Result of FASTA (omim) for pF1KB5284
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5284, 189 aa
  1>>>pF1KB5284 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7680+/-0.000383; mu= -2.3573+/- 0.024
 mean_var=211.5204+/-43.264, 0's: 0 Z-trim(119.5): 9  B-trim: 864 in 2/53
 Lambda= 0.088186
 statistics sampled from 33618 (33627) to 33618 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.394), width:  16
 Scan time:  6.520

The best scores are:                                      opt bits E(85289)
NP_981946 (OMIM: 151442) stathmin isoform a [Homo  ( 149)  623 90.9   1e-18
NP_981944 (OMIM: 151442) stathmin isoform a [Homo  ( 149)  623 90.9   1e-18
NP_005554 (OMIM: 151442) stathmin isoform a [Homo  ( 149)  623 90.9   1e-18
XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2  ( 174)  601 88.2   8e-18
NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Hom ( 179)  601 88.2 8.1e-18
NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [ ( 169)  562 83.2 2.4e-16
NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Hom ( 180)  562 83.2 2.5e-16
NP_001138926 (OMIM: 151442) stathmin isoform b [Ho ( 174)  542 80.7 1.4e-15
NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [ ( 187)  529 79.1 4.8e-15


>>NP_981946 (OMIM: 151442) stathmin isoform a [Homo sapi  (149 aa)
 initn: 711 init1: 623 opt: 623  Z-score: 457.1  bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)

        20        30        40        50        60        70       
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
                                     ::..: ::.: .:::.::.::.: : ..::
NP_981                            MASSDIQVKELEKRASGQAFELILSPRSKESVP
                                          10        20        30   

        80        90       100       110       120       130       
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
       ::  : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_981 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
            40        50        60        70        80        90   

       140       150       160       170       180             
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR    
        :::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :      
NP_981 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
           100       110       120       130       140         

>>NP_981944 (OMIM: 151442) stathmin isoform a [Homo sapi  (149 aa)
 initn: 711 init1: 623 opt: 623  Z-score: 457.1  bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)

        20        30        40        50        60        70       
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
                                     ::..: ::.: .:::.::.::.: : ..::
NP_981                            MASSDIQVKELEKRASGQAFELILSPRSKESVP
                                          10        20        30   

        80        90       100       110       120       130       
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
       ::  : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_981 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
            40        50        60        70        80        90   

       140       150       160       170       180             
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR    
        :::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :      
NP_981 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
           100       110       120       130       140         

>>NP_005554 (OMIM: 151442) stathmin isoform a [Homo sapi  (149 aa)
 initn: 711 init1: 623 opt: 623  Z-score: 457.1  bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)

        20        30        40        50        60        70       
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
                                     ::..: ::.: .:::.::.::.: : ..::
NP_005                            MASSDIQVKELEKRASGQAFELILSPRSKESVP
                                          10        20        30   

        80        90       100       110       120       130       
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
       ::  : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_005 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
            40        50        60        70        80        90   

       140       150       160       170       180             
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR    
        :::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :      
NP_005 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
           100       110       120       130       140         

>>XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2 isof  (174 aa)
 initn: 755 init1: 590 opt: 601  Z-score: 441.0  bits: 88.2 E(85289): 8e-18
Smith-Waterman score: 696; 63.8% identity (81.1% similar) in 185 aa overlap (5-188:2-173)

               10        20        30        40        50        60
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS
           ::::::::: ..::.::::  .: : . : :.            :::: ..:: .:
XP_005    MAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKRAS
                  10        20        30                    40     

               70         80        90       100       110         
pF1KB5 GQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEK
       ::.::.:::::: .. .:.  :: :...: ::::::::::::::::: :::..::.::::
XP_005 GQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEK
          50        60         70        80        90       100    

     120       130       140       150       160       170         
pF1KB5 REHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRK
       :::::::.:::.:::::: :::.:::  :::. ::::::.:::..::::::..:: :::.
XP_005 REHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRR
          110       120       130       140       150       160    

     180         
pF1KB5 NKELKEEASR
       ::::. : : 
XP_005 NKELQVELSG
          170    

>>NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Homo sa  (179 aa)
 initn: 755 init1: 590 opt: 601  Z-score: 440.8  bits: 88.2 E(85289): 8.1e-18
Smith-Waterman score: 698; 63.3% identity (80.3% similar) in 188 aa overlap (2-188:4-178)

                 10        20        30        40        50        
pF1KB5   MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
          :  ::::::::: ..::.::::  .: : . : :.            :::: ..:: 
NP_008 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR
               10        20        30                    40        

       60        70         80        90       100       110       
pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA
       .:::.::.:::::: .. .:.  :: :...: ::::::::::::::::: :::..::.::
NP_008 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA
       50        60        70         80        90       100       

       120       130       140       150       160       170       
pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV
       :::::::::.:::.:::::: :::.:::  :::. ::::::.:::..::::::..:: ::
NP_008 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEV
       110       120       130       140       150       160       

       180         
pF1KB5 RKNKELKEEASR
       :.::::. : : 
NP_008 RRNKELQVELSG
       170         

>>NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [Homo  (169 aa)
 initn: 661 init1: 438 opt: 562  Z-score: 414.4  bits: 83.2 E(85289): 2.4e-16
Smith-Waterman score: 624; 59.1% identity (78.5% similar) in 181 aa overlap (10-188:1-168)

               10        20        30        40        50        60
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS
                :::: ..::.:::: ..:  .. :.:            .:::: .:.: .:
NP_001          MKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKRAS
                        10        20                    30         

               70          80        90       100       110        
pF1KB5 GQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAE
       ::::::::: :: :  ::  . .: :...: ::::.::.::::::::: :::..::.:::
NP_001 GQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAE
      40        50         60        70        80        90        

      120       130       140       150       160       170        
pF1KB5 KREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVR
       .:::::::..::.:::::: ..:.:::  ::: .:: :::::::. :::.::. :: :::
NP_001 RREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVR
      100       110       120       130       140       150        

      180         
pF1KB5 KNKELKEEASR
       .::: .:: : 
NP_001 RNKEQREEMSG
      160         

>>NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Homo sa  (180 aa)
 initn: 700 init1: 438 opt: 562  Z-score: 414.0  bits: 83.2 E(85289): 2.5e-16
Smith-Waterman score: 663; 59.8% identity (79.4% similar) in 189 aa overlap (2-188:4-179)

                 10        20        30        40        50        
pF1KB5   MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
          :..::::::::: ..::.:::: ..:  .. :.:            .:::: .:.: 
NP_056 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKR
               10        20        30                    40        

       60        70          80        90       100       110      
pF1KB5 TSGQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHL
       .:::::::::: :: :  ::  . .: :...: ::::.::.::::::::: :::..::.:
NP_056 ASGQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQL
       50        60         70        80        90       100       

        120       130       140       150       160       170      
pF1KB5 AEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEE
       ::.:::::::..::.:::::: ..:.:::  ::: .:: :::::::. :::.::. :: :
NP_056 AERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAE
       110       120       130       140       150       160       

        180         
pF1KB5 VRKNKELKEEASR
       ::.::: .:: : 
NP_056 VRRNKEQREEMSG
       170       180

>>NP_001138926 (OMIM: 151442) stathmin isoform b [Homo s  (174 aa)
 initn: 542 init1: 542 opt: 542  Z-score: 400.4  bits: 80.7 E(85289): 1.4e-15
Smith-Waterman score: 542; 71.5% identity (91.1% similar) in 123 aa overlap (48-170:4-126)

        20        30        40        50        60        70       
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
                                     ::..: ::.: .:::.::.::.: : ..::
NP_001                            MASSDIQVKELEKRASGQAFELILSPRSKESVP
                                          10        20        30   

        80        90       100       110       120       130       
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
       ::  : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_001 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
            40        50        60        70        80        90   

       140       150       160       170       180                 
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR        
        :::.:::..:::.:::::::..:: ::::.::                           
NP_001 SKMAEEKLTHKMEANKENREAQMAAKLERLREKMYFWTHGPGAHPAQISAEQSCLHSVPA
           100       110       120       130       140       150   

NP_001 LCPALGLQSALITWSDLSHHH
           160       170    

>>NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [Homo  (187 aa)
 initn: 625 init1: 518 opt: 529  Z-score: 391.1  bits: 79.1 E(85289): 4.8e-15
Smith-Waterman score: 626; 63.5% identity (80.0% similar) in 170 aa overlap (2-170:4-160)

                 10        20        30        40        50        
pF1KB5   MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
          :  ::::::::: ..::.::::  .: : . : :.            :::: ..:: 
NP_001 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR
               10        20        30                    40        

       60        70         80        90       100       110       
pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA
       .:::.::.:::::: .. .:.  :: :...: ::::::::::::::::: :::..::.::
NP_001 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA
       50        60        70         80        90       100       

       120       130       140       150       160       170       
pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV
       :::::::::.:::.:::::: :::.:::  :::. ::::::.:::..::::::       
NP_001 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKLVKFISS
       110       120       130       140       150       160       

       180                 
pF1KB5 RKNKELKEEASR        
                           
NP_001 ELKESIESQFLELQREGEKQ
       170       180       




189 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:24:08 2016 done: Sat Nov  5 12:24:09 2016
 Total Scan time:  6.520 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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