Result of FASTA (omim) for pF1KB9552
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9552, 466 aa
  1>>>pF1KB9552 466 - 466 aa - 466 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.5501+/-0.000312; mu= -0.6491+/- 0.020
 mean_var=232.4800+/-47.078, 0's: 0 Z-trim(123.7): 144  B-trim: 43 in 1/60
 Lambda= 0.084117
 statistics sampled from 43717 (43898) to 43717 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.515), width:  16
 Scan time: 10.400

The best scores are:                                      opt bits E(85289)
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 3261 408.2 2.4e-113
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 1350 176.3 1.7e-43
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446)  869 117.9 5.6e-26
NP_071899 (OMIM: 610928,613674) transcription fact ( 414)  436 65.4 3.5e-10
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315)  422 63.6 9.1e-10
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384)  414 62.7 2.1e-09
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317)  412 62.4 2.1e-09
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276)  410 62.1 2.2e-09
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233)  408 61.8 2.3e-09
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446)  407 61.9 4.2e-09
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388)  405 61.6 4.5e-09
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474)  405 61.6 5.3e-09
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391)  400 61.0 6.9e-09
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240)  391 59.7 9.9e-09
NP_003099 (OMIM: 600898,615866) transcription fact ( 441)  381 58.7 3.7e-08
NP_821078 (OMIM: 604975,616803) transcription fact ( 377)  343 54.0 8.1e-07
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415)  343 54.1 8.7e-07
NP_001248343 (OMIM: 604975,616803) transcription f ( 642)  343 54.2 1.2e-06
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715)  343 54.2 1.4e-06
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715)  343 54.2 1.4e-06
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715)  343 54.2 1.4e-06
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715)  343 54.2 1.4e-06
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716)  343 54.2 1.4e-06
NP_001317714 (OMIM: 604975,616803) transcription f ( 728)  343 54.2 1.4e-06
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729)  343 54.2 1.4e-06
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750)  343 54.2 1.4e-06
NP_694534 (OMIM: 604975,616803) transcription fact ( 750)  343 54.2 1.4e-06
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751)  343 54.2 1.4e-06
NP_001248344 (OMIM: 604975,616803) transcription f ( 753)  343 54.2 1.4e-06
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754)  343 54.2 1.4e-06
NP_008871 (OMIM: 604975,616803) transcription fact ( 763)  343 54.2 1.4e-06
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764)  343 54.2 1.4e-06
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792)  343 54.3 1.5e-06
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793)  343 54.3 1.5e-06
NP_001139283 (OMIM: 607257) transcription factor S ( 801)  338 53.6 2.3e-06
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804)  338 53.6 2.3e-06
NP_001139291 (OMIM: 607257) transcription factor S ( 841)  338 53.7 2.3e-06
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808)  323 51.8   8e-06
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204)  309 49.7 8.6e-06
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621)  314 50.7 1.4e-05
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622)  314 50.7 1.4e-05
XP_011532722 (OMIM: 606698) PREDICTED: transcripti ( 448)  293 48.0 6.2e-05


>>NP_008872 (OMIM: 602229,609136,611584,613266) transcri  (466 aa)
 initn: 3261 init1: 3261 opt: 3261  Z-score: 2155.9  bits: 408.2 E(85289): 2.4e-113
Smith-Waterman score: 3261; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)

               10        20        30        40        50        60
pF1KB9 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 KLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 GKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 PPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTET
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 AGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHSGQASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHSGQASG
              370       380       390       400       410       420

              430       440       450       460      
pF1KB9 LYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
              430       440       450       460      

>>NP_000337 (OMIM: 114290,608160,616425) transcription f  (509 aa)
 initn: 1439 init1: 805 opt: 1350  Z-score: 902.0  bits: 176.3 E(85289): 1.7e-43
Smith-Waterman score: 1624; 54.0% identity (72.2% similar) in 493 aa overlap (18-456:13-499)

               10        20        30            40        50      
pF1KB9 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGG----GSGLRASPGPGELGKVKK
                        :. . :: . .:... :..:.    :::  .     . .   :
NP_000      MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPK
                    10        20        30        40        50     

         60          70        80        90       100       110    
pF1KB9 EQQD--GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVW
        . :   :...:::::::::::::::.:::::::::::::::.::.::::::::::::::
NP_000 GEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVW
          60        70        80        90       100       110     

          120       130       140       150       160       170    
pF1KB9 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQ
       ::::::::::::::::::::::::::::::::::.::::.:::::::.::::::::::::
NP_000 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQ
         120       130       140       150       160       170     

          180       190       200       210       220        230   
pF1KB9 PRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSD-GNPEHPSG
       :::::. : .:.:::    :: .    . .: .:. . :  : . :  ::.  .: . ::
NP_000 PRRRKSVKNGQAEAE----EATEQTHISPNAIFKALQADSPHSSSG--MSEVHSPGEHSG
         180       190           200       210         220         

           240       250       260        270       280       290  
pF1KB9 QSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGK-PHIDFGNVDIGEISHEVMSNMETF
       ::.:::::::::::..: :::: ::.:: . :::. : ::: .:::::.: .:.::.:::
NP_000 QSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETF
     230       240       250       260       270       280         

            300           310       320        330           340   
pF1KB9 DVAELDQYLPPNGHPG----HVSSYSAAGYGLGSALAV-ASGHSAWISK----PPGVALP
       :: :.:::::::::::    : .   ...::..:. :. ::.  .:.::    ::    :
NP_000 DVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQP
     290       300       310       320       330       340         

           350            360                                  370 
pF1KB9 TVSPPGVDAKAQVKTE-----TAGPQ---------------------------GPPHYTD
         .::. .:  : ..      .: ::                           .: ::..
NP_000 PQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSE
     350       360       370       380       390       400         

               380       390       400       410        420        
pF1KB9 QP--STSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHS-GQASGLYSAFSYM
       :   : .::::. ..::::. ..: :.: :.::.::: :. ::.:. ::..::::.:.::
NP_000 QQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYM
     410       420       430       440       450       460         

      430       440         450       460      
pF1KB9 GPSQRPLYTAISDPS--PSGPQSHSPTHWEQPVYTTLSRP
       .:.:::.:: :.: :  :: ::.::: :::          
NP_000 NPAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
     470       480       490       500         

>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H  (446 aa)
 initn: 1010 init1: 579 opt: 869  Z-score: 587.3  bits: 117.9 E(85289): 5.6e-26
Smith-Waterman score: 1281; 50.2% identity (68.1% similar) in 474 aa overlap (10-466:2-446)

               10        20        30          40         50       
pF1KB9 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLG--PDGGGGGSGLRA-SPGPGELG-KVKK
                ...: . :. : :   :.: :..   :. . .    : : : :. :  :  
NP_055         MLDMSEARSQPP-CSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGG
                       10         20        30        40        50 

         60         70        80        90         100       110   
pF1KB9 EQQD-GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNG--ASKSKPHVKRPMNAFMV
        . : .:: :..::.:::.::::::.::::.::::::: .:  : :.:::::::::::::
NP_055 ARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMV
              60        70        80        90       100       110 

           120       130       140       150       160       170   
pF1KB9 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKY
       ::::::::::::::::::::::::::::::::.::.::::.:::::::.:::::::::::
NP_055 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY
             120       130       140       150       160       170 

           180       190       200       210       220       230   
pF1KB9 QPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSG
       ::::::..::  :...  .: :: :   .  : ::.      . : :.    :.  : .:
NP_055 QPRRRKSAKA--GHSDSDSG-AELGPHPGGGAVYKA------EAGLGDGHHHGD--H-TG
             180          190       200             210            

           240       250         260       270       280       290 
pF1KB9 QSHGPPTPPTTPKTELQSGKADP--KRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMET
       :.:::::::::::::::.. : :  : .::   ..:. .:::.::::.:.: :::..:..
NP_055 QTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDA
     220       230       240       250       260       270         

             300       310       320       330         340         
pF1KB9 FDVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISK--PPGVALPTVSPPG
       ::: :.::::: .: :.        : . :.:   :..  .:  :  : . : :: . : 
NP_055 FDVHEFDQYLPLGG-PAP----PEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGP-
     280       290            300       310       320       330    

     350       360       370       380       390       400         
pF1KB9 VDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQF-----DYSD
          . ..:::   :. : :: :::  :   : : :    .:: :.     :     ::.:
NP_055 --PRPHIKTEQ--PS-PGHYGDQPRGSP-DYGSCS--GQSSATPAAPAGPFAGSQGDYGD
             340          350        360         370       380     

          410       420       430       440       450        460   
pF1KB9 HQPSGPYYGHSGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPT-HWEQPVYTTL
        : :. : .. : : :::.   . .: .::  . . . . . : .:::: ::.:::::::
NP_055 LQASSYYGAYPGYAPGLYQYPCFHSP-RRPYASPLLN-GLALPPAHSPTSHWDQPVYTTL
         390       400       410        420        430       440   

          
pF1KB9 SRP
       .::
NP_055 TRP
          

>>NP_071899 (OMIM: 610928,613674) transcription factor S  (414 aa)
 initn: 451 init1: 410 opt: 436  Z-score: 303.8  bits: 65.4 E(85289): 3.5e-10
Smith-Waterman score: 466; 35.4% identity (55.4% similar) in 325 aa overlap (91-410:55-330)

               70        80        90       100       110       120
pF1KB9 GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARR
                                     :. . : .:.. ...::::::::::.  :.
NP_071 AGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERK
           30        40        50        60        70        80    

              130       140       150       160       170       180
pF1KB9 KLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKN
       .::.: : :::::::: ::: :. :. ..::::.:::::::.:: .:::.:::.:::::.
NP_071 RLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ
           90       100       110       120       130       140    

              190       200       210       220        230         
pF1KB9 GKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDG-NPEHP-SGQSHGP
        :  .   .  ::  .  : :  ::    : :    :  :    :: . . : .:   ::
NP_071 VKRLK---RVEGGFLH--GLAEPQA----AALG---PEGGRVAMDGLGLQFPEQGFPAGP
             150         160              170       180       190  

      240       250       260       270       280       290        
pF1KB9 PTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELD
       :  :  :.   ..:.    :: .:.:    : .:      :         . : :.. ::
NP_071 PLLP--PH---MGGHY---RDCQSLGA---PPLD------GY-------PLPTPDTSPLD
                 200          210                       220        

      300       310       320       330       340       350        
pF1KB9 QYLPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKT
          :    :    .. :: .  :.  :...   : .:   :   :   ::.   . ..  
NP_071 GVDPD---P----AFFAAPMP-GDCPAAGTYSYAQVSDYAG---PP-EPPAGPMHPRLGP
      230              240        250       260           270      

      360       370       380       390       400          410     
pF1KB9 ETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYS---DHQPSGPYYGHS
       : :::.  :     ::. .. : ... :  :..     .:: ...   .:.: ::     
NP_071 EPAGPS-IPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSP
        280        290       300       310       320       330     

         420       430       440       450       460               
pF1KB9 GQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP         
                                                                   
NP_071 PPEALPCRDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAI
         340       350       360       370       380       390     

>>NP_008874 (OMIM: 601947) transcription factor SOX-12 [  (315 aa)
 initn: 463 init1: 414 opt: 422  Z-score: 296.3  bits: 63.6 E(85289): 9.1e-10
Smith-Waterman score: 446; 33.2% identity (57.2% similar) in 271 aa overlap (103-369:39-285)

             80        90       100       110       120       130  
pF1KB9 REAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNA
                                     :.::::::::::.:  :::. ::.: .:::
NP_008 AKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNA
       10        20        30        40        50        60        

            140       150       160       170       180       190  
pF1KB9 ELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPG
       :.:: ::. :.::..:.: ::..::::::..:  :.:::::.::....:  :... . ::
NP_008 EISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPG
       70        80        90       100       110       120        

            200       210       220       230       240       250  
pF1KB9 GEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSG
       :   .:: . ..    . .:    ::.:.  . :.:   .: . .:         ::   
NP_008 G---SGGGSRLKP---GPQL----PGRGGRRAAGGPL--GGGAAAPEDDDEDDDEELLEV
         130          140           150         160       170      

            260       270       280       290       300       310  
pF1KB9 KADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNGHPGHVSS
       .   .  :: . .     .  : .  :.  .    . :   .:   .  : . .  .   
NP_008 RL-VETPGRELWR----MVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEE
         180           190       200       210       220       230 

            320       330          340       350        360        
pF1KB9 YSAAGYGLGSALAVASGHSA--WISK-PPGVALPTVSPPGVDAKAQVKT-ETAGPQGPPH
         ::.   :   .::::. .  ..:. :::       : :.: .:  .  .   :.:  :
NP_008 EEAAAAEEGEEETVASGEESLGFLSRLPPG-------PAGLDCSALDRDPDLQPPSGTSH
             240       250       260              270       280    

      370       380       390       400       410       420        
pF1KB9 YTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHSGQASGLYSAFSYM
       .                                                           
NP_008 FEFPDYCTPEVTEMIAGDWRPSSIADLVFTY                             
          290       300       310                                  

>>NP_060889 (OMIM: 137940,601618,607823) transcription f  (384 aa)
 initn: 446 init1: 386 opt: 414  Z-score: 289.9  bits: 62.7 E(85289): 2.1e-09
Smith-Waterman score: 414; 45.5% identity (63.6% similar) in 154 aa overlap (104-254:85-228)

            80        90       100       110       120       130   
pF1KB9 EAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAE
                                     ..::::::::::.  :..::.: : :::: 
NP_060 QRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAV
           60        70        80        90       100       110    

           140       150       160       170       180          190
pF1KB9 LSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAE---C
       ::: ::: :. :: ..::::.:::::::.:: .:::.:::.:::.:... :.        
NP_060 LSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLL
          120       130       140       150       160       170    

              200       210       220       230       240       250
pF1KB9 PGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQ
       ::    :     . :   ::.  .. :  :. . ::          : :::  .:   :.
NP_060 PGLAPPQPPPEPFPAASGSARAFRELPPLGAEF-DG---------LGLPTPERSPLDGLE
          180       190       200                 210       220    

              260       270       280       290       300       310
pF1KB9 SGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNGHPGHV
        :.:                                                        
NP_060 PGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYY
          230       240       250       260       270       280    

>>NP_003097 (OMIM: 184429,189960,206900) transcription f  (317 aa)
 initn: 544 init1: 396 opt: 412  Z-score: 289.7  bits: 62.4 E(85289): 2.1e-09
Smith-Waterman score: 457; 32.0% identity (58.4% similar) in 303 aa overlap (96-391:32-307)

          70        80        90       100        110       120    
pF1KB9 DKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKP-HVKRPMNAFMVWAQAARRKLAD
                                     : .:..: .:::::::::::... :::.:.
NP_003 YNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQ
              10        20        30        40        50        60 

          130       140       150       160       170       180    
pF1KB9 QYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAA
       . :..::.:.:: ::  :.::.:..:::::.::.:::  : :.::::::.:::. .    
NP_003 ENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMK
              70        80        90       100       110       120 

          190       200       210       220       230       240    
pF1KB9 QGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTT
       . .   :::    ::..  ..   .: :     : :  .   .  : .: :.:       
NP_003 KDKYTLPGGLLAPGGNSMASGVGVGAGL-----GAGVNQRMDSYAHMNGWSNGS------
             130       140            150       160       170      

          250       260       270       280       290       300    
pF1KB9 PKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPN
         . .:.  . :.. : . ..:.     .   :.. .... :.. .:.           :
NP_003 -YSMMQDQLGYPQHPGLN-AHGAAQMQPMHRYDVSALQYNSMTSSQTY----------MN
               180        190       200       210                  

          310          320       330       340          350        
pF1KB9 GHPGHVSSYS---AAGYGLGSALAVASGHSAWISKPPGVALPTVS-PP--GVDAKAQVKT
       : : .  :::   . :..:::  .:......  :.:: :.  . :  :  . : . ... 
NP_003 GSPTYSMSYSQQGTPGMALGSMGSVVKSEAS--SSPPVVTSSSHSRAPCQAGDLRDMISM
      220       230       240         250       260       270      

      360       370       380       390       400       410        
pF1KB9 ETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHSGQA
          : . :      ::  ...    : :  :.:                           
NP_003 YLPGAEVPE--PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM                 
        280         290       300       310                        

      420       430       440       450       460      
pF1KB9 SGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP

>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [  (276 aa)
 initn: 416 init1: 393 opt: 410  Z-score: 289.3  bits: 62.1 E(85289): 2.2e-09
Smith-Waterman score: 442; 34.2% identity (58.4% similar) in 281 aa overlap (100-368:2-268)

      70        80        90       100         110       120       
pF1KB9 VCIREAVSQVLSGYDWTLVPMPVRVNGASKSKP--HVKRPMNAFMVWAQAARRKLADQYP
                                     :::  ::::::::::::..: :::.:.. :
NP_009                              MSKPVDHVKRPMNAFMVWSRAQRRKMAQENP
                                            10        20        30 

       130       140       150       160       170       180       
pF1KB9 HLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGE
       ..::.:.:: ::  :.::.::.:::::.::.::: .: :.::::::.:::. .    . .
NP_009 KMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDK
              40        50        60        70        80        90 

       190       200       210       220         230       240     
pF1KB9 AECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEG-SPMSD-GNPEHPSGQSHGPPTPPTTP
          :   .  : . : .   :..   :   : :  : :  .:::. .. . .  .    :
NP_009 FAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFP
             100       110       120       130       140       150 

         250       260       270       280       290       300     
pF1KB9 KTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNG
       ..   .. :       . . .:.:   .. .:.:    :. :.   .  :    : :  :
NP_009 QSAAAAAAAA------AAAAAGSP---YSLLDLGSKMAEISSSSSGLPYASSLGY-PTAG
             160                170       180       190        200 

         310       320       330         340           350         
pF1KB9 HPGHVSSYSAAGYGLGSALAVASGHSAWISKP--PGVALP---TVSP-PGVDAK-AQVKT
           .... .:. . ..: :.:.::.    .:  ::  .:   .. : ::..   : .  
NP_009 ----AGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILL
                 210       220       230       240       250       

      360        370       380       390       400       410       
pF1KB9 ETAG-PQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHSGQ
          : ::  :.                                                 
NP_009 PGMGKPQLDPYPAAYAAAL                                         
       260       270                                               

>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens]  (233 aa)
 initn: 431 init1: 377 opt: 408  Z-score: 289.1  bits: 61.8 E(85289): 2.3e-09
Smith-Waterman score: 408; 41.8% identity (71.2% similar) in 153 aa overlap (104-248:49-196)

            80        90       100       110       120       130   
pF1KB9 EAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAE
                                     :::::::::::..: ::..:.: :..::.:
NP_008 ATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSE
       20        30        40        50        60        70        

           140       150       160       170       180       190   
pF1KB9 LSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGG
       .:: ::  :.::.:..::::.:::.::: .: .:.:::::.:::. ....: : ..:  :
NP_008 ISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKSSGA-GPSRCGQG
       80        90       100       110       120        130       

             200          210       220       230          240     
pF1KB9 EAE--QGGT---AAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGP---PTPPTTP
       ...  .::     .  .   :  . .: :. .. .  :.     :.::     :.: . :
NP_008 RGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGS----YGSSHCKLEAPSPCSLP
       140       150       160       170           180       190   

         250       260       270       280       290       300     
pF1KB9 KTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNG
       ...                                                         
NP_008 QSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL                    
           200       210       220       230                       

>>NP_005625 (OMIM: 300123,312000,313430) transcription f  (446 aa)
 initn: 434 init1: 377 opt: 407  Z-score: 284.3  bits: 61.9 E(85289): 4.2e-09
Smith-Waterman score: 430; 30.2% identity (55.9% similar) in 338 aa overlap (96-420:131-439)

          70        80        90       100       110       120     
pF1KB9 DKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQ
                                     :.. .. .:::::::::::... :::.: .
NP_005 AAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALE
              110       120       130       140       150       160

         130       140       150       160       170       180     
pF1KB9 YPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQ
        :..::.:.:: ::  :.::....:::::.::.:::  : :..:::::.:::. .    .
NP_005 NPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKK
              170       180       190       200       210       220

         190       200       210       220       230       240     
pF1KB9 GEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTP
        .   :.:    :..::  :   .:       : :. ..  .  : .: ..:  .     
NP_005 DKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLD--TYTHVNGWANGAYS-----
              230       240       250         260       270        

         250       260       270       280       290       300     
pF1KB9 KTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLP--P
        .. : : :.:     ::.    :               ..  :. .:.: : :: :  :
NP_005 LVQEQLGYAQPP----SMSSPPPP--------------PALPPMHRYDMAGL-QYSPMMP
           280           290                     300        310    

           310           320       330       340       350         
pF1KB9 NGHPGHVSSYSAA----GYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQ---V
        :  ....  .::    :::  .  :.:.. .:. ..:  .:  ...  ...   .   :
NP_005 PGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVV
          320       330       340       350       360       370    

        360       370           380       390       400       410  
pF1KB9 KTETAGPQGPPHYTDQPSTSQIA----YTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYY
       :.: ..:  ::  ... . . ..    . :. ::  :.:  . : :      :     : 
NP_005 KSEPSSP--PPAIASHSQRACLGDLRDMISMYLPPGGDAADAAS-PLPGGRLHGVHQHYQ
          380         390       400       410        420       430 

            420       430       440       450       460      
pF1KB9 GHSGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
       : .  ..:                                              
NP_005 GAGTAVNGTVPLTHI                                       
             440                                             




466 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:06:28 2016 done: Sat Nov  5 02:06:29 2016
 Total Scan time: 10.400 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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