Result of FASTA (omim) for pF1KB6564
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6564, 400 aa
  1>>>pF1KB6564 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.1633+/-0.000466; mu= 0.8321+/- 0.028
 mean_var=559.8048+/-124.610, 0's: 0 Z-trim(120.7): 1419  B-trim: 33 in 1/54
 Lambda= 0.054207
 statistics sampled from 33957 (36228) to 33957 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.425), width:  16
 Scan time:  8.710

The best scores are:                                      opt bits E(85289)
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 2665 223.4 7.6e-58
XP_016882478 (OMIM: 601263,615280) PREDICTED: dual ( 512) 2315 196.2 1.5e-49
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 2130 181.6   3e-45
XP_011520085 (OMIM: 163950,176872,615279) PREDICTE ( 371) 2099 179.1 1.5e-44
XP_016882480 (OMIM: 601263,615280) PREDICTED: dual ( 252) 1530 134.3 3.2e-31
XP_006722862 (OMIM: 601263,615280) PREDICTED: dual ( 307) 1528 134.3 3.9e-31
XP_016882479 (OMIM: 601263,615280) PREDICTED: dual ( 419) 1528 134.5 4.6e-31
XP_016877902 (OMIM: 163950,176872,615279) PREDICTE ( 217) 1135 103.3 5.9e-22
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412)  781 76.1 1.7e-13
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448)  781 76.2 1.8e-13
NP_002748 (OMIM: 602520) dual specificity mitogen- ( 438)  760 74.5 5.6e-13
XP_016877900 (OMIM: 163950,176872,615279) PREDICTE ( 367)  753 73.8 7.5e-13
XP_016877901 (OMIM: 163950,176872,615279) PREDICTE ( 345)  722 71.4 3.9e-12
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334)  640 64.9 3.3e-10
XP_011523328 (OMIM: 601254) PREDICTED: dual specif ( 337)  640 64.9 3.3e-10
XP_011523327 (OMIM: 601254) PREDICTED: dual specif ( 345)  640 64.9 3.3e-10
XP_016880347 (OMIM: 602315) PREDICTED: dual specif ( 318)  620 63.3 9.4e-10
XP_005256780 (OMIM: 602315) PREDICTED: dual specif ( 318)  620 63.3 9.4e-10
XP_011522261 (OMIM: 602315) PREDICTED: dual specif ( 318)  620 63.3 9.4e-10
XP_016880348 (OMIM: 602315) PREDICTED: dual specif ( 318)  620 63.3 9.4e-10
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318)  620 63.3 9.4e-10
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318)  620 63.3 9.4e-10
XP_016880346 (OMIM: 602315) PREDICTED: dual specif ( 343)  620 63.4 9.8e-10
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347)  620 63.4 9.9e-10
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399)  612 62.9 1.6e-09
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410)  612 62.9 1.7e-09
XP_011523329 (OMIM: 601254) PREDICTED: dual specif ( 278)  606 62.1 1.9e-09
XP_005257573 (OMIM: 601254) PREDICTED: dual specif ( 278)  606 62.1 1.9e-09
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278)  606 62.1 1.9e-09
XP_006722038 (OMIM: 601254) PREDICTED: dual specif ( 278)  606 62.1 1.9e-09
XP_011522260 (OMIM: 602315) PREDICTED: dual specif ( 298)  597 61.5 3.2e-09
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419)  579 60.3   1e-08
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435)  579 60.3   1e-08
XP_005256810 (OMIM: 601335) PREDICTED: dual specif ( 281)  567 59.1 1.6e-08
XP_011522278 (OMIM: 601335) PREDICTED: dual specif ( 319)  565 59.0 1.9e-08
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426)  543 57.5 7.1e-08
XP_006722863 (OMIM: 603014) PREDICTED: dual specif ( 442)  543 57.5 7.2e-08
XP_011522279 (OMIM: 601335) PREDICTED: dual specif ( 253)  513 54.8 2.8e-07
XP_005256812 (OMIM: 601335) PREDICTED: dual specif ( 253)  513 54.8 2.8e-07
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388)  508 54.7 4.5e-07
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456)  508 54.8 4.9e-07
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462)  508 54.8 4.9e-07
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519)  509 55.0 4.9e-07
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524)  509 55.0   5e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487)  508 54.9 5.1e-07
NP_006272 (OMIM: 605030) serine/threonine-protein  ( 491)  508 54.9 5.1e-07
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576)  509 55.1 5.2e-07
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580)  509 55.1 5.2e-07
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522)  508 54.9 5.2e-07
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404)  501 54.2 6.7e-07


>>NP_109587 (OMIM: 601263,615280) dual specificity mitog  (400 aa)
 initn: 2665 init1: 2665 opt: 2665  Z-score: 1159.5  bits: 223.4 E(85289): 7.6e-58
Smith-Waterman score: 2665; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
       ::::::::::::::::::::::::::::::::::::::::
NP_109 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
              370       380       390       400

>>XP_016882478 (OMIM: 601263,615280) PREDICTED: dual spe  (512 aa)
 initn: 2315 init1: 2315 opt: 2315  Z-score: 1010.6  bits: 196.2 E(85289): 1.5e-49
Smith-Waterman score: 2315; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_016 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKWFWEGRQPHSIL
              310       320       330       340       350       360

              370       380       390       400                    
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV                    
                                                                   
XP_016 LPPSTQQHLWRGLHRHVPQTTGKELRTPRCPQGRSMCVSSGRRGTAPHSWCRSCPGPLAC
              370       380       390       400       410       420

>>NP_002746 (OMIM: 163950,176872,615279) dual specificit  (393 aa)
 initn: 2120 init1: 1539 opt: 2130  Z-score: 933.4  bits: 181.6 E(85289): 3e-45
Smith-Waterman score: 2130; 80.4% identity (92.0% similar) in 398 aa overlap (2-399:1-391)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
        . ..::. : . .::.  .: . .. ...:.::  ::::::::::::::.:::::::::
NP_002  MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
                  10         20        30        40        50      

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       : :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
NP_002 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
NP_002 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       :.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_002 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
       :::::::::::::::::::.:::::::::::::::: .::  :    ::.     :::: 
NP_002 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRT
        240       250       260       270           280       290  

              310       320       330       340       350       360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
       ::::.:..:::::: :::::::::::::::::::.:::. .::.::::::::::::::::
NP_002 PGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADL
            300       310       320       330       340       350  

              370       380       390       400 
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV 
       :.:  :.:::::..::::::::::.:. ::::.:::..:  
NP_002 KQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
            360       370       380       390   

>>XP_011520085 (OMIM: 163950,176872,615279) PREDICTED: d  (371 aa)
 initn: 2106 init1: 1525 opt: 2099  Z-score: 920.6  bits: 179.1 E(85289): 1.5e-44
Smith-Waterman score: 2099; 85.3% identity (93.7% similar) in 367 aa overlap (33-399:7-369)

             10        20        30        40        50        60  
pF1KB6 ARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKA
                                     ::  ::::::::::::::.:::::::::: 
XP_011                         MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQ
                                       10        20        30      

             70        80        90       100       110       120  
pF1KB6 KVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVL
       :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::::
XP_011 KVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVL
         40        50        60        70        80        90      

            130       140       150       160       170       180  
pF1KB6 HECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLA
       ::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..::.
XP_011 HECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLT
        100       110       120       130       140       150      

            190       200       210       220       230       240  
pF1KB6 YLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGT
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 YLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGT
        160       170       180       190       200       210      

            250       260       270       280       290       300  
pF1KB6 HYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPG
       :::::::::::::::::.:::::::::::::::: .::  :    ::.     :::: ::
XP_011 HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRTPG
        220       230       240       250           260       270  

            310       320       330       340       350       360  
pF1KB6 RPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKM
       ::.:..:::::: :::::::::::::::::::.:::. .::.:::::::::::::::::.
XP_011 RPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQ
            280       290       300       310       320       330  

            370       380       390       400 
pF1KB6 LTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV 
       :  :.:::::..::::::::::.:. ::::.:::..:  
XP_011 LMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
            340       350       360       370 

>>XP_016882480 (OMIM: 601263,615280) PREDICTED: dual spe  (252 aa)
 initn: 1518 init1: 1518 opt: 1530  Z-score: 681.6  bits: 134.3 E(85289): 3.2e-31
Smith-Waterman score: 1530; 94.8% identity (96.0% similar) in 252 aa overlap (1-252:1-250)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::  .  
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMA--ETT
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
       :   . : . ::                                                
XP_016 GDSATCQIEPWSSL                                              
      240       250                                                

>>XP_006722862 (OMIM: 601263,615280) PREDICTED: dual spe  (307 aa)
 initn: 1528 init1: 1528 opt: 1528  Z-score: 680.0  bits: 134.3 E(85289): 3.9e-31
Smith-Waterman score: 1821; 76.8% identity (76.8% similar) in 400 aa overlap (1-400:1-307)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_006 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAP----
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
                                                                   
XP_006 ------------------------------------------------------------
                                                                   

              310       320       330       340       350       360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
                                    :::::::::::::::::::::::::::::::
XP_006 -----------------------------PPKLPNGVFTPDFQEFVNKCLIKNPAERADL
                                     240       250       260       

              370       380       390       400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
       ::::::::::::::::::::::::::::::::::::::::
XP_006 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
       270       280       290       300       

>>XP_016882479 (OMIM: 601263,615280) PREDICTED: dual spe  (419 aa)
 initn: 1561 init1: 1528 opt: 1528  Z-score: 678.8  bits: 134.5 E(85289): 4.6e-31
Smith-Waterman score: 1528; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236)

               10        20        30        40        50        60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPPPKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
                                                                   
XP_016 PNGVFTPDFQEFVNKWFWEGRQPHSILLPPSTQQHLWRGLHRHVPQTTGKELRTPRCPQG
              250       260       270       280       290       300

>>XP_016877902 (OMIM: 163950,176872,615279) PREDICTED: d  (217 aa)
 initn: 1142 init1: 595 opt: 1135  Z-score: 515.2  bits: 103.3 E(85289): 5.9e-22
Smith-Waterman score: 1135; 80.3% identity (91.3% similar) in 208 aa overlap (192-399:12-215)

             170       180       190       200       210       220 
pF1KB6 AKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLID
                                     ...:::::::::::::::::::::::::::
XP_016                    MVPVHQQFLSKQHNVKPSNILVNSRGEIKLCDFGVSGQLID
                                  10        20        30        40 

             230       240       250       260       270       280 
pF1KB6 SMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGR
       :::::::::::::.::::::::::::::::::::::::.:::::::::::::::: .:: 
XP_016 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC
              50        60        70        80        90       100 

             290       300       310       320       330       340 
pF1KB6 PVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPD
        :    ::.     :::: ::::.:..:::::: :::::::::::::::::::.:::. .
XP_016 QV----EGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLE
                 110       120       130       140       150       

             350       360       370       380       390       400 
pF1KB6 FQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV 
       ::.:::::::::::::::::.:  :.:::::..::::::::::.:. ::::.:::..:  
XP_016 FQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
       160       170       180       190       200       210       

>>NP_001193733 (OMIM: 602520) dual specificity mitogen-a  (412 aa)
 initn: 712 init1: 388 opt: 781  Z-score: 363.1  bits: 76.1 E(85289): 1.7e-13
Smith-Waterman score: 863; 40.6% identity (68.3% similar) in 347 aa overlap (52-395:110-412)

              30        40        50        60        70        80 
pF1KB6 PSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAG
                                     :.  : : .    :.....:..  . :: :
NP_001 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
      80        90       100       110       120       130         

              90       100       110       120       130       140 
pF1KB6 NGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
       :::.: :. : ::: :.: :.: :.:   ...::. ::..:..:.: ::.::::::. ..
NP_001 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
     140       150       160       170       180       190         

             150       160       170       180       190       200 
pF1KB6 EISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNIL
       .:::: : :::::::      ...::..::....::..::.::  . .:.::::::::.:
NP_001 RISICTEFMDGGSLDVY----RKMPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
     200       210           220       230        240       250    

             210       220       230       240       250       260 
pF1KB6 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELA
       ::.::..:::::::: ::..:.:...::: .::::::..: .:...::.::.:.:..:::
NP_001 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
          260       270       280       290       300       310    

             270       280       290       300       310       320 
pF1KB6 VGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFEL
       .::.: :               .. ..:   :. :                      ..:
NP_001 LGRFPYPQ--------------IQKNQG---SLMP----------------------LQL
          320                        330                           

             330       340       350       360        370       380
pF1KB6 LDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFI-KRSEVEEVDFA
       :. ::.:  : :: : :.  : .:...:. :.: ::   . : .: :: . .. . .  .
NP_001 LQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS
         340       350       360       370       380       390     

                390       400
pF1KB6 GWLCKTL--RLNQPGTPTRTAV
        :.:..:  : .: : :     
NP_001 MWVCRALEERRSQQGPP     
         400       410       

>>NP_660143 (OMIM: 602520) dual specificity mitogen-acti  (448 aa)
 initn: 712 init1: 388 opt: 781  Z-score: 362.8  bits: 76.2 E(85289): 1.8e-13
Smith-Waterman score: 863; 40.6% identity (68.3% similar) in 347 aa overlap (52-395:146-448)

              30        40        50        60        70        80 
pF1KB6 PSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAG
                                     :.  : : .    :.....:..  . :: :
NP_660 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
         120       130       140       150       160       170     

              90       100       110       120       130       140 
pF1KB6 NGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
       :::.: :. : ::: :.: :.: :.:   ...::. ::..:..:.: ::.::::::. ..
NP_660 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
         180       190       200       210       220       230     

             150       160       170       180       190       200 
pF1KB6 EISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNIL
       .:::: : :::::::      ...::..::....::..::.::  . .:.::::::::.:
NP_660 RISICTEFMDGGSLDVY----RKMPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
         240       250           260       270        280       290

             210       220       230       240       250       260 
pF1KB6 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELA
       ::.::..:::::::: ::..:.:...::: .::::::..: .:...::.::.:.:..:::
NP_660 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
              300       310       320       330       340       350

             270       280       290       300       310       320 
pF1KB6 VGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFEL
       .::.: :               .. ..:   :. :                      ..:
NP_660 LGRFPYPQ--------------IQKNQG---SLMP----------------------LQL
                            360                                370 

             330       340       350       360        370       380
pF1KB6 LDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFI-KRSEVEEVDFA
       :. ::.:  : :: : :.  : .:...:. :.: ::   . : .: :: . .. . .  .
NP_660 LQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS
             380       390       400       410       420       430 

                390       400
pF1KB6 GWLCKTL--RLNQPGTPTRTAV
        :.:..:  : .: : :     
NP_660 MWVCRALEERRSQQGPP     
             440             




400 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:07:30 2016 done: Sat Nov  5 01:07:32 2016
 Total Scan time:  8.710 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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