Result of FASTA (omim) for pF1KB6618
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6618, 433 aa
  1>>>pF1KB6618 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5828+/-0.000372; mu= 16.1691+/- 0.023
 mean_var=80.5926+/-15.524, 0's: 0 Z-trim(114.0): 188  B-trim: 18 in 1/54
 Lambda= 0.142865
 statistics sampled from 23430 (23644) to 23430 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.277), width:  16
 Scan time:  8.070

The best scores are:                                      opt bits E(85289)
NP_002794 (OMIM: 154365) 26S protease regulatory s ( 433) 2856 598.5 1.1e-170
NP_001186092 (OMIM: 601681) 26S protease regulator ( 398) 1168 250.6 5.4e-66
NP_002796 (OMIM: 601681) 26S protease regulatory s ( 406) 1168 250.6 5.5e-66
NP_002797 (OMIM: 602708) 26S protease regulatory s ( 403) 1077 231.8 2.4e-60
NP_001317141 (OMIM: 602706) 26S protease regulator ( 367) 1050 226.3 1.1e-58
XP_016876959 (OMIM: 602706) PREDICTED: 26S proteas ( 367) 1050 226.3 1.1e-58
NP_002793 (OMIM: 602706) 26S protease regulatory s ( 440) 1050 226.3 1.2e-58
XP_016876961 (OMIM: 602708) PREDICTED: 26S proteas ( 288) 1020 220.0 6.3e-57
NP_002795 (OMIM: 186852) 26S protease regulatory s ( 439)  982 212.3   2e-54
NP_694546 (OMIM: 602707) 26S protease regulatory s ( 387)  973 210.4 6.6e-54
NP_006494 (OMIM: 602707) 26S protease regulatory s ( 418)  960 207.7 4.5e-53
XP_016873515 (OMIM: 186852) PREDICTED: 26S proteas ( 461)  934 202.4   2e-51
XP_005250562 (OMIM: 154365) PREDICTED: 26S proteas ( 141)  916 198.4   1e-50
NP_001191382 (OMIM: 154365) 26S protease regulator ( 141)  916 198.4   1e-50
XP_011523903 (OMIM: 604581,610246,614487) PREDICTE ( 730)  706 155.5   4e-37
NP_006787 (OMIM: 604581,610246,614487) AFG3-like p ( 797)  706 155.6 4.3e-37
NP_009057 (OMIM: 167320,601023,613954,616687) tran ( 806)  703 155.0 6.7e-37
XP_011515297 (OMIM: 611941) PREDICTED: ATPase fami ( 953)  647 143.5 2.3e-33
XP_011515296 (OMIM: 611941) PREDICTED: ATPase fami (1260)  647 143.5 2.9e-33
NP_054828 (OMIM: 611941) ATPase family AAA domain- (1390)  647 143.6 3.1e-33
XP_011531234 (OMIM: 615347) PREDICTED: ATPase fami ( 791)  636 141.1 9.5e-33
XP_011531233 (OMIM: 615347) PREDICTED: ATPase fami ( 837)  636 141.2 9.9e-33
XP_011531232 (OMIM: 615347) PREDICTED: ATPase fami ( 841)  636 141.2   1e-32
XP_011531231 (OMIM: 615347) PREDICTED: ATPase fami ( 843)  636 141.2   1e-32
XP_011531230 (OMIM: 615347) PREDICTED: ATPase fami ( 849)  636 141.2   1e-32
XP_006712094 (OMIM: 615347) PREDICTED: ATPase fami (1067)  636 141.2 1.2e-32
XP_011531227 (OMIM: 615347) PREDICTED: ATPase fami (1079)  636 141.2 1.2e-32
XP_011531226 (OMIM: 615347) PREDICTED: ATPase fami (1083)  636 141.2 1.2e-32
NP_001229267 (OMIM: 615347) ATPase family AAA doma (1453)  636 141.3 1.5e-32
NP_060022 (OMIM: 615347) ATPase family AAA domain- (1458)  636 141.3 1.5e-32
XP_006712093 (OMIM: 615347) PREDICTED: ATPase fami (1460)  636 141.3 1.5e-32
XP_011531223 (OMIM: 615347) PREDICTED: ATPase fami (1467)  636 141.3 1.6e-32
XP_005264429 (OMIM: 615347) PREDICTED: ATPase fami (1472)  636 141.3 1.6e-32
XP_016859864 (OMIM: 615347) PREDICTED: ATPase fami (1492)  636 141.3 1.6e-32
XP_011531222 (OMIM: 615347) PREDICTED: ATPase fami (1497)  636 141.3 1.6e-32
XP_011531221 (OMIM: 615347) PREDICTED: ATPase fami (1506)  636 141.3 1.6e-32
XP_011531220 (OMIM: 615347) PREDICTED: ATPase fami (1511)  636 141.3 1.6e-32
NP_003110 (OMIM: 602783,607259) paraplegin isoform ( 795)  622 138.3   7e-32
XP_006721327 (OMIM: 602783,607259) PREDICTED: para ( 809)  622 138.3 7.1e-32
XP_016879086 (OMIM: 602783,607259) PREDICTED: para ( 618)  618 137.4   1e-31
XP_016879087 (OMIM: 602783,607259) PREDICTED: para ( 561)  613 136.3 1.9e-31
NP_001240795 (OMIM: 607472) ATP-dependent zinc met ( 683)  588 131.2   8e-30
NP_055078 (OMIM: 607472) ATP-dependent zinc metall ( 716)  588 131.2 8.3e-30
XP_011517602 (OMIM: 607472) PREDICTED: ATP-depende ( 740)  588 131.2 8.5e-30
NP_647473 (OMIM: 607472) ATP-dependent zinc metall ( 773)  588 131.2 8.9e-30
NP_001304728 (OMIM: 613940,616577) spermatogenesis ( 695)  554 124.2   1e-27
XP_011529981 (OMIM: 613940,616577) PREDICTED: sper ( 790)  554 124.2 1.2e-27
XP_016863317 (OMIM: 613940,616577) PREDICTED: sper ( 819)  554 124.3 1.2e-27
NP_001332785 (OMIM: 613940,616577) spermatogenesis ( 892)  554 124.3 1.3e-27
NP_660208 (OMIM: 613940,616577) spermatogenesis-as ( 893)  554 124.3 1.3e-27


>>NP_002794 (OMIM: 154365) 26S protease regulatory subun  (433 aa)
 initn: 2856 init1: 2856 opt: 2856  Z-score: 3185.6  bits: 598.5 E(85289): 1.1e-170
Smith-Waterman score: 2856; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)

               10        20        30        40        50        60
pF1KB6 MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 IGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHAR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY
              370       380       390       400       410       420

              430   
pF1KB6 AKFSATPRYMTYN
       :::::::::::::
NP_002 AKFSATPRYMTYN
              430   

>>NP_001186092 (OMIM: 601681) 26S protease regulatory su  (398 aa)
 initn: 1149 init1: 1149 opt: 1168  Z-score: 1305.8  bits: 250.6 E(85289): 5.4e-66
Smith-Waterman score: 1168; 50.8% identity (73.9% similar) in 372 aa overlap (53-418:14-384)

             30        40        50        60           70         
pF1KB6 RALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGI---KESDTGLAPPALWD
                                     :  :.::.::  :   : ..         .
NP_001                  MELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNE
                                10        20        30        40   

      80        90          100       110       120       130      
pF1KB6 LAADKQTLQSEQPL---QVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEE
       : :  . :. :  :   : .   ... :  .  : ...:.  .:::::.. ..  .:.  
NP_001 LNAKVRLLREELQLLQEQGSYVGEVVRA-MDKKKVLVKVHPEGKFVVDVDKNIDINDVTP
            50        60        70         80        90       100  

        140       150       160       170       180       190      
pF1KB6 GMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLL
       . ::..  ..: .:  :: :.:: :..:.::. :: ::  .::  .::....::.: :. 
NP_001 NCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK
            110       120       130       140       150       160  

        200       210       220       230       240       250      
pF1KB6 HPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARM
       ::: :  :::  ::::::.::::::::: :::::..::  :::: :::::::..::::::
NP_001 HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARM
            170       180       190       200       210       220  

        260       270       280       290       300       310      
pF1KB6 VRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIK
       ::::: ::: .   .::.::::.::..:.. :.:::.:::::::::.::::::.   :::
NP_001 VRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK
            230       240       250       260       270       280  

        320       330       340       350       360       370      
pF1KB6 VLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARL
       :.::::: : :: ::.::::.::::::  :. :.:  :.:::.:.:.. : : .. .:.:
NP_001 VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEL
            290       300       310       320       330       340  

        380       390       400       410       420       430   
pF1KB6 CPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
        :...:::...:::::::.:.: ::  .:..::  :: ::..               
NP_001 MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 
            350       360       370       380       390         

>>NP_002796 (OMIM: 601681) 26S protease regulatory subun  (406 aa)
 initn: 1149 init1: 1149 opt: 1168  Z-score: 1305.7  bits: 250.6 E(85289): 5.5e-66
Smith-Waterman score: 1168; 50.8% identity (73.9% similar) in 372 aa overlap (53-418:22-392)

             30        40        50        60           70         
pF1KB6 RALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGI---KESDTGLAPPALWD
                                     :  :.::.::  :   : ..         .
NP_002          MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNE
                        10        20        30        40        50 

      80        90          100       110       120       130      
pF1KB6 LAADKQTLQSEQPL---QVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEE
       : :  . :. :  :   : .   ... :  .  : ...:.  .:::::.. ..  .:.  
NP_002 LNAKVRLLREELQLLQEQGSYVGEVVRA-MDKKKVLVKVHPEGKFVVDVDKNIDINDVTP
              60        70         80        90       100       110

        140       150       160       170       180       190      
pF1KB6 GMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLL
       . ::..  ..: .:  :: :.:: :..:.::. :: ::  .::  .::....::.: :. 
NP_002 NCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK
              120       130       140       150       160       170

        200       210       220       230       240       250      
pF1KB6 HPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARM
       ::: :  :::  ::::::.::::::::: :::::..::  :::: :::::::..::::::
NP_002 HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARM
              180       190       200       210       220       230

        260       270       280       290       300       310      
pF1KB6 VRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIK
       ::::: ::: .   .::.::::.::..:.. :.:::.:::::::::.::::::.   :::
NP_002 VRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK
              240       250       260       270       280       290

        320       330       340       350       360       370      
pF1KB6 VLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARL
       :.::::: : :: ::.::::.::::::  :. :.:  :.:::.:.:.. : : .. .:.:
NP_002 VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEL
              300       310       320       330       340       350

        380       390       400       410       420       430   
pF1KB6 CPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
        :...:::...:::::::.:.: ::  .:..::  :: ::..               
NP_002 MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 
              360       370       380       390       400       

>>NP_002797 (OMIM: 602708) 26S protease regulatory subun  (403 aa)
 initn: 1104 init1: 1052 opt: 1077  Z-score: 1204.4  bits: 231.8 E(85289): 2.4e-60
Smith-Waterman score: 1078; 45.5% identity (75.1% similar) in 374 aa overlap (46-419:34-391)

          20        30        40        50        60        70     
pF1KB6 EKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPP
                                     :...  ...: ....:::   :.. .    
NP_002 PGIPYERRLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSEN----
            10        20        30        40        50             

          80        90       100       110       120       130     
pF1KB6 ALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIE
          :: :    :::    :..   ....  .:. :.:... .  ..::    :.  . ..
NP_002 ---DLKA----LQSVG--QIV--GEVLKQLTEE-KFIVKATNGPRYVVGCRRQLDKSKLK
         60              70          80         90       100       

         140       150       160       170       180       190     
pF1KB6 EGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPL
        : ::..: .   :   :: ..:: :  :. :.  .:.::..:: .:::..::::.: ::
NP_002 PGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPL
       110       120       130       140       150       160       

         200       210       220       230       240       250     
pF1KB6 LHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGAR
        .:: :  .:: :::: ::.::::::::: :::::.. :  :..:..: .:.::.::.::
NP_002 TNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESAR
       170       180       190       200       210       220       

         260       270       280       290       300       310     
pF1KB6 MVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNI
       ..::.:..:: .. :.::.:::::::: ::..:...: :.:::..::.::.::::    .
NP_002 LIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRV
       230       240       250       260       270       280       

         320       330       340       350       360       370     
pF1KB6 KVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLAR
       :..:::::::::::::.:::::::::...::. ..:  :.::::  .. . .: .: ...
NP_002 KMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVK
       290       300       310       320       330       340       

         380       390       400       410       420       430   
pF1KB6 LCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
       :  . .::..:.:::::::::::: . .....::..:: ::  :              
NP_002 LSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV  
       350       360       370       380       390       400     

>>NP_001317141 (OMIM: 602706) 26S protease regulatory su  (367 aa)
 initn: 1022 init1: 1022 opt: 1050  Z-score: 1174.9  bits: 226.3 E(85289): 1.1e-58
Smith-Waterman score: 1050; 47.3% identity (76.2% similar) in 336 aa overlap (92-427:33-362)

              70        80        90       100       110       120 
pF1KB6 LTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKF
                                     :..:.   .::    .: . :....  .. 
NP_001 EEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEII----DDNHAIVSTSVGSEH
             10        20        30        40            50        

             130       140       150       160       170       180 
pF1KB6 VVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCK
        :.. . :    .: :  : .... . .   :    :: ::.:.::. :. ::.:.::  
NP_001 YVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLD
       60        70        80        90       100       110        

             190       200       210       220       230       240 
pF1KB6 EQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI
       .::....: :: :: ::: . ..::.:::::.:.::::::::: :.::::.:.: :.::.
NP_001 NQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV
      120       130       140       150       160       170        

             250       260       270       280       290       300 
pF1KB6 GSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLE
       ::::.:::.:.: ..:::::..:. .   ..:.:::::::  :.:...::. :.::::::
NP_001 GSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLE
      180       190       200       210       220       230        

             310       320       330       340       350       360 
pF1KB6 LINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARS
       :.::::::: ::..::.::::: .::::::.::::.:::::: ::: . . .::.::.  
NP_001 LLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSR
      240       250       260       270       280       290        

             370       380       390       400       410       420 
pF1KB6 MSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYA
       :..  :. .. :     . .::.:...:::::..:.: ::  .:..:: .. ..:.  : 
NP_001 MTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVL--YK
      300       310       320       330       340       350        

             430   
pF1KB6 KFSATPRYMTYN
       :  .::      
NP_001 KQEGTPEGLYL 
        360        

>>XP_016876959 (OMIM: 602706) PREDICTED: 26S protease re  (367 aa)
 initn: 1022 init1: 1022 opt: 1050  Z-score: 1174.9  bits: 226.3 E(85289): 1.1e-58
Smith-Waterman score: 1050; 47.3% identity (76.2% similar) in 336 aa overlap (92-427:33-362)

              70        80        90       100       110       120 
pF1KB6 LTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKF
                                     :..:.   .::    .: . :....  .. 
XP_016 EEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEII----DDNHAIVSTSVGSEH
             10        20        30        40            50        

             130       140       150       160       170       180 
pF1KB6 VVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCK
        :.. . :    .: :  : .... . .   :    :: ::.:.::. :. ::.:.::  
XP_016 YVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLD
       60        70        80        90       100       110        

             190       200       210       220       230       240 
pF1KB6 EQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI
       .::....: :: :: ::: . ..::.:::::.:.::::::::: :.::::.:.: :.::.
XP_016 NQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV
      120       130       140       150       160       170        

             250       260       270       280       290       300 
pF1KB6 GSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLE
       ::::.:::.:.: ..:::::..:. .   ..:.:::::::  :.:...::. :.::::::
XP_016 GSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLE
      180       190       200       210       220       230        

             310       320       330       340       350       360 
pF1KB6 LINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARS
       :.::::::: ::..::.::::: .::::::.::::.:::::: ::: . . .::.::.  
XP_016 LLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSR
      240       250       260       270       280       290        

             370       380       390       400       410       420 
pF1KB6 MSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYA
       :..  :. .. :     . .::.:...:::::..:.: ::  .:..:: .. ..:.  : 
XP_016 MTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVL--YK
      300       310       320       330       340       350        

             430   
pF1KB6 KFSATPRYMTYN
       :  .::      
XP_016 KQEGTPEGLYL 
        360        

>>NP_002793 (OMIM: 602706) 26S protease regulatory subun  (440 aa)
 initn: 1022 init1: 1022 opt: 1050  Z-score: 1173.8  bits: 226.3 E(85289): 1.2e-58
Smith-Waterman score: 1050; 47.3% identity (76.2% similar) in 336 aa overlap (92-427:106-435)

              70        80        90       100       110       120 
pF1KB6 LTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKF
                                     :..:.   .::    .: . :....  .. 
NP_002 EEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEII----DDNHAIVSTSVGSEH
          80        90       100       110           120       130 

             130       140       150       160       170       180 
pF1KB6 VVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCK
        :.. . :    .: :  : .... . .   :    :: ::.:.::. :. ::.:.::  
NP_002 YVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLD
             140       150       160       170       180       190 

             190       200       210       220       230       240 
pF1KB6 EQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI
       .::....: :: :: ::: . ..::.:::::.:.::::::::: :.::::.:.: :.::.
NP_002 NQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV
             200       210       220       230       240       250 

             250       260       270       280       290       300 
pF1KB6 GSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLE
       ::::.:::.:.: ..:::::..:. .   ..:.:::::::  :.:...::. :.::::::
NP_002 GSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLE
             260       270       280       290       300       310 

             310       320       330       340       350       360 
pF1KB6 LINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARS
       :.::::::: ::..::.::::: .::::::.::::.:::::: ::: . . .::.::.  
NP_002 LLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSR
             320       330       340       350       360       370 

             370       380       390       400       410       420 
pF1KB6 MSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYA
       :..  :. .. :     . .::.:...:::::..:.: ::  .:..:: .. ..:.  : 
NP_002 MTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVL--YK
             380       390       400       410       420           

             430   
pF1KB6 KFSATPRYMTYN
       :  .::      
NP_002 KQEGTPEGLYL 
     430       440 

>>XP_016876961 (OMIM: 602708) PREDICTED: 26S protease re  (288 aa)
 initn: 1068 init1: 1020 opt: 1020  Z-score: 1143.0  bits: 220.0 E(85289): 6.3e-57
Smith-Waterman score: 1020; 54.7% identity (83.1% similar) in 267 aa overlap (153-419:10-276)

            130       140       150       160       170       180  
pF1KB6 VDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKE
                                     :: ..:: :  :. :.  .:.::..:: .:
XP_016                      MTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSE
                                    10        20        30         

            190       200       210       220       230       240  
pF1KB6 QIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIG
       ::..::::.: :: .:: :  .:: :::: ::.::::::::: :::::.. :  :..:..
XP_016 QIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVS
      40        50        60        70        80        90         

            250       260       270       280       290       300  
pF1KB6 SELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLEL
       : .:.::.::.::..::.:..:: .. :.::.:::::::: ::..:...: :.:::..::
XP_016 SSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMEL
     100       110       120       130       140       150         

            310       320       330       340       350       360  
pF1KB6 INQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSM
       .::.::::    .:..:::::::::::::.:::::::::...::. ..:  :.::::  .
XP_016 LNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPI
     160       170       180       190       200       210         

            370       380       390       400       410       420  
pF1KB6 SVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAK
       . . .: .: ...:  . .::..:.:::::::::::: . .....::..:: ::  :   
XP_016 TKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKL
     220       230       240       250       260       270         

            430   
pF1KB6 FSATPRYMTYN
                  
XP_016 ESKLDYKPV  
     280          

>>NP_002795 (OMIM: 186852) 26S protease regulatory subun  (439 aa)
 initn: 981 init1: 958 opt: 982  Z-score: 1098.0  bits: 212.3 E(85289): 2e-54
Smith-Waterman score: 984; 40.4% identity (66.6% similar) in 416 aa overlap (3-416:27-427)

                                       10        20        30      
pF1KB6                         MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTY
                                 : .: .  : . .:  ..  : :: ..: ..:. 
NP_002 MNLLPNIESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRT-RLLD-SEIKIMKS-
               10        20        30        40          50        

         40        50        60        70        80        90      
pF1KB6 GQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVA
              .. .:  ..: .  ::.:     .:.   .  .:  :...   : . .: .  
NP_002 -------EVLRVTHELQAMKDKIKE-----NSEKIKVNKTLPYLVSNVIELLDVDPNDQE
               60        70             80        90       100     

        100       110       120         130       140       150    
pF1KB6 RCTKIINADSEDPKYIINVKQFAK--FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLP
       .    :. ::.       .:  ..  . . .   :    .. :  :::....: :   ::
NP_002 EDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLP
         110       120       130       140       150       160     

          160       170       180       190       200       210    
pF1KB6 PKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLL
        . :  :  :.:.:.:   :::.::  .::..: :..  :. : :.: ::::.::::::.
NP_002 TEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLM
         170       180       190       200       210       220     

          220       230       240       250       260       270    
pF1KB6 FGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFF
       .::::::::: ::: : .: : :... : .::: ..:.::..::. : .:. :   .::.
NP_002 YGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFI
         230       240       250       260       270       280     

          280       290       300       310       320       330    
pF1KB6 DEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRP
       ::.::::  :::.  .:: :::::::::.::::::.:  ..::. :::: : :::::.: 
NP_002 DELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRS
         290       300       310       320       330       340     

          340       350       360       370       380       390    
pF1KB6 GRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGM
       ::::::::: .:. :.:..:..::.:.:.:  :. .: :::   . .::. ..::.::::
NP_002 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGM
         350       360       370       380       390       400     

          400       410       420       430   
pF1KB6 FAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
       .:.:      :..:..:.. .:                 
NP_002 IALRRGATELTHEDYMEGILEVQAKKKANLQYYA     
         410       420       430              

>>NP_694546 (OMIM: 602707) 26S protease regulatory subun  (387 aa)
 initn: 955 init1: 955 opt: 973  Z-score: 1088.8  bits: 210.4 E(85289): 6.6e-54
Smith-Waterman score: 973; 42.5% identity (69.9% similar) in 379 aa overlap (45-418:8-377)

           20        30        40        50        60        70    
pF1KB6 DEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAP
                                     .....:.:  :  .  . ::.  :  :  :
NP_694                        MEEIGILVEKAQDEIPALSVSRPQ-TGL--SFLGPEP
                                      10        20           30    

           80         90         100       110       120       130 
pF1KB6 PALWDLAAD-KQTLQSEQ--PLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAP
         : :: .  :. ..  :  :: ...  . .. ..     :..    ... : . . .  
NP_694 EDLEDLYSRYKEEVKRIQSIPLVIGQFLEAVDQNTA----IVGSTTGSNYYVRILSTIDR
           40        50        60        70            80        90

             140       150       160       170       180       190 
pF1KB6 TDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVV
         .. .  :.. ...  .   :::. : .. :.  ..:::: :.:.::   : ...::.:
NP_694 ELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAV
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KB6 ETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVG
       : :: : : . ..::.::.:::..:::: :::. :.:::..: : ::::.:::.::::.:
NP_694 ELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLG
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KB6 EGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDP
       :: ::::..:..:. .   .::.::::::.  :::  .:.: :::: .:::.::.:::: 
NP_694 EGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQ
              220       230       240       250       260       270

             320       330       340       350       360       370 
pF1KB6 RGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFE
         :.::.::::: :::::::.::::::::::: ::: . .  ::.  . .:.. ... .:
NP_694 NVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLE
              280       290       300       310       320       330

              380        390       400       410       420         
pF1KB6 -LLARLCPNS-TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRY
         .::  :.. .::.: :.: :.::.:.:  : :.  ::: .: . :::           
NP_694 DYVAR--PDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 
                340       350       360       370       380        

     430   
pF1KB6 MTYN




433 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:07:33 2016 done: Sat Nov  5 11:07:34 2016
 Total Scan time:  8.070 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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