Result of FASTA (omim) for pF1KB8746
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8746, 177 aa
  1>>>pF1KB8746 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2141+/-0.00028; mu= 13.9815+/- 0.017
 mean_var=86.1702+/-18.317, 0's: 0 Z-trim(120.4): 180  B-trim: 1364 in 1/49
 Lambda= 0.138164
 statistics sampled from 35360 (35615) to 35360 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.418), width:  16
 Scan time:  5.900

The best scores are:                                      opt bits E(85289)
NP_000165 (OMIM: 173515,231200) platelet glycoprot ( 177) 1252 258.4 4.3e-69
XP_011511004 (OMIM: 173515,231200) PREDICTED: plat ( 177) 1252 258.4 4.3e-69
XP_011511003 (OMIM: 173515,231200) PREDICTED: plat ( 177) 1252 258.4 4.3e-69
XP_005247431 (OMIM: 173515,231200) PREDICTED: plat ( 177) 1252 258.4 4.3e-69
NP_000398 (OMIM: 138720,231200) platelet glycoprot ( 206)  333 75.3 6.7e-14
XP_011520834 (OMIM: 173900,601313) PREDICTED: poly (4287)  219 53.8 4.1e-06
NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545)  199 49.0 1.5e-05
XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545)  199 49.0 1.5e-05
NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545)  199 49.0 1.5e-05
XP_016877935 (OMIM: 614179) PREDICTED: immunoglobu ( 468)  186 46.3   8e-05
NP_001123609 (OMIM: 614179) immunoglobulin superfa ( 745)  186 46.5 0.00011
NP_065902 (OMIM: 614179) immunoglobulin superfamil ( 745)  186 46.5 0.00011
XP_011520142 (OMIM: 614179) PREDICTED: immunoglobu ( 745)  186 46.5 0.00011
NP_001123608 (OMIM: 614179) immunoglobulin superfa ( 745)  186 46.5 0.00011
XP_011520143 (OMIM: 614179) PREDICTED: immunoglobu ( 745)  186 46.5 0.00011
NP_001123610 (OMIM: 614179) immunoglobulin superfa ( 745)  186 46.5 0.00011
NP_001010847 (OMIM: 615212) leucine-rich repeat-co ( 294)  175 43.9 0.00026
NP_001013675 (OMIM: 613505) leucine-rich repeat-co ( 334)  172 43.4 0.00043
NP_001258 (OMIM: 602178) chondroadherin precursor  ( 359)  170 43.0  0.0006
XP_011522516 (OMIM: 602178) PREDICTED: chondroadhe ( 440)  170 43.1  0.0007
NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660)  171 43.5 0.00081
XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660)  171 43.5 0.00081
XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660)  171 43.5 0.00081
XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660)  171 43.5 0.00081
NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660)  171 43.5 0.00081
XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  171 43.5 0.00081
NP_003052 (OMIM: 603742) slit homolog 1 protein pr (1534)  175 44.6 0.00086
NP_848665 (OMIM: 610462) reticulon-4 receptor-like ( 420)  168 42.7 0.00089
NP_055632 (OMIM: 613356) TLR4 interactor with leuc ( 811)  171 43.6 0.00094
XP_011512212 (OMIM: 603746) PREDICTED: slit homolo (1159)  172 43.9  0.0011
NP_001005210 (OMIM: 615213) leucine-rich repeat-co ( 341)  165 42.0  0.0012
XP_005273528 (OMIM: 606823) PREDICTED: adhesion G  ( 813)  169 43.2  0.0012
NP_037412 (OMIM: 604806) leucine-rich repeat trans ( 674)  168 42.9  0.0013
XP_005273918 (OMIM: 604806) PREDICTED: leucine-ric ( 674)  168 42.9  0.0013
XP_011543185 (OMIM: 604806) PREDICTED: leucine-ric ( 674)  168 42.9  0.0013
NP_958934 (OMIM: 602059) immunoglobulin superfamil ( 428)  165 42.1  0.0014
NP_005536 (OMIM: 602059) immunoglobulin superfamil ( 428)  165 42.1  0.0014
NP_001137480 (OMIM: 300561) SLIT and NTRK-like pro ( 845)  167 42.8  0.0017
NP_001137477 (OMIM: 300561) SLIT and NTRK-like pro ( 845)  167 42.8  0.0017
NP_001137475 (OMIM: 300561) SLIT and NTRK-like pro ( 845)  167 42.8  0.0017
XP_005262401 (OMIM: 300561) PREDICTED: SLIT and NT ( 845)  167 42.8  0.0017
NP_001137482 (OMIM: 300561) SLIT and NTRK-like pro ( 845)  167 42.8  0.0017


>>NP_000165 (OMIM: 173515,231200) platelet glycoprotein   (177 aa)
 initn: 1252 init1: 1252 opt: 1252  Z-score: 1361.4  bits: 258.4 E(85289): 4.3e-69
Smith-Waterman score: 1252; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)

               10        20        30        40        50        60
pF1KB8 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
               70        80        90       100       110       120

              130       140       150       160       170       
pF1KB8 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
              130       140       150       160       170       

>>XP_011511004 (OMIM: 173515,231200) PREDICTED: platelet  (177 aa)
 initn: 1252 init1: 1252 opt: 1252  Z-score: 1361.4  bits: 258.4 E(85289): 4.3e-69
Smith-Waterman score: 1252; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)

               10        20        30        40        50        60
pF1KB8 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
               70        80        90       100       110       120

              130       140       150       160       170       
pF1KB8 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
              130       140       150       160       170       

>>XP_011511003 (OMIM: 173515,231200) PREDICTED: platelet  (177 aa)
 initn: 1252 init1: 1252 opt: 1252  Z-score: 1361.4  bits: 258.4 E(85289): 4.3e-69
Smith-Waterman score: 1252; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)

               10        20        30        40        50        60
pF1KB8 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
               70        80        90       100       110       120

              130       140       150       160       170       
pF1KB8 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
              130       140       150       160       170       

>>XP_005247431 (OMIM: 173515,231200) PREDICTED: platelet  (177 aa)
 initn: 1252 init1: 1252 opt: 1252  Z-score: 1361.4  bits: 258.4 E(85289): 4.3e-69
Smith-Waterman score: 1252; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)

               10        20        30        40        50        60
pF1KB8 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
               70        80        90       100       110       120

              130       140       150       160       170       
pF1KB8 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
              130       140       150       160       170       

>>NP_000398 (OMIM: 138720,231200) platelet glycoprotein   (206 aa)
 initn: 264 init1: 158 opt: 333  Z-score: 370.5  bits: 75.3 E(85289): 6.7e-14
Smith-Waterman score: 333; 39.3% identity (60.7% similar) in 168 aa overlap (7-169:13-167)

                     10        20        30        40           50 
pF1KB8       MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLT--ALP-ALPA
                   :.::   .. .  ::.::.:      :  :::  .:::  .:: :.:.
NP_000 MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSC-----AGTLVDCGRRGLTWASLPTAFPV
               10        20        30             40        50     

              60        70        80        90       100       110 
pF1KB8 RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQ-
        : .:.:..:.: ..::: .: :: :.:  .  :::.::: :. :: ::  :  .:  . 
NP_000 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD
          60        70        80        90       100       110     

              120       130       140        150       160         
pF1KB8 VRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVL-WDVALVAVAALGLALLAGLL
       .::..:        :::  :   .   .:.:.   :: : : .  . .: :::.:: .::
NP_000 LRCVAPPALR----GRLLPYLAED---ELRAA-CAPGPLCWGALAAQLALLGLGLLHALL
         120           130          140        150       160       

     170                                      
pF1KB8 CATTEALD                               
                                              
NP_000 LVLLLCRLRRLRARARARAAARLSLTDPLVAERAGTDES
       170       180       190       200      

>>XP_011520834 (OMIM: 173900,601313) PREDICTED: polycyst  (4287 aa)
 initn: 159 init1: 112 opt: 219  Z-score: 230.7  bits: 53.8 E(85289): 4.1e-06
Smith-Waterman score: 220; 32.1% identity (50.8% similar) in 187 aa overlap (2-171:6-187)

                      10              20        30        40       
pF1KB8     MPAWGALFL---LWATAEA------TKDCPSPCTCRALETMGLWVDCRGHGLTAL-
            ::  :: :   ::  : :         :  :: :      .  :.: :.:: .: 
XP_011 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
               10        20        30        40        50        60

           50        60        70        80        90       100    
pF1KB8 PAL--PARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRT
       :::  :: .  : ...: :...  : . .:  :  :... ::..:::.:..:  : :.. 
XP_011 PALRIPADATALDVSHNLLRALDVGLLANLSALAELNLSGNPFECDCGLAWLPRWAEEQQ
               70        80        90       100       110       120

               110       120       130       140       150         
pF1KB8 -----PEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAA
            :::   . ::.:.  :  ::  .   . : :: .  :  .  .    :: :. .:
XP_011 VRVVQPEA---ATCAGPGSLAGQPLLGIPLLDSG-CGEEYVAC-LPDNSSGTVAAVSFSA
                 130       140       150         160       170     

     160       170                                                 
pF1KB8 LGLALLAGLLCATTEALD                                          
          .::    :.                                                
XP_011 AHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPTC
         180       190       200       210       220       230     

>>NP_001073982 (OMIM: 603104) carboxypeptidase N subunit  (545 aa)
 initn: 238 init1: 113 opt: 199  Z-score: 220.7  bits: 49.0 E(85289): 1.5e-05
Smith-Waterman score: 199; 34.8% identity (57.6% similar) in 132 aa overlap (41-159:347-477)

               20        30        40         50           60      
pF1KB8 WATAEATKDCPSPCTCRALETMGLWVDCRGHGLTAL-PALP---ARTRHLLLANNSLQSV
                                     ..:::: :::    .. . : :..:.: ..
NP_001 SLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTL
        320       330       340       350       360       370      

         70        80        90       100        110       120     
pF1KB8 PPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEAL-LQVRCASPSLAAHGPLG
       : : ::   .: .: .  :::.::: :.::  ::.. : . : .:. ::.:.      . 
NP_001 PEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQVVP
        380       390       400       410       420       430      

         130            140          150       160       170       
pF1KB8 RLTGYQLGSCGWQ-----LQASW---VRPGVLWDVALVAVAALGLALLAGLLCATTEALD
        :.  ::  :        .:..:    . :  ::.:.   ::                  
NP_001 ALNEKQL-VCPVTRDHLGFQVTWPDESKAGGSWDLAVQERAARSQCTYSNPEGTVVLACD
        440        450       460       470       480       490     

NP_001 QAQCRWLNVQLSPQQGSLGLQYNASQEWDLRSSCGSLRLTVSIEARAAGP
         500       510       520       530       540     

>>XP_005269337 (OMIM: 603104) PREDICTED: carboxypeptidas  (545 aa)
 initn: 238 init1: 113 opt: 199  Z-score: 220.7  bits: 49.0 E(85289): 1.5e-05
Smith-Waterman score: 199; 34.8% identity (57.6% similar) in 132 aa overlap (41-159:347-477)

               20        30        40         50           60      
pF1KB8 WATAEATKDCPSPCTCRALETMGLWVDCRGHGLTAL-PALP---ARTRHLLLANNSLQSV
                                     ..:::: :::    .. . : :..:.: ..
XP_005 SLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTL
        320       330       340       350       360       370      

         70        80        90       100        110       120     
pF1KB8 PPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEAL-LQVRCASPSLAAHGPLG
       : : ::   .: .: .  :::.::: :.::  ::.. : . : .:. ::.:.      . 
XP_005 PEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQVVP
        380       390       400       410       420       430      

         130            140          150       160       170       
pF1KB8 RLTGYQLGSCGWQ-----LQASW---VRPGVLWDVALVAVAALGLALLAGLLCATTEALD
        :.  ::  :        .:..:    . :  ::.:.   ::                  
XP_005 ALNEKQL-VCPVTRDHLGFQVTWPDESKAGGSWDLAVQERAARSQCTYSNPEGTVVLACD
        440        450       460       470       480       490     

XP_005 QAQCRWLNVQLSPQQGSLGLQYNASQEWDLRSSCGSLRLTVSIEARAAGP
         500       510       520       530       540     

>>NP_001278917 (OMIM: 603104) carboxypeptidase N subunit  (545 aa)
 initn: 238 init1: 113 opt: 199  Z-score: 220.7  bits: 49.0 E(85289): 1.5e-05
Smith-Waterman score: 199; 34.8% identity (57.6% similar) in 132 aa overlap (41-159:347-477)

               20        30        40         50           60      
pF1KB8 WATAEATKDCPSPCTCRALETMGLWVDCRGHGLTAL-PALP---ARTRHLLLANNSLQSV
                                     ..:::: :::    .. . : :..:.: ..
NP_001 SLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTL
        320       330       340       350       360       370      

         70        80        90       100        110       120     
pF1KB8 PPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEAL-LQVRCASPSLAAHGPLG
       : : ::   .: .: .  :::.::: :.::  ::.. : . : .:. ::.:.      . 
NP_001 PEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQVVP
        380       390       400       410       420       430      

         130            140          150       160       170       
pF1KB8 RLTGYQLGSCGWQ-----LQASW---VRPGVLWDVALVAVAALGLALLAGLLCATTEALD
        :.  ::  :        .:..:    . :  ::.:.   ::                  
NP_001 ALNEKQL-VCPVTRDHLGFQVTWPDESKAGGSWDLAVQERAARSQCTYSNPEGTVVLACD
        440        450       460       470       480       490     

NP_001 QAQCRWLNVQLSPQQGSLGLQYNASQEWDLRSSCGSLRLTVSIEARAAGP
         500       510       520       530       540     

>>XP_016877935 (OMIM: 614179) PREDICTED: immunoglobulin   (468 aa)
 initn: 285 init1: 143 opt: 186  Z-score: 207.6  bits: 46.3 E(85289): 8e-05
Smith-Waterman score: 186; 39.5% identity (60.5% similar) in 86 aa overlap (45-127:142-225)

           20        30        40        50        60        70    
pF1KB8 EATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGAFDHL
                                     :: :::   : : . :: :... ::.:: :
XP_016 SSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPD-LRSLRINNNRLRTLAPGTFDAL
             120       130       140        150       160       170

           80        90       100          110       120       130 
pF1KB8 PQLQTLDVTQNPWHCDCSLTYLRLWLEDRT---PEALLQVRCASPSLAAHGPLGRLTGYQ
         :. :.. .::.:: :.:..:. :  .     ::   .. ::::      :. ::    
XP_016 SALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPD-SIACASPPALQGVPVYRLPALP
              180       190       200        210       220         

             140       150       160       170                     
pF1KB8 LGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD              
                                                                   
XP_016 CAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLS
     230       240       250       260       270       280         




177 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 15:11:07 2016 done: Fri Nov  4 15:11:08 2016
 Total Scan time:  5.900 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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