Result of FASTA (omim) for pF1KB5815
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5815, 471 aa
  1>>>pF1KB5815 471 - 471 aa - 471 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2609+/-0.000488; mu= 11.6191+/- 0.031
 mean_var=324.9892+/-69.183, 0's: 0 Z-trim(117.8): 115  B-trim: 1806 in 1/58
 Lambda= 0.071144
 statistics sampled from 29926 (30059) to 29926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.352), width:  16
 Scan time:  8.710

The best scores are:                                      opt bits E(85289)
NP_001012496 (OMIM: 191318) splicing factor U2AF 6 ( 471) 3169 339.6 1.1e-92
NP_009210 (OMIM: 191318) splicing factor U2AF 65 k ( 475) 3151 337.7 4.1e-92
XP_011524712 (OMIM: 191318) PREDICTED: splicing fa ( 371) 2430 263.6 6.8e-70
XP_006723057 (OMIM: 191318) PREDICTED: splicing fa ( 311) 2039 223.3 7.5e-58


>>NP_001012496 (OMIM: 191318) splicing factor U2AF 65 kD  (471 aa)
 initn: 3169 init1: 3169 opt: 3169  Z-score: 1784.8  bits: 339.6 E(85289): 1.1e-92
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)

               10        20        30        40        50        60
pF1KB5 MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 SSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV
              370       380       390       400       410       420

              430       440       450       460       470 
pF1KB5 EVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
              430       440       450       460       470 

>>NP_009210 (OMIM: 191318) splicing factor U2AF 65 kDa s  (475 aa)
 initn: 3155 init1: 2295 opt: 3151  Z-score: 1774.8  bits: 337.7 E(85289): 4.1e-92
Smith-Waterman score: 3151; 99.2% identity (99.2% similar) in 475 aa overlap (1-471:1-475)

               10        20        30        40        50        60
pF1KB5 MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 APGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK
              250       260       270       280       290       300

              310       320       330       340           350      
pF1KB5 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATL----STINQTPVTLQV
       ::::::::::::::::::::::::::::::::::::::::::::    ::::::::::::
NP_009 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQV
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB5 PGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP
              370       380       390       400       410       420

        420       430       440       450       460       470 
pF1KB5 VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
              430       440       450       460       470     

>>XP_011524712 (OMIM: 191318) PREDICTED: splicing factor  (371 aa)
 initn: 2434 init1: 1574 opt: 2430  Z-score: 1375.8  bits: 263.6 E(85289): 6.8e-70
Smith-Waterman score: 2430; 98.9% identity (98.9% similar) in 371 aa overlap (105-471:1-371)

           80        90       100       110       120       130    
pF1KB5 GLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTP
                                     ::::::::::::::::::::::::::::::
XP_011                               MQYKAMQAAGQIPATALLPTMTPDGLAVTP
                                             10        20        30

          140       150       160       170       180       190    
pF1KB5 TPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD
               40        50        60        70        80        90

          200       210       220       230       240       250    
pF1KB5 KNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVV
              100       110       120       130       140       150

          260       270       280       290       300       310    
pF1KB5 PDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD
              160       170       180       190       200       210

          320       330       340           350       360       370
pF1KB5 QAIAGLNGMQLGDKKLLVQRASVGAKNATL----STINQTPVTLQVPGLMSSQVQMGGHP
       ::::::::::::::::::::::::::::::    ::::::::::::::::::::::::::
XP_011 QAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHP
              220       230       240       250       260       270

              380       390       400       410       420       430
pF1KB5 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV
              280       290       300       310       320       330

              440       450       460       470 
pF1KB5 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
       :::::::::::::::::::::::::::::::::::::::::
XP_011 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
              340       350       360       370 

>>XP_006723057 (OMIM: 191318) PREDICTED: splicing factor  (311 aa)
 initn: 2043 init1: 1183 opt: 2039  Z-score: 1159.6  bits: 223.3 E(85289): 7.5e-58
Smith-Waterman score: 2039; 98.7% identity (98.7% similar) in 311 aa overlap (165-471:1-311)

          140       150       160       170       180       190    
pF1KB5 TPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD
                                     ::::::::::::::::::::::::::::::
XP_006                               MMDFFNAQMRLGGLTQAPGNPVLAVQINQD
                                             10        20        30

          200       210       220       230       240       250    
pF1KB5 KNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVV
               40        50        60        70        80        90

          260       270       280       290       300       310    
pF1KB5 PDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD
              100       110       120       130       140       150

          320       330       340           350       360       370
pF1KB5 QAIAGLNGMQLGDKKLLVQRASVGAKNATL----STINQTPVTLQVPGLMSSQVQMGGHP
       ::::::::::::::::::::::::::::::    ::::::::::::::::::::::::::
XP_006 QAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHP
              160       170       180       190       200       210

              380       390       400       410       420       430
pF1KB5 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV
              220       230       240       250       260       270

              440       450       460       470 
pF1KB5 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
       :::::::::::::::::::::::::::::::::::::::::
XP_006 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW
              280       290       300       310 




471 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:25:03 2016 done: Sat Nov  5 10:25:05 2016
 Total Scan time:  8.710 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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