Result of FASTA (omim) for pF1KB8955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8955, 332 aa
  1>>>pF1KB8955 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3550+/-0.000469; mu= 15.2893+/- 0.029
 mean_var=99.9815+/-26.001, 0's: 0 Z-trim(109.1): 540  B-trim: 1961 in 2/52
 Lambda= 0.128267
 statistics sampled from 16457 (17239) to 16457 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.547), E-opt: 0.2 (0.202), width:  16
 Scan time:  7.280

The best scores are:                                      opt bits E(85289)
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 2200 418.4  1e-116
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229) 1514 291.3 1.3e-78
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231) 1502 289.1 6.2e-78
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 1274 247.2 4.6e-65
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326)  903 178.4 1.8e-44
NP_001041695 (OMIM: 102775) adenosine receptor A1  ( 326)  903 178.4 1.8e-44
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116)  698 140.0 2.4e-33
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258)  562 115.2 1.5e-25
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258)  562 115.2 1.5e-25
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258)  562 115.2 1.5e-25
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318)  462 96.8 6.6e-20
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  356 77.3 6.5e-14
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415)  354 76.9 8.2e-14
NP_612200 (OMIM: 609333) trace amine-associated re ( 339)  352 76.5 9.3e-14
NP_001289608 (OMIM: 600445) adenosine receptor A3  ( 173)  348 75.4 9.8e-14
NP_001289607 (OMIM: 600445) adenosine receptor A3  ( 123)  342 74.1 1.7e-13
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic  ( 477)  333 73.1 1.3e-12
NP_778227 (OMIM: 608282) trace amine-associated re ( 348)  325 71.5   3e-12
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  324 71.4   4e-12
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  323 71.1   4e-12
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  323 71.1   4e-12
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  323 71.2 4.3e-12
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  323 71.2 4.4e-12
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  323 71.2 4.4e-12
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  323 71.2 4.4e-12
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  323 71.2 4.4e-12
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  323 71.2 4.4e-12
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444)  321 70.8 5.9e-12
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461)  321 70.9 6.1e-12
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478)  319 70.5 8.1e-12
NP_778237 (OMIM: 608923) trace amine-associated re ( 345)  317 70.0 8.4e-12
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin  ( 528)  319 70.5 8.7e-12
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403)  316 69.9 1.1e-11
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426)  316 69.9 1.1e-11
NP_149421 (OMIM: 114610) cannabinoid receptor 1 is ( 439)  314 69.5 1.4e-11
XP_016865728 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
NP_057167 (OMIM: 114610) cannabinoid receptor 1 is ( 472)  314 69.6 1.5e-11
NP_001153731 (OMIM: 114610) cannabinoid receptor 1 ( 472)  314 69.6 1.5e-11
XP_011533726 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
XP_011533730 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
NP_001153730 (OMIM: 114610) cannabinoid receptor 1 ( 472)  314 69.6 1.5e-11
NP_001153698 (OMIM: 114610) cannabinoid receptor 1 ( 472)  314 69.6 1.5e-11
XP_011533728 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
XP_006715393 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
XP_016865729 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11
XP_016865727 (OMIM: 114610) PREDICTED: cannabinoid ( 472)  314 69.6 1.5e-11


>>NP_000667 (OMIM: 600446) adenosine receptor A2b [Homo   (332 aa)
 initn: 2200 init1: 2200 opt: 2200  Z-score: 2216.3  bits: 418.4 E(85289): 1e-116
Smith-Waterman score: 2200; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
              250       260       270       280       290       300

              310       320       330  
pF1KB8 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
       ::::::::::::::::::::::::::::::::
NP_000 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
              310       320       330  

>>XP_011521961 (OMIM: 600446) PREDICTED: adenosine recep  (229 aa)
 initn: 1514 init1: 1514 opt: 1514  Z-score: 1532.2  bits: 291.3 E(85289): 1.3e-78
Smith-Waterman score: 1514; 100.0% identity (100.0% similar) in 222 aa overlap (111-332:8-229)

               90       100       110       120       130       140
pF1KB8 LACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTP
                                     ::::::::::::::::::::::::::::::
XP_011                        MSERSRTLRYKSLVTGTRARGVIAVLWVLAFGIGLTP
                                      10        20        30       

              150       160       170       180       190       200
pF1KB8 FLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLV
        40        50        60        70        80        90       

              210       220       230       240       250       260
pF1KB8 IYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQ
       100       110       120       130       140       150       

              270       280       290       300       310       320
pF1KB8 PAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNG
       160       170       180       190       200       210       

              330  
pF1KB8 QAGVQPALGVGL
       ::::::::::::
XP_011 QAGVQPALGVGL
       220         

>>XP_016879686 (OMIM: 600446) PREDICTED: adenosine recep  (231 aa)
 initn: 1502 init1: 1502 opt: 1502  Z-score: 1520.2  bits: 289.1 E(85289): 6.2e-78
Smith-Waterman score: 1502; 100.0% identity (100.0% similar) in 220 aa overlap (113-332:12-231)

             90       100       110       120       130       140  
pF1KB8 CFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFL
                                     ::::::::::::::::::::::::::::::
XP_016                    MKAAHVVLSAWYKSLVTGTRARGVIAVLWVLAFGIGLTPFL
                                  10        20        30        40 

            150       160       170       180       190       200  
pF1KB8 GWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIY
              50        60        70        80        90       100 

            210       220       230       240       250       260  
pF1KB8 IKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPA
             110       120       130       140       150       160 

            270       280       290       300       310       320  
pF1KB8 QGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQA
             170       180       190       200       210       220 

            330  
pF1KB8 GVQPALGVGL
       ::::::::::
XP_016 GVQPALGVGL
             230 

>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1234 init1: 824 opt: 1274  Z-score: 1289.0  bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
              ..:...::.::.:.. :::::: ::   ..::. ::::.:::::::.:::..:
NP_001  MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       :::::::: :::.  .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
      60        70        80        90       100       110         

              130       140       150       160          170       
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
       ::.:.::. :::.:.:::::.::::       :: .: .: .. . :    : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
     120       130       140              150       160       170  

       180       190       200       210           220       230   
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
       ::.::::::::.::: :::.:: .:..:::.: :::.. : .    ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
            180       190       200       210       220       230  

           240       250       260       270       280       290   
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
       ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
            240       250       260        270       280       290 

           300       310        320       330                      
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL                    
        :.:: ::.:::  ..: : .  :... .: :  : :                       
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
             300       310       320       330       340       350 

NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
             360       370       380       390       400       410 

>>NP_000666 (OMIM: 102776) adenosine receptor A2a [Homo   (412 aa)
 initn: 1234 init1: 824 opt: 1274  Z-score: 1289.0  bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
              ..:...::.::.:.. :::::: ::   ..::. ::::.:::::::.:::..:
NP_000  MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       :::::::: :::.  .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_000 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
      60        70        80        90       100       110         

              130       140       150       160          170       
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
       ::.:.::. :::.:.:::::.::::       :: .: .: .. . :    : ::::.::
NP_000 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
     120       130       140              150       160       170  

       180       190       200       210           220       230   
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
       ::.::::::::.::: :::.:: .:..:::.: :::.. : .    ...:.:::.:.:::
NP_000 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
            180       190       200       210       220       230  

           240       250       260       270       280       290   
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
       ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_000 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
            240       250       260        270       280       290 

           300       310        320       330                      
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL                    
        :.:: ::.:::  ..: : .  :... .: :  : :                       
NP_000 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
             300       310       320       330       340       350 

NP_000 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
             360       370       380       390       400       410 

>>NP_001265428 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1234 init1: 824 opt: 1274  Z-score: 1289.0  bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
              ..:...::.::.:.. :::::: ::   ..::. ::::.:::::::.:::..:
NP_001  MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       :::::::: :::.  .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
      60        70        80        90       100       110         

              130       140       150       160          170       
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
       ::.:.::. :::.:.:::::.::::       :: .: .: .. . :    : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
     120       130       140              150       160       170  

       180       190       200       210           220       230   
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
       ::.::::::::.::: :::.:: .:..:::.: :::.. : .    ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
            180       190       200       210       220       230  

           240       250       260       270       280       290   
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
       ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
            240       250       260        270       280       290 

           300       310        320       330                      
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL                    
        :.:: ::.:::  ..: : .  :... .: :  : :                       
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
             300       310       320       330       340       350 

NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
             360       370       380       390       400       410 

>>NP_001265426 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1234 init1: 824 opt: 1274  Z-score: 1289.0  bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
              ..:...::.::.:.. :::::: ::   ..::. ::::.:::::::.:::..:
NP_001  MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       :::::::: :::.  .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
      60        70        80        90       100       110         

              130       140       150       160          170       
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
       ::.:.::. :::.:.:::::.::::       :: .: .: .. . :    : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
     120       130       140              150       160       170  

       180       190       200       210           220       230   
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
       ::.::::::::.::: :::.:: .:..:::.: :::.. : .    ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
            180       190       200       210       220       230  

           240       250       260       270       280       290   
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
       ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
            240       250       260        270       280       290 

           300       310        320       330                      
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL                    
        :.:: ::.:::  ..: : .  :... .: :  : :                       
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
             300       310       320       330       340       350 

NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
             360       370       380       390       400       410 

>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1234 init1: 824 opt: 1274  Z-score: 1289.0  bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)

               10        20        30        40        50        60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
              ..:...::.::.:.. :::::: ::   ..::. ::::.:::::::.:::..:
NP_001  MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
       :::::::: :::.  .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
      60        70        80        90       100       110         

              130       140       150       160          170       
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
       ::.:.::. :::.:.:::::.::::       :: .: .: .. . :    : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
     120       130       140              150       160       170  

       180       190       200       210           220       230   
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
       ::.::::::::.::: :::.:: .:..:::.: :::.. : .    ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
            180       190       200       210       220       230  

           240       250       260       270       280       290   
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
       ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
            240       250       260        270       280       290 

           300       310        320       330                      
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL                    
        :.:: ::.:::  ..: : .  :... .: :  : :                       
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
             300       310       320       330       340       350 

NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
             360       370       380       390       400       410 

>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s  (326 aa)
 initn: 740 init1: 472 opt: 903  Z-score: 919.3  bits: 178.4 E(85289): 1.8e-44
Smith-Waterman score: 903; 48.5% identity (74.6% similar) in 307 aa overlap (8-312:10-310)

                 10        20        30        40        50        
pF1KB8   MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL
                : :...:..:: .:: :::::  :: . ..:.  :  :.::::.:::::: 
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB8 FAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT
       ..::.:: :..:  : :. ::..:: ::.::::::..:::.:::::: . .::::: .::
NP_000 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB8 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVP
         ::  .::  :.:.: .::::..:::.  ::..   . : .. . .  ..:: ::.:. 
NP_000 PRRAAVAIAGCWILSFVVGLTPMFGWNNL-SAVE---RAWAANGSMGEPVIKCEFEKVIS
              130       140        150          160       170      

      180       190       200       210         220       230      
pF1KB8 MSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSL
       : ::::::::  ::::::.:..::...: .  .::..  .      .    .:.. ::::
NP_000 MEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSL
        180       190       200       210       220       230      

        240       250       260       270       280       290      
pF1KB8 AMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD
       :.:. .::: :::.: .::.::: :.   .::.    .::.:.:.::..::::::.: . 
NP_000 ALILFLFALSWLPLHILNCITLFCPSC--HKPSILTYIAIFLTHGNSAMNPIVYAFRIQK
        240       250       260         270       280       290    

        300       310       320       330  
pF1KB8 FRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
       :: :: :: . .. ::                    
NP_000 FRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD    
          300       310       320          

>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom  (326 aa)
 initn: 740 init1: 472 opt: 903  Z-score: 919.3  bits: 178.4 E(85289): 1.8e-44
Smith-Waterman score: 903; 48.5% identity (74.6% similar) in 307 aa overlap (8-312:10-310)

                 10        20        30        40        50        
pF1KB8   MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL
                : :...:..:: .:: :::::  :: . ..:.  :  :.::::.:::::: 
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB8 FAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT
       ..::.:: :..:  : :. ::..:: ::.::::::..:::.:::::: . .::::: .::
NP_001 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB8 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVP
         ::  .::  :.:.: .::::..:::.  ::..   . : .. . .  ..:: ::.:. 
NP_001 PRRAAVAIAGCWILSFVVGLTPMFGWNNL-SAVE---RAWAANGSMGEPVIKCEFEKVIS
              130       140        150          160       170      

      180       190       200       210         220       230      
pF1KB8 MSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSL
       : ::::::::  ::::::.:..::...: .  .::..  .      .    .:.. ::::
NP_001 MEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSL
        180       190       200       210       220       230      

        240       250       260       270       280       290      
pF1KB8 AMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD
       :.:. .::: :::.: .::.::: :.   .::.    .::.:.:.::..::::::.: . 
NP_001 ALILFLFALSWLPLHILNCITLFCPSC--HKPSILTYIAIFLTHGNSAMNPIVYAFRIQK
        240       250       260         270       280       290    

        300       310       320       330  
pF1KB8 FRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
       :: :: :: . .. ::                    
NP_001 FRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD    
          300       310       320          




332 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:40:18 2016 done: Fri Nov  4 16:40:19 2016
 Total Scan time:  7.280 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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