Result of FASTA (omim) for pF1KB9852
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9852, 382 aa
  1>>>pF1KB9852 382 - 382 aa - 382 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7317+/-0.000318; mu= 15.4452+/- 0.020
 mean_var=83.8728+/-16.419, 0's: 0 Z-trim(117.1): 47  B-trim: 359 in 1/54
 Lambda= 0.140044
 statistics sampled from 28682 (28729) to 28682 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.337), width:  16
 Scan time:  9.020

The best scores are:                                      opt bits E(85289)
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 2573 529.4 5.4e-150
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333)  995 210.5 4.5e-54
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333)  995 210.5 4.5e-54
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333)  995 210.5 4.5e-54
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap  ( 435)  942 199.9 9.4e-51
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435)  942 199.9 9.4e-51
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427)  900 191.4 3.3e-48
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433)  900 191.4 3.4e-48
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433)  900 191.4 3.4e-48
NP_859054 (OMIM: 108770,121013,612474,614049) gap  ( 358)  883 187.9 3.1e-47
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358)  883 187.9 3.1e-47
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358)  883 187.9 3.1e-47
NP_005257 (OMIM: 108770,121013,612474,614049) gap  ( 358)  883 187.9 3.1e-47
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543)  847 180.8 6.7e-45
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515)  832 177.7 5.3e-44
NP_076872 (OMIM: 133200,220290,603324,612644) gap  ( 270)  436 97.5 3.8e-20
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270)  436 97.5 3.8e-20
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226)  433 96.9   5e-20
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226)  433 96.9   5e-20
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  426 95.5 1.6e-19
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283)  426 95.5 1.6e-19
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283)  426 95.5 1.6e-19
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  426 95.5 1.6e-19
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261)  413 92.9 9.3e-19
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261)  413 92.9 9.3e-19
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap  ( 266)  407 91.7 2.2e-18
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266)  407 91.7 2.2e-18
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396)  405 91.4   4e-18
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396)  405 91.4   4e-18
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396)  405 91.4   4e-18
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396)  405 91.4   4e-18
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273)  392 88.7 1.8e-17
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273)  392 88.7 1.8e-17
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223)  390 88.2 2.1e-17
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223)  390 88.2 2.1e-17
NP_065168 (OMIM: 608803,608804,613206,613480) gap  ( 439)  385 87.4 7.1e-17
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294)  367 83.6 6.4e-16
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321)  358 81.8 2.4e-15
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270)  328 75.7 1.4e-13
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279)  313 72.7 1.2e-12
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370)  259 61.9 2.9e-09


>>NP_000156 (OMIM: 104100,121014,133200,164200,186100,21  (382 aa)
 initn: 2573 init1: 2573 opt: 2573  Z-score: 2813.9  bits: 529.4 E(85289): 5.4e-150
Smith-Waterman score: 2573; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 YNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVD
              310       320       330       340       350       360

              370       380  
pF1KB9 QRPSSRASSRASSRPRPDDLEI
       ::::::::::::::::::::::
NP_000 QRPSSRASSRASSRPRPDDLEI
              370       380  

>>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al  (333 aa)
 initn: 1039 init1: 967 opt: 995  Z-score: 1091.7  bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       : :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::..  .  
XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
        .:.  :  .: .  : .. : :....::.:. ::. :.: ::..:..::  :: .::..
XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
       .  :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... .    :.
XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
       . :    . : ..::.  .:  :   : . :.     :..  .: :::            
XP_005 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
              250         260               270                    

        300        310       320       330       340       350     
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
        : .::  ..::::::: ..:. :..        :   :. .    ::..:        :
XP_005 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
        280       290        300               310                 

         360       370       380  
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
            .:::: ::..            
XP_005 ----PSRPSSSASKKQYV         
         320       330            

>>XP_016856532 (OMIM: 121012) PREDICTED: gap junction al  (333 aa)
 initn: 1039 init1: 967 opt: 995  Z-score: 1091.7  bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
XP_016 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       : :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::..  .  
XP_016 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
        .:.  :  .: .  : .. : :....::.:. ::. :.: ::..:..::  :: .::..
XP_016 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
       .  :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... .    :.
XP_016 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
       . :    . : ..::.  .:  :   : . :.     :..  .: :::            
XP_016 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
              250         260               270                    

        300        310       320       330       340       350     
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
        : .::  ..::::::: ..:. :..        :   :. .    ::..:        :
XP_016 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
        280       290        300               310                 

         360       370       380  
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
            .:::: ::..            
XP_016 ----PSRPSSSASKKQYV         
         320       330            

>>NP_002051 (OMIM: 121012) gap junction alpha-4 protein   (333 aa)
 initn: 1039 init1: 967 opt: 995  Z-score: 1091.7  bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
NP_002 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       : :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::..  .  
NP_002 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
        .:.  :  .: .  : .. : :....::.:. ::. :.: ::..:..::  :: .::..
NP_002 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
       .  :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... .    :.
NP_002 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
       . :    . : ..::.  .:  :   : . :.     :..  .: :::            
NP_002 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
              250         260               270                    

        300        310       320       330       340       350     
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
        : .::  ..::::::: ..:. :..        :   :. .    ::..:        :
NP_002 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
        280       290        300               310                 

         360       370       380  
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
            .:::: ::..            
NP_002 ----PSRPSSSASKKQYV         
         320       330            

>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc  (435 aa)
 initn: 1117 init1: 583 opt: 942  Z-score: 1032.2  bits: 199.9 E(85289): 9.4e-51
Smith-Waterman score: 985; 42.2% identity (67.2% similar) in 412 aa overlap (1-382:1-398)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::.::...: .::. :::::.::::::::.::.:.:..:::::: : :::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       :::::::..:::::.:::.:::::::.:::.::.::....: ::: ...::: .. . . 
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
          .    .   .      ...:.:.: :.:::::...:.::..:::.:.  :...::: 
XP_011 SPKEPPQDNPSSR------DDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
              130             140       150       160       170    

              190       200       210       220       230          
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
       :. .: : : :::. ::::.::::::::::::::.:. .:: ::..:.... .:    ::
XP_011 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
          180       190       200       210       220       230    

        240               250       260       270           280    
pF1KB9 KDRVK--------GKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLS----PMSPP
        .:.         : .::     ..  ::   :   :  .   ..: .       : .::
XP_011 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPY--YAHTAAPLGQARAVGYPGAPP
          240       250       260       270         280       290  

               290        300           310       320       330    
pF1KB9 ---GYKLV--TGDRNNS-SCRNYNKQ----ASEQNWANYSAEQNRMGQAGSTISNSHAQP
           .::.  :  :... : . :: .     .:::::: .::..  .  .   ... : :
XP_011 PAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAP
            300       310       320       330       340       350  

          340       350           360       370       380          
pF1KB9 FDFPDDNQNSKKLAAGHELQ----PLAIVDQRPSSRASSRASSRPRPDDLEI        
             ...:  ::  :: .    :: ..:   ::  .:  .. :. ..  .        
XP_011 SPV---GSSSPPLA--HEAEAGAAPL-LLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ
               360         370        380       390       400      

XP_011 PPLPLGDPGRASKASRASSGRARPEDLAI
        410       420       430     

>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p  (435 aa)
 initn: 1117 init1: 583 opt: 942  Z-score: 1032.2  bits: 199.9 E(85289): 9.4e-51
Smith-Waterman score: 985; 42.2% identity (67.2% similar) in 412 aa overlap (1-382:1-398)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::.::...: .::. :::::.::::::::.::.:.:..:::::: : :::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       :::::::..:::::.:::.:::::::.:::.::.::....: ::: ...::: .. . . 
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
          .    .   .      ...:.:.: :.:::::...:.::..:::.:.  :...::: 
NP_068 SPKEPPQDNPSSR------DDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
              130             140       150       160       170    

              190       200       210       220       230          
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
       :. .: : : :::. ::::.::::::::::::::.:. .:: ::..:.... .:    ::
NP_068 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
          180       190       200       210       220       230    

        240               250       260       270           280    
pF1KB9 KDRVK--------GKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLS----PMSPP
        .:.         : .::     ..  ::   :   :  .   ..: .       : .::
NP_068 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPY--YAHTAAPLGQARAVGYPGAPP
          240       250       260       270         280       290  

               290        300           310       320       330    
pF1KB9 ---GYKLV--TGDRNNS-SCRNYNKQ----ASEQNWANYSAEQNRMGQAGSTISNSHAQP
           .::.  :  :... : . :: .     .:::::: .::..  .  .   ... : :
NP_068 PAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAP
            300       310       320       330       340       350  

          340       350           360       370       380          
pF1KB9 FDFPDDNQNSKKLAAGHELQ----PLAIVDQRPSSRASSRASSRPRPDDLEI        
             ...:  ::  :: .    :: ..:   ::  .:  .. :. ..  .        
NP_068 SPV---GSSSPPLA--HEAEAGAAPL-LLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ
               360         370        380       390       400      

NP_068 PPLPLGDPGRASKASRASSGRARPEDLAI
        410       420       430     

>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g  (427 aa)
 initn: 918 init1: 544 opt: 900  Z-score: 986.4  bits: 191.4 E(85289): 3.3e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       :::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...:  :
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
       .:      :  .:: . : .   : ...: ::::::  :.::..:::.:.. ....::: 
XP_011 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
     120         130        140       150       160       170      

              190       200       210       220       230       240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
       .  .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
XP_011 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
       :                                                           
XP_011 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
        240       250       260       270       280       290      

>>NP_005258 (OMIM: 116200,600897,612474) gap junction al  (433 aa)
 initn: 959 init1: 544 opt: 900  Z-score: 986.3  bits: 191.4 E(85289): 3.4e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       :::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...:  :
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
       .:      :  .:: . : .   : ...: ::::::  :.::..:::.:.. ....::: 
NP_005 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
     120         130        140       150       160       170      

              190       200       210       220       230       240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
       .  .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
NP_005 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
       :                                                           
NP_005 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
        240       250       260       270       280       290      

>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g  (433 aa)
 initn: 959 init1: 544 opt: 900  Z-score: 986.3  bits: 191.4 E(85289): 3.4e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
       :::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...:  :
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
       .:      :  .:: . : .   : ...: ::::::  :.::..:::.:.. ....::: 
XP_011 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
     120         130        140       150       160       170      

              190       200       210       220       230       240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
       .  .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
XP_011 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
       :                                                           
XP_011 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
        240       250       260       270       280       290      

>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 938 init1: 538 opt: 883  Z-score: 969.0  bits: 187.9 E(85289): 3.1e-47
Smith-Waterman score: 921; 40.6% identity (69.9% similar) in 389 aa overlap (1-382:1-358)

               10        20        30        40        50        60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
       ::::: ::..:..:. .::. :::::.::::::.:.::::.::.:::::. :::.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKE-EELKVAQTD
       :.:::::..:::::.:.:::::::::.:.:.:..:.....: .:: . .: :. : .. .
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 GVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGF
       :       .. :.. .. :   .:.. ..: :: ::. :::... .::.:.. :..:::.
NP_859 GSYEYPVAEKAELSCWEEG---NGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGI
              130          140       150       160       170       

     180       190       200       210       220       230         
pF1KB9 SLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDR
        :.....:.:.:::: :.:..::::::..::.:::.:. .:: :.. ::... .: ...:
NP_859 FLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR
       180       190       200       210       220       230       

      240       250       260       270       280        290       
pF1KB9 -VKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPM-SPPGYKLVTGDRNNSS
        :: ..   : ..  ::      . . .  ..:. :    . . . :: :. .   ::  
NP_859 FVKPRQ---HMAKCQLS------GPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNN--
       240          250             260       270       280        

       300       310       320           330       340       350   
pF1KB9 CRNYNKQASEQNWANYSAEQNRMGQAGST----ISNSHAQPFDFPDDNQNSKKLAAGHEL
             .::.::  :  .:: : ::  .     :.  ..:  . :.       .. ::.:
NP_859 ------MASQQNTDNLVTEQVR-GQEQTPGEGFIQVRYGQKPEVPNG------VSPGHRL
              290       300        310       320             330   

           360       370       380  
pF1KB9 QPLAIVDQRPSSRASSRASSRPRPDDLEI
             :.:  :.:::.:    : ::: .
NP_859 PHGYHSDKRRLSKASSKA----RSDDLSV
           340       350            




382 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:46:57 2016 done: Fri Nov  4 19:46:58 2016
 Total Scan time:  9.020 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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