Result of FASTA (omim) for pF1KE1305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1305, 1360 aa
  1>>>pF1KE1305 1360 - 1360 aa - 1360 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7175+/-0.000417; mu= 13.1214+/- 0.026
 mean_var=162.5707+/-33.262, 0's: 0 Z-trim(116.1): 52  B-trim: 337 in 2/54
 Lambda= 0.100590
 statistics sampled from 26940 (26990) to 26940 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.316), width:  16
 Scan time: 13.580

The best scores are:                                      opt bits E(85289)
NP_000170 (OMIM: 276300,600678,608089,614350) DNA  (1360) 9062 1328.4       0
XP_011531100 (OMIM: 276300,600678,608089,614350) P (1299) 8500 1246.8       0
XP_011531101 (OMIM: 276300,600678,608089,614350) P (1261) 8387 1230.4       0
NP_001268421 (OMIM: 276300,600678,608089,614350) D (1230) 7615 1118.4       0
NP_001268422 (OMIM: 276300,600678,608089,614350) D (1058) 7032 1033.7       0
NP_001268423 (OMIM: 276300,600678,608089,614350) D (1058) 7032 1033.7       0
NP_002430 (OMIM: 600887,608089,617100) DNA mismatc (1137)  601 100.5 7.4e-20
NP_001245210 (OMIM: 120435,158320,276300,609309) D ( 868)  590 98.8 1.8e-19
XP_011531169 (OMIM: 120435,158320,276300,609309) P ( 924)  590 98.8 1.9e-19
NP_000242 (OMIM: 120435,158320,276300,609309) DNA  ( 934)  590 98.8 1.9e-19
XP_005264389 (OMIM: 120435,158320,276300,609309) P ( 974)  590 98.8   2e-19
NP_002431 (OMIM: 602105) mutS protein homolog 4 [H ( 936)  408 72.4 1.7e-11
NP_002432 (OMIM: 603382) mutS protein homolog 5 is ( 834)  393 70.2 7.1e-11
NP_751898 (OMIM: 603382) mutS protein homolog 5 is ( 834)  393 70.2 7.1e-11
NP_751897 (OMIM: 603382) mutS protein homolog 5 is ( 835)  381 68.5 2.4e-10
NP_079535 (OMIM: 603382) mutS protein homolog 5 is ( 822)  334 61.6 2.7e-08
NP_015627 (OMIM: 194190,602952) histone-lysine N-m ( 629)  265 51.5 2.2e-05
XP_005248062 (OMIM: 194190,602952) PREDICTED: hist ( 647)  265 51.5 2.3e-05
NP_579889 (OMIM: 194190,602952) histone-lysine N-m ( 647)  265 51.5 2.3e-05
XP_006713977 (OMIM: 194190,602952) PREDICTED: hist ( 647)  265 51.5 2.3e-05
NP_060248 (OMIM: 607083) histone-lysine N-methyltr ( 645)  262 51.1 3.1e-05
XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296)  265 51.8 3.9e-05
NP_579890 (OMIM: 194190,602952) histone-lysine N-m (1365)  265 51.8 4.1e-05
XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365)  265 51.8 4.1e-05
XP_005248058 (OMIM: 194190,602952) PREDICTED: hist (1365)  265 51.8 4.1e-05
NP_579877 (OMIM: 194190,602952) histone-lysine N-m (1365)  265 51.8 4.1e-05
NP_001035889 (OMIM: 194190,602952) histone-lysine  (1365)  265 51.8 4.1e-05
NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365)  265 51.8 4.1e-05
NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437)  262 51.4 5.7e-05


>>NP_000170 (OMIM: 276300,600678,608089,614350) DNA mism  (1360 aa)
 initn: 9062 init1: 9062 opt: 9062  Z-score: 7112.3  bits: 1328.4 E(85289):    0
Smith-Waterman score: 9062; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)

               10        20        30        40        50        60
pF1KE1 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE1 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE1 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE1 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE1 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE1 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE1 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE1 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE1 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE1 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE1 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE1 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE1 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE1 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
       ::::::::::::::::::::::::::::::::::::::::
NP_000 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
             1330      1340      1350      1360

>>XP_011531100 (OMIM: 276300,600678,608089,614350) PREDI  (1299 aa)
 initn: 8483 init1: 8483 opt: 8500  Z-score: 6671.8  bits: 1246.8 E(85289):    0
Smith-Waterman score: 8500; 99.3% identity (99.5% similar) in 1286 aa overlap (75-1360:14-1299)

           50        60        70        80        90       100    
pF1KE1 GGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYP
                                     :.:. :   :   :::::::::::::::::
XP_011                  MPAGGRTGRVRWCGVRKEVPRPARRYCDFSPGDLVWAKMEGYP
                                10        20        30        40   

          110       120       130       140       150       160    
pF1KE1 WWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGH
            50        60        70        80        90       100   

          170       180       190       200       210       220    
pF1KE1 FYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNE
           110       120       130       140       150       160   

          230       240       250       260       270       280    
pF1KE1 IESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGD
           170       180       190       200       210       220   

          290       300       310       320       330       340    
pF1KE1 SESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQ
           230       240       250       260       270       280   

          350       360       370       380       390       400    
pF1KE1 NSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLN
           290       300       310       320       330       340   

          410       420       430       440       450       460    
pF1KE1 SCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEI
           350       360       370       380       390       400   

          470       480       490       500       510       520    
pF1KE1 AFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTY
           410       420       430       440       450       460   

          530       540       550       560       570       580    
pF1KE1 SVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRT
           470       480       490       500       510       520   

          590       600       610       620       630       640    
pF1KE1 LVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFR
           530       540       550       560       570       580   

          650       660       670       680       690       700    
pF1KE1 EKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMA
           590       600       610       620       630       640   

          710       720       730       740       750       760    
pF1KE1 NFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDT
           650       660       670       680       690       700   

          770       780       790       800       810       820    
pF1KE1 CHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSK
           710       720       730       740       750       760   

          830       840       850       860       870       880    
pF1KE1 IHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKS
           770       780       790       800       810       820   

          890       900       910       920       930       940    
pF1KE1 KILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADI
           830       840       850       860       870       880   

          950       960       970       980       990      1000    
pF1KE1 RENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCK
           890       900       910       920       930       940   

         1010      1020      1030      1040      1050      1060    
pF1KE1 RYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLA
           950       960       970       980       990      1000   

         1070      1080      1090      1100      1110      1120    
pF1KE1 NYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQEN
          1010      1020      1030      1040      1050      1060   

         1130      1140      1150      1160      1170      1180    
pF1KE1 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM
          1070      1080      1090      1100      1110      1120   

         1190      1200      1210      1220      1230      1240    
pF1KE1 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL
          1130      1140      1150      1160      1170      1180   

         1250      1260      1270      1280      1290      1300    
pF1KE1 FSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAAR
          1190      1200      1210      1220      1230      1240   

         1310      1320      1330      1340      1350      1360
pF1KE1 LANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
          1250      1260      1270      1280      1290         

>>XP_011531101 (OMIM: 276300,600678,608089,614350) PREDI  (1261 aa)
 initn: 8387 init1: 8387 opt: 8387  Z-score: 6583.3  bits: 1230.4 E(85289):    0
Smith-Waterman score: 8387; 100.0% identity (100.0% similar) in 1261 aa overlap (100-1360:1-1261)

      70        80        90       100       110       120         
pF1KE1 KNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRV
                                     ::::::::::::::::::::::::::::::
XP_011                               MEGYPWWPCLVYNHPFDGTFIREKGKSVRV
                                             10        20        30

     130       140       150       160       170       180         
pF1KE1 HVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIK
               40        50        60        70        80        90

     190       200       210       220       230       240         
pF1KE1 RLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRR
              100       110       120       130       140       150

     250       260       270       280       290       300         
pF1KE1 VISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGS
              160       170       180       190       200       210

     310       320       330       340       350       360         
pF1KE1 LKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHET
              220       230       240       250       260       270

     370       380       390       400       410       420         
pF1KE1 LEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKV
              280       290       300       310       320       330

     430       440       450       460       470       480         
pF1KE1 GKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETP
              340       350       360       370       380       390

     490       500       510       520       530       540         
pF1KE1 EMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDS
              400       410       420       430       440       450

     550       560       570       580       590       600         
pF1KE1 SGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTIL
              460       470       480       490       500       510

     610       620       630       640       650       660         
pF1KE1 KSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSI
              520       530       540       550       560       570

     670       680       690       700       710       720         
pF1KE1 GLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKA
              580       590       600       610       620       630

     730       740       750       760       770       780         
pF1KE1 YQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAIN
              640       650       660       670       680       690

     790       800       810       820       830       840         
pF1KE1 DRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETT
              700       710       720       730       740       750

     850       860       870       880       890       900         
pF1KE1 YSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVEL
              760       770       780       790       800       810

     910       920       930       940       950       960         
pF1KE1 NRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVY
              820       830       840       850       860       870

     970       980       990      1000      1010      1020         
pF1KE1 WGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSL
              880       890       900       910       920       930

    1030      1040      1050      1060      1070      1080         
pF1KE1 KDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFL
              940       950       960       970       980       990

    1090      1100      1110      1120      1130      1140         
pF1KE1 ELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGL
             1000      1010      1020      1030      1040      1050

    1150      1160      1170      1180      1190      1200         
pF1KE1 LAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSL
             1060      1070      1080      1090      1100      1110

    1210      1220      1230      1240      1250      1260         
pF1KE1 VLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMAC
             1120      1130      1140      1150      1160      1170

    1270      1280      1290      1300      1310      1320         
pF1KE1 MVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQS
             1180      1190      1200      1210      1220      1230

    1330      1340      1350      1360
pF1KE1 LRLFREVCLASERSTVDAEAVHKLLTLIKEL
       :::::::::::::::::::::::::::::::
XP_011 LRLFREVCLASERSTVDAEAVHKLLTLIKEL
             1240      1250      1260 

>>NP_001268421 (OMIM: 276300,600678,608089,614350) DNA m  (1230 aa)
 initn: 7615 init1: 7615 opt: 7615  Z-score: 5978.0  bits: 1118.4 E(85289):    0
Smith-Waterman score: 7874; 90.4% identity (90.4% similar) in 1360 aa overlap (1-1360:1-1230)

               10        20        30        40        50        60
pF1KE1 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
       ::::::::::::::::::::                                        
NP_001 ARSASPPKAKNLNGGLRRSV----------------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KE1 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KE1 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
                                     ::::::::::::::::::::::::::::::
NP_001 ------------------------------GTTYVTDKSEEDNEIESEEEVQPKTQGSRR
                                             90       100       110

              250       260       270       280       290       300
pF1KE1 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
              120       130       140       150       160       170

              310       320       330       340       350       360
pF1KE1 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
              180       190       200       210       220       230

              370       380       390       400       410       420
pF1KE1 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
              240       250       260       270       280       290

              430       440       450       460       470       480
pF1KE1 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
              300       310       320       330       340       350

              490       500       510       520       530       540
pF1KE1 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
              360       370       380       390       400       410

              550       560       570       580       590       600
pF1KE1 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
              420       430       440       450       460       470

              610       620       630       640       650       660
pF1KE1 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
              480       490       500       510       520       530

              670       680       690       700       710       720
pF1KE1 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
              540       550       560       570       580       590

              730       740       750       760       770       780
pF1KE1 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
              600       610       620       630       640       650

              790       800       810       820       830       840
pF1KE1 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
              660       670       680       690       700       710

              850       860       870       880       890       900
pF1KE1 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
              720       730       740       750       760       770

              910       920       930       940       950       960
pF1KE1 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
              780       790       800       810       820       830

              970       980       990      1000      1010      1020
pF1KE1 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
              840       850       860       870       880       890

             1030      1040      1050      1060      1070      1080
pF1KE1 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
              900       910       920       930       940       950

             1090      1100      1110      1120      1130      1140
pF1KE1 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
              960       970       980       990      1000      1010

             1150      1160      1170      1180      1190      1200
pF1KE1 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
             1020      1030      1040      1050      1060      1070

             1210      1220      1230      1240      1250      1260
pF1KE1 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
             1080      1090      1100      1110      1120      1130

             1270      1280      1290      1300      1310      1320
pF1KE1 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
             1140      1150      1160      1170      1180      1190

             1330      1340      1350      1360
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
       ::::::::::::::::::::::::::::::::::::::::
NP_001 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
             1200      1210      1220      1230

>>NP_001268422 (OMIM: 276300,600678,608089,614350) DNA m  (1058 aa)
 initn: 7032 init1: 7032 opt: 7032  Z-score: 5521.7  bits: 1033.7 E(85289):    0
Smith-Waterman score: 7032; 100.0% identity (100.0% similar) in 1058 aa overlap (303-1360:1-1058)

            280       290       300       310       320       330  
pF1KE1 GSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSE
                                     ::::::::::::::::::::::::::::::
NP_001                               MVTGNGSLKRKSSRKETPSATKQATSISSE
                                             10        20        30

            340       350       360       370       380       390  
pF1KE1 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
               40        50        60        70        80        90

            400       410       420       430       440       450  
pF1KE1 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
              100       110       120       130       140       150

            460       470       480       490       500       510  
pF1KE1 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
              160       170       180       190       200       210

            520       530       540       550       560       570  
pF1KE1 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
              220       230       240       250       260       270

            580       590       600       610       620       630  
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
              280       290       300       310       320       330

            640       650       660       670       680       690  
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
              340       350       360       370       380       390

            700       710       720       730       740       750  
pF1KE1 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
              400       410       420       430       440       450

            760       770       780       790       800       810  
pF1KE1 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
              460       470       480       490       500       510

            820       830       840       850       860       870  
pF1KE1 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
              520       530       540       550       560       570

            880       890       900       910       920       930  
pF1KE1 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
              580       590       600       610       620       630

            940       950       960       970       980       990  
pF1KE1 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
              640       650       660       670       680       690

           1000      1010      1020      1030      1040      1050  
pF1KE1 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
              700       710       720       730       740       750

           1060      1070      1080      1090      1100      1110  
pF1KE1 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
              760       770       780       790       800       810

           1120      1130      1140      1150      1160      1170  
pF1KE1 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
              820       830       840       850       860       870

           1180      1190      1200      1210      1220      1230  
pF1KE1 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
              880       890       900       910       920       930

           1240      1250      1260      1270      1280      1290  
pF1KE1 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
              940       950       960       970       980       990

           1300      1310      1320      1330      1340      1350  
pF1KE1 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
             1000      1010      1020      1030      1040      1050

           1360
pF1KE1 LLTLIKEL
       ::::::::
NP_001 LLTLIKEL
               

>>NP_001268423 (OMIM: 276300,600678,608089,614350) DNA m  (1058 aa)
 initn: 7032 init1: 7032 opt: 7032  Z-score: 5521.7  bits: 1033.7 E(85289):    0
Smith-Waterman score: 7032; 100.0% identity (100.0% similar) in 1058 aa overlap (303-1360:1-1058)

            280       290       300       310       320       330  
pF1KE1 GSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSE
                                     ::::::::::::::::::::::::::::::
NP_001                               MVTGNGSLKRKSSRKETPSATKQATSISSE
                                             10        20        30

            340       350       360       370       380       390  
pF1KE1 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
               40        50        60        70        80        90

            400       410       420       430       440       450  
pF1KE1 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
              100       110       120       130       140       150

            460       470       480       490       500       510  
pF1KE1 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
              160       170       180       190       200       210

            520       530       540       550       560       570  
pF1KE1 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
              220       230       240       250       260       270

            580       590       600       610       620       630  
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
              280       290       300       310       320       330

            640       650       660       670       680       690  
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
              340       350       360       370       380       390

            700       710       720       730       740       750  
pF1KE1 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
              400       410       420       430       440       450

            760       770       780       790       800       810  
pF1KE1 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
              460       470       480       490       500       510

            820       830       840       850       860       870  
pF1KE1 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
              520       530       540       550       560       570

            880       890       900       910       920       930  
pF1KE1 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
              580       590       600       610       620       630

            940       950       960       970       980       990  
pF1KE1 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
              640       650       660       670       680       690

           1000      1010      1020      1030      1040      1050  
pF1KE1 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
              700       710       720       730       740       750

           1060      1070      1080      1090      1100      1110  
pF1KE1 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
              760       770       780       790       800       810

           1120      1130      1140      1150      1160      1170  
pF1KE1 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
              820       830       840       850       860       870

           1180      1190      1200      1210      1220      1230  
pF1KE1 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
              880       890       900       910       920       930

           1240      1250      1260      1270      1280      1290  
pF1KE1 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
              940       950       960       970       980       990

           1300      1310      1320      1330      1340      1350  
pF1KE1 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
             1000      1010      1020      1030      1040      1050

           1360
pF1KE1 LLTLIKEL
       ::::::::
NP_001 LLTLIKEL
               

>>NP_002430 (OMIM: 600887,608089,617100) DNA mismatch re  (1137 aa)
 initn: 816 init1: 427 opt: 601  Z-score: 477.5  bits: 100.5 E(85289): 7.4e-20
Smith-Waterman score: 1053; 26.9% identity (58.9% similar) in 1121 aa overlap (248-1331:85-1101)

       220       230       240       250       260       270       
pF1KE1 KSEEDNEIESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDE
                                     ::     :.: :    . :   ..::.:: 
NP_002 AAAAAAAAPPAPPAPAFPPQLPPHIATEIDRRKKRPLEND-GPVKKKVKKVQQKEGGSDL
           60        70        80        90        100       110   

       280       290       300       310       320       330       
pF1KE1 ISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTL
         ::  .::      : :  : :. .  .  .::.    .  :..  :. :.. .     
NP_002 GMSG--NSE------PKKCLRTRN-VSKSLEKLKEFCCDSALPQSRVQTESLQERFAVLP
             120              130       140       150       160    

       340       350       360       370       380       390       
pF1KE1 RAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLY
       .  .  . :  .:. . ...::.:       ::  :..    .      .: ... ..  
NP_002 KCTDFDDISLLHAKNAVSSEDSKRQINQKDTTLFDLSQFGSSNT-----SHENLQKTASK
          170       180       190       200            210         

       400        410       420       430       440       450      
pF1KE1 VPEDFLNSC-TPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLV-FMKGN
         .   .:  ::   .. ..:.:. : :.: . :  :...  :: :.. ::..   .  :
NP_002 SANKRSKSIYTPLELQYIEMKQQHKDAVLCVECGYKYRFFGEDAEIAARELNIYCHLDHN
     220       230       240       250       260       270         

         460       470       480       490              500        
pF1KE1 WAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMM---EARC----RKMAHISKYDRV
       .  ...:   .  .   :: :::::. :.::::  .    . :     ::.. .   . .
NP_002 FMTASIPTHRLFVHVRRLVAKGYKVGVVKQTETAALKAIGDNRSSLFSRKLTALYTKSTL
     280       290       300       310       320       330         

      510       520       530       540       550          560     
pF1KE1 VRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRA---YGVCFVDTSL
       . ...  .: :  .. .: :   ... ..::: ..:..:.   . ..    :.  :. . 
NP_002 IGEDVNPLI-KLDDAVNVDEI-MTDTSTSYLLCISENKENVRDKKKGNIFIGIVGVQPAT
     340        350        360       370       380       390       

         570       580       590       600       610       620     
pF1KE1 GKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIP--
       :.  . .:.:.   :...: ..   ::..:. .. ::..:..... . : :.:.  :   
NP_002 GEVVFDSFQDSASRSELETRMSSLQPVELLLPSA-LSEQTEALIHRATSVSVQDDRIRVE
       400       410       420       430        440       450      

             630       640       650       660       670       680 
pF1KE1 --GSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELAL
          . ... :...... :   :  :  : . .   :...:.      ..:   ::   ..
NP_002 RMDNIYFEYSHAFQAVTE---FYAK--DTVDIKGSQIISGI------VNL---EKP--VI
        460       470            480       490                  500

             690       700       710       720       730       740 
pF1KE1 SALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLN
        .:.. . :::.  ... : .  ::..                 ... .. :.....:: 
NP_002 CSLAAIIKYLKEFNLEKMLSKPENFKQ-----------------LSSKMEFMTINGTTLR
              510       520                        530       540   

             750       760       770       780       790       800 
pF1KE1 NLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVV
       ::::. : :. .:.:.::  .:  .: ::.: ::.:.  :: .   :: ::::. ...  
NP_002 NLEILQNQTDMKTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHS
           550       560       570       580       590       600   

              810       820       830       840       850       860
pF1KE1 PDKI-SEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLS
        ... ... . :.::::.:: : .:..  .  ..:.      ..  .: :  :.  .: .
NP_002 ESSVFGQIENHLRKLPDIERGLCSIYH--KKCSTQEF-----FLIVKTLYHLKS--EFQA
           610       620       630              640       650      

              870       880       890       900       910       920
pF1KE1 ALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEK
                    :.  : . ..: .:. :: :.       .:.:   ....   .. :.
NP_002 -------------IIPAVNSHIQSDLLRTVI-LE-------IPELLSPVEHYLKILN-EQ
                       660       670               680       690   

              930       940        950           960       970     
pF1KE1 ARKTGLITPKAGFDSDYDQALADIRENE-QSLLE----YLEKQRNRIGCRTIVYWGIGRN
       : :.:  :    : .  :  :   :..: :....    .:.. :. .   .  :  .. .
NP_002 AAKVGDKTEL--FKDLSDFPLIKKRKDEIQGVIDEIRMHLQEIRKILKNPSAQYVTVSGQ
            700         710       720       730       740       750

         980       990      1000      1010      1020      1030     
pF1KE1 RYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRR
       ....:: .: ..  .: ..   .. :. .:. .  :   . :  . .. :.  . ::  .
NP_002 EFMIEI-KNSAVSCIPTDWVKVGSTKAVSRFHSPFI---VENYRHLNQLREQLVLDCSAE
               760       770       780          790       800      

           1040      1050      1060      1070      1080      1090  
pF1KE1 ---LFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELK
          .. .:...:..  .::. .:..: .. ::. .. ::  .:::..   :.    . .:
NP_002 WLDFLEKFSEHYHSLCKAVHHLATVDCIFSLAKVAKQGD--YCRPTV--QEERK--IVIK
        810       820       830       840         850           860

           1100        1110      1120      1130      1140      1150
pF1KE1 GSRHPCITKTFFG--DDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLL
       ..::: :  ...:  :...::.  .. :. :.       ...:::::::::. ..:..:.
NP_002 NGRHPVID-VLLGEQDQYVPNNTDLS-EDSER------VMIITGPNMGGKSSYIKQVALI
               870       880        890             900       910  

             1160      1170      1180      1190      1200      1210
pF1KE1 AVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLV
       ..:::.: :::::   .  .: .:::.::.: :..:.:::. ::..:: :. .::..:::
NP_002 TIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGQSTFMEELTDTAEIIRKATSQSLV
            920       930       940       950       960       970  

             1220      1230      1240      1250         1260       
pF1KE1 LVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVE---DYSQNVAVRLGHM
       ..:::::::.: :: ::: :... . . .:  ::: :::  . :   .::..:.    ::
NP_002 ILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKNYSHQVGNY--HM
            980       990      1000      1010      1020        1030

      1270        1280           1290      1300      1310      1320
pF1KE1 ACMV-ENECE-DPSQ-----ETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
       . .: :.: . ::.      . .::::.. .:   .:::.:.:.::..: :...:. .:.
NP_002 GFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIAARSYGLNVAKLADVPGEILKKAAHKS
             1040      1050      1060      1070      1080      1090

             1330      1340      1350      1360       
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL       
       .:.: . .. :                                    
NP_002 KELEGLINTKRKRLKYFAKLWTMHNAQDLQKWTEEFNMEETQTSLLH
             1100      1110      1120      1130       

>>NP_001245210 (OMIM: 120435,158320,276300,609309) DNA m  (868 aa)
 initn: 678 init1: 428 opt: 590  Z-score: 470.5  bits: 98.8 E(85289): 1.8e-19
Smith-Waterman score: 833; 27.8% identity (57.7% similar) in 823 aa overlap (521-1325:63-787)

              500       510       520       530       540       550
pF1KE1 MMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSS
                                     .:  ..: :. . . :  ....: .  :..
NP_001 RVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ
             40        50        60        70        80        90  

              560       570       580       590       600       610
pF1KE1 GHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILK
          :  :: .::.   :. . .: :. . : ...:. .  : . ..  :. . .      
NP_001 ---RQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----
               100       110       120       130       140         

              620       630       640       650       660       670
pF1KE1 SSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIG
       ..:   .:.: :  ..   :. . . . ..              : ..:::  .:. . .
NP_001 GKLRQIIQRGGILITERKKADFSTKDIYQD--------------LNRLLKGKKGEQMNSA
          150       160       170                     180       190

              680       690       700        710       720         
pF1KE1 LTPGEKSELALSALGGCVFYLKKCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKA
       . :  ....:.:.:.. . .:       ::::  .:: ..     :          :.  
NP_001 VLPEMENQVAVSSLSAVIKFL-------ELLSDDSNFGQFELTTFD----------FS--
              200       210              220                 230   

     730       740       750         760       770       780       
pF1KE1 YQRMVLDAVTLNNLEIFLNGTNGSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYA
        : : :: ...  :..: .:.  .: :.  :   .. :.:: :.::..::.  :: ..  
NP_001 -QYMKLDIAAVRALNLF-QGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNR
              240        250       260       270       280         

       790       800       810         820       830               
pF1KE1 INDRLDAIEDLMVVPDKISEVVE--LLKKLPDLERLLSKIHNVGSPLKS--------QNH
       :..::. .: . :   .. ....  ::...:::.:: .:..  .. :..        .. 
NP_001 IEERLNLVEAF-VEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQL
     290       300        310       320       330       340        

       840        850       860        870       880       890     
pF1KE1 PDS-RAIMYEETTYSKKKIIDFLSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQT
       :.  .:.  .:  ..:  .  :.. :  ..  . :.  ..: . :      . :: . . 
NP_001 PNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLD------MDQVENHEF
      350       360       370       380       390             400  

         900       910       920       930       940       950     
pF1KE1 KNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYL
           .  :.:. ::   .   : ::  .. ::.  :. :   : .  .:. . .. . : 
NP_001 LVKPSFDPNLS-ELR--EIMNDLEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYY
            410          420       430         440        450      

         960       970       980       990      1000      1010     
pF1KE1 EKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKL
            :. :.      . ::       .::.: ..      :.  :  .   :.  :.  
NP_001 F----RVTCKE---EKVLRNN------KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYT
            460          470                  480       490        

        1020      1030      1040       1050      1060      1070    
pF1KE1 ANLINAEERRDVSLKDCMRRLFYNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPM
        :  . :: .:. .:. .     :....: .  :.  . .: ::... .:. : :.  :.
NP_001 KNKTEYEEAQDAIVKEIV-----NISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPY
      500       510            520       530       540       550   

         1080      1090      1100        1110      1120      1130  
pF1KE1 CRPVILLPEDTPPFLELKGSRHPCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLV
        ::.::  :     . ::.::: :.      :.  :::::. .       :. : .  ..
NP_001 VRPAIL--EKGQGRIILKASRHACVE---VQDEIAFIPNDVYF-------EKDKQMFHII
             560       570          580       590              600 

           1140      1150      1160      1170      1180      1190  
pF1KE1 TGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFV
       :::::::::: .::.:....:::.::.:: :  ... .: ...:.::.:  ..: :::..
NP_001 TGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMA
             610       620       630       640       650       660 

           1200      1210      1220      1230      1240      1250  
pF1KE1 ELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSL
       :. ::::::  ::  ::...:::::::.:.:: ..: :. . .:  :    .:.::.: :
NP_001 EMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHEL
             670       680       690       700       710       720 

           1260      1270      1280      1290      1300      1310  
pF1KE1 VEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEV
       .   .:  .:   :.. ..       ..::.:.::.  ::.: .:.:...:.:::.:..:
NP_001 TALANQIPTVNNLHVTALT-------TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV
             730       740              750       760       770    

           1320      1330      1340      1350      1360            
pF1KE1 IQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL            
       :. ...:: :.:.                                               
NP_001 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS
          780       790       800       810       820       830    

>>XP_011531169 (OMIM: 120435,158320,276300,609309) PREDI  (924 aa)
 initn: 678 init1: 428 opt: 590  Z-score: 470.1  bits: 98.8 E(85289): 1.9e-19
Smith-Waterman score: 835; 26.8% identity (56.9% similar) in 921 aa overlap (430-1325:40-853)

     400       410       420       430       440           450     
pF1KE1 EDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSEL----GLVFMKGN
                                     : ::  .  :::... :.    :.. . : 
XP_011 QLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGP
      10        20        30        40        50        60         

         460       470        480       490       500       510    
pF1KE1 WAHSGFPEIAFGRYS-DSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREIC
        . ...  ....... .:.: :   ..:  ..:.      . :   . :: .      . 
XP_011 AGAKNLQSVVLSKMNFESFV-KDLLLVRQYRVEV-----YKNRAGNKASKENDWY---LA
      70        80         90       100            110          120

          520         530       540       550       560       570  
pF1KE1 RIITKG--TQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
          . :  .:  ..: :. . . :  ....: .  :..   :  :: .::.   :. . .
XP_011 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ---RQVGVGYVDSIQRKLGLCE
              130       140       150          160       170       

            580       590       600       610       620       630  
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
       : :. . : ...:. .  : . ..  :. . .      ..:   .:.: :  ..   :. 
XP_011 FPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----GKLRQIIQRGGILITERKKADF
       180       190       200       210            220       230  

            640       650       660       670       680       690  
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
       . . . ..              : ..:::  .:. . .. :  ....:.:.:.. . .: 
XP_011 STKDIYQD--------------LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFL-
            240                     250       260       270        

            700        710       720       730       740       750 
pF1KE1 KCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTN
             ::::  .:: ..     :          :.   : : :: ...  :..: .:. 
XP_011 ------ELLSDDSNFGQFELTTFD----------FS---QYMKLDIAAVRALNLF-QGSV
             280       290                    300       310        

               760       770       780       790       800         
pF1KE1 GSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVV
        .: :.  :   .. :.:: :.::..::.  :: ..  :..::. .: . :   .. ...
XP_011 EDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAF-VEDAELRQTL
       320       330       340       350       360        370      

     810         820       830               840        850        
pF1KE1 E--LLKKLPDLERLLSKIHNVGSPLKS--------QNHPDS-RAIMYEETTYSKKKIIDF
       .  ::...:::.:: .:..  .. :..        .. :.  .:.  .:  ..:  .  :
XP_011 QEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVF
        380       390       400       410       420       430      

      860        870       880       890       900       910       
pF1KE1 LSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFD
       .. :  ..  . :.  ..: . :      . :: . .     .  :.:. ::   .   :
XP_011 VTPLTDLRSDFSKFQEMIETTLD------MDQVENHEFLVKPSFDPNLS-ELR--EIMND
        440       450             460       470        480         

       920       930       940       950       960       970       
pF1KE1 HEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRY
        ::  .. ::.  :. :   : .  .:. . .. . :      :. :.      . ::  
XP_011 LEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYYF----RVTCKE---EKVLRNN-
       490         500        510       520              530       

       980       990      1000      1010      1020      1030       
pF1KE1 QLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLF
            .::.: ..      :.  :  .   :.  :.   :  . :: .:. .:.     .
XP_011 -----KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKE-----I
             540            550       560       570       580      

      1040       1050      1060      1070      1080      1090      
pF1KE1 YNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRH
        :....: .  :.  . .: ::... .:. : :.  :. ::.::  :     . ::.:::
XP_011 VNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAIL--EKGQGRIILKASRH
             590       600       610       620         630         

       1100        1110      1120      1130      1140      1150    
pF1KE1 PCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMA
        :.      :.  :::::. .       :. : .  ..:::::::::: .::.:....::
XP_011 ACVE---VQDEIAFIPNDVYF-------EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMA
     640          650              660       670       680         

         1160      1170      1180      1190      1200      1210    
pF1KE1 QMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDE
       :.::.:: :  ... .: ...:.::.:  ..: :::..:. ::::::  ::  ::...::
XP_011 QIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDE
     690       700       710       720       730       740         

         1220      1230      1240      1250      1260      1270    
pF1KE1 LGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENE
       :::::.:.:: ..: :. . .:  :    .:.::.: :.   .:  .:   :.. ..   
XP_011 LGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALT---
     750       760       770       780       790       800         

         1280      1290      1300      1310      1320      1330    
pF1KE1 CEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFR
           ..::.:.::.  ::.: .:.:...:.:::.:..::. ...:: :.:.         
XP_011 ----TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQG
            810       820       830       840       850       860  

         1340      1350      1360                                  
pF1KE1 EVCLASERSTVDAEAVHKLLTLIKEL                                  
                                                                   
XP_011 YDIMEPAAKKCYLERENLRVTEPKDQCLILLTWKRKLRGGKRSACSRPERQNQGSATPSA
            870       880       890       900       910       920  

>>NP_000242 (OMIM: 120435,158320,276300,609309) DNA mism  (934 aa)
 initn: 678 init1: 428 opt: 590  Z-score: 470.0  bits: 98.8 E(85289): 1.9e-19
Smith-Waterman score: 835; 26.8% identity (56.9% similar) in 921 aa overlap (430-1325:40-853)

     400       410       420       430       440           450     
pF1KE1 EDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSEL----GLVFMKGN
                                     : ::  .  :::... :.    :.. . : 
NP_000 QLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGP
      10        20        30        40        50        60         

         460       470        480       490       500       510    
pF1KE1 WAHSGFPEIAFGRYS-DSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREIC
        . ...  ....... .:.: :   ..:  ..:.      . :   . :: .      . 
NP_000 AGAKNLQSVVLSKMNFESFV-KDLLLVRQYRVEV-----YKNRAGNKASKENDWY---LA
      70        80         90       100            110          120

          520         530       540       550       560       570  
pF1KE1 RIITKG--TQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
          . :  .:  ..: :. . . :  ....: .  :..   :  :: .::.   :. . .
NP_000 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ---RQVGVGYVDSIQRKLGLCE
              130       140       150          160       170       

            580       590       600       610       620       630  
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
       : :. . : ...:. .  : . ..  :. . .      ..:   .:.: :  ..   :. 
NP_000 FPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----GKLRQIIQRGGILITERKKADF
       180       190       200       210            220       230  

            640       650       660       670       680       690  
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
       . . . ..              : ..:::  .:. . .. :  ....:.:.:.. . .: 
NP_000 STKDIYQD--------------LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFL-
            240                     250       260       270        

            700        710       720       730       740       750 
pF1KE1 KCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTN
             ::::  .:: ..     :          :.   : : :: ...  :..: .:. 
NP_000 ------ELLSDDSNFGQFELTTFD----------FS---QYMKLDIAAVRALNLF-QGSV
             280       290                    300       310        

               760       770       780       790       800         
pF1KE1 GSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVV
        .: :.  :   .. :.:: :.::..::.  :: ..  :..::. .: . :   .. ...
NP_000 EDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAF-VEDAELRQTL
       320       330       340       350       360        370      

     810         820       830               840        850        
pF1KE1 E--LLKKLPDLERLLSKIHNVGSPLKS--------QNHPDS-RAIMYEETTYSKKKIIDF
       .  ::...:::.:: .:..  .. :..        .. :.  .:.  .:  ..:  .  :
NP_000 QEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVF
        380       390       400       410       420       430      

      860        870       880       890       900       910       
pF1KE1 LSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFD
       .. :  ..  . :.  ..: . :      . :: . .     .  :.:. ::   .   :
NP_000 VTPLTDLRSDFSKFQEMIETTLD------MDQVENHEFLVKPSFDPNLS-ELR--EIMND
        440       450             460       470        480         

       920       930       940       950       960       970       
pF1KE1 HEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRY
        ::  .. ::.  :. :   : .  .:. . .. . :      :. :.      . ::  
NP_000 LEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYYF----RVTCKE---EKVLRNN-
       490         500        510       520              530       

       980       990      1000      1010      1020      1030       
pF1KE1 QLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLF
            .::.: ..      :.  :  .   :.  :.   :  . :: .:. .:.     .
NP_000 -----KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKE-----I
             540            550       560       570       580      

      1040       1050      1060      1070      1080      1090      
pF1KE1 YNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRH
        :....: .  :.  . .: ::... .:. : :.  :. ::.::  :     . ::.:::
NP_000 VNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAIL--EKGQGRIILKASRH
             590       600       610       620         630         

       1100        1110      1120      1130      1140      1150    
pF1KE1 PCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMA
        :.      :.  :::::. .       :. : .  ..:::::::::: .::.:....::
NP_000 ACVE---VQDEIAFIPNDVYF-------EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMA
     640          650              660       670       680         

         1160      1170      1180      1190      1200      1210    
pF1KE1 QMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDE
       :.::.:: :  ... .: ...:.::.:  ..: :::..:. ::::::  ::  ::...::
NP_000 QIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDE
     690       700       710       720       730       740         

         1220      1230      1240      1250      1260      1270    
pF1KE1 LGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENE
       :::::.:.:: ..: :. . .:  :    .:.::.: :.   .:  .:   :.. ..   
NP_000 LGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALT---
     750       760       770       780       790       800         

         1280      1290      1300      1310      1320      1330    
pF1KE1 CEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFR
           ..::.:.::.  ::.: .:.:...:.:::.:..::. ...:: :.:.         
NP_000 ----TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQG
            810       820       830       840       850       860  

         1340      1350      1360                                  
pF1KE1 EVCLASERSTVDAEAVHKLLTLIKEL                                  
                                                                   
NP_000 YDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSF
            870       880       890       900       910       920  




1360 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 02:29:50 2016 done: Mon Nov  7 02:29:52 2016
 Total Scan time: 13.580 Total Display time:  0.470

Function used was FASTA [36.3.4 Apr, 2011]
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