Result of FASTA (omim) for pF1KE1004
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1004, 162 aa
  1>>>pF1KE1004 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6476+/-0.000317; mu= 15.6247+/- 0.020
 mean_var=60.8821+/-12.181, 0's: 0 Z-trim(115.7): 30  B-trim: 0 in 0/55
 Lambda= 0.164373
 statistics sampled from 26261 (26291) to 26261 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.308), width:  16
 Scan time:  5.170

The best scores are:                                      opt bits E(85289)
XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like s ( 162) 1068 261.2 5.4e-70
NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [H ( 162) 1068 261.2 5.4e-70
NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 ( 162) 1068 261.2 5.4e-70
XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like s ( 177) 1039 254.3 6.8e-68
NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [H ( 162)  728 180.5   1e-45
XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like s ( 195)  728 180.6 1.2e-45
NP_004576 (OMIM: 605092) retinoic acid receptor re ( 164)  543 136.7 1.6e-32
XP_016862412 (OMIM: 606487) PREDICTED: phospholipi ( 168)  487 123.4 1.7e-28
NP_065119 (OMIM: 606487) phospholipid-metabolizing ( 273)  487 123.6 2.4e-28
XP_011511337 (OMIM: 606487) PREDICTED: phospholipi ( 339)  465 118.4 1.1e-26
XP_011511336 (OMIM: 606487) PREDICTED: phospholipi ( 342)  465 118.4 1.1e-26
XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159)  455 115.8 3.1e-26
XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159)  455 115.8 3.1e-26
XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 268)  455 116.0 4.6e-26
NP_001140201 (OMIM: 611474) Ca(2+)-independent N-a ( 269)  455 116.0 4.6e-26
NP_473449 (OMIM: 611474) Ca(2+)-independent N-acyl ( 279)  455 116.0 4.7e-26
NP_001140200 (OMIM: 611474) Ca(2+)-independent N-a ( 253)  353 91.8 8.3e-19
XP_011543054 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 167)  288 76.2 2.7e-14


>>XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like suppr  (162 aa)
 initn: 1068 init1: 1068 opt: 1068  Z-score: 1377.6  bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
       ::::::::::::::::::::::::::::::::::::::::::
XP_006 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [Homo   (162 aa)
 initn: 1068 init1: 1068 opt: 1068  Z-score: 1377.6  bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
       ::::::::::::::::::::::::::::::::::::::::::
NP_009 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 [Ho  (162 aa)
 initn: 1068 init1: 1068 opt: 1068  Z-score: 1377.6  bits: 261.2 E(85289): 5.4e-70
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160  

>>XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like suppr  (177 aa)
 initn: 1039 init1: 1039 opt: 1039  Z-score: 1339.9  bits: 254.3 E(85289): 6.8e-68
Smith-Waterman score: 1039; 100.0% identity (100.0% similar) in 158 aa overlap (5-162:20-177)

                              10        20        30        40     
pF1KE1                MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
                          :::::::::::::::::::::::::::::::::::::::::
XP_011 MKTQRSSWCQLLLHRIGQRIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE1 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
               70        80        90       100       110       120

         110       120       130       140       150       160  
pF1KE1 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
              130       140       150       160       170       

>>NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [Homo   (162 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 941.9  bits: 180.5 E(85289): 1e-45
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)

               10        20        30        40        50        60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
            :.:. :::::: :  : :::::::::::::::: ::.::::::::.::::.::::
NP_060 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
       :::::  :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_060 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
               70        80        90       100       110       120

              130       140       150       160  
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
       ::::.:::::  .. ...::.  ::: ::.:....:.::..:
NP_060 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
              130       140       150       160  

>>XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like suppr  (195 aa)
 initn: 729 init1: 709 opt: 728  Z-score: 940.8  bits: 180.6 E(85289): 1.2e-45
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:39-195)

                                        10        20        30     
pF1KE1                          MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVH
                                     :.:. :::::: :  : :::::::::::::
XP_011 RVFQFWLQSICIPTLKLFVCLFVYSLKRARPRPRLGDLIEISRFGYAHWAIYVGDGYVVH
       10        20        30        40        50        60        

          40        50        60        70        80        90     
pF1KE1 LAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR
       ::: ::.::::::::.::::.:::::::::  :::.:.:.:::::::.:.::: .::..:
XP_011 LAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKR
       70        80        90       100       110       120        

         100       110       120       130       140       150     
pF1KE1 AEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFS
       ::::::::. :.:::.:::::::.:::::.:::::  .. ...::.  ::: ::.:....
XP_011 AEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLA
      130       140       150       160       170       180        

         160  
pF1KE1 RNKRQKQ
       :.::..:
XP_011 RSKRERQ
      190     

>>NP_004576 (OMIM: 605092) retinoic acid receptor respon  (164 aa)
 initn: 514 init1: 514 opt: 543  Z-score: 704.7  bits: 136.7 E(85289): 1.6e-32
Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-162:1-161)

               10        20        30        40        50        60
pF1KE1 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
       : .:  ::::::::::::  :.:::.:.:::::.:::::::  :::..::.:.:...: :
NP_004 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
       :.: : ::.:.  :.:::. : .:.: :   ::. :.:.:::.. :...:.::::::..:
NP_004 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
               70        80        90       100       110       120

              130       140       150       160     
pF1KE1 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ   
       ::: .:  ::. . . ..::  .:. . . :  :.  . ::.   
NP_004 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
              130       140        150       160    

>>XP_016862412 (OMIM: 606487) PREDICTED: phospholipid-me  (168 aa)
 initn: 454 init1: 285 opt: 487  Z-score: 632.8  bits: 123.4 E(85289): 1.7e-28
Smith-Waterman score: 487; 46.8% identity (79.2% similar) in 154 aa overlap (8-161:15-166)

                      10        20        30        40        50   
pF1KE1        MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSA
                     : ::::::.::: :.:::.:.:::::...:: . .  :. .:. :.
XP_016 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSV
               10        20        30        40        50          

            60        70        80        90       100       110   
pF1KE1 LTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENC
       ...::.:: .:: ::.:.: :..:::.:. : :::  .::.:.: ..:::: :.:  .::
XP_016 FSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC
      60        70        80        90       100       110         

           120       130       140       150       160   
pF1KE1 EHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 
       ::::. :::: . :.:.  .: ..  .  .....:..: .: ...: :  
XP_016 EHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAKYY
     120       130       140       150        160        

>>NP_065119 (OMIM: 606487) phospholipid-metabolizing enz  (273 aa)
 initn: 454 init1: 285 opt: 487  Z-score: 629.9  bits: 123.6 E(85289): 2.4e-28
Smith-Waterman score: 487; 46.8% identity (79.2% similar) in 154 aa overlap (8-161:120-271)

                                      10        20        30       
pF1KE1                        MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLA
                                     : ::::::.::: :.:::.:.:::::...:
NP_065 TQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIA
      90       100       110       120       130       140         

        40        50        60        70        80        90       
pF1KE1 PPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAE
       : . .  :. .:. :....::.:: .:: ::.:.: :..:::.:. : :::  .::.:.:
NP_065 PVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSE
     150        160       170       180       190       200        

       100       110       120       130       140       150       
pF1KE1 ELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRN
        ..:::: :.:  .::::::. :::: . :.:.  .: ..  .  .....:..: .: ..
NP_065 FVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKG
      210       220       230       240       250       260        

       160   
pF1KE1 KRQKQ 
       .: :  
NP_065 QRAKYY
       270   

>>XP_011511337 (OMIM: 606487) PREDICTED: phospholipid-me  (339 aa)
 initn: 454 init1: 285 opt: 465  Z-score: 600.4  bits: 118.4 E(85289): 1.1e-26
Smith-Waterman score: 465; 53.7% identity (82.1% similar) in 123 aa overlap (8-130:120-241)

                                      10        20        30       
pF1KE1                        MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLA
                                     : ::::::.::: :.:::.:.:::::...:
XP_011 TQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIA
      90       100       110       120       130       140         

        40        50        60        70        80        90       
pF1KE1 PPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAE
       : . .  :. .:. :....::.:: .:: ::.:.: :..:::.:. : :::  .::.:.:
XP_011 PVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSE
     150        160       170       180       190       200        

       100       110       120       130       140       150       
pF1KE1 ELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRN
        ..:::: :.:  .::::::. :::: . :.:.                           
XP_011 FVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQIIQLKDSKPINKWQNQNSKENGLPLGLC
      210       220       230       240       250       260        

       160                                                         
pF1KE1 KRQKQ                                                       
                                                                   
XP_011 TFDSLMVPTEKCALNHKYETGHFGGYVSVSIFIFSNRRLRLNHSSNNVNISNSPKANSTW
      270       280       290       300       310       320        




162 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:21:23 2016 done: Sat Nov  5 13:21:24 2016
 Total Scan time:  5.170 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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