Result of FASTA (omim) for
pF1KB4568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4568, 370 aa
1>>>pF1KB4568 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3902+/-0.000344; mu= 16.8011+/- 0.022
mean_var=74.3484+/-14.571, 0's: 0 Z-trim(115.3): 27 B-trim: 0 in 0/51
Lambda= 0.148744
statistics sampled from 25567 (25594) to 25567 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.3), width: 16
Scan time: 8.510
The best scores are: opt bits E(85289)
NP_064536 (OMIM: 616712) stAR-related lipid transf ( 370) 2497 545.0 1e-154
XP_011509801 (OMIM: 616712) PREDICTED: stAR-relate ( 269) 1830 401.8 9.5e-112
NP_067036 (OMIM: 606055) phosphatidylcholine trans ( 214) 377 89.9 5.7e-18
NP_001317306 (OMIM: 606055) phosphatidylcholine tr ( 203) 346 83.3 5.5e-16
NP_001317307 (OMIM: 606055) phosphatidylcholine tr ( 219) 339 81.8 1.7e-15
NP_001095872 (OMIM: 606055) phosphatidylcholine tr ( 142) 292 71.6 1.3e-12
XP_016880402 (OMIM: 606055) PREDICTED: phosphatidy ( 131) 261 64.9 1.2e-10
>>NP_064536 (OMIM: 616712) stAR-related lipid transfer p (370 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2898.8 bits: 545.0 E(85289): 1e-154
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KB4 MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 YCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEG
310 320 330 340 350 360
370
pF1KB4 SCGPARIEYA
::::::::::
NP_064 SCGPARIEYA
370
>>XP_011509801 (OMIM: 616712) PREDICTED: stAR-related li (269 aa)
initn: 1830 init1: 1830 opt: 1830 Z-score: 2127.3 bits: 401.8 E(85289): 9.5e-112
Smith-Waterman score: 1830; 100.0% identity (100.0% similar) in 269 aa overlap (102-370:1-269)
80 90 100 110 120 130
pF1KB4 ASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHHPPEPKAQTEGN
::::::::::::::::::::::::::::::
XP_011 MKRLEEMSNMFQSSGVQHHPPEPKAQTEGN
10 20 30
140 150 160 170 180 190
pF1KB4 EDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKK
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB4 WDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB4 HPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGM
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB4 PDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA
220 230 240 250 260
>>NP_067036 (OMIM: 606055) phosphatidylcholine transfer (214 aa)
initn: 328 init1: 131 opt: 377 Z-score: 443.6 bits: 89.9 E(85289): 5.7e-18
Smith-Waterman score: 377; 30.6% identity (68.9% similar) in 183 aa overlap (141-321:30-206)
120 130 140 150 160 170
pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT
:..... . ....: : ::.:.:::.
NP_067 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV
10 20 30 40 50
180 190 200 210 220 230
pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY
: .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .:::::
NP_067 LEDCSPTLLADIYMDSDYRKQWDQYV--KELYEQEC-NGETVVYWEVKYPFPMSNRDYVY
60 70 80 90 100 110
240 250 260 270 280
pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL
.: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: ..
NP_067 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK
: ::: .: . ..: ...:.:.::. . :
NP_067 YYFDNPGGQIPSWLINWAAKNGVPNFLKDMARACQNYLKKT
180 190 200 210
350 360 370
pF1KB4 ATSQSSERKNEGSCGPARIEYA
>>NP_001317306 (OMIM: 606055) phosphatidylcholine transf (203 aa)
initn: 278 init1: 134 opt: 346 Z-score: 408.0 bits: 83.3 E(85289): 5.5e-16
Smith-Waterman score: 346; 30.2% identity (68.6% similar) in 172 aa overlap (141-310:30-195)
120 130 140 150 160 170
pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT
:..... . ....: : ::.:.:::.
NP_001 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV
10 20 30 40 50
180 190 200 210 220 230
pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY
: .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .:::::
NP_001 LEDCSPTLLADIYMDSDYRKQWDQYVK--ELYEQEC-NGETVVYWEVKYPFPMSNRDYVY
60 70 80 90 100 110
240 250 260 270 280
pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL
.: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: ..
NP_001 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK
: ::: .: . ..: ...:
NP_001 YYFDNPGGQIPSWLINWAAKGGNCSGSLYH
180 190 200
>>NP_001317307 (OMIM: 606055) phosphatidylcholine transf (219 aa)
initn: 275 init1: 131 opt: 339 Z-score: 399.4 bits: 81.8 E(85289): 1.7e-15
Smith-Waterman score: 339; 30.5% identity (68.3% similar) in 167 aa overlap (141-305:30-190)
120 130 140 150 160 170
pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT
:..... . ....: : ::.:.:::.
NP_001 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV
10 20 30 40 50
180 190 200 210 220 230
pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY
: .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .:::::
NP_001 LEDCSPTLLADIYMDSDYRKQWDQYV--KELYEQEC-NGETVVYWEVKYPFPMSNRDYVY
60 70 80 90 100 110
240 250 260 270 280
pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL
.: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: ..
NP_001 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK
: ::: .: . ..:
NP_001 YYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFLANPNILQ
180 190 200 210
>>NP_001095872 (OMIM: 606055) phosphatidylcholine transf (142 aa)
initn: 229 init1: 85 opt: 292 Z-score: 347.6 bits: 71.6 E(85289): 1.3e-12
Smith-Waterman score: 292; 32.1% identity (70.0% similar) in 140 aa overlap (184-321:1-134)
160 170 180 190 200 210
pF1KB4 RRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVL
.:..:::.:: : :. :.. .: :.
NP_001 MDSDYRKQWDQYVK--ELYEQEC-NGETVV
10 20
220 230 240 250 260 270
pF1KB4 HWVTHFPYPMYSRDYVYVR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQM
.: ...:.:: .:::::.: : ..:.:. .. :...:.. :.. : .::..:....
NP_001 YWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSL
30 40 50 60 70 80
280 290 300 310 320 330
pF1KB4 VIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIK
.: .: ..: .. : ::: .: . ..: ...:.:.::. . :
NP_001 AI---ESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMARACQNYLKKT
90 100 110 120 130 140
340 350 360 370
pF1KB4 VKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA
>>XP_016880402 (OMIM: 606055) PREDICTED: phosphatidylcho (131 aa)
initn: 176 init1: 73 opt: 261 Z-score: 312.1 bits: 64.9 E(85289): 1.2e-10
Smith-Waterman score: 261; 31.8% identity (69.8% similar) in 129 aa overlap (184-310:1-123)
160 170 180 190 200 210
pF1KB4 RRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVL
.:..:::.:: : :. :.. .: :.
XP_016 MDSDYRKQWDQYV--KELYEQEC-NGETVV
10 20
220 230 240 250 260 270
pF1KB4 HWVTHFPYPMYSRDYVYVR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQM
.: ...:.:: .:::::.: : ..:.:. .. :...:.. :.. : .::..:....
XP_016 YWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSL
30 40 50 60 70 80
280 290 300 310 320 330
pF1KB4 VIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIK
.: .: ..: .. : ::: .: . ..: ...:
XP_016 AI---ESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKGGNCSGSLYH
90 100 110 120 130
340 350 360 370
pF1KB4 VKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA
370 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:19:55 2016 done: Sat Nov 5 12:19:56 2016
Total Scan time: 8.510 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]