Result of FASTA (ccds) for pF1KF0267
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KF0267, 1101 aa
  1>>>pF1KF0267 1101 - 1101 aa - 1101 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.2872+/-0.000986; mu= 0.9957+/- 0.059
 mean_var=297.8898+/-59.175, 0's: 0 Z-trim(114.9): 119  B-trim: 0 in 0/53
 Lambda= 0.074310
 statistics sampled from 15312 (15431) to 15312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.474), width:  16
 Scan time:  6.340

The best scores are:                                      opt bits E(32554)
CCDS30918.1 ARHGAP30 gene_id:257106|Hs108|chr1     (1101) 7429 810.7       0
CCDS72958.1 ARHGAP30 gene_id:257106|Hs108|chr1     ( 924) 6245 683.7  5e-196
CCDS1215.1 ARHGAP30 gene_id:257106|Hs108|chr1      ( 890) 4572 504.4 4.7e-142
CCDS54254.1 ARHGAP33 gene_id:115703|Hs108|chr19    (1123) 1076 129.6 3.8e-29
CCDS12477.1 ARHGAP33 gene_id:115703|Hs108|chr19    (1126) 1031 124.8 1.1e-27
CCDS31718.1 ARHGAP32 gene_id:9743|Hs108|chr11      (1738) 1027 124.5   2e-27
CCDS44769.1 ARHGAP32 gene_id:9743|Hs108|chr11      (2087) 1027 124.6 2.3e-27
CCDS43135.1 ARHGAP31 gene_id:57514|Hs108|chr3      (1444) 1000 121.6 1.3e-26


>>CCDS30918.1 ARHGAP30 gene_id:257106|Hs108|chr1          (1101 aa)
 initn: 7429 init1: 7429 opt: 7429  Z-score: 4317.8  bits: 810.7 E(32554):    0
Smith-Waterman score: 7429; 99.8% identity (99.9% similar) in 1101 aa overlap (1-1101:1-1101)

               10        20        30        40        50        60
pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS30 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 CTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL
       ::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 CTEGGDYCLIPRTSPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL
             1030      1040      1050      1060      1070      1080

             1090      1100 
pF1KF0 SSQRRSYAFETQANPGKGEGL
       :::::::::::::::::::::
CCDS30 SSQRRSYAFETQANPGKGEGL
             1090      1100 

>>CCDS72958.1 ARHGAP30 gene_id:257106|Hs108|chr1          (924 aa)
 initn: 6245 init1: 6245 opt: 6245  Z-score: 3632.8  bits: 683.7 E(32554): 5e-196
Smith-Waterman score: 6245; 99.6% identity (99.9% similar) in 924 aa overlap (178-1101:1-924)

       150       160       170       180       190       200       
pF1KF0 LMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFI
                                     ..::::::::::::::::::::::::::::
CCDS72                               MKSKDIEASGFNGTAAFMEVRVQSIVVEFI
                                             10        20        30

       210       220       230       240       250       260       
pF1KF0 LTHVDQLFGGAALSGGEVESGWRSLPGTRASGSPEDLMPRPLPYHLPSILQAGDGPPQMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LTHVDQLFGGAALSGGEVESGWRSLPGTRASGSPEDLMPRPLPYHLPSILQAGDGPPQMR
               40        50        60        70        80        90

       270       280       290       300       310       320       
pF1KF0 PYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPRGAEDREDKSNKGTLRPAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 PYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPRGAEDREDKSNKGTLRPAKS
              100       110       120       130       140       150

       330       340       350       360       370       380       
pF1KF0 MDSLSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGTNSEPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MDSLSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGTNSEPG
              160       170       180       190       200       210

       390       400       410       420       430       440       
pF1KF0 TPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 TPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGL
              220       230       240       250       260       270

       450       460       470       480       490       500       
pF1KF0 ECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQ
              280       290       300       310       320       330

       510       520       530       540       550       560       
pF1KF0 DSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 DSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFS
              340       350       360       370       380       390

       570       580       590       600       610       620       
pF1KF0 VEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEVEEENGEEVFLSAYDDLSPLLGPKPPIW
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
CCDS72 VEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEVEEENGEEVFLSAYDDLSPLLGPKPPIW
              400       410       420       430       440       450

       630       640       650       660       670       680       
pF1KF0 KGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 KGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGK
              460       470       480       490       500       510

       690       700       710       720       730       740       
pF1KF0 ASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKE
              520       530       540       550       560       570

       750       760       770       780       790       800       
pF1KF0 KEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 KEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGY
              580       590       600       610       620       630

       810       820       830       840       850       860       
pF1KF0 HEARKDQGDGEDSRSPEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEGSGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 HEARKDQGDGEDSRSPEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEGSGV
              640       650       660       670       680       690

       870       880       890       900       910       920       
pF1KF0 ASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEPEGQPSPDGCLCPCSLGLGGVGMRLAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEPEGQPSPDGCLCPCSLGLGGVGMRLAST
              700       710       720       730       740       750

       930       940       950       960       970       980       
pF1KF0 LVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRS
              760       770       780       790       800       810

       990      1000      1010      1020      1030      1040       
pF1KF0 SWRNGGSLSFDAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTPPCSMISAHSPRPL
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
CCDS72 SWRNGGSLSFDAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTSPCSMISAHSPRPL
              820       830       840       850       860       870

      1050      1060      1070      1080      1090      1100 
pF1KF0 SCLELPSEGAEGSGSRSRLSLPPREPQVPDPLLSSQRRSYAFETQANPGKGEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SCLELPSEGAEGSGSRSRLSLPPREPQVPDPLLSSQRRSYAFETQANPGKGEGL
              880       890       900       910       920    

>>CCDS1215.1 ARHGAP30 gene_id:257106|Hs108|chr1           (890 aa)
 initn: 4681 init1: 4572 opt: 4572  Z-score: 2663.7  bits: 504.4 E(32554): 4.7e-142
Smith-Waterman score: 5624; 80.6% identity (80.7% similar) in 1101 aa overlap (1-1101:1-890)

               10        20        30        40        50        60
pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS12 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS
       :::::::::::::::::.:                                         
CCDS12 KQAEPGGRLDIREEAEGTP-----------------------------------------
              670                                                  

              730       740       750       760       770       780
pF1KF0 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE
                                                                   
CCDS12 ------------------------------------------------------------
                                                                   

              790       800       810       820       830       840
pF1KF0 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES
                                                                   
CCDS12 ------------------------------------------------------------
                                                                   

              850       860       870       880       890       900
pF1KF0 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP
                                                         ::::::::::
CCDS12 --------------------------------------------------QPPQPEEMEP
                                                       680         

              910       920       930       940       950       960
pF1KF0 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA
     690       700       710       720       730       740         

              970       980       990      1000      1010      1020
pF1KF0 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT
     750       760       770       780       790       800         

             1030      1040      1050      1060      1070      1080
pF1KF0 CTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL
       ::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CTEGGDYCLIPRTSPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL
     810       820       830       840       850       860         

             1090      1100 
pF1KF0 SSQRRSYAFETQANPGKGEGL
       :::::::::::::::::::::
CCDS12 SSQRRSYAFETQANPGKGEGL
     870       880       890

>>CCDS54254.1 ARHGAP33 gene_id:115703|Hs108|chr19         (1123 aa)
 initn: 1114 init1: 996 opt: 1076  Z-score: 636.8  bits: 129.6 E(32554): 3.8e-29
Smith-Waterman score: 1123; 38.2% identity (57.8% similar) in 702 aa overlap (3-679:162-807)

                                           10        20        30  
pF1KF0                             MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQE
                                     :::. ...:  ..::::::: :::..:::.
CCDS54 PQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQD
             140       150       160       170       180       190 

             40        50        60        70        80        90  
pF1KF0 VPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSS
       :::::. :.::.: .:::::::::::::::::.::.::.::: :.:   ..::::: :::
CCDS54 VPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSS
             200       210       220       230       240       250 

            100       110       120       130       140       150  
pF1KF0 LCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHL
       ::: ::::::.:::::.:: ::.::..:  : ::::.. .:...:: :.:::::.:.:::
CCDS54 LCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHL
             260       270       280       290       300       310 

            160       170       180       190       200       210  
pF1KF0 VHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVD
       ..::  ::.:.::::::::::::::::: ..:. :..:.::: ::::::.::::.:::::
CCDS54 ARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVD
             320       330       340       350       360       370 

            220       230        240       250       260        270
pF1KF0 QLFGGAALSGGEVESGWRSLPGTRA-SGSPEDLMPRPLPYHLPSILQAGD-GPPQMRPYH
        ::. .  :.:   .:   ::  .. .::  .   : :  .  .    :  : :      
CCDS54 VLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPST--RLLTLEEAQARTQGRLGTPTEPTTP
             380       390       400         410       420         

              280              290       300        310       320  
pF1KF0 TIIEIAEHKRKG--SLKVRK-----WRSIFNLGRSGHETKRK-LPRGAEDREDKSNKG--
              ..:::  . : ::     :...: :::.    ..: ::  .  :   . .:  
CCDS54 KAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGSR
     430       440       450       460       470       480         

                  330         340        350       360       370   
pF1KF0 ----TLRPAKSMDSLSA-AAGAS-DEPEGLVGP-SSPRPSPLLPESLENDSIEAAEGEQE
           ::: ::: .:::. :.::. .. . :  : ::    :. :      : :.  . . 
CCDS54 PDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPA--PAGSCESLSSSSS
     490       500       510       520       530         540       

           380       390       400       410       420       430   
pF1KF0 PEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPN
        :. .  ...:   .  :: .:.  .::   .  : .  .:  . .           :: 
CCDS54 SESSSSESSSSSSESSAAGLGAL--SGSPSHRTSAWLDDGDELDFS-----------PPR
       550       560       570         580       590               

           440       450       460       470       480       490   
pF1KF0 IISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDD
        . ..      :::.   :  : :  .   :.:  .:.::       :  .: : :    
CCDS54 CLEGL------RGLDFDPLTFRCSSPTPGDPAPPASPAPPAPASAFPPRVTPQAISPRGP
                600       610       620       630       640        

           500       510       520          530       540          
pF1KF0 LAPALEDSLSQEVQDSFSFLEDSSSSEP---EWVGAEDGEVAQAEAAGAAFSPGED-DPG
        .::   .:  .... ..      :  :   : .::  :  :.:  .  :.:::..  : 
CCDS54 TSPASPAAL--DISEPLAV-----SVPPAVLELLGA-GGAPASATPT-PALSPGRSLRP-
      650         660            670        680        690         

     550       560       570       580       590         600       
pF1KF0 MGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSA-GPR-PEVEEENGEE
         .:  ::  :       .: :: :   .:        : .. .: ::  :..:      
CCDS54 --HLIPLLLRG-------AEAPLTDACQQEM-------CSKLRGAQGPLGPDMESPLPPP
        700              710       720              730       740  

       610       620       630       640       650       660       
pF1KF0 VFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGG
         ::    : :  .: ::  :. . : . : .   : ...   .: :  .   .:. :  
CCDS54 P-LSL---LRPGGAPPPPP-KNPARLMALALAERAQQVAEQQSQQECGGTPPASQS-PFH
                750        760       770       780       790       

       670       680       690       700       710       720       
pF1KF0 RLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKAD
       : ..  :. : :                                                
CCDS54 R-SLSLEVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPMGTSRR
         800       810       820       830       840       850     

>>CCDS12477.1 ARHGAP33 gene_id:115703|Hs108|chr19         (1126 aa)
 initn: 1116 init1: 996 opt: 1031  Z-score: 610.7  bits: 124.8 E(32554): 1.1e-27
Smith-Waterman score: 1098; 37.3% identity (57.9% similar) in 689 aa overlap (3-647:298-963)

                                           10        20        30  
pF1KF0                             MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQE
                                     :::. ...:  ..::::::: :::..:::.
CCDS12 PQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQD
       270       280       290       300       310       320       

             40        50        60        70        80        90  
pF1KF0 VPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSS
       :::::. :.::.: .:::::::::::::::::.::.::.::: :.:   ..::::: :::
CCDS12 VPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSS
       330       340       350       360       370       380       

            100       110       120       130       140       150  
pF1KF0 LCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHL
       ::: ::::::.:::::.:: ::.::..:  : ::::.. .:...:: :.:::::.:.:::
CCDS12 LCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHL
       390       400       410       420       430       440       

            160       170       180       190       200       210  
pF1KF0 VHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVD
       ..::  ::.:.::::::::::::::::: ..:. :..:.::: ::::::.::::.:::::
CCDS12 ARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVD
       450       460       470       480       490       500       

            220       230        240        250       260          
pF1KF0 QLFGGAALSGGEVESGWRSLPGTRA-SGS-PEDLMPRPLPYHLPSILQAGD-GPPQMRPY
        ::. .  :.:   .:   ::  .. .:: :     : :  .  .    :  : :     
CCDS12 VLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPST---RLLTLEEAQARTQGRLGTPTEPTT
       510       520       530       540          550       560    

     270       280              290       300        310       320 
pF1KF0 HTIIEIAEHKRKG--SLKVRK-----WRSIFNLGRSGHETKRK-LPRGAEDREDKSNKG-
               ..:::  . : ::     :...: :::.    ..: ::  .  :   . .: 
CCDS12 PKAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGS
          570       580       590       600       610       620    

                   330                  340        350         360 
pF1KF0 -----TLRPAKSMDSLSAAAG-----------ASDEPEGLVGPS-SPRPS--PLLPESLE
            ::: ::: .:::. :.           ::  :   ..:. : ::   ::: .. :
CCDS12 RPDTVTLRSAKSEESLSSQASGAELLGAGGAPASATPTPALSPGRSLRPHLIPLLLRGAE
          630       640       650       660       670       680    

             370        380         390       400            410   
pF1KF0 NDSIEAAEGEQEPEAE-ALG--GTNSEPGTPRAGRSAIRAGGS-----SRAERCAGVHIS
           .: . :.  . . : :  : . :   :    : .: ::.     .   :  .. ..
CCDS12 APLTDACQQEMCSKLRGAQGPLGPDMESPLPPPPLSLLRPGGAPPPPPKNPARLMALALA
          690       700       710       720       730       740    

            420       430         440       450       460       470
pF1KF0 D-PYNVNLPLHITSILSVPPNIIS--NVSLARLTRGLECPALQHRPSPASGPGPGPGLGP
       .   .:          ..::   :  . ::.  . :    .    : : :   ::  . :
CCDS12 ERAQQVAEQQSQQECGGTPPASQSPFHRSLSLEVGGEPLGTSGSGPPPNSLAHPGAWV-P
          750       760       770       780       790       800    

              480       490       500       510       520          
pF1KF0 GPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSE-PEWVGAEDG
       :::    . .  .: : .. :   .   . .:   .: : ..   ... . :: ..    
CCDS12 GPPPYLPRQQSDGSLLRSQRPMGTS---RRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPC
           810       820          830       840       850       860

     530       540       550       560       570       580         
pF1KF0 EVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCC
        : .   . . :::.  .     :  .::: :.   . . ::    :.. .    .:.  
CCDS12 SVPSQVPTPGFFSPAPRE----CLPPFLGV-PKPGLYPLGPP----SFQPS----SPAPV
              870           880        890           900           

     590       600       610        620       630       640        
pF1KF0 SVDSAGPRPEVEEENGEEVFLS-AYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQG
         .: ::   ...  ::...   . .. ::  ::    :.   :.  .  . .   ::: 
CCDS12 WRSSLGPPAPLDR--GENLYYEIGASEGSPYSGPTRS-WSPFRSMPPDRLNASYGMLGQS
       910       920         930       940        950       960    

      650       660       670       680       690       700        
pF1KF0 GEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREG
                                                                   
CCDS12 PPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQHPARRPTPPEPLYVNLALGPRGPSPASSS
          970       980       990      1000      1010      1020    

>>CCDS31718.1 ARHGAP32 gene_id:9743|Hs108|chr11           (1738 aa)
 initn: 1248 init1: 1001 opt: 1027  Z-score: 605.8  bits: 124.5 E(32554): 2e-27
Smith-Waterman score: 1198; 39.5% identity (62.0% similar) in 663 aa overlap (1-619:1-628)

                  10        20        30        40        50       
pF1KF0 MKSR---QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS
       ::::   :: :..:  ::::::::: ::: .:: ::::::.::. :.:.::.::::::::
CCDS31 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KF0 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA
       ::.::::.::.::.::. ::: .. :.:::: :.:::: ::::::.:::::.::.::..:
CCDS31 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KF0 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL
       :..  . :::.:: .:...:: :.:::::::::::  .:.. . :::::.::::::::::
CCDS31 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL
              130       140       150       160       170       180

       180       190       200       210           220       230   
pF1KF0 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGG----AALSGGEVESGWRSL-
       ::::.::.. :.:::::::::.::.::::::.::: ::.:    :   :.   :  .:: 
CCDS31 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL
              190       200       210       220       230       240

               240       250            260        270       280   
pF1KF0 ---PGTRASGSPEDLMPRPLPYHLPSI-----LQAGDGPPQMR-PYHTIIEIAEHKRKGS
          :.:.     :         . : .     ...:.::  ..  .:::::.  .... .
CCDS31 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ
              250       260       270       280       290       300

                290       300        310              320       330
pF1KF0 LKVRK-----WRSIFNLGRSGHETKRKLPRG-AEDREDKS-------NKGTLRPAKSMDS
        :..:     :::.::::.:.  .:::: :. .:  : :.        .:::: ::: .:
CCDS31 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES
              310       320       330       340       350       360

              340       350       360       370       380          
pF1KF0 LSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGT-NSEPGTP
       :..   : :    :  :  :: :        .:.. :. .     .: ::.  ::  . :
CCDS31 LTSLH-AVDGDSKLFRPRRPRSS--------SDALSASFN-----GEMLGNRCNSYDNLP
               370       380               390            400      

     390       400       410       420       430       440         
pF1KF0 RAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGLEC
       . ..:  . ::         .::  :  .. :    ..   ::.: . .::     ...:
CCDS31 HDNESE-EEGGL--------LHI--PALMS-PHSAEDVDLSPPDI-GVASLDFDPMSFQC
        410                420          430        440       450   

      450       460         470            480       490       500 
pF1KF0 -PALQHRPSPASGPG--PGPGLGPGPP-----DEKLEASPASSPLADSGPDDLAPALEDS
        :   .     :: .   .:: .   :     : .  .:  ..: . .. . ..: :...
CCDS31 SPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSP-LQEK
           460       470       480       490       500        510  

             510       520       530       540       550        560
pF1KF0 LSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEEL-LGVG
       ::     ..:  ::.::.   ..  :    : .   :  .:    .:.:.  : . . . 
CCDS31 LSPFFTLDLSPTEDKSSKPSSFT--EKVVYAFSPKIGRKLS---KSPSMSISEPISVTLP
            520       530         540       550          560       

              570       580       590          600       610       
pF1KF0 PQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSA---GPRPEVEEENGEEVFLSAYD-DL
       :.: :  :   ... . ..:.     .:    .:   .:   :. ...: :   ::. ..
CCDS31 PRVSE--VIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEV
       570         580       590       600       610       620     

        620       630       640       650       660       670      
pF1KF0 SPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAE
       .::                                                         
CCDS31 QPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPP
         630       640       650       660       670       680     

>>CCDS44769.1 ARHGAP32 gene_id:9743|Hs108|chr11           (2087 aa)
 initn: 1248 init1: 1001 opt: 1027  Z-score: 604.7  bits: 124.6 E(32554): 2.3e-27
Smith-Waterman score: 1198; 39.5% identity (62.0% similar) in 663 aa overlap (1-619:350-977)

                                                10        20       
pF1KF0                               MKSR---QKGKKKGSAKERVFGCDLQEHLQ
                                     ::::   :: :..:  ::::::::: ::: 
CCDS44 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
     320       330       340       350       360       370         

        30        40        50        60        70        80       
pF1KF0 HSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDI
       .:: ::::::.::. :.:.::.::::::::::.::::.::.::.::. ::: .. :.:::
CCDS44 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
     380       390       400       410       420       430         

        90       100       110       120       130       140       
pF1KF0 HCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEF
       : :.:::: ::::::.:::::.::.::..::..  . :::.:: .:...:: :.::::::
CCDS44 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
     440       450       460       470       480       490         

       150       160       170       180       190       200       
pF1KF0 LMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFI
       :::::  .:.. . :::::.::::::::::::::.::.. :.:::::::::.::.:::::
CCDS44 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
     500       510       520       530       540       550         

       210           220       230           240       250         
pF1KF0 LTHVDQLFGG----AALSGGEVESGWRSL----PGTRASGSPEDLMPRPLPYHLPSI---
       :.::: ::.:    :   :.   :  .::    :.:.     :         . : .   
CCDS44 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
     560       570       580       590       600       610         

          260        270       280            290       300        
pF1KF0 --LQAGDGPPQMR-PYHTIIEIAEHKRKGSLKVRK-----WRSIFNLGRSGHETKRKLPR
         ...:.::  ..  .:::::.  .... . :..:     :::.::::.:.  .:::: :
CCDS44 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
     620       630       640       650       660       670         

       310              320       330       340       350       360
pF1KF0 G-AEDREDKS-------NKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL
       . .:  : :.        .:::: ::: .::..   : :    :  :  :: :       
CCDS44 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLH-AVDGDSKLFRPRRPRSS-------
     680       690       700       710        720       730        

              370       380        390       400       410         
pF1KF0 ENDSIEAAEGEQEPEAEALGGT-NSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVN
        .:.. :. .     .: ::.  ::  . :. ..:  . ::         .::  :  ..
CCDS44 -SDALSASFN-----GEMLGNRCNSYDNLPHDNESE-EEGGL--------LHI--PALMS
              740            750       760                  770    

     420       430       440        450       460         470      
pF1KF0 LPLHITSILSVPPNIISNVSLARLTRGLEC-PALQHRPSPASGPG--PGPGLGPGPP---
        :    ..   ::.: . .::     ...: :   .     :: .   .:: .   :   
CCDS44 -PHSAEDVDLSPPDI-GVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKPSAN
           780        790       800       810       820       830  

             480       490       500       510       520       530 
pF1KF0 --DEKLEASPASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEV
         : .  .:  ..: . .. . ..: :...::     ..:  ::.::.   ..  :    
CCDS44 KKDAETGSSQCQTPGSTASSEPVSP-LQEKLSPFFTLDLSPTEDKSSKPSSFT--EKVVY
            840       850        860       870       880           

             540       550        560       570       580       590
pF1KF0 AQAEAAGAAFSPGEDDPGMGYLEEL-LGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCS
       : .   :  .:    .:.:.  : . . . :.: :  :   ... . ..:.     .:  
CCDS44 AFSPKIGRKLS---KSPSMSISEPISVTLPPRVSE--VIGTVSNTTAQNASSSTWDKCVE
     890       900          910       920         930       940    

                 600       610        620       630       640      
pF1KF0 VDSA---GPRPEVEEENGEEVFLSAYD-DLSPLLGPKPPIWKGSGSLEGEAAGCGRQALG
         .:   .:   :. ...: :   ::. ...::                           
CCDS44 ERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVA
          950       960       970       980       990      1000    

        650       660       670       680       690       700      
pF1KF0 QGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLR
                                                                   
CCDS44 SGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGT
         1010      1020      1030      1040      1050      1060    

>>CCDS43135.1 ARHGAP31 gene_id:57514|Hs108|chr3           (1444 aa)
 initn: 1262 init1: 970 opt: 1000  Z-score: 591.3  bits: 121.6 E(32554): 1.3e-26
Smith-Waterman score: 1223; 30.2% identity (55.9% similar) in 1142 aa overlap (3-1004:6-1116)

                  10        20        30        40        50       
pF1KF0    MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS
            ..:: :.::.:.  .::::: :.:. :::.:: ::::::::.: .:.::::::::
CCDS43 MKNKGAKQKLKRKGAAS--AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLS
               10          20        30        40        50        

        60        70        80        90       100       110       
pF1KF0 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA
       ::.::::.::::: :.. ::: :.:::::::::.:::: ::::::.:::::.::.::.::
CCDS43 GVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEA
       60        70        80        90       100       110        

       120       130       140       150       160       170       
pF1KF0 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL
       :.   :  .:..: .:..:::  .:::::.:.:::.:.::::..:::::::::.::::::
CCDS43 VSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL
      120       130       140       150       160       170        

       180       190       200       210          220       230    
pF1KF0 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAA---LSGGEVESGWRSL--
       ::::.:::.: :: :::. ::::..:.::::.::::.:...:   : . : .   .::  
CCDS43 LRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIMKSLTL
      180       190       200       210       220       230        

               240       250       260             270       280   
pF1KF0 PGTRASG---SPEDLMPRPLPYHLPSILQAGDG------PPQMRPYHTIIEIAEHKRKGS
       :.        : :. . : :  . :.  .  ..      ::.   .::..:. ..::: :
CCDS43 PALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPMGTLFHTVLELPDNKRKLS
      240       250       260       270       280       290        

           290       300       310           320       330         
pF1KF0 LKVRKWRSIFNLGRSGHETKRKLPRGA----EDREDKSNKGTLRPAKSMDSLSAAAGASD
        : .::.::::::::: ..: :: :..    . .. . .:.:.::::::::: ..   . 
CCDS43 SKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGK
      300       310       320       330       340       350        

     340       350       360              370                      
pF1KF0 EPEGLVGPSSPRPSPLLPESLENDS-------IEAAEGE--QE---PEAEA---------
       : .:  . .    . ..: .  ...       .   :::  ::   : ::.         
CCDS43 ETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLTKQEGEWGQEGMPPGAEGGFDVSSDRS
      360       370       380       390       400       410        

       380                  390       400                          
pF1KF0 -LGGTNSEPGT-----------PRAGRSAIRAGG-----------------------SSR
        : :....:             :.. ..: .  :                       : :
CCDS43 HLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGMFYTSNDSPSKSVFTSSLFQMEPSPR
      420       430       440       450       460       470        

           410       420       430               440        450    
pF1KF0 AERCAGVHISDPYNVNLPLHITSILSV-------PPNIISNVS-LARLT-RGLECPALQH
        .: : ..::.:. :..::......:.       ::. ....: : ... .: :  .  .
CCDS43 NQRKA-LNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFHGSESGGWPE
      480        490       500       510       520       530       

          460       470          480       490       500       510 
pF1KF0 RPSPASGPGPGPGLGP--GPPDEK-LEASPASSPLADSGPDDLAPALEDSLSQEVQDSFS
       . .: ..   . ..    :  : : .  .:..   . .  .. .  ::.. . : . : .
CCDS43 EEKPLGAETSAASVPKKAGLEDAKAVPEAPGTVECSKGLSQEPGAHLEEKKTPESSLSSQ
       540       550       560       570       580       590       

              520       530       540                   550        
pF1KF0 FLED-SSSSEPEWVGAEDGEVAQAEAAGAAFSP------------GEDDPGMGYL----E
        :..  .  .:: :  :  :... :..    ::             ::: . . .    .
CCDS43 HLNELEKRPNPEKVVEEGREAGEMESSTLQESPRARAEAVLLHEMDEDDLANALIWPEIQ
       600       610       620       630       640       650       

          560       570       580       590       600       610    
pF1KF0 ELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEVEEENGEEVFLSAYD
       . : .  . ::.:  ::   :. .  : .:       .: ::    :  ..    :   .
CCDS43 QELKIIESEEELSSLPP-PALKTSPIQPILE------SSLGPFIPSEPPGS----LPCGS
       660       670        680             690       700          

          620          630       640             650       660     
pF1KF0 DLSPLLGPKPPIWK---GSGSLEGEAAGCGR------QALGQGGEEQACWEVGEDKQAEP
         .:.  :   .:    .. : .: ... .:      :.:       :  :.   ..: :
CCDS43 FPAPVSTPLE-VWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASP
        710        720       730       740       750       760     

         670       680                     690       700       710 
pF1KF0 GGRLDIREEAEGSPE--------------TKVEAGKASEDRGEAGGSQETKVRLREGSRE
        . ...   .. ::               : :  .:.. .: ... . .: . . . . .
CCDS43 QATVEVGGPGNLSPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQLKSQ
         770       780       790       800       810       820     

             720           730        740        750       760     
pF1KF0 ETEAKEEKSKGQ----KKADSMEAKGVEEPG-GDEY-TDEKEKEIEREEDEQREEAQVEA
       ..       .:.    ...:....:..   : :  . .  .: ::  .:.:.  .. :. 
CCDS43 DSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGFPSPTREVEIVSQEEEDVTHS-VQE
         830       840       850       860       870       880     

         770       780       790       800       810         820   
pF1KF0 GRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEARKD--QGDGEDSR-S
         : ..     ..:..  :.:.  :      .  ..   :  :.:. .  ::   ..: :
CCDS43 PSDCDEDDTVTDIAQHGLEMVEPWEEPQWVTSPLHSPTLKDAHKAQVQGLQGHQLEKRLS
          890       900       910       920       930       940    

            830       840       850       860         870       880
pF1KF0 PEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEG--SGVASLEVDCAKEGNP
        . . . . .  ::   ...   :  . ..   :: .  :.     .   :.    :   
CCDS43 HRPSLRQSHSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKAL
          950       960       970       980       990      1000    

               890       900        910        920       930       
pF1KF0 HS-SEMEEVAPQPPQPEEMEPEG-QPSPDGCLCPCSLGLGG-VGMRLASTLVQVQQVRSV
       .:  :.  .      :..  : : ::.: .   : ::. :  .: .:. .  :..:  .:
CCDS43 RSFREFSGLKGAEAPPNQKGPSGVQPNP-AETSPISLAEGKELGTHLGHSSPQIRQ-GGV
         1010      1020      1030       1040      1050       1060  

       940       950       960       970       980       990       
pF1KF0 PVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSF
       :   :. .  . ::.. :      ..:  .:..:.    : .  .  .: :     ::..
CCDS43 P--GPESSKESSPSVQDS------TSPGEHPAKLQLKSTECGPPKGKNRPS-----SLNL
             1070            1080      1090      1100              

      1000      1010      1020      1030      1040      1050       
pF1KF0 DAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGA
       : :. .:                                                     
CCDS43 DPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMTSSYCKADPWRVYSQDPQDLDIVA
    1110      1120      1130      1140      1150      1160         




1101 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:08:52 2016 done: Fri Nov  4 20:08:53 2016
 Total Scan time:  6.340 Total Display time:  0.340

Function used was FASTA [36.3.4 Apr, 2011]
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