Result of FASTA (omim) for pF1KB8951
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8951, 326 aa
  1>>>pF1KB8951 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6767+/-0.000402; mu= 19.1347+/- 0.025
 mean_var=87.5994+/-23.948, 0's: 0 Z-trim(111.5): 526  B-trim: 2128 in 2/48
 Lambda= 0.137033
 statistics sampled from 19329 (20086) to 19329 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.236), width:  16
 Scan time:  7.160

The best scores are:                                      opt bits E(85289)
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 2171 439.7  4e-123
NP_001041695 (OMIM: 102775) adenosine receptor A1  ( 326) 2171 439.7  4e-123
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 1015 211.3 2.9e-54
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332)  903 189.0 1.2e-47
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318)  859 180.3 4.7e-45
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229)  566 122.2   1e-27
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231)  554 119.8 5.4e-27
NP_001289608 (OMIM: 600445) adenosine receptor A3  ( 173)  514 111.8 1.1e-24
NP_001289607 (OMIM: 600445) adenosine receptor A3  ( 123)  377 84.5 1.2e-16
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116)  349 78.9 5.5e-15
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478)  355 80.9   6e-15
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin  ( 528)  355 80.9 6.4e-15
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  346 78.9 1.7e-14
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  346 78.9 1.7e-14
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  346 79.0 1.8e-14
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  346 79.0 1.9e-14
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  346 79.0 1.9e-14
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  346 79.0 1.9e-14
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  346 79.0 1.9e-14
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  346 79.0 1.9e-14
NP_444508 (OMIM: 606927) trace amine-associated re ( 342)  342 78.1 2.9e-14
NP_778237 (OMIM: 608923) trace amine-associated re ( 345)  333 76.3   1e-13
NP_778227 (OMIM: 608282) trace amine-associated re ( 348)  331 76.0 1.3e-13
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  329 75.7   2e-13
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  327 75.3 2.6e-13
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin  ( 405)  322 74.3   5e-13
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489)  322 74.4 5.6e-13
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin  ( 539)  322 74.4   6e-13
NP_848566 (OMIM: 300513) glucose-dependent insulin ( 335)  317 73.2 8.8e-13
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415)  312 72.3   2e-12
NP_612200 (OMIM: 609333) trace amine-associated re ( 339)  309 71.6 2.6e-12
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398)  308 71.5 3.4e-12
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360)  306 71.0 4.2e-12
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378)  306 71.1 4.3e-12
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387)  306 71.1 4.3e-12
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388)  306 71.1 4.4e-12
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic  ( 408)  306 71.1 4.5e-12
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411)  306 71.1 4.5e-12
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428)  306 71.1 4.6e-12
NP_003958 (OMIM: 607405) trace amine-associated re ( 337)  303 70.4   6e-12
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465)  303 70.6 7.4e-12
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308)  294 68.6 1.9e-11
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic  ( 477)  296 69.2   2e-11


>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s  (326 aa)
 initn: 2171 init1: 2171 opt: 2171  Z-score: 2331.5  bits: 439.7 E(85289): 4e-123
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
              250       260       270       280       290       300

              310       320      
pF1KB8 KIWNDHFRCQPAPPIDEDLPEERPDD
       ::::::::::::::::::::::::::
NP_000 KIWNDHFRCQPAPPIDEDLPEERPDD
              310       320      

>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom  (326 aa)
 initn: 2171 init1: 2171 opt: 2171  Z-score: 2331.5  bits: 439.7 E(85289): 4e-123
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
              250       260       270       280       290       300

              310       320      
pF1KB8 KIWNDHFRCQPAPPIDEDLPEERPDD
       ::::::::::::::::::::::::::
NP_001 KIWNDHFRCQPAPPIDEDLPEERPDD
              310       320      

>>XP_005244958 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 1463 init1: 1463 opt: 1463  Z-score: 1576.2  bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)

            90       100       110       120       130       140   
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
                                     ::::::::::::::::::::::::::::::
XP_005 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
          20        30        40        50        60        70     

           150       160       170       180       190       200   
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
          80        90       100       110       120       130     

           210       220       230       240       250       260   
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
         140       150       160       170       180       190     

           270       280       290       300       310       320   
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
         200       210       220       230       240       250     

          
pF1KB8 PDD
       :::
XP_005 PDD
          

>>XP_016855831 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 1463 init1: 1463 opt: 1463  Z-score: 1576.2  bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)

            90       100       110       120       130       140   
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
                                     ::::::::::::::::::::::::::::::
XP_016 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
          20        30        40        50        60        70     

           150       160       170       180       190       200   
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
          80        90       100       110       120       130     

           210       220       230       240       250       260   
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
         140       150       160       170       180       190     

           270       280       290       300       310       320   
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
         200       210       220       230       240       250     

          
pF1KB8 PDD
       :::
XP_016 PDD
          

>>XP_005244959 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 1463 init1: 1463 opt: 1463  Z-score: 1576.2  bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)

            90       100       110       120       130       140   
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
                                     ::::::::::::::::::::::::::::::
XP_005 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
          20        30        40        50        60        70     

           150       160       170       180       190       200   
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
          80        90       100       110       120       130     

           210       220       230       240       250       260   
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
         140       150       160       170       180       190     

           270       280       290       300       310       320   
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
         200       210       220       230       240       250     

          
pF1KB8 PDD
       :::
XP_005 PDD
          

>>NP_001265426 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1007 init1: 700 opt: 1015  Z-score: 1095.2  bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
                ..:: .:. ::.... ::::: ::: .:. :...:  :.::::.::.:::.
NP_001    MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       :.::.:: :. :  .  : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
         ::   :: ::.:::..:::::.:::: .  ...   . . ::  . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
       120       130       140       150       160       170       

              190       200       210        220        230        
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
       ::::::. :: :::::. .::..:   :.::..  :    :.  ..   ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
       180       190       200       210       220       230       

      240       250       260        270       280       290       
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       :. :::: ::::::.::.:.:::.: : :  : :.:: :.: ::..::..::.::..:: 
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
       240       250       260       270       280       290       

       300       310       320                                     
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD                               
       :: ::  .:   :  :                                            
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
       300       310       320       330       340       350       

>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1007 init1: 700 opt: 1015  Z-score: 1095.2  bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
                ..:: .:. ::.... ::::: ::: .:. :...:  :.::::.::.:::.
NP_001    MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       :.::.:: :. :  .  : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
         ::   :: ::.:::..:::::.:::: .  ...   . . ::  . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
       120       130       140       150       160       170       

              190       200       210        220        230        
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
       ::::::. :: :::::. .::..:   :.::..  :    :.  ..   ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
       180       190       200       210       220       230       

      240       250       260        270       280       290       
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       :. :::: ::::::.::.:.:::.: : :  : :.:: :.: ::..::..::.::..:: 
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
       240       250       260       270       280       290       

       300       310       320                                     
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD                               
       :: ::  .:   :  :                                            
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
       300       310       320       330       340       350       

>>NP_000666 (OMIM: 102776) adenosine receptor A2a [Homo   (412 aa)
 initn: 1007 init1: 700 opt: 1015  Z-score: 1095.2  bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
                ..:: .:. ::.... ::::: ::: .:. :...:  :.::::.::.:::.
NP_000    MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       :.::.:: :. :  .  : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_000 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
         ::   :: ::.:::..:::::.:::: .  ...   . . ::  . : :: :. :.::
NP_000 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
       120       130       140       150       160       170       

              190       200       210        220        230        
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
       ::::::. :: :::::. .::..:   :.::..  :    :.  ..   ::.. :::::.
NP_000 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
       180       190       200       210       220       230       

      240       250       260        270       280       290       
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       :. :::: ::::::.::.:.:::.: : :  : :.:: :.: ::..::..::.::..:: 
NP_000 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
       240       250       260       270       280       290       

       300       310       320                                     
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD                               
       :: ::  .:   :  :                                            
NP_000 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
       300       310       320       330       340       350       

>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1007 init1: 700 opt: 1015  Z-score: 1095.2  bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
                ..:: .:. ::.... ::::: ::: .:. :...:  :.::::.::.:::.
NP_001    MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       :.::.:: :. :  .  : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
         ::   :: ::.:::..:::::.:::: .  ...   . . ::  . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
       120       130       140       150       160       170       

              190       200       210        220        230        
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
       ::::::. :: :::::. .::..:   :.::..  :    :.  ..   ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
       180       190       200       210       220       230       

      240       250       260        270       280       290       
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       :. :::: ::::::.::.:.:::.: : :  : :.:: :.: ::..::..::.::..:: 
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
       240       250       260       270       280       290       

       300       310       320                                     
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD                               
       :: ::  .:   :  :                                            
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
       300       310       320       330       340       350       

>>NP_001265428 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 1007 init1: 700 opt: 1015  Z-score: 1095.2  bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)

               10        20        30        40        50        60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
                ..:: .:. ::.... ::::: ::: .:. :...:  :.::::.::.:::.
NP_001    MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
       :.::.:: :. :  .  : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
         ::   :: ::.:::..:::::.:::: .  ...   . . ::  . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
       120       130       140       150       160       170       

              190       200       210        220        230        
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
       ::::::. :: :::::. .::..:   :.::..  :    :.  ..   ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
       180       190       200       210       220       230       

      240       250       260        270       280       290       
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       :. :::: ::::::.::.:.:::.: : :  : :.:: :.: ::..::..::.::..:: 
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
       240       250       260       270       280       290       

       300       310       320                                     
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD                               
       :: ::  .:   :  :                                            
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
       300       310       320       330       340       350       




326 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:38:35 2016 done: Fri Nov  4 16:38:36 2016
 Total Scan time:  7.160 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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