Result of FASTA (omim) for pF1KB8658
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8658, 520 aa
  1>>>pF1KB8658 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.7681+/-0.000452; mu= -12.6302+/- 0.029
 mean_var=572.8652+/-118.155, 0's: 0 Z-trim(124.8): 74  B-trim: 895 in 1/60
 Lambda= 0.053586
 statistics sampled from 47140 (47221) to 47140 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.554), width:  16
 Scan time: 11.180

The best scores are:                                      opt bits E(85289)
NP_001128410 (OMIM: 607686) pre-mRNA 3'-end-proces ( 520) 3565 290.1 1.1e-77
XP_005265839 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 535) 3380 275.8 2.2e-73
XP_016864158 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 529) 2496 207.5 8.1e-53
XP_005265838 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 544) 2311 193.2 1.7e-48
XP_016864154 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 558) 2292 191.8 4.7e-48
XP_016864157 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 543) 2290 191.6 5.1e-48
XP_016864160 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 499) 2044 172.5 2.6e-42
XP_016864151 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 579) 2022 170.9 9.2e-42
NP_112179 (OMIM: 607686) pre-mRNA 3'-end-processin ( 594) 2022 170.9 9.4e-42
XP_016864155 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 556) 2016 170.4 1.2e-41
XP_005265831 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 571) 2016 170.4 1.3e-41
XP_016864153 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 565) 1644 141.7 5.7e-33
XP_016864156 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 552) 1548 134.2 9.6e-31
XP_016864152 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 567) 1548 134.2 9.7e-31
XP_005265830 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 580) 1548 134.3 9.9e-31
NP_001128409 (OMIM: 607686) pre-mRNA 3'-end-proces ( 588) 1548 134.3   1e-30
XP_005265826 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 603) 1548 134.3   1e-30
XP_016864159 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 526) 1407 123.3 1.8e-27
XP_005265836 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 549) 1140 102.7   3e-21
XP_005265835 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 558) 1140 102.7   3e-21


>>NP_001128410 (OMIM: 607686) pre-mRNA 3'-end-processing  (520 aa)
 initn: 3565 init1: 3565 opt: 3565  Z-score: 1516.0  bits: 290.1 E(85289): 1.1e-77
Smith-Waterman score: 3565; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)

               10        20        30        40        50        60
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES
              430       440       450       460       470       480

              490       500       510       520
pF1KB8 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
       ::::::::::::::::::::::::::::::::::::::::
NP_001 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
              490       500       510       520

>>XP_005265839 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (535 aa)
 initn: 3380 init1: 3380 opt: 3380  Z-score: 1438.6  bits: 275.8 E(85289): 2.2e-73
Smith-Waterman score: 3525; 97.2% identity (97.2% similar) in 535 aa overlap (1-520:1-535)

               10        20                       30        40     
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP
       ::::::::::::::::::::::::::::               :::::::::::::::::
XP_005 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSR
              310       320       330       340       350       360

         350       360       370       380       390       400     
pF1KB8 SARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRER
              370       380       390       400       410       420

         410       420       430       440       450       460     
pF1KB8 ERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEET
              430       440       450       460       470       480

         470       480       490       500       510       520
pF1KB8 RHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
              490       500       510       520       530     

>>XP_016864158 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (529 aa)
 initn: 3246 init1: 2168 opt: 2496  Z-score: 1069.3  bits: 207.5 E(85289): 8.1e-53
Smith-Waterman score: 3537; 98.3% identity (98.3% similar) in 529 aa overlap (1-520:1-529)

               10        20        30        40        50        60
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF
              250       260       270       280       290       300

              310                320       330       340       350 
pF1KB8 LPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIESGHSSGYDSRSARAFP
       ::::::::::::::::::         :::::::::::::::::::::::::::::::::
XP_016 LPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFP
              310       320       330       340       350       360

             360       370       380       390       400       410 
pF1KB8 YGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRER
              370       380       390       400       410       420

             420       430       440       450       460       470 
pF1KB8 ERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSR
              430       440       450       460       470       480

             480       490       500       510       520
pF1KB8 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
              490       500       510       520         

>>XP_005265838 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (544 aa)
 initn: 3061 init1: 1983 opt: 2311  Z-score: 991.8  bits: 193.2 E(85289): 1.7e-48
Smith-Waterman score: 3497; 95.6% identity (95.6% similar) in 544 aa overlap (1-520:1-544)

               10        20                       30        40     
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP
       ::::::::::::::::::::::::::::               :::::::::::::::::
XP_005 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
              250       260       270       280       290       300

         290       300       310                320       330      
pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIES
       :::::::::::::::::::::::::::::::::         ::::::::::::::::::
XP_005 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIES
              310       320       330       340       350       360

        340       350       360       370       380       390      
pF1KB8 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE
              370       380       390       400       410       420

        400       410       420       430       440       450      
pF1KB8 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE
              430       440       450       460       470       480

        460       470       480       490       500       510      
pF1KB8 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA
              490       500       510       520       530       540

        520
pF1KB8 TPAE
       ::::
XP_005 TPAE
           

>>XP_016864154 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (558 aa)
 initn: 2417 init1: 2245 opt: 2292  Z-score: 983.8  bits: 191.8 E(85289): 4.7e-48
Smith-Waterman score: 3433; 93.1% identity (93.1% similar) in 552 aa overlap (7-520:7-558)

               10        20                       30        40     
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP
             ::::::::::::::::::::::               :::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
              130       140       150       160       170       180

         170       180       190                              200  
pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT-----------------------VQQGR
       ::::::::::::::::::::::::::::::::                       :::::
XP_016 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR
              190       200       210       220       230       240

            210       220       230       240       250       260  
pF1KB8 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENS
              250       260       270       280       290       300

            270       280       290       300       310       320  
pF1KB8 NIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPP
              310       320       330       340       350       360

            330       340       350       360       370       380  
pF1KB8 PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYAR
              370       380       390       400       410       420

            390       400       410       420       430       440  
pF1KB8 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE
              430       440       450       460       470       480

            450       460       470       480       490       500  
pF1KB8 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE
              490       500       510       520       530       540

            510       520
pF1KB8 AGSEPAPEQESTEATPAE
       ::::::::::::::::::
XP_016 AGSEPAPEQESTEATPAE
              550        

>>XP_016864157 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (543 aa)
 initn: 2245 init1: 2245 opt: 2290  Z-score: 983.1  bits: 191.6 E(85289): 5.1e-48
Smith-Waterman score: 3509; 95.8% identity (95.8% similar) in 543 aa overlap (1-520:1-543)

               10        20        30        40        50        60
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
              130       140       150       160       170       180

              190                              200       210       
pF1KB8 RMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKA
       :::::::::::::::::                       ::::::::::::::::::::
XP_016 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA
              190       200       210       220       230       240

       220       230       240       250       260       270       
pF1KB8 EFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KB8 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESG
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KB8 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER
              370       380       390       400       410       420

       400       410       420       430       440       450       
pF1KB8 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER
              430       440       450       460       470       480

       460       470       480       490       500       510       
pF1KB8 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT
              490       500       510       520       530       540

       520
pF1KB8 PAE
       :::
XP_016 PAE
          

>>XP_016864160 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (499 aa)
 initn: 2352 init1: 1983 opt: 2044  Z-score: 880.7  bits: 172.5 E(85289): 2.6e-42
Smith-Waterman score: 2362; 85.1% identity (89.6% similar) in 424 aa overlap (1-400:1-419)

               10        20                       30        40     
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP
       ::::::::::::::::::::::::::::               :::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF
              250       260       270       280       290       300

         290       300       310                320       330      
pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIES
       :::::::::::::::::::::::::::::::::         ::::::::::::::::::
XP_016 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIES
              310       320       330       340       350       360

        340       350       360       370       380       390      
pF1KB8 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE
       :::::::::::::::::: :. .   ..     ......: .   ....: ... :  :.
XP_016 GHSSGYDSRSARAFPYGN-AMKNDTDTGNMQKEVMSVTEQVE---KKKNDIEKD-DTGRK
              370        380       390       400          410      

        400       410       420       430       440       450      
pF1KB8 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE
       :  :                                                        
XP_016 RKPDISLLEVIVDVAMKVKKEIVTGDTNTKNLKEAKKEKKRAVSLPLNRRAPKLHLQNRH
         420       430       440       450       460       470     

>>XP_016864151 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (579 aa)
 initn: 3325 init1: 2014 opt: 2022  Z-score: 870.8  bits: 170.9 E(85289): 9.2e-42
Smith-Waterman score: 3250; 89.3% identity (89.3% similar) in 552 aa overlap (28-520:28-579)

               10        20        30        40        50        60
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
                                  :::::::::::::::::::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
              130       140       150       160       170       180

              190                              200       210       
pF1KB8 RMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKA
       :::::::::::::::::                       ::::::::::::::::::::
XP_016 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA
              190       200       210       220       230       240

       220       230                                           240 
pF1KB8 EFTSPPSLFKTGLPPSR------------------------------------RLPGAID
       :::::::::::::::::                                    :::::::
XP_016 EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID
              250       260       270       280       290       300

             250       260       270       280       290       300 
pF1KB8 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL
              310       320       330       340       350       360

             310       320       330       340       350       360 
pF1KB8 PPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLP
              370       380       390       400       410       420

             370       380       390       400       410       420 
pF1KB8 GSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTP
              430       440       450       460       470       480

             430       440       450       460       470       480 
pF1KB8 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE
              490       500       510       520       530       540

             490       500       510       520
pF1KB8 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
       :::::::::::::::::::::::::::::::::::::::
XP_016 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
              550       560       570         

>>NP_112179 (OMIM: 607686) pre-mRNA 3'-end-processing fa  (594 aa)
 initn: 3140 init1: 2014 opt: 2022  Z-score: 870.6  bits: 170.9 E(85289): 9.4e-42
Smith-Waterman score: 3242; 89.3% identity (89.3% similar) in 551 aa overlap (29-520:44-594)

                 10        20        30        40        50        
pF1KB8   MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGV
                                     ::::::::::::::::::::::::::::::
NP_112 SGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEDETAENGV
            20        30        40        50        60        70   

       60        70        80        90       100       110        
pF1KB8 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG
            80        90       100       110       120       130   

      120       130       140       150       160       170        
pF1KB8 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK
           140       150       160       170       180       190   

      180       190                              200       210     
pF1KB8 RIRMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPST
       :::::::::::::::::::                       ::::::::::::::::::
NP_112 RIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPST
           200       210       220       230       240       250   

         220       230                                             
pF1KB8 KAEFTSPPSLFKTGLPPSR------------------------------------RLPGA
       :::::::::::::::::::                                    :::::
NP_112 KAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGA
           260       270       280       290       300       310   

     240       250       260       270       280       290         
pF1KB8 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP
           320       330       340       350       360       370   

     300       310       320       330       340       350         
pF1KB8 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH
           380       390       400       410       420       430   

     360       370       380       390       400       410         
pF1KB8 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP
           440       450       460       470       480       490   

     420       430       440       450       460       470         
pF1KB8 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE
           500       510       520       530       540       550   

     480       490       500       510       520
pF1KB8 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
       :::::::::::::::::::::::::::::::::::::::::
NP_112 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
           560       570       580       590    

>>XP_016864155 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end  (556 aa)
 initn: 2343 init1: 2014 opt: 2016  Z-score: 868.5  bits: 170.4 E(85289): 1.2e-41
Smith-Waterman score: 3458; 93.5% identity (93.5% similar) in 552 aa overlap (5-520:5-556)

               10        20        30        40        50        60
pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSR------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQ
              190       200       210       220       230       240

                                        240       250       260    
pF1KB8 ------------------------------RLPGAIDVIGQTITISRVEGRRRANENSNI
                                     ::::::::::::::::::::::::::::::
XP_016 SQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNI
              250       260       270       280       290       300

          270       280       290       300       310       320    
pF1KB8 QVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG
              310       320       330       340       350       360

          330       340       350       360       370       380    
pF1KB8 APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARRE
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KB8 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KB8 RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAG
              490       500       510       520       530       540

          510       520
pF1KB8 SEPAPEQESTEATPAE
       ::::::::::::::::
XP_016 SEPAPEQESTEATPAE
              550      




520 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:15:09 2016 done: Fri Nov  4 14:15:10 2016
 Total Scan time: 11.180 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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