Result of FASTA (omim) for pF1KB8681
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8681, 377 aa
  1>>>pF1KB8681 377 - 377 aa - 377 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5040+/-0.00036; mu= 17.0147+/- 0.022
 mean_var=81.8587+/-16.651, 0's: 0 Z-trim(115.8): 28  B-trim: 603 in 1/50
 Lambda= 0.141756
 statistics sampled from 26439 (26464) to 26439 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.31), width:  16
 Scan time:  8.800

The best scores are:                                      opt bits E(85289)
NP_079348 (OMIM: 608152) prostaglandin E synthase  ( 377) 2522 525.3 9.2e-149
NP_945176 (OMIM: 608152) prostaglandin E synthase  ( 186) 1256 266.1 4.6e-71
NP_001243264 (OMIM: 608152) prostaglandin E syntha ( 186) 1256 266.1 4.6e-71
XP_011517353 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71
XP_005252296 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71
XP_011517352 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71


>>NP_079348 (OMIM: 608152) prostaglandin E synthase 2 is  (377 aa)
 initn: 2522 init1: 2522 opt: 2522  Z-score: 2791.7  bits: 525.3 E(85289): 9.2e-149
Smith-Waterman score: 2522; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377)

               10        20        30        40        50        60
pF1KB8 MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 WLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ
              310       320       330       340       350       360

              370       
pF1KB8 PWYLRVERAITEASPAH
       :::::::::::::::::
NP_079 PWYLRVERAITEASPAH
              370       

>>NP_945176 (OMIM: 608152) prostaglandin E synthase 2 is  (186 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1396.7  bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)

             170       180       190       200       210       220 
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                     ::::::::::::::::::::::::::::::
NP_945                               MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                             10        20        30

             230       240       250       260       270       280 
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
               40        50        60        70        80        90

             290       300       310       320       330       340 
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
              100       110       120       130       140       150

             350       360       370       
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
       ::::::::::::::::::::::::::::::::::::
NP_945 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
              160       170       180      

>>NP_001243264 (OMIM: 608152) prostaglandin E synthase 2  (186 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1396.7  bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)

             170       180       190       200       210       220 
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                     ::::::::::::::::::::::::::::::
NP_001                               MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                             10        20        30

             230       240       250       260       270       280 
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
               40        50        60        70        80        90

             290       300       310       320       330       340 
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
              100       110       120       130       140       150

             350       360       370       
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
       ::::::::::::::::::::::::::::::::::::
NP_001 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
              160       170       180      

>>XP_011517353 (OMIM: 608152) PREDICTED: prostaglandin E  (186 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1396.7  bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)

             170       180       190       200       210       220 
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                     ::::::::::::::::::::::::::::::
XP_011                               MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                             10        20        30

             230       240       250       260       270       280 
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
               40        50        60        70        80        90

             290       300       310       320       330       340 
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
              100       110       120       130       140       150

             350       360       370       
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
       ::::::::::::::::::::::::::::::::::::
XP_011 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
              160       170       180      

>>XP_005252296 (OMIM: 608152) PREDICTED: prostaglandin E  (186 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1396.7  bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)

             170       180       190       200       210       220 
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                     ::::::::::::::::::::::::::::::
XP_005                               MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                             10        20        30

             230       240       250       260       270       280 
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
               40        50        60        70        80        90

             290       300       310       320       330       340 
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
              100       110       120       130       140       150

             350       360       370       
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
       ::::::::::::::::::::::::::::::::::::
XP_005 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
              160       170       180      

>>XP_011517352 (OMIM: 608152) PREDICTED: prostaglandin E  (186 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1396.7  bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)

             170       180       190       200       210       220 
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                     ::::::::::::::::::::::::::::::
XP_011                               MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
                                             10        20        30

             230       240       250       260       270       280 
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
               40        50        60        70        80        90

             290       300       310       320       330       340 
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
              100       110       120       130       140       150

             350       360       370       
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
       ::::::::::::::::::::::::::::::::::::
XP_011 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
              160       170       180      




377 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:31:54 2016 done: Fri Nov  4 14:31:55 2016
 Total Scan time:  8.800 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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