OMIM: 606503) PREDICTED: histone-lysine   (350 aa)
 initn: 1429 init1: 925 opt: 1398  Z-score: 1548.7  bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)

        30        40        50        60        70        80       
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
                                     :::::::.:.::: .:::: :::::  .:.
XP_016                              MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
                                            10        20        30 

        90        100           110       120       130       140  
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
       :: .: .  : . .. .. ::.     : :..:.:.:.::::: ::.::..::: ...: 
XP_016 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
              40        50        60        70        80        90 

            150       160       170        180       190       200 
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
       : : ::: :::.:::  : :::::. . ::.: :... :: : ::..     :::. .  
XP_016 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
             100       110       120       130       140           

             210       220       230       240       250       260 
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
        .::: . :...  : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_016 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
      150       160       170       180       190       200        

             270       280       290       300       310       320 
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
        ::.. :::::::::.:::::::::::.:: .: ::::::::  : .::::: :::.:::
XP_016 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
      210       220       230       240       250       260        

             330       340       350       360       370       380 
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
       :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. .  :. :  .: 
XP_016 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
      270       280       290       300       310        320       

             390       400       410  
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       .      :.  :::::  ::::. .:: :: 
XP_016 S------PA--KKRVRTVCKCGAVTCRGYLN
             330         340       350

>>NP_001180354 (OMIM: 606503) histone-lysine N-methyltra  (350 aa)
 initn: 1429 init1: 925 opt: 1398  Z-score: 1548.7  bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)

        30        40        50        60        70        80       
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
                                     :::::::.:.::: .:::: :::::  .:.
NP_001                              MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
                                            10        20        30 

        90        100           110       120       130       140  
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
       :: .: .  : . .. .. ::.     : :..:.:.:.::::: ::.::..::: ...: 
NP_001 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
              40        50        60        70        80        90 

            150       160       170        180       190       200 
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
       : : ::: :::.:::  : :::::. . ::.: :... :: : ::..     :::. .  
NP_001 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
             100       110       120       130       140           

             210       220       230       240       250       260 
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
        .::: . :...  : :::::::::.:: :::::.:::: .:.::::::..::::::.::
NP_001 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
      150       160       170       180       190       200        

             270       280       290       300       310       320 
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
        ::.. :::::::::.:::::::::::.:: .: ::::::::  : .::::: :::.:::
NP_001 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
      210       220       230       240       250       260        

             330       340       350       360       370       380 
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
       :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. .  :. :  .: 
NP_001 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
      270       280       290       300       310        320       

             390       400       410  
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       .      :.  :::::  ::::. .:: :: 
NP_001 S------PA--KKRVRTVCKCGAVTCRGYLN
             330         340       350

>>XP_006717566 (OMIM: 606503) PREDICTED: histone-lysine   (350 aa)
 initn: 1429 init1: 925 opt: 1398  Z-score: 1548.7  bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)

        30        40        50        60        70        80       
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
                                     :::::::.:.::: .:::: :::::  .:.
XP_006                              MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
                                            10        20        30 

        90        100           110       120       130       140  
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
       :: .: .  : . .. .. ::.     : :..:.:.:.::::: ::.::..::: ...: 
XP_006 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
              40        50        60        70        80        90 

            150       160       170        180       190       200 
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
       : : ::: :::.:::  : :::::. . ::.: :... :: : ::..     :::. .  
XP_006 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
             100       110       120       130       140           

             210       220       230       240       250       260 
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
        .::: . :...  : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_006 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
      150       160       170       180       190       200        

             270       280       290       300       310       320 
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
        ::.. :::::::::.:::::::::::.:: .: ::::::::  : .::::: :::.:::
XP_006 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
      210       220       230       240       250       260        

             330       340       350       360       370       380 
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
       :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. .  :. :  .: 
XP_006 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
      270       280       290       300       310        320       

             390       400       410  
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       .      :.  :::::  ::::. .:: :: 
XP_006 S------PA--KKRVRTVCKCGAVTCRGYLN
             330         340       350

>>XP_011517964 (OMIM: 606503) PREDICTED: histone-lysine   (350 aa)
 initn: 1429 init1: 925 opt: 1398  Z-score: 1548.7  bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)

        30        40        50        60        70        80       
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
                                     :::::::.:.::: .:::: :::::  .:.
XP_011                              MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
                                            10        20        30 

        90        100           110       120       130       140  
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
       :: .: .  : . .. .. ::.     : :..:.:.:.::::: ::.::..::: ...: 
XP_011 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
              40        50        60        70        80        90 

            150       160       170        180       190       200 
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
       : : ::: :::.:::  : :::::. . ::.: :... :: : ::..     :::. .  
XP_011 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
             100       110       120       130       140           

             210       220       230       240       250       260 
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
        .::: . :...  : :::::::::.:: :::::.:::: .:.::::::..::::::.::
XP_011 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
      150       160       170       180       190       200        

             270       280       290       300       310       320 
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
        ::.. :::::::::.:::::::::::.:: .: ::::::::  : .::::: :::.:::
XP_011 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
      210       220       230       240       250       260        

             330       340       350       360       370       380 
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
       :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. .  :. :  .: 
XP_011 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
      270       280       290       300       310        320       

             390       400       410  
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       .      :.  :::::  ::::. .:: :: 
XP_011 S------PA--KKRVRTVCKCGAVTCRGYLN
             330         340       350

>>NP_078946 (OMIM: 606503) histone-lysine N-methyltransf  (350 aa)
 initn: 1429 init1: 925 opt: 1398  Z-score: 1548.7  bits: 295.3 E(85289): 1.6e-79
Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349)

        30        40        50        60        70        80       
pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK
                                     :::::::.:.::: .:::: :::::  .:.
NP_078                              MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ
                                            10        20        30 

        90        100           110       120       130       140  
pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL
       :: .: .  : . .. .. ::.     : :..:.:.:.::::: ::.::..::: ...: 
NP_078 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK
              40        50        60        70        80        90 

            150       160       170        180       190       200 
pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH
       : : ::: :::.:::  : :::::. . ::.: :... :: : ::..     :::. .  
NP_078 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV
             100       110       120       130       140           

             210       220       230       240       250       260 
pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL
        .::: . :...  : :::::::::.:: :::::.:::: .:.::::::..::::::.::
NP_078 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL
      150       160       170       180       190       200        

             270       280       290       300       310       320 
pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF
        ::.. :::::::::.:::::::::::.:: .: ::::::::  : .::::: :::.:::
NP_078 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF
      210       220       230       240       250       260        

             330       340       350       360       370       380 
pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS
       :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. .  :. :  .: 
NP_078 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH
      270       280       290       300       310        320       

             390       400       410  
pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF
       .      :.  :::::  ::::. .:: :: 
NP_078 S------PA--KKRVRTVCKCGAVTCRGYLN
             330         340       350

>>XP_011517333 (OMIM: 607001,610253) PREDICTED: histone-  (488 aa)
 initn: 583 init1: 255 opt: 537  Z-score: 596.6  bits: 119.6 E(85289): 1.7e-26
Smith-Waterman score: 537; 41.2% identity (64.6% similar) in 226 aa overlap (149-365:217-432)

      120       130       140       150       160       170        
pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVA
                                     : :: .  :  . :...  :   .....  
XP_011 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI
        190       200       210       220       230       240      

      180           190       200       210           220       230
pF1KB6 VG---CEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV--RLRAGLP--IYECNSRCRCGY
       .    : : .::    ...:  :    .  :. .:..  ..  . :  :.:::  : :  
XP_011 THLQYCVCIDDC---SSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWR
        250          260       270       280       290       300   

              240       250       260       270       280       290
pF1KB6 DCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIY
       .: :::::.:.:  : ..:: :  :::::.:. :  ..:: :::::.:.. ::. : .  
XP_011 NCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE--
           310       320        330       340       350       360  

              300        310       320       330       340         
pF1KB6 DRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
       :    .::::::  . .:: .:: .:::.:.:.:: :.:::    ::. . : :.:::::
XP_011 D----SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAF
                  370       380       390       400       410      

     350       360       370       380       390       400         
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
       :.:: :.:::.: :::                                            
XP_011 FSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGL
        420       430       440       450       460       470      

>>XP_011517332 (OMIM: 607001,610253) PREDICTED: histone-  (559 aa)
 initn: 583 init1: 255 opt: 537  Z-score: 595.8  bits: 119.6 E(85289): 1.9e-26
Smith-Waterman score: 537; 41.2% identity (64.6% similar) in 226 aa overlap (149-365:288-503)

      120       130       140       150       160       170        
pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVA
                                     : :: .  :  . :...  :   .....  
XP_011 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI
       260       270       280       290       300       310       

      180           190       200       210           220       230
pF1KB6 VG---CEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV--RLRAGLP--IYECNSRCRCGY
       .    : : .::    ...:  :    .  :. .:..  ..  . :  :.:::  : :  
XP_011 THLQYCVCIDDC---SSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWR
       320          330       340       350       360       370    

              240       250       260       270       280       290
pF1KB6 DCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIY
       .: :::::.:.:  : ..:: :  :::::.:. :  ..:: :::::.:.. ::. : .  
XP_011 NCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE--
          380       390        400       410       420       430   

              300        310       320       330       340         
pF1KB6 DRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF
       :    .::::::  . .:: .:: .:::.:.:.:: :.:::    ::. . : :.:::::
XP_011 D----SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAF
                 440       450       460       470       480       

     350       360       370       380       390       400         
pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK
       :.:: :.:::.: :::                                            
XP_011 FSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGL
       490       500       510       520       530       540       




412 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:05:00 2016 done: Sat Nov  5 11:05:01 2016
 Total Scan time:  7.160 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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