Result of FASTA (omim) for pF1KE0507
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0507, 259 aa
  1>>>pF1KE0507 259 - 259 aa - 259 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2928+/-0.000274; mu= 15.8022+/- 0.017
 mean_var=77.2498+/-15.572, 0's: 0 Z-trim(120.2): 67  B-trim: 566 in 1/53
 Lambda= 0.145924
 statistics sampled from 34966 (35039) to 34966 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.411), width:  16
 Scan time:  6.790

The best scores are:                                      opt bits E(85289)
XP_005261430 (OMIM: 614240) PREDICTED: sesquipedal ( 259) 1799 387.4 1.4e-107
NP_001002034 (OMIM: 614240) sesquipedalian-2 [Homo ( 259) 1799 387.4 1.4e-107
XP_016874372 (OMIM: 614239) PREDICTED: sesquipedal ( 249)  482 110.1   4e-24
NP_001171468 (OMIM: 614239) sesquipedalian-1 isofo ( 249)  482 110.1   4e-24
XP_011536278 (OMIM: 614239) PREDICTED: sesquipedal ( 249)  482 110.1   4e-24
XP_006719320 (OMIM: 614239) PREDICTED: sesquipedal ( 249)  482 110.1   4e-24
NP_653272 (OMIM: 614239) sesquipedalian-1 isoform  ( 249)  482 110.1   4e-24
NP_001171467 (OMIM: 614239) sesquipedalian-1 isofo ( 262)  482 110.1 4.1e-24


>>XP_005261430 (OMIM: 614240) PREDICTED: sesquipedalian-  (259 aa)
 initn: 1799 init1: 1799 opt: 1799  Z-score: 2052.3  bits: 387.4 E(85289): 1.4e-107
Smith-Waterman score: 1799; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
              190       200       210       220       230       240

              250         
pF1KE0 CWQKRAQGSHSKCEEQDRP
       :::::::::::::::::::
XP_005 CWQKRAQGSHSKCEEQDRP
              250         

>>NP_001002034 (OMIM: 614240) sesquipedalian-2 [Homo sap  (259 aa)
 initn: 1799 init1: 1799 opt: 1799  Z-score: 2052.3  bits: 387.4 E(85289): 1.4e-107
Smith-Waterman score: 1799; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQ
              190       200       210       220       230       240

              250         
pF1KE0 CWQKRAQGSHSKCEEQDRP
       :::::::::::::::::::
NP_001 CWQKRAQGSHSKCEEQDRP
              250         

>>XP_016874372 (OMIM: 614239) PREDICTED: sesquipedalian-  (249 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 554.1  bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       :::::::.: ::  :.:.:. :::   ::       ..  :: ::::.::.:: ::.  .
XP_016 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
               10        20             30         40        50    

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       : :.....::::::::.::   ::::::. : .  .: ..::::.  :.:.:::.:::::
XP_016 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
           60        70          80        90       100       110  

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       : :.::::::::.::  .: . ..    .  .   .  :  :.  .: :     : .  .
XP_016 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
            120       130           140       150        160       

              190           200               210        220       
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
       ::  .      ::      : : :  ..        :      ....: .: . . :. :
XP_016 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
       170       180       190       200       210       220       

       230       240        250         
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       :. :::::  ::  : ..:.:            
XP_016 HECYGQEIRALRGQWLSSRVQP           
       230       240                    

>>NP_001171468 (OMIM: 614239) sesquipedalian-1 isoform 2  (249 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 554.1  bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       :::::::.: ::  :.:.:. :::   ::       ..  :: ::::.::.:: ::.  .
NP_001 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
               10        20             30         40        50    

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       : :.....::::::::.::   ::::::. : .  .: ..::::.  :.:.:::.:::::
NP_001 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
           60        70          80        90       100       110  

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       : :.::::::::.::  .: . ..    .  .   .  :  :.  .: :     : .  .
NP_001 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
            120       130           140       150        160       

              190           200               210        220       
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
       ::  .      ::      : : :  ..        :      ....: .: . . :. :
NP_001 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
       170       180       190       200       210       220       

       230       240        250         
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       :. :::::  ::  : ..:.:            
NP_001 HECYGQEIRALRGQWLSSRVQP           
       230       240                    

>>XP_011536278 (OMIM: 614239) PREDICTED: sesquipedalian-  (249 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 554.1  bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       :::::::.: ::  :.:.:. :::   ::       ..  :: ::::.::.:: ::.  .
XP_011 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
               10        20             30         40        50    

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       : :.....::::::::.::   ::::::. : .  .: ..::::.  :.:.:::.:::::
XP_011 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
           60        70          80        90       100       110  

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       : :.::::::::.::  .: . ..    .  .   .  :  :.  .: :     : .  .
XP_011 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
            120       130           140       150        160       

              190           200               210        220       
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
       ::  .      ::      : : :  ..        :      ....: .: . . :. :
XP_011 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
       170       180       190       200       210       220       

       230       240        250         
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       :. :::::  ::  : ..:.:            
XP_011 HECYGQEIRALRGQWLSSRVQP           
       230       240                    

>>XP_006719320 (OMIM: 614239) PREDICTED: sesquipedalian-  (249 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 554.1  bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       :::::::.: ::  :.:.:. :::   ::       ..  :: ::::.::.:: ::.  .
XP_006 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
               10        20             30         40        50    

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       : :.....::::::::.::   ::::::. : .  .: ..::::.  :.:.:::.:::::
XP_006 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
           60        70          80        90       100       110  

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       : :.::::::::.::  .: . ..    .  .   .  :  :.  .: :     : .  .
XP_006 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
            120       130           140       150        160       

              190           200               210        220       
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
       ::  .      ::      : : :  ..        :      ....: .: . . :. :
XP_006 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
       170       180       190       200       210       220       

       230       240        250         
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       :. :::::  ::  : ..:.:            
XP_006 HECYGQEIRALRGQWLSSRVQP           
       230       240                    

>>NP_653272 (OMIM: 614239) sesquipedalian-1 isoform 2 [H  (249 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 554.1  bits: 110.1 E(85289): 4e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:1-248)

               10        20        30        40        50        60
pF1KE0 MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREG
       :::::::.: ::  :.:.:. :::   ::       ..  :: ::::.::.:: ::.  .
NP_653 MKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVLRGNMLFYFEDAAS
               10        20             30         40        50    

               70        80        90       100       110       120
pF1KE0 RAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRAS
       : :.....::::::::.::   ::::::. : .  .: ..::::.  :.:.:::.:::::
NP_653 REPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS
           60        70          80        90       100       110  

              130       140       150       160       170       180
pF1KE0 FGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSS
       : :.::::::::.::  .: . ..    .  .   .  :  :.  .: :     : .  .
NP_653 FDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA-LAPVPSLPSAPA
            120       130           140       150        160       

              190           200               210        220       
pF1KE0 PVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQSPVSP-ETSCFSTL
       ::  .      ::      : : :  ..        :      ....: .: . . :. :
NP_653 PVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPLDMAPFARL
       170       180       190       200       210       220       

       230       240        250         
pF1KE0 HDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       :. :::::  ::  : ..:.:            
NP_653 HECYGQEIRALRGQWLSSRVQP           
       230       240                    

>>NP_001171467 (OMIM: 614239) sesquipedalian-1 isoform 1  (262 aa)
 initn: 522 init1: 211 opt: 482  Z-score: 553.8  bits: 110.1 E(85289): 4.1e-24
Smith-Waterman score: 484; 40.2% identity (60.5% similar) in 261 aa overlap (1-247:14-261)

                            10        20        30        40       
pF1KE0              MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVL
                    :::::::.: ::  :.:.:. :::   ::       ..  :: ::::
NP_001 MAPGSPPGPAIATMKLNERSLAFYATCDAPVDNAGFLYKKGG-----RHAAYHRR-WFVL
               10        20        30        40             50     

        50        60        70        80        90       100       
pF1KE0 KGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPA
       .::.:: ::.  .: :.....::::::::.::   ::::::. : .  .: ..::::.  
NP_001 RGNMLFYFEDAASREPVGVIILEGCTVELVEAA--EEFAFAVRFAGTRARTYVLAAESQD
           60        70        80          90       100       110  

       110       120       130       140       150       160       
pF1KE0 AQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAA
       :.:.:::.:::::: :.::::::::.::  .: . ..    .  .   .  :  :.  .:
NP_001 AMEGWVKALSRASFDYLRLVVRELEQQLAAVRGGGGM----ALPQPQPQSLPLPPSLPSA
            120       130       140           150       160        

       170       180       190           200               210     
pF1KE0 GLENGHCLSKDSSPVGLVEEAGSRSA----GWGLAEWELQG--------PASLLLGKGQS
        :     : .  .::  .      ::      : : :  ..        :      ....
NP_001 -LAPVPSLPSAPAPVPALPLPRRPSALPPKENGCAVWSTEATFRPGPEPPPPPPRRRASA
       170       180       190       200       210       220       

          220       230       240        250         
pF1KE0 PVSP-ETSCFSTLHDWYGQEIVELRQCW-QKRAQGSHSKCEEQDRP
       : .: . . :. ::. :::::  ::  : ..:.:            
NP_001 PHGPLDMAPFARLHECYGQEIRALRGQWLSSRVQP           
       230       240       250       260             




259 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 03:43:18 2016 done: Thu Nov  3 03:43:19 2016
 Total Scan time:  6.790 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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