Result of FASTA (omim) for pF1KB8677
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8677, 368 aa
  1>>>pF1KB8677 368 - 368 aa - 368 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9829+/-0.000348; mu= 18.2699+/- 0.022
 mean_var=63.1004+/-12.780, 0's: 0 Z-trim(114.2): 15  B-trim: 59 in 1/50
 Lambda= 0.161458
 statistics sampled from 23863 (23876) to 23863 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.28), width:  16
 Scan time:  8.320

The best scores are:                                      opt bits E(85289)
NP_056399 (OMIM: 611519) polymerase delta-interact ( 368) 2540 600.3 2.3e-171
NP_001277074 (OMIM: 611519) polymerase delta-inter ( 350) 1864 442.8 5.6e-124
XP_016873022 (OMIM: 609089) PREDICTED: F-box only  ( 309)  197 54.4   4e-07
XP_011518284 (OMIM: 609089) PREDICTED: F-box only  ( 317)  197 54.4   4e-07
NP_208385 (OMIM: 609089) F-box only protein 3 isof ( 415)  197 54.5   5e-07
XP_011518283 (OMIM: 609089) PREDICTED: F-box only  ( 415)  197 54.5   5e-07
NP_036307 (OMIM: 609089) F-box only protein 3 isof ( 471)  197 54.6 5.6e-07
XP_011518282 (OMIM: 609089) PREDICTED: F-box only  ( 479)  197 54.6 5.6e-07


>>NP_056399 (OMIM: 611519) polymerase delta-interacting   (368 aa)
 initn: 2540 init1: 2540 opt: 2540  Z-score: 3197.4  bits: 600.3 E(85289): 2.3e-171
Smith-Waterman score: 2540; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368)

               10        20        30        40        50        60
pF1KB8 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
              310       320       330       340       350       360

               
pF1KB8 TPPSGLHW
       ::::::::
NP_056 TPPSGLHW
               

>>NP_001277074 (OMIM: 611519) polymerase delta-interacti  (350 aa)
 initn: 1864 init1: 1864 opt: 1864  Z-score: 2346.7  bits: 442.8 E(85289): 5.6e-124
Smith-Waterman score: 2362; 95.1% identity (95.1% similar) in 368 aa overlap (1-368:1-350)

               10        20        30        40        50        60
pF1KB8 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
       :::::::::::::::::::::                  :::::::::::::::::::::
NP_001 VLETVGVFEVPKQNGKYETGQ------------------ARLYDRDVASAAPEKAENPAG
               70        80                          90       100  

              130       140       150       160       170       180
pF1KB8 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KB8 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KB8 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KB8 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
            290       300       310       320       330       340  

               
pF1KB8 TPPSGLHW
       ::::::::
NP_001 TPPSGLHW
            350

>>XP_016873022 (OMIM: 609089) PREDICTED: F-box only prot  (309 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 249.0  bits: 54.4 E(85289): 4e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:118-239)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
XP_016 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
        90       100       110       120       130       140       

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
XP_016 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
       150       160       170       180       190        200      

            330         340       350       360                    
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW            
       ....::.: :  ::.:     . :.: :: : .                           
XP_016 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEE
        210       220       230       240       250       260      

XP_016 EEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
        270       280       290       300         

>>XP_011518284 (OMIM: 609089) PREDICTED: F-box only prot  (317 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 248.8  bits: 54.4 E(85289): 4e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:118-239)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
        90       100       110       120       130       140       

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
       150       160       170       180       190        200      

            330         340       350       360                    
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW            
       ....::.: :  ::.:     . :.: :: : .                           
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLPRVLSFSPGTCVFDT
        210       220       230       240       250       260      

XP_011 LSHHVRSPATMKPSCRRDHVETSHRDRGRHPGAPAVSDSRYLDHPARVPDM
        270       280       290       300       310       

>>NP_208385 (OMIM: 609089) F-box only protein 3 isoform   (415 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 247.1  bits: 54.5 E(85289): 5e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
NP_208 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
     250       260       270       280       290       300         

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
NP_208 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
     310       320       330       340       350        360        

            330         340       350       360        
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
       ....::.: :  ::.:     . :.: :: : .               
NP_208 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLVS 
      370       380       390       400       410      

>>XP_011518283 (OMIM: 609089) PREDICTED: F-box only prot  (415 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 247.1  bits: 54.5 E(85289): 5e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
     250       260       270       280       290       300         

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
     310       320       330       340       350        360        

            330         340       350       360        
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
       ....::.: :  ::.:     . :.: :: : .               
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLFW 
      370       380       390       400       410      

>>NP_036307 (OMIM: 609089) F-box only protein 3 isoform   (471 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 246.3  bits: 54.6 E(85289): 5.6e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
NP_036 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
     250       260       270       280       290       300         

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
NP_036 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
     310       320       330       340       350        360        

            330         340       350       360                    
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW            
       ....::.: :  ::.:     . :.: :: : .                           
NP_036 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEE
      370       380       390       400       410       420        

NP_036 EEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
      430       440       450       460       470 

>>XP_011518282 (OMIM: 609089) PREDICTED: F-box only prot  (479 aa)
 initn: 110 init1: 110 opt: 197  Z-score: 246.2  bits: 54.6 E(85289): 5.6e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)

        210       220       230       240       250       260      
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
                                     :: .: :.:   ..    . .   :.. : 
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
     250       260       270       280       290       300         

        270           280       290       300       310       320  
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
       ::.:     :   . ::  :.::: . .: .: :.: ::::. :..:  . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
     310       320       330       340       350        360        

            330         340       350       360                    
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW            
       ....::.: :  ::.:     . :.: :: : .                           
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLPRVLSFSPGTCVFDT
      370       380       390       400       410       420        

XP_011 LSHHVRSPATMKPSCRRDHVETSHRDRGRHPGAPAVSDSRYLDHPARVPDM
      430       440       450       460       470         




368 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:30:07 2016 done: Fri Nov  4 14:30:09 2016
 Total Scan time:  8.320 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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