Result of FASTA (omim) for pF1KB7646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7646, 390 aa
  1>>>pF1KB7646 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.4985+/-0.000412; mu= -2.6694+/- 0.026
 mean_var=381.1587+/-77.058, 0's: 0 Z-trim(122.8): 10  B-trim: 0 in 0/61
 Lambda= 0.065693
 statistics sampled from 41538 (41561) to 41538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.487), width:  16
 Scan time: 10.200

The best scores are:                                      opt bits E(85289)
NP_006283 (OMIM: 114480,601387) tumor susceptibili ( 390) 2604 260.2 6.1e-69
XP_005253165 (OMIM: 114480,601387) PREDICTED: tumo ( 338) 2284 229.8 7.5e-60
NP_001284700 (OMIM: 610985) ubiquitin-conjugating  ( 215)  566 66.8 5.7e-11
NP_060784 (OMIM: 610985) ubiquitin-conjugating enz ( 379)  566 67.0 8.4e-11
NP_001035787 (OMIM: 610985) ubiquitin-conjugating  ( 471)  566 67.1 9.7e-11
NP_001248314 (OMIM: 610985) ubiquitin-conjugating  ( 341)  481 58.9 2.1e-08
NP_001248312 (OMIM: 610985) ubiquitin-conjugating  ( 357)  393 50.6 6.9e-06
NP_001248311 (OMIM: 610985) ubiquitin-conjugating  ( 449)  393 50.7 8.1e-06


>>NP_006283 (OMIM: 114480,601387) tumor susceptibility g  (390 aa)
 initn: 2604 init1: 2604 opt: 2604  Z-score: 1358.7  bits: 260.2 E(85289): 6.1e-69
Smith-Waterman score: 2604; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 ALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFL
              310       320       330       340       350       360

              370       380       390
pF1KB7 KHVRLLSRKQFQLRALMQKARKTAGLSDLY
       ::::::::::::::::::::::::::::::
NP_006 KHVRLLSRKQFQLRALMQKARKTAGLSDLY
              370       380       390

>>XP_005253165 (OMIM: 114480,601387) PREDICTED: tumor su  (338 aa)
 initn: 2284 init1: 2284 opt: 2284  Z-score: 1195.5  bits: 229.8 E(85289): 7.5e-60
Smith-Waterman score: 2284; 100.0% identity (100.0% similar) in 338 aa overlap (53-390:1-338)

             30        40        50        60        70        80  
pF1KB7 RETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPY
                                     ::::::::::::::::::::::::::::::
XP_005                               MNLTGTIPVPYRGNTYNIPICLWLLDTYPY
                                             10        20        30

             90       100       110       120       130       140  
pF1KB7 NPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVF
               40        50        60        70        80        90

            150       160       170       180       190       200  
pF1KB7 SRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSS
              100       110       120       130       140       150

            210       220       230       240       250       260  
pF1KB7 QYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEED
              160       170       180       190       200       210

            270       280       290       300       310       320  
pF1KB7 LKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTA
              220       230       240       250       260       270

            330       340       350       360       370       380  
pF1KB7 PLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARK
              280       290       300       310       320       330

            390
pF1KB7 TAGLSDLY
       ::::::::
XP_005 TAGLSDLY
               

>>NP_001284700 (OMIM: 610985) ubiquitin-conjugating enzy  (215 aa)
 initn: 565 init1: 565 opt: 566  Z-score: 318.0  bits: 66.8 E(85289): 5.7e-11
Smith-Waterman score: 566; 49.7% identity (80.0% similar) in 165 aa overlap (8-172:8-167)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
              :.....:::.:::::.:  :: ...  .:  .:.:::.:.:...:.:.:::::
NP_001 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
       : :.:::::::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::
NP_001 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       .: ..:::. ::. : .: :..:  .:.:    :.      .:.  .  :.:        
NP_001 KSVIVGLIKEMIAKFQEELPMYS--LSSSDEARQVDL---LAYIAKITEGVSDTNSKSWA
              130       140         150          160       170     

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
                                                                   
NP_001 NHENKTVNKITVVGGGELGIACTLAISAKVESRSVTQAGV                    
         180       190       200       210                         

>>NP_060784 (OMIM: 610985) ubiquitin-conjugating enzyme   (379 aa)
 initn: 550 init1: 550 opt: 566  Z-score: 315.0  bits: 67.0 E(85289): 8.4e-11
Smith-Waterman score: 566; 49.7% identity (80.0% similar) in 165 aa overlap (8-172:8-167)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
              :.....:::.:::::.:  :: ...  .:  .:.:::.:.:...:.:.:::::
NP_060 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
       : :.:::::::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::
NP_060 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       .: ..:::. ::. : .: :..:  .:.:    :.      .:.  .  :.:        
NP_060 KSVIVGLIKEMIAKFQEELPMYS--LSSSDEARQVDL---LAYIAKITEGVSDTNSKSWA
              130       140         150          160       170     

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
                                                                   
NP_060 NHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVE
         180       190       200       210       220       230     

>>NP_001035787 (OMIM: 610985) ubiquitin-conjugating enzy  (471 aa)
 initn: 550 init1: 550 opt: 566  Z-score: 313.8  bits: 67.1 E(85289): 9.7e-11
Smith-Waterman score: 566; 49.7% identity (80.0% similar) in 165 aa overlap (8-172:8-167)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
              :.....:::.:::::.:  :: ...  .:  .:.:::.:.:...:.:.:::::
NP_001 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
       : :.:::::::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::
NP_001 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       .: ..:::. ::. : .: :..:  .:.:    :.      .:.  .  :.:        
NP_001 KSVIVGLIKEMIAKFQEELPMYS--LSSSDEARQVDL---LAYIAKITEGVSDTNSKSWA
              130       140         150          160       170     

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
                                                                   
NP_001 NHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVE
         180       190       200       210       220       230     

>>NP_001248314 (OMIM: 610985) ubiquitin-conjugating enzy  (341 aa)
 initn: 467 init1: 467 opt: 481  Z-score: 272.0  bits: 58.9 E(85289): 2.1e-08
Smith-Waterman score: 481; 51.5% identity (80.6% similar) in 134 aa overlap (39-172:1-129)

       10        20        30        40        50        60        
pF1KB7 KKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTY
                                     .:.:::.:.:...:.:.:::::: :.::::
NP_001                               MDTYVFKDSSQKDLLNFTGTIPVMYQGNTY
                                             10        20        30

       70        80        90       100       110       120        
pF1KB7 NIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLI
       :::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::.: ..:::
NP_001 NIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLI
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KB7 QVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGC
       . ::. : .: :..:  .:.:    :.      .:.  .  :.:                
NP_001 KEMIAKFQEELPMYS--LSSSDEARQVD---LLAYIAKITEGVSDTNSKSWANHENKTVN
              100         110          120       130       140     

      190       200       210       220       230       240        
pF1KB7 PYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDR
                                                                   
NP_001 KITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSAS
         150       160       170       180       190       200     

>>NP_001248312 (OMIM: 610985) ubiquitin-conjugating enzy  (357 aa)
 initn: 429 init1: 368 opt: 393  Z-score: 226.7  bits: 50.6 E(85289): 6.9e-06
Smith-Waterman score: 421; 41.8% identity (67.3% similar) in 165 aa overlap (8-172:8-145)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
              :.....:::.:::::.:  :: ...  .:  .:.:                  
NP_001 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTY------------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
           :::::::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::
NP_001 ----GNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
                 50        60        70        80        90        

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       .: ..:::. ::. : .: :..:  .:.:    :.      .:.  .  :.:        
NP_001 KSVIVGLIKEMIAKFQEELPMYS--LSSSDEARQVDL---LAYIAKITEGVSDTNSKSWA
      100       110       120         130          140       150   

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
                                                                   
NP_001 NHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVE
           160       170       180       190       200       210   

>>NP_001248311 (OMIM: 610985) ubiquitin-conjugating enzy  (449 aa)
 initn: 429 init1: 368 opt: 393  Z-score: 225.4  bits: 50.7 E(85289): 8.1e-06
Smith-Waterman score: 421; 41.8% identity (67.3% similar) in 165 aa overlap (8-172:8-145)

               10        20        30        40        50        60
pF1KB7 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIP
              :.....:::.:::::.:  :: ...  .:  .:.:                  
NP_001 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTY------------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB7 VPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHP
           :::::::: .:.::..:. :::::.:::..: : .::::::.:.::::::..:.::
NP_001 ----GNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
                 50        60        70        80        90        

              130       140       150       160       170       180
pF1KB7 QSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPP
       .: ..:::. ::. : .: :..:  .:.:    :.      .:.  .  :.:        
NP_001 KSVIVGLIKEMIAKFQEELPMYS--LSSSDEARQVDL---LAYIAKITEGVSDTNSKSWA
      100       110       120         130          140       150   

              190       200       210       220       230       240
pF1KB7 NPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRW
                                                                   
NP_001 NHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVE
           160       170       180       190       200       210   




390 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:13:53 2016 done: Fri Nov  4 20:13:55 2016
 Total Scan time: 10.200 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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