Result of FASTA (omim) for pF1KB0435
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0435, 448 aa
  1>>>pF1KB0435 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7380+/-0.000331; mu= 16.7891+/- 0.021
 mean_var=103.5487+/-20.748, 0's: 0 Z-trim(118.6): 58  B-trim: 964 in 1/54
 Lambda= 0.126038
 statistics sampled from 31650 (31722) to 31650 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.372), width:  16
 Scan time:  6.240

The best scores are:                                      opt bits E(85289)
NP_071731 (OMIM: 129490,224900,604095,612630) tumo ( 448) 3055 566.0 7.3e-161
XP_011508805 (OMIM: 129490,224900,604095,612630) P ( 496) 3055 566.0 7.9e-161
XP_006712267 (OMIM: 129490,224900,604095,612630) P ( 480) 1559 294.0 5.9e-79
XP_011508804 (OMIM: 129490,224900,604095,612630) P ( 528) 1559 294.0 6.3e-79
XP_016876141 (OMIM: 606122) PREDICTED: tumor necro ( 328)  262 58.0 4.4e-08
XP_005266503 (OMIM: 606122) PREDICTED: tumor necro ( 328)  262 58.0 4.4e-08
NP_001191387 (OMIM: 606122) tumor necrosis factor  ( 417)  262 58.1 5.3e-08
NP_683760 (OMIM: 606122) tumor necrosis factor rec ( 417)  262 58.1 5.3e-08
XP_005266502 (OMIM: 606122) PREDICTED: tumor necro ( 423)  262 58.1 5.3e-08
XP_016876140 (OMIM: 606122) PREDICTED: tumor necro ( 423)  262 58.1 5.3e-08
XP_011533448 (OMIM: 606122) PREDICTED: tumor necro ( 423)  262 58.1 5.3e-08
NP_061117 (OMIM: 606122) tumor necrosis factor rec ( 423)  262 58.1 5.3e-08
XP_011529309 (OMIM: 300276) PREDICTED: tumor necro ( 144)  250 55.5 1.1e-07
XP_011529308 (OMIM: 300276) PREDICTED: tumor necro ( 170)  250 55.5 1.3e-07
XP_011529306 (OMIM: 300276) PREDICTED: tumor necro ( 191)  250 55.6 1.4e-07
XP_016885195 (OMIM: 300276) PREDICTED: tumor necro ( 198)  250 55.6 1.4e-07
XP_016885193 (OMIM: 300276) PREDICTED: tumor necro ( 231)  250 55.6 1.6e-07
XP_011529304 (OMIM: 300276) PREDICTED: tumor necro ( 252)  250 55.7 1.7e-07
XP_011529303 (OMIM: 300276) PREDICTED: tumor necro ( 318)  250 55.8   2e-07
XP_011529302 (OMIM: 300276) PREDICTED: tumor necro ( 318)  250 55.8   2e-07
NP_001186616 (OMIM: 300276) tumor necrosis factor  ( 297)  249 55.6 2.1e-07
NP_068555 (OMIM: 300276) tumor necrosis factor rec ( 297)  249 55.6 2.1e-07
NP_001311135 (OMIM: 300276) tumor necrosis factor  ( 299)  249 55.6 2.1e-07
NP_001229239 (OMIM: 300276) tumor necrosis factor  ( 318)  249 55.6 2.2e-07
NP_689408 (OMIM: 611211) tumor necrosis factor rec ( 430)  226 51.5 5.1e-06
NP_116260 (OMIM: 611211) tumor necrosis factor rec ( 430)  226 51.5 5.1e-06
XP_011529305 (OMIM: 300276) PREDICTED: tumor necro ( 238)  213 48.9 1.7e-05


>>NP_071731 (OMIM: 129490,224900,604095,612630) tumor ne  (448 aa)
 initn: 3055 init1: 3055 opt: 3055  Z-score: 3009.0  bits: 566.0 E(85289): 7.3e-161
Smith-Waterman score: 3055; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)

               10        20        30        40        50        60
pF1KB0 MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 YMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 QGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 EAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 CLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 CLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRML
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIER
              370       380       390       400       410       420

              430       440        
pF1KB0 LDAVESLCADILEWAGVVPPASQPHAAS
       ::::::::::::::::::::::::::::
NP_071 LDAVESLCADILEWAGVVPPASQPHAAS
              430       440        

>>XP_011508805 (OMIM: 129490,224900,604095,612630) PREDI  (496 aa)
 initn: 3055 init1: 3055 opt: 3055  Z-score: 3008.4  bits: 566.0 E(85289): 7.9e-161
Smith-Waterman score: 3055; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:49-496)

                                             10        20        30
pF1KB0                               MAHVGDCTQTPWLPVLVVSLMCSARAEYSN
                                     ::::::::::::::::::::::::::::::
XP_011 GKVPSSPTAAVTQMRRKEAYRHPKVSPWERMAHVGDCTQTPWLPVLVVSLMCSARAEYSN
       20        30        40        50        60        70        

               40        50        60        70        80        90
pF1KB0 CGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRH
       80        90       100       110       120       130        

              100       110       120       130       140       150
pF1KB0 KDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVG
      140       150       160       170       180       190        

              160       170       180       190       200       210
pF1KB0 ATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYI
      200       210       220       230       240       250        

              220       230       240       250       260       270
pF1KB0 LKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSEN
      260       270       280       290       300       310        

              280       290       300       310       320       330
pF1KB0 DASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKIL
      320       330       340       350       360       370        

              340       350       360       370       380       390
pF1KB0 DVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGG
      380       390       400       410       420       430        

              400       410       420       430       440        
pF1KB0 MTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS
      440       450       460       470       480       490      

>>XP_006712267 (OMIM: 129490,224900,604095,612630) PREDI  (480 aa)
 initn: 1559 init1: 1559 opt: 1559  Z-score: 1538.5  bits: 294.0 E(85289): 5.9e-79
Smith-Waterman score: 2981; 93.3% identity (93.3% similar) in 480 aa overlap (1-448:1-480)

               10        20        30        40        50        60
pF1KB0 MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 YMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSG
              130       140       150       160       170       180

              190       200       210                              
pF1KB0 QGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAP----------------------
       ::::::::::::::::::::::::::::::::::::::                      
XP_006 QGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPGDGPHAPVPCFLDSPSTPPVGE
              190       200       210       220       230       240

                220       230       240       250       260        
pF1KB0 ----------ACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKS
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGCSLPPLSPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKS
              250       260       270       280       290       300

      270       280       290       300       310       320        
pF1KB0 ENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKK
              310       320       330       340       350       360

      330       340       350       360       370       380        
pF1KB0 ILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEI
              370       380       390       400       410       420

      390       400       410       420       430       440        
pF1KB0 GGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS
              430       440       450       460       470       480

>>XP_011508804 (OMIM: 129490,224900,604095,612630) PREDI  (528 aa)
 initn: 1559 init1: 1559 opt: 1559  Z-score: 1537.9  bits: 294.0 E(85289): 6.3e-79
Smith-Waterman score: 2981; 93.3% identity (93.3% similar) in 480 aa overlap (1-448:49-528)

                                             10        20        30
pF1KB0                               MAHVGDCTQTPWLPVLVVSLMCSARAEYSN
                                     ::::::::::::::::::::::::::::::
XP_011 GKVPSSPTAAVTQMRRKEAYRHPKVSPWERMAHVGDCTQTPWLPVLVVSLMCSARAEYSN
       20        30        40        50        60        70        

               40        50        60        70        80        90
pF1KB0 CGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRH
       80        90       100       110       120       130        

              100       110       120       130       140       150
pF1KB0 KDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVG
      140       150       160       170       180       190        

              160       170       180       190       200       210
pF1KB0 ATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYI
      200       210       220       230       240       250        

                                              220       230        
pF1KB0 LKTKPSAP--------------------------------ACCTSHPGKSVEAQVSKDEE
       ::::::::                                ::::::::::::::::::::
XP_011 LKTKPSAPGDGPHAPVPCFLDSPSTPPVGEPGCSLPPLSPACCTSHPGKSVEAQVSKDEE
      260       270       280       290       300       310        

      240       250       260       270       280       290        
pF1KB0 KKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSP
      320       330       340       350       360       370        

      300       310       320       330       340       350        
pF1KB0 ELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSR
      380       390       400       410       420       430        

      360       370       380       390       400       410        
pF1KB0 MLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQI
      440       450       460       470       480       490        

      420       430       440        
pF1KB0 ERLDAVESLCADILEWAGVVPPASQPHAAS
       ::::::::::::::::::::::::::::::
XP_011 ERLDAVESLCADILEWAGVVPPASQPHAAS
      500       510       520        

>>XP_016876141 (OMIM: 606122) PREDICTED: tumor necrosis   (328 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 266.0  bits: 58.0 E(85289): 4.4e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
XP_016 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
XP_016 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
XP_016 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
XP_016 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
XP_016 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       

>>XP_005266503 (OMIM: 606122) PREDICTED: tumor necrosis   (328 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 266.0  bits: 58.0 E(85289): 4.4e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
XP_005 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
XP_005 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
XP_005 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
XP_005 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
XP_005 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       

>>NP_001191387 (OMIM: 606122) tumor necrosis factor rece  (417 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 264.7  bits: 58.1 E(85289): 5.3e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
NP_001 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
NP_001 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
NP_001 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
NP_001 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
NP_001 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       

>>NP_683760 (OMIM: 606122) tumor necrosis factor recepto  (417 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 264.7  bits: 58.1 E(85289): 5.3e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
NP_683 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
NP_683 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
NP_683 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
NP_683 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
NP_683 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       

>>XP_005266502 (OMIM: 606122) PREDICTED: tumor necrosis   (423 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 264.6  bits: 58.1 E(85289): 5.3e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
XP_005 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
XP_005 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
XP_005 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
XP_005 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
XP_005 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       

>>XP_016876140 (OMIM: 606122) PREDICTED: tumor necrosis   (423 aa)
 initn: 201 init1: 103 opt: 262  Z-score: 264.6  bits: 58.1 E(85289): 5.3e-08
Smith-Waterman score: 267; 28.9% identity (55.5% similar) in 211 aa overlap (13-216:16-203)

                  10        20        30        40        50       
pF1KB0    MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPY
                      : ::.  : :..  : ..: ..:. ... : :  :  :::: :  
XP_016 MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELS
               10        20        30        40         50         

        60        70        80         90          100       110   
pF1KB0 LSCGYGTKDEDYGCVPCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAEC
         ::.:   ::  :: :  ..:..  :.: :.   ::   . : .:.     .  .:: :
XP_016 KECGFGY-GEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAIC
      60         70        80        90       100           110    

           120       130       140        150       160       170  
pF1KB0 GPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-ECVGATSGASANFPGTSGSSTLSPFQ
       : ::::.:  ...  ..  : :  :   ::  . .:.. .. ..       .:.. :: .
XP_016 GDCLPGFYR-KTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKI------ASTASSPRD
          120        130       140       150             160       

            180       190       200         210       220       230
pF1KB0 HAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMF--YILKTKPSAPACCTSHPGKSVE
        :         ::...  :..:. ..:. :. .:.    ... :::              
XP_016 TA---------LAAVICSALATV-LLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSE
                170       180        190       200       210       

              240       250       260       270       280       290
pF1KB0 AQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEP
                                                                   
XP_016 LSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASL
       220       230       240       250       260       270       




448 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:51:25 2016 done: Sat Nov  5 16:51:26 2016
 Total Scan time:  6.240 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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