Result of FASTA (omim) for pF1KE0137
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0137, 172 aa
  1>>>pF1KE0137 172 - 172 aa - 172 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0737+/-0.000408; mu= 10.8202+/- 0.026
 mean_var=141.3394+/-29.002, 0's: 0 Z-trim(116.7): 161  B-trim: 729 in 2/51
 Lambda= 0.107880
 statistics sampled from 27769 (28008) to 27769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.328), width:  16
 Scan time:  5.270

The best scores are:                                      opt bits E(85289)
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens]  ( 172) 1087 179.9 1.7e-45
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens]  ( 172)  961 160.3 1.4e-39
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167)  601 104.3   1e-22
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191)  570 99.5 3.1e-21
NP_008819 (OMIM: 114180,614916,616247) calmodulin  ( 149)  496 87.9 7.7e-18
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149)  496 87.9 7.7e-18
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149)  496 87.9 7.7e-18
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149)  496 87.9 7.7e-18
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150)  496 87.9 7.8e-18
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197)  496 88.0 9.3e-18
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149)  478 85.1 5.4e-17
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160)  402 73.3 2.1e-13
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145)  387 70.9 9.7e-13
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113)  374 68.7 3.4e-12
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  374 68.7 3.4e-12
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  374 68.7 3.4e-12
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  374 68.7 3.4e-12
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  374 68.7 3.4e-12
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  374 68.7 3.4e-12
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113)  374 68.7 3.4e-12
NP_001284697 (OMIM: 602907) centrin-3 isoform 3 [H ( 153)  375 69.0 3.7e-12
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161)  365 67.5 1.1e-11
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146)  352 65.4 4.3e-11
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164)  314 59.6 2.8e-09
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173)  312 59.3 3.6e-09
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181)  310 59.0 4.6e-09
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203)  310 59.1 4.9e-09
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284)  312 59.6 4.9e-09
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227)  293 56.5 3.3e-08
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167)  291 56.0 3.4e-08
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172)  291 56.0 3.4e-08
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370)  289 56.1   7e-08
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220)  285 55.2 7.7e-08
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226)  285 55.2 7.8e-08
XP_011543485 (OMIM: 608965,610427) PREDICTED: calc ( 170)  281 54.5   1e-07
NP_001287825 (OMIM: 608965,610427) calcium-binding ( 170)  281 54.5   1e-07
XP_016873514 (OMIM: 608965,610427) PREDICTED: calc ( 170)  281 54.5   1e-07
NP_001287824 (OMIM: 608965,610427) calcium-binding ( 170)  281 54.5   1e-07
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172)  280 54.3 1.1e-07
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172)  280 54.3 1.1e-07
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172)  280 54.3 1.1e-07
NP_660201 (OMIM: 608965,610427) calcium-binding pr ( 275)  281 54.7 1.4e-07
XP_011543483 (OMIM: 608965,610427) PREDICTED: calc ( 295)  281 54.7 1.4e-07
XP_016875727 (OMIM: 605563) PREDICTED: calcium-bin ( 262)  272 53.3 3.5e-07
XP_016875728 (OMIM: 605563) PREDICTED: calcium-bin ( 202)  270 52.8 3.7e-07
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173)  266 52.1 5.1e-07
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173)  266 52.1 5.1e-07
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173)  266 52.1 5.1e-07
XP_016875724 (OMIM: 605563) PREDICTED: calcium-bin ( 405)  268 52.9 7.2e-07
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328)  266 52.5 7.8e-07


>>NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens]       (172 aa)
 initn: 1087 init1: 1087 opt: 1087  Z-score: 937.6  bits: 179.9 E(85289): 1.7e-45
Smith-Waterman score: 1087; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
               70        80        90       100       110       120

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
              130       140       150       160       170  

>>NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens]       (172 aa)
 initn: 961 init1: 961 opt: 961  Z-score: 831.6  bits: 160.3 E(85289): 1.4e-39
Smith-Waterman score: 961; 83.7% identity (98.8% similar) in 172 aa overlap (1-172:1-172)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
       :::.::: . ::..:.....:::::::.::::.::::::::.::.::::.::::::::::
NP_004 MASGFKKPSAASTGQKRKVAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       ::::.:::.::::::.:.:::::..:.:::.:::::::::::::::::::.:::::::::
NP_004 GFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGK
               70        80        90       100       110       120

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::::::::::.::::::::::::::::::::::::::.:.::::::::::::
NP_004 ISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY
              130       140       150       160       170  

>>NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo sap  (167 aa)
 initn: 595 init1: 595 opt: 601  Z-score: 529.0  bits: 104.3 E(85289): 1e-22
Smith-Waterman score: 601; 54.2% identity (84.9% similar) in 166 aa overlap (1-166:1-163)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
       :.  ...  ......::.   . ::.:::::::..::.:::.:   .:: .:::::::::
NP_004 MSLALRSELVVDKTKRKK---RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRAL
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       ::. :: .. :.... :.:.:::..: ::  :.:. . :.: .:::::::::::::..::
NP_004 GFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGK
        60        70        80        90       100       110       

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::..::.:::.:::::..::::. ::.: :.:::::....::. ::      
NP_004 ISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI  
       120       130       140       150       160         

>>NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [Homo   (191 aa)
 initn: 667 init1: 562 opt: 570  Z-score: 502.2  bits: 99.5 E(85289): 3.1e-21
Smith-Waterman score: 570; 54.8% identity (84.7% similar) in 157 aa overlap (1-157:1-154)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
       :.  ...  ......::.   . ::.:::::::..::.:::.:   .:: .:::::::::
NP_001 MSLALRSELVVDKTKRKK---RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRAL
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       ::. :: .. :.... :.:.:::..: ::  :.:. . :.: .:::::::::::::..::
NP_001 GFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGK
        60        70        80        90       100       110       

              130       140       150       160       170          
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY        
       ::..::.:::.:::::..::::. ::.: :.:::::.                       
NP_001 ISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEILKNILLLPIWSRCLSLNREFFSE
       120       130       140       150       160       170       

NP_001 VNQEEFIAIMTGDI
       180       190 

>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom  (149 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 441.2  bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
                              .:::::  :..:::.::: :: ::: .::: ..::.:
NP_008                     MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: 
NP_008 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
               50        60        70        80        90       100

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
NP_008 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
              110       120       130       140            

>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo  (149 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 441.2  bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
                              .:::::  :..:::.::: :: ::: .::: ..::.:
NP_001                     MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: 
NP_001 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
               50        60        70        80        90       100

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
NP_001 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
              110       120       130       140            

>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa  (149 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 441.2  bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
                              .:::::  :..:::.::: :: ::: .::: ..::.:
NP_005                     MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: 
NP_005 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
               50        60        70        80        90       100

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
NP_005 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
              110       120       130       140            

>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [  (149 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 441.2  bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
                              .:::::  :..:::.::: :: ::: .::: ..::.:
NP_001                     MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: 
NP_001 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
               50        60        70        80        90       100

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
NP_001 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
              110       120       130       140            

>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c  (150 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 441.2  bits: 87.9 E(85289): 7.8e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:5-147)

               10        20        30        40        50        60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
                              .:::::  :..:::.::: :: ::: .::: ..::.:
XP_006                    MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
                                  10        20        30        40 

               70        80        90       100       110       120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
       : .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .: 
XP_006 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
              50        60        70        80        90       100 

              130       140       150       160       170  
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
XP_006 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
             110       120       130       140       150   

>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform   (197 aa)
 initn: 797 init1: 494 opt: 496  Z-score: 439.8  bits: 88.0 E(85289): 9.3e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:52-194)

                      10        20        30        40        50   
pF1KE0        MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKEL
                                     .:::::  :..:::.::: :: ::: .:::
NP_001 VVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL
              30        40        50        60        70        80 

            60        70        80        90       100       110   
pF1KE0 KVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLF
        ..::.:: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:
NP_001 GTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVF
              90       100       110       120       130       140 

           120       130       140       150       160       170  
pF1KE0 DDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
       : : .: ::  .:..:  .:::.:::::..::: ::: ::::.:. .::...:      
NP_001 DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK   
             150       160       170       180       190          




172 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:03:23 2016 done: Fri Nov  4 01:03:24 2016
 Total Scan time:  5.270 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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