Result of FASTA (omim) for pF1KE0032
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0032, 607 aa
  1>>>pF1KE0032 607 - 607 aa - 607 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8294+/-0.000312; mu= 18.1248+/- 0.020
 mean_var=93.6973+/-19.072, 0's: 0 Z-trim(118.0): 108  B-trim: 0 in 0/52
 Lambda= 0.132498
 statistics sampled from 30454 (30565) to 30454 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.358), width:  16
 Scan time: 11.840

The best scores are:                                      opt bits E(85289)
NP_932327 (OMIM: 605278) cocaine esterase isoform  ( 607) 4132 800.1       0
NP_003860 (OMIM: 605278) cocaine esterase isoform  ( 623) 3534 685.7 1.2e-196
XP_016879307 (OMIM: 605278) PREDICTED: cocaine est ( 450) 3041 591.4 2.2e-168
XP_011521723 (OMIM: 605278) PREDICTED: cocaine est ( 466) 2443 477.1 5.8e-134
NP_001172106 (OMIM: 605279) carboxylesterase 3 iso ( 568) 1385 274.9 5.1e-73
NP_079198 (OMIM: 605279) carboxylesterase 3 isofor ( 571) 1385 274.9 5.1e-73
XP_011521277 (OMIM: 605279) PREDICTED: carboxylest ( 547) 1368 271.7 4.7e-72
XP_011521278 (OMIM: 605279) PREDICTED: carboxylest ( 402) 1146 229.1 2.2e-59
NP_001257 (OMIM: 114835) liver carboxylesterase 1  ( 566) 1049 210.7 1.1e-53
NP_001020365 (OMIM: 114835) liver carboxylesterase ( 567) 1049 210.7 1.1e-53
XP_005255831 (OMIM: 114835) PREDICTED: liver carbo ( 567) 1049 210.7 1.1e-53
NP_001020366 (OMIM: 114835) liver carboxylesterase ( 568) 1049 210.7 1.1e-53
XP_016885526 (OMIM: 400028) PREDICTED: neuroligin- ( 816)  743 152.3 5.9e-36
XP_016885527 (OMIM: 400028) PREDICTED: neuroligin- ( 816)  743 152.3 5.9e-36
XP_016885524 (OMIM: 400028) PREDICTED: neuroligin- ( 816)  743 152.3 5.9e-36
XP_016885523 (OMIM: 400028) PREDICTED: neuroligin- ( 816)  743 152.3 5.9e-36
NP_055708 (OMIM: 400028) neuroligin-4, Y-linked is ( 816)  743 152.3 5.9e-36
XP_016885525 (OMIM: 400028) PREDICTED: neuroligin- ( 816)  743 152.3 5.9e-36
NP_001269075 (OMIM: 300427,300495,300497) neurolig ( 816)  735 150.8 1.7e-35
NP_001269074 (OMIM: 300427,300495,300497) neurolig ( 816)  735 150.8 1.7e-35
NP_065793 (OMIM: 300427,300495,300497) neuroligin- ( 816)  735 150.8 1.7e-35
XP_016885180 (OMIM: 300427,300495,300497) PREDICTE ( 816)  735 150.8 1.7e-35
NP_851849 (OMIM: 300427,300495,300497) neuroligin- ( 816)  735 150.8 1.7e-35
XP_016885181 (OMIM: 300427,300495,300497) PREDICTE ( 816)  735 150.8 1.7e-35
XP_016885182 (OMIM: 300427,300495,300497) PREDICTE ( 816)  735 150.8 1.7e-35
XP_005256801 (OMIM: 606479) PREDICTED: neuroligin- ( 818)  730 149.8 3.3e-35
XP_016867709 (OMIM: 100740,112100) PREDICTED: acet ( 692)  727 149.2 4.3e-35
XP_011514528 (OMIM: 100740,112100) PREDICTED: acet ( 695)  727 149.2 4.4e-35
XP_016867708 (OMIM: 100740,112100) PREDICTED: acet ( 780)  726 149.1 5.4e-35
XP_011514527 (OMIM: 100740,112100) PREDICTED: acet ( 783)  726 149.1 5.4e-35
NP_001269378 (OMIM: 100740,112100) acetylcholinest ( 526)  723 148.4   6e-35
NP_001289551 (OMIM: 100740,112100) acetylcholinest ( 614)  722 148.2 7.7e-35
NP_000656 (OMIM: 100740,112100) acetylcholinestera ( 614)  722 148.2 7.7e-35
NP_001289550 (OMIM: 100740,112100) acetylcholinest ( 617)  722 148.2 7.7e-35
XP_011514531 (OMIM: 100740,112100) PREDICTED: acet ( 617)  722 148.2 7.7e-35
NP_056646 (OMIM: 100740,112100) acetylcholinestera ( 617)  722 148.2 7.7e-35
XP_011514530 (OMIM: 100740,112100) PREDICTED: acet ( 617)  722 148.2 7.7e-35
XP_006716058 (OMIM: 100740,112100) PREDICTED: acet ( 617)  722 148.2 7.7e-35
XP_016861391 (OMIM: 600568) PREDICTED: neuroligin- ( 814)  716 147.2 2.1e-34
XP_016861393 (OMIM: 600568) PREDICTED: neuroligin- ( 814)  716 147.2 2.1e-34
XP_005247293 (OMIM: 600568) PREDICTED: neuroligin- ( 814)  716 147.2 2.1e-34
XP_016861392 (OMIM: 600568) PREDICTED: neuroligin- ( 814)  716 147.2 2.1e-34
NP_001160132 (OMIM: 300336,300425,300494) neurolig ( 808)  700 144.1 1.7e-33
NP_000046 (OMIM: 177400) cholinesterase precursor  ( 602)  695 143.0 2.7e-33
XP_016862456 (OMIM: 177400) PREDICTED: cholinester ( 643)  695 143.1 2.8e-33
XP_005274621 (OMIM: 300427,300495,300497) PREDICTE ( 836)  665 137.4 1.9e-31
XP_005274623 (OMIM: 300427,300495,300497) PREDICTE ( 836)  665 137.4 1.9e-31
XP_011543850 (OMIM: 300427,300495,300497) PREDICTE ( 836)  665 137.4 1.9e-31
XP_016885179 (OMIM: 300427,300495,300497) PREDICTE ( 836)  665 137.4 1.9e-31
XP_006724567 (OMIM: 300427,300495,300497) PREDICTE ( 836)  665 137.4 1.9e-31


>>NP_932327 (OMIM: 605278) cocaine esterase isoform 2 [H  (607 aa)
 initn: 4132 init1: 4132 opt: 4132  Z-score: 4269.4  bits: 800.1 E(85289):    0
Smith-Waterman score: 4132; 100.0% identity (100.0% similar) in 607 aa overlap (1-607:1-607)

               10        20        30        40        50        60
pF1KE0 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 NFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 NFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEP
              550       560       570       580       590       600

              
pF1KE0 EERHTEL
       :::::::
NP_932 EERHTEL
              

>>NP_003860 (OMIM: 605278) cocaine esterase isoform 1 [H  (623 aa)
 initn: 3534 init1: 3534 opt: 3534  Z-score: 3651.5  bits: 685.7 E(85289): 1.2e-196
Smith-Waterman score: 4089; 97.3% identity (97.4% similar) in 623 aa overlap (1-607:1-623)

               10        20        30        40        50        60
pF1KE0 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTET
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMF
              430       440       450       460       470       480

              490       500       510       520                    
pF1KE0 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH----------------VKF
       :::::::::::::::::::::::::::::::::::::::::                .::
NP_003 VIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKF
              490       500       510       520       530       540

          530       540       550       560       570       580    
pF1KE0 TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQ
              550       560       570       580       590       600

          590       600       
pF1KE0 FWKKALPQKIQELEEPEERHTEL
       :::::::::::::::::::::::
NP_003 FWKKALPQKIQELEEPEERHTEL
              610       620   

>>XP_016879307 (OMIM: 605278) PREDICTED: cocaine esteras  (450 aa)
 initn: 3041 init1: 3041 opt: 3041  Z-score: 3144.1  bits: 591.4 E(85289): 2.2e-168
Smith-Waterman score: 3041; 100.0% identity (100.0% similar) in 450 aa overlap (158-607:1-450)

       130       140       150       160       170       180       
pF1KE0 AKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDC
                                     ::::::::::::::::::::::::::::::
XP_016                               MCLQDLTAVESEFLSQFNMTFPSDSMSEDC
                                             10        20        30

       190       200       210       220       230       240       
pF1KE0 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLG
               40        50        60        70        80        90

       250       260       270       280       290       300       
pF1KE0 FFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPIS
              100       110       120       130       140       150

       310       320       330       340       350       360       
pF1KE0 QGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAI
              160       170       180       190       200       210

       370       380       390       400       410       420       
pF1KE0 NKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEM
              220       230       240       250       260       270

       430       440       450       460       470       480       
pF1KE0 DREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQV
              280       290       300       310       320       330

       490       500       510       520       530       540       
pF1KE0 AHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGN
              340       350       360       370       380       390

       550       560       570       580       590       600       
pF1KE0 PNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL
              400       410       420       430       440       450

>>XP_011521723 (OMIM: 605278) PREDICTED: cocaine esteras  (466 aa)
 initn: 2443 init1: 2443 opt: 2443  Z-score: 2526.1  bits: 477.1 E(85289): 5.8e-134
Smith-Waterman score: 2998; 96.4% identity (96.6% similar) in 466 aa overlap (158-607:1-466)

       130       140       150       160       170       180       
pF1KE0 AKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDC
                                     ::::::::::::::::::::::::::::::
XP_011                               MCLQDLTAVESEFLSQFNMTFPSDSMSEDC
                                             10        20        30

       190       200       210       220       230       240       
pF1KE0 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLG
               40        50        60        70        80        90

       250       260       270       280       290       300       
pF1KE0 FFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPIS
              100       110       120       130       140       150

       310       320       330       340       350       360       
pF1KE0 QGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAI
              160       170       180       190       200       210

       370       380       390       400       410       420       
pF1KE0 NKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEM
              220       230       240       250       260       270

       430       440       450       460       470       480       
pF1KE0 DREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQV
              280       290       300       310       320       330

       490       500       510       520                       530 
pF1KE0 AHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH----------------VKFTEEEEQL
       ::::::::::::::::::::::::::::::::::                .:::::::::
XP_011 AHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQL
              340       350       360       370       380       390

             540       550       560       570       580       590 
pF1KE0 SRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALP
              400       410       420       430       440       450

             600       
pF1KE0 QKIQELEEPEERHTEL
       ::::::::::::::::
XP_011 QKIQELEEPEERHTEL
              460      

>>NP_001172106 (OMIM: 605279) carboxylesterase 3 isoform  (568 aa)
 initn: 1462 init1: 707 opt: 1385  Z-score: 1431.9  bits: 274.9 E(85289): 5.1e-73
Smith-Waterman score: 1616; 46.3% identity (70.7% similar) in 553 aa overlap (74-602:12-560)

            50        60        70        80        90       100   
pF1KE0 GQPLGEQQRVRRQRTETSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTG
                                     : .:.: ::   . . : . :.:   :  :
NP_001                    MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLG
                                  10        20        30        40 

           110       120       130       140       150       160   
pF1KE0 QVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDL
       .: :  : :::..  :..:::::::.::::: ::. :.: . : ::::..: : :::::.
NP_001 RVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDV
              50        60        70        80        90       100 

           170       180         190       200       210       220 
pF1KE0 TAVESEFLSQFNMTFPSD--SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMAS
        ...:   :.: ..  ..  :.::::: :..:.::.   ::. :::::.:::::. : :.
NP_001 ESMNS---SRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAAT
                110       120       130       140       150        

             230       240       250       260       270       280 
pF1KE0 LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGG
        :::: :::  .:::: .::::::::::::::.:: :: :.:: ::::::::.::: :::
NP_001 SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGG
      160       170       180       190       200       210        

             290       300       310       320       330       340 
pF1KE0 NPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL
       . . ::.:: ::::. .:.::.::.. :::: :: .:::   ::.: :    ..  .:: 
NP_001 DLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANT
      220       230       240       250       260       270        

             350       360       370         380       390         
pF1KE0 SACDQVDSEALVGCLRGKSKEEILAINKPFK--MIPGVVDGVFLPRHPQELLASADFQPV
        ::.. .   .: ::. :  :: :...: .:  . : .:::. .:. :.:::    :. :
NP_001 LACSSSSPAEMVQCLQQKEGEE-LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSV
      280       290       300        310       320       330       

     400       410       420       430       440       450         
pF1KE0 PSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIG
       : ..::::.::.::::.   . ::...:.::   :    .:: : .:: .   . .::.:
NP_001 PFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLG
       340       350       360       370       380       390       

     460       470       480       490        500       510        
pF1KE0 DNGDPQTLQAQFQEMMADSMFVIPALQVAHF-QCSRAPVYFYEFQHQPSWLKNIRPPHMK
       .:.: :.    :::.:.: .. .:... ... . : .::.::::::.:: . .:.:  .:
NP_001 SNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK
       400       410       420       430       440       450       

      520                          530       540       550         
pF1KE0 ADH-------------------VKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLF
       :::                   .. ::::.:::  ::  :..:::.:.::...:: :: :
NP_001 ADHGAEGAFVFGGPFLMDESSRLEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQF
       460       470       480       490       500       510       

     560       570       580       590       600          
pF1KE0 DQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL   
       .: ::::..:  : .:. ..   .:::...::.:::. .. ..        
NP_001 NQAEQYLEINPVPRAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL
       520       530       540       550       560        

>>NP_079198 (OMIM: 605279) carboxylesterase 3 isoform 1   (571 aa)
 initn: 1462 init1: 707 opt: 1385  Z-score: 1431.9  bits: 274.9 E(85289): 5.1e-73
Smith-Waterman score: 1609; 46.2% identity (70.3% similar) in 556 aa overlap (74-602:12-563)

            50        60        70        80        90       100   
pF1KE0 GQPLGEQQRVRRQRTETSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTG
                                     : .:.: ::   . . : . :.:   :  :
NP_079                    MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLG
                                  10        20        30        40 

           110       120       130       140       150       160   
pF1KE0 QVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDL
       .: :  : :::..  :..:::::::.::::: ::. :.: . : ::::..: : :::::.
NP_079 RVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDV
              50        60        70        80        90       100 

           170       180         190       200       210       220 
pF1KE0 TAVESEFLSQFNMTFPSD--SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMAS
        ...:   :.: ..  ..  :.::::: :..:.::.   ::. :::::.:::::. : :.
NP_079 ESMNS---SRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAAT
                110       120       130       140       150        

             230       240       250       260       270       280 
pF1KE0 LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGG
        :::: :::  .:::: .::::::::::::::.:: :: :.:: ::::::::.::: :::
NP_079 SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGG
      160       170       180       190       200       210        

             290       300       310       320       330       340 
pF1KE0 NPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL
       . . ::.:: ::::. .:.::.::.. :::: :: .:::   ::.: :    ..  .:: 
NP_079 DLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANT
      220       230       240       250       260       270        

             350       360       370         380       390         
pF1KE0 SACDQVDSEALVGCLRGKSKEEILAINKPFK--MIPGVVDGVFLPRHPQELLASADFQPV
        ::.. .   .: ::. :  :: :...: .:  . : .:::. .:. :.:::    :. :
NP_079 LACSSSSPAEMVQCLQQKEGEE-LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSV
      280       290       300        310       320       330       

     400       410       420       430       440       450         
pF1KE0 PSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIG
       : ..::::.::.::::.   . ::...:.::   :    .:: : .:: .   . .::.:
NP_079 PFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLG
       340       350       360       370       380       390       

     460       470       480       490        500       510        
pF1KE0 DNGDPQTLQAQFQEMMADSMFVIPALQVAHF-QCSRAPVYFYEFQHQPSWLKNIRPPHMK
       .:.: :.    :::.:.: .. .:... ... . : .::.::::::.:: . .:.:  .:
NP_079 SNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK
       400       410       420       430       440       450       

      520                             530       540       550      
pF1KE0 ADH-------------------VKF---TEEEEQLSRKMMKYWANFARNGNPNGEGLPHW
       :::                   . :   ::::.:::  ::  :..:::.:.::...:: :
NP_079 ADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPW
       460       470       480       490       500       510       

        560       570       580       590       600          
pF1KE0 PLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL   
       : :.: ::::..:  : .:. ..   .:::...::.:::. .. ..        
NP_079 PQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL
       520       530       540       550       560       570 

>>XP_011521277 (OMIM: 605279) PREDICTED: carboxylesteras  (547 aa)
 initn: 1462 init1: 707 opt: 1368  Z-score: 1414.6  bits: 271.7 E(85289): 4.7e-72
Smith-Waterman score: 1592; 47.0% identity (70.4% similar) in 540 aa overlap (90-602:4-539)

      60        70        80        90       100       110         
pF1KE0 TSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGV
                                     : . :.:   :  :.: :  : :::..  :
XP_011                            MLCGPEVAQPEVDTTLGRVRGRQVGVKGTDRLV
                                          10        20        30   

     120       130       140       150       160       170         
pF1KE0 QTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFP
       ..:::::::.::::: ::. :.: . : ::::..: : :::::   :::   :.: ..  
XP_011 NVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQD---VESMNSSRFVLNGK
            40        50        60        70           80        90

     180         190       200       210       220       230       
pF1KE0 SD--SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVV
       ..  :.::::: :..:.::.   ::. :::::.:::::. : :. :::: :::  .::::
XP_011 QQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVV
              100       110       120       130       140       150

       240       250       260       270       280       290       
pF1KE0 IIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTS
        .::::::::::::::.:: :: :.:: ::::::::.::: :::. . ::.:: ::::. 
XP_011 TVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSI
              160       170       180       190       200       210

       300       310       320       330       340       350       
pF1KE0 VSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLR
       .:.::.::.. :::: :: .:::   ::.: :    ..  .::  ::.. .   .: ::.
XP_011 ISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQ
              220       230       240       250       260       270

       360       370         380       390       400       410     
pF1KE0 GKSKEEILAINKPFK--MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIP
        :  :: :...: .:  . : .:::. .:. :.:::    :. :: ..::::.::.::::
XP_011 QKEGEE-LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIP
               280       290       300       310       320         

         420       430       440       450       460       470     
pF1KE0 KVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMM
       .   . ::...:.::   :    .:: : .:: .   . .::.:.:.: :.    :::.:
XP_011 RGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFM
     330       340       350       360       370       380         

         480       490        500       510       520              
pF1KE0 ADSMFVIPALQVAHF-QCSRAPVYFYEFQHQPSWLKNIRPPHMKADH-------------
       .: .. .:... ... . : .::.::::::.:: . .:.:  .::::             
XP_011 GDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFL
     390       400       410       420       430       440         

                      530       540       550       560       570  
pF1KE0 ------VKF---TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQP
             . :   ::::.:::  ::  :..:::.:.::...:: :: :.: ::::..:  :
XP_011 MDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVP
     450       460       470       480       490       500         

            580       590       600          
pF1KE0 AVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL   
        .:. ..   .:::...::.:::. .. ..        
XP_011 RAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL
     510       520       530       540       

>>XP_011521278 (OMIM: 605279) PREDICTED: carboxylesteras  (402 aa)
 initn: 707 init1: 707 opt: 1146  Z-score: 1187.1  bits: 229.1 E(85289): 2.2e-59
Smith-Waterman score: 1146; 49.1% identity (70.9% similar) in 381 aa overlap (74-449:12-385)

            50        60        70        80        90       100   
pF1KE0 GQPLGEQQRVRRQRTETSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTG
                                     : .:.: ::   . . : . :.:   :  :
XP_011                    MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLG
                                  10        20        30        40 

           110       120       130       140       150       160   
pF1KE0 QVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDL
       .: :  : :::..  :..:::::::.::::: ::. :.: . : ::::..: : ::::: 
XP_011 RVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQD-
              50        60        70        80        90       100 

           170       180         190       200       210       220 
pF1KE0 TAVESEFLSQFNMTFPSD--SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMAS
         :::   :.: ..  ..  :.::::: :..:.::.   ::. :::::.:::::. : :.
XP_011 --VESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAAT
                110       120       130       140       150        

             230       240       250       260       270       280 
pF1KE0 LYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGG
        :::: :::  .:::: .::::::::::::::.:: :: :.:: ::::::::.::: :::
XP_011 SYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGG
      160       170       180       190       200       210        

             290       300       310       320       330       340 
pF1KE0 NPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANL
       . . ::.:: ::::. .:.::.::.. :::: :: .:::   ::.: :    ..  .:: 
XP_011 DLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANT
      220       230       240       250       260       270        

             350       360       370         380       390         
pF1KE0 SACDQVDSEALVGCLRGKSKEEILAINKPFK--MIPGVVDGVFLPRHPQELLASADFQPV
        ::.. .   .: ::. :  :: :...: .:  . : .:::. .:. :.:::    :. :
XP_011 LACSSSSPAEMVQCLQQKEGEE-LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSV
      280       290       300        310       320       330       

     400       410       420       430        440       450        
pF1KE0 PSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKM-LTLLMLPPTFGDLLREEYI
       : ..::::.::.::::. .   : .....  ..  .:  . :.    ::.:         
XP_011 PFLMGVNNHEFSWLIPRSL---DPSSRLQCSSAIMTLYCLNLSGPSNPPSFLSSSGLRAG
       340       350          360       370       380       390    

      460       470       480       490       500       510        
pF1KE0 GDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMK
                                                                   
XP_011 VSWIQWSR                                                    
          400                                                      

>>NP_001257 (OMIM: 114835) liver carboxylesterase 1 isof  (566 aa)
 initn: 1561 init1: 686 opt: 1049  Z-score: 1084.8  bits: 210.7 E(85289): 1.1e-53
Smith-Waterman score: 1577; 46.0% identity (69.9% similar) in 552 aa overlap (90-607:18-566)

      60        70        80        90       100       110         
pF1KE0 TSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGV
                                     :. :. :.  :  :.:::..: ..:    :
NP_001              MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPV
                            10        20        30        40       

     120       130       140       150       160         170       
pF1KE0 QTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVE--SEFLSQFNMT
         ::::::::::::::::.::.: : :: :...:..: :: ::  : .  ::.... . .
NP_001 AIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKEN
        50        60        70        80        90       100       

       180       190       200       210       220       230       
pF1KE0 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVV
       .:  ..:::::::.:::::   . . ::::::::::.:. : :: :::  ::: ::::::
NP_001 IPL-KLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVV
       110        120       130       140       150       160      

       240       250       260       270       280       290       
pF1KE0 IIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTS
        ::::::. :::::::.:. ::::.:::::::::::.::: :::::  :::::::::: :
NP_001 TIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGES
        170       180       190       200       210       220      

       300       310       320       330         340       350     
pF1KE0 VSSLVVSPISQGLFHGAIMESGVALLPGLIASSADV--ISTVVANLSACDQVDSEALVGC
       :: ::.::....::: :: ::::::   :. ...::  ..  .:  ..:  . : ..: :
NP_001 VSVLVLSPLAKNLFHRAISESGVALTSVLV-KKGDVKPLAEQIAITAGCKTTTSAVMVHC
        230       240       250        260       270       280     

         360       370                      380       390       400
pF1KE0 LRGKSKEEILAINKPFK---------------MIPGVVDGVFLPRHPQELLASADFQPVP
       :: :..::.:  .  .:               ..  :.::..: . :.:: :  .:. ::
NP_001 LRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVP
         290       300       310       320       330       340     

              410       420       430       440       450       460
pF1KE0 SIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGD
        .::.:..::::::: .:    .. ..:...... : :   :. .   .     :.:.: 
NP_001 YMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGG
         350       360       370       380       390       400     

              470       480        490       500       510         
pF1KE0 NGDPQTLQAQFQEMMADSMFVIPALQVA-HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKA
       . :    .  : ...:: :: .:.. :: . . . ::.:.::::..::. ....:  . .
NP_001 TDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIG
         410       420       430       440       450       460     

     520                     530       540       550       560     
pF1KE0 DH---------VKF-----TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQY
       ::         . :     .::: .::. .::.::::::::::::::::::: ..:.: :
NP_001 DHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGY
         470       480       490       500       510       520     

         570       580       590       600       
pF1KE0 LQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL
       ::.. .  ... :: ... :: . . .:  : . :. .: ::
NP_001 LQIGANTQAAQKLKDKEVAFWTNLFAKKAVE-KPPQTEHIEL
         530       540       550        560      

>>NP_001020365 (OMIM: 114835) liver carboxylesterase 1 i  (567 aa)
 initn: 1513 init1: 686 opt: 1049  Z-score: 1084.8  bits: 210.7 E(85289): 1.1e-53
Smith-Waterman score: 1569; 45.9% identity (70.0% similar) in 553 aa overlap (90-607:18-567)

      60        70        80        90       100       110         
pF1KE0 TSEPTMRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGV
                                     :. :. :.  :  :.:::..: ..:    :
NP_001              MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPV
                            10        20        30        40       

     120       130       140       150       160         170       
pF1KE0 QTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVE--SEFLSQFNMT
         ::::::::::::::::.::.: : :: :...:..: :: ::  : .  ::.... . .
NP_001 AIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKEN
        50        60        70        80        90       100       

       180       190       200       210       220       230       
pF1KE0 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVV
       .:  ..:::::::.:::::   . . ::::::::::.:. : :: :::  ::: ::::::
NP_001 IPL-KLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVV
       110        120       130       140       150       160      

       240       250       260       270       280       290       
pF1KE0 IIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTS
        ::::::. :::::::.:. ::::.:::::::::::.::: :::::  :::::::::: :
NP_001 TIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGES
        170       180       190       200       210       220      

       300       310       320       330         340       350     
pF1KE0 VSSLVVSPISQGLFHGAIMESGVALLPGLIASSADV--ISTVVANLSACDQVDSEALVGC
       :: ::.::....::: :: ::::::   :. ...::  ..  .:  ..:  . : ..: :
NP_001 VSVLVLSPLAKNLFHRAISESGVALTSVLV-KKGDVKPLAEQIAITAGCKTTTSAVMVHC
        230       240       250        260       270       280     

         360       370                      380       390       400
pF1KE0 LRGKSKEEILAINKPFK---------------MIPGVVDGVFLPRHPQELLASADFQPVP
       :: :..::.:  .  .:               ..  :.::..: . :.:: :  .:. ::
NP_001 LRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVP
         290       300       310       320       330       340     

              410        420       430       440       450         
pF1KE0 SIVGVNNNEFGWLIP-KVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIG
        .::.:..::::::: ..:    .. ..:...... : :   :. .   .     :.:.:
NP_001 YMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLG
         350       360       370       380       390       400     

     460       470       480        490       500       510        
pF1KE0 DNGDPQTLQAQFQEMMADSMFVIPALQVA-HFQCSRAPVYFYEFQHQPSWLKNIRPPHMK
        . :    .  : ...:: :: .:.. :: . . . ::.:.::::..::. ....:  . 
NP_001 GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVI
         410       420       430       440       450       460     

      520                     530       540       550       560    
pF1KE0 ADH---------VKF-----TEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQ
       .::         . :     .::: .::. .::.::::::::::::::::::: ..:.: 
NP_001 GDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEG
         470       480       490       500       510       520     

          570       580       590       600       
pF1KE0 YLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL
       :::.. .  ... :: ... :: . . .:  : . :. .: ::
NP_001 YLQIGANTQAAQKLKDKEVAFWTNLFAKKAVE-KPPQTEHIEL
         530       540       550        560       




607 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:24:12 2016 done: Fri Nov  4 07:24:13 2016
 Total Scan time: 11.840 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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