Result of FASTA (omim) for pF1KB8365
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8365, 472 aa
  1>>>pF1KB8365 472 - 472 aa - 472 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6905+/-0.000411; mu= -4.8131+/- 0.026
 mean_var=333.7249+/-68.171, 0's: 0 Z-trim(121.9): 134  B-trim: 2243 in 1/55
 Lambda= 0.070207
 statistics sampled from 39140 (39280) to 39140 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.461), width:  16
 Scan time:  8.040

The best scores are:                                      opt bits E(85289)
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 3216 339.3 1.4e-92
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte  ( 439) 2996 317.0 6.8e-86
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 1249 140.0 1.3e-32
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 1249 140.0 1.3e-32
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350)  773 91.7 3.4e-18
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465)  623 76.6 1.6e-13
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553)  622 76.6   2e-13
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495)  606 74.9 5.5e-13
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501)  554 69.7 2.1e-11
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319)  535 67.6 5.8e-11
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345)  515 65.6 2.5e-10
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420)  517 65.9 2.5e-10
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376)  514 65.5 2.9e-10
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373)  511 65.2 3.5e-10
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330)  491 63.1 1.3e-09
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478)  489 63.1   2e-09
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444)  480 62.1 3.5e-09
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439)  477 61.8 4.3e-09
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408)  470 61.1 6.7e-09
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416)  469 61.0 7.3e-09
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417)  469 61.0 7.3e-09
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378)  454 59.4 1.9e-08
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379)  454 59.4 1.9e-08
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403)  448 58.9 3.1e-08
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489)  425 56.6 1.8e-07
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421)  397 53.7 1.2e-06
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365)  379 51.8 3.7e-06
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573)  377 51.8 5.9e-06
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588)  377 51.8   6e-06
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596)  377 51.8 6.1e-06
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607)  377 51.8 6.2e-06
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622)  377 51.8 6.3e-06
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622)  377 51.8 6.3e-06
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622)  377 51.8 6.3e-06
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622)  377 51.8 6.3e-06
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630)  377 51.8 6.4e-06
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660)  377 51.8 6.6e-06
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570)  365 50.6 1.4e-05
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733)  365 50.7 1.7e-05
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283)  319 45.7  0.0002
NP_963853 (OMIM: 602681) forkhead box protein O3 [ ( 673)  320 46.1 0.00037
NP_001446 (OMIM: 602681) forkhead box protein O3 [ ( 673)  320 46.1 0.00037
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431)  308 44.7 0.00061
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061
XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431)  308 44.7 0.00061


>>NP_004487 (OMIM: 602294) hepatocyte nuclear factor 3-a  (472 aa)
 initn: 3216 init1: 3216 opt: 3216  Z-score: 1783.1  bits: 339.3 E(85289): 1.4e-92
Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 472 aa overlap (1-472:1-472)

               10        20        30        40        50        60
pF1KB8 MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 AASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLIT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 MAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 SNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SSGPGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSGPGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAY
              370       380       390       400       410       420

              430       440       450       460       470  
pF1KB8 EQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
              430       440       450       460       470  

>>XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte nucl  (439 aa)
 initn: 2996 init1: 2996 opt: 2996  Z-score: 1663.1  bits: 317.0 E(85289): 6.8e-86
Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 439 aa overlap (34-472:1-439)

            10        20        30        40        50        60   
pF1KB8 TVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPAS
                                     ::::::::::::::::::::::::::::::
XP_016                               MNSGLGSMNSMNTYMTMNTMTTSGNMTPAS
                                             10        20        30

            70        80        90       100       110       120   
pF1KB8 FNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAAS
               40        50        60        70        80        90

           130       140       150       160       170       180   
pF1KB8 MNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAI
              100       110       120       130       140       150

           190       200       210       220       230       240   
pF1KB8 QQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSY
              160       170       180       190       200       210

           250       260       270       280       290       300   
pF1KB8 WTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNP
              220       230       240       250       260       270

           310       320       330       340       350       360   
pF1KB8 SADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPISSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPISSG
              280       290       300       310       320       330

           370       380       390       400       410       420   
pF1KB8 PGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQA
              340       350       360       370       380       390

           430       440       450       460       470  
pF1KB8 LQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
              400       410       420       430         

>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b  (457 aa)
 initn: 1245 init1: 802 opt: 1249  Z-score: 706.5  bits: 140.0 E(85289): 1.3e-32
Smith-Waterman score: 1597; 55.9% identity (73.9% similar) in 499 aa overlap (1-472:1-457)

               10        20        30        40        50          
pF1KB8 MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTM---TTSG
       :::.::::::: :::.::::.  :.::::  ::::.::: ::.:::::.:..    . ::
NP_710 MLGAVKMEGHEPSDWSSYYAEP-EGYSSV--SNMNAGLG-MNGMNTYMSMSAAAMGSGSG
               10        20           30         40        50      

        60         70           80          90       100       110 
pF1KB8 NMTPASFNMS-YANPGLG---AGLSPGA--VAGMPGGSAGAMNSMTAAGVTAMGTALSPS
       ::. .:.::: :.. :..   ::.::::  .::: ::::::      :::..::  ::::
NP_710 NMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGM-GGSAGA------AGVAGMGPHLSPS
         60        70        80        90              100         

             120       130       140       150       160       170 
pF1KB8 GMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKP
        .. .:.: :..:.::.:::  ::  :::: :. ..:.:.:     : ::..::: ::::
NP_710 -LSPLGGQAAGAMGGLAPYAN-MNS-MSPM-YGQAGLSRAR-----DPKTYRRSYTHAKP
      110       120        130         140            150       160

             180       190       200       210       220       230 
pF1KB8 PYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKV
       ::::::::::::::.:.:::::::::::::::::.::::::::::::::::::::::.::
NP_710 PYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKV
              170       180       190       200       210       220

             240       250       260       270        280       290
pF1KB8 ARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAG-GGGGSGSGGSGAKGG
        ::::::::::.:::::::::::::::::::::::::::: .   ..:..::: ..: :.
NP_710 PRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGA
              230       240       250       260       270       280

              300       310       320       330       340       350
pF1KB8 PESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELK
         :. . . :..:....:             :. .:  .:::   .:.     :: .:::
NP_710 QASQAQLGEAAGPASETP------------AGTESPHSSASP-CQEHK----RGGLGELK
              290                   300       310            320   

                360           370         380       390       400  
pF1KB8 -TPASSTAPP-ISSGPG----ALASV--PASHPAHGLAPHESQLHLKGDPHYSFNHPFSI
        :::.. .::  . .::    : : .  :  ::  :: :   . ::: . ::.:::::::
NP_710 GTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHP--GLPP---EAHLKPEHHYAFNHPFSI
           330       340       350         360          370        

            410                420       430       440       450   
pF1KB8 NNLMSSSEQQH---------KLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIEPS
       :::::: .:.:         :.:.:::::...:  ::: .:.:: .: ..  :     : 
NP_710 NNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPL
      380       390       400       410       420       430        

           460       470  
pF1KB8 ALEPAYYQGVYSRPVLNTS
       : . .:::::::::..:.:
NP_710 AADTSYYQGVYSRPIMNSS
      440       450       

>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b  (463 aa)
 initn: 1245 init1: 802 opt: 1249  Z-score: 706.5  bits: 140.0 E(85289): 1.3e-32
Smith-Waterman score: 1597; 55.9% identity (73.9% similar) in 499 aa overlap (1-472:7-463)

                     10        20        30        40        50    
pF1KB8       MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTM-
             :::.::::::: :::.::::.  :.::::  ::::.::: ::.:::::.:..  
NP_068 MHSASSMLGAVKMEGHEPSDWSSYYAEP-EGYSSV--SNMNAGLG-MNGMNTYMSMSAAA
               10        20         30          40         50      

              60         70           80          90       100     
pF1KB8 --TTSGNMTPASFNMS-YANPGLG---AGLSPGA--VAGMPGGSAGAMNSMTAAGVTAMG
         . ::::. .:.::: :.. :..   ::.::::  .::: ::::::      :::..::
NP_068 MGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGM-GGSAGA------AGVAGMG
         60        70        80        90        100               

         110       120       130       140       150       160     
pF1KB8 TALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRS
         :::: .. .:.: :..:.::.:::  ::  :::: :. ..:.:.:     : ::..::
NP_068 PHLSPS-LSPLGGQAAGAMGGLAPYAN-MNS-MSPM-YGQAGLSRAR-----DPKTYRRS
     110        120       130         140        150            160

         170       180       190       200       210       220     
pF1KB8 YPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFN
       : ::::::::::::::::::.:.:::::::::::::::::.:::::::::::::::::::
NP_068 YTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFN
              170       180       190       200       210       220

         230       240       250       260       270        280    
pF1KB8 DCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAG-GGGGSGSGG
       :::.:: ::::::::::.:::::::::::::::::::::::::::: .   ..:..::: 
NP_068 DCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGK
              230       240       250       260       270       280

          290       300       310       320       330       340    
pF1KB8 SGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATG
       ..: :.  :. . . :..:....:             :. .:  .:::   .:.     :
NP_068 KAAAGAQASQAQLGEAAGPASETP------------AGTESPHSSASP-CQEHK----RG
              290       300                   310        320       

          350         360           370         380       390      
pF1KB8 GASELK-TPASSTAPP-ISSGPG----ALASV--PASHPAHGLAPHESQLHLKGDPHYSF
       : .::: :::.. .::  . .::    : : .  :  ::  :: :   . ::: . ::.:
NP_068 GLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHP--GLPP---EAHLKPEHHYAF
           330       340       350       360            370        

        400       410                420       430       440       
pF1KB8 NHPFSINNLMSSSEQQH---------KLDFKAYEQALQYSPYGSTLPASLPLGSASVTTR
       :::::::::::: .:.:         :.:.:::::...:  ::: .:.:: .: ..  : 
NP_068 NHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTG
      380       390       400       410       420       430        

       450       460       470  
pF1KB8 SPIEPSALEPAYYQGVYSRPVLNTS
           : : . .:::::::::..:.:
NP_068 LDASPLAADTSYYQGVYSRPIMNSS
      440       450       460   

>>NP_004488 (OMIM: 602295) hepatocyte nuclear factor 3-g  (350 aa)
 initn: 973 init1: 754 opt: 773  Z-score: 447.5  bits: 91.7 E(85289): 3.4e-18
Smith-Waterman score: 925; 42.9% identity (58.6% similar) in 473 aa overlap (1-472:1-350)

               10        20        30        40        50        60
pF1KB8 MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMT
       :::.::::.:. ..: ::: .. :.::  ::. . .    :  .:.:::.: ..     .
NP_004 MLGSVKMEAHDLAEW-SYYPEAGEVYS--PVTPVPT----MAPLNSYMTLNPLS-----S
               10         20          30            40             

               70        80        90       100       110       120
pF1KB8 PASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQ
       :      :   :: :  ::     .:.:  .       : .. .: .. : :.:. :.  
NP_004 P------YPPGGLPA--SP-----LPSGPLAP-----PAPAAPLGPTF-P-GLGVSGG--
             50               60             70          80        

              130       140       150       160       170       180
pF1KB8 AASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLIT
        .: .: :               ::   : . . :    : ..:   :::::::::::::
NP_004 -SSSSGYG---------------AP---GPGLVHGKEMPKGYRRPLAHAKPPYSYISLIT
          90                         100       110       120       

              190       200       210       220       230       240
pF1KB8 MAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGK
       :::::::.::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_004 MAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGK
       130       140       150       160       170       180       

              250       260       270       280       290       300
pF1KB8 GSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGA
       ::::.:::.:::::::::::::::::: :..   ::.:.. .  .:. :.  :   :.. 
NP_004 GSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGT-GSAASTTTPAA-
       190       200       210       220       230        240      

              310       320       330       340       350       360
pF1KB8 SNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPI
          .. ::               : : : : :.   ..:  .  :: .  .:::::  : 
NP_004 ---TVTSP---------------PQPPPPA-PEPEAQGGEDV--GALDCGSPASST--PY
            250                       260         270       280    

              370       380       390       400        410         
pF1KB8 SSGPGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMS-SSEQQHKLDFKA
        .:      .:.              .:: :  :.:::::::::::: ..    :::   
NP_004 FTG----LELPG--------------ELKLDAPYNFNHPFSINNLMSEQTPAPPKLD---
                290                     300       310       320    

     420       430       440       450       460       470  
pF1KB8 YEQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
           . .. ::.        :.         ::.    .::::.::: .::.:
NP_004 ----VGFGGYGAE-------GG---------EPG----VYYQGLYSRSLLNAS
                 330                           340       350

>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo  (465 aa)
 initn: 504 init1: 504 opt: 623  Z-score: 363.8  bits: 76.6 E(85289): 1.6e-13
Smith-Waterman score: 629; 38.7% identity (60.2% similar) in 344 aa overlap (128-454:84-420)

       100       110       120       130       140       150       
pF1KB8 AAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGG
                                     :   :  .:  .  : : .. : . :::::
NP_004 RRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGG
            60        70        80        90       100       110   

       160       170       180       190       200       210       
pF1KB8 DAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNS
       .: .  .. : .:::::::.:::::: :.:.: :::::: ..:   :::::..   ::::
NP_004 SAGSGAKN-PLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS
           120        130       140       150       160       170  

       220       230       240       250       260       270       
pF1KB8 IRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEK--QPGAG
       :::.::.::::::. : : .::::.:::: :.:..::.:: .:::.:::: .    :.:.
NP_004 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPPNAA
            180       190       200       210       220       230  

         280       290       300          310       320       330  
pF1KB8 GGGGSGSGGSGAKGGPESRKDPSGASN---PSADSPLHRGVHGKTGQLEGAPAPGPAASP
       .. .    :.:: ::     ::..:.    :.   : :   .:  :   :   : : : :
NP_004 AAESLLLRGAGAAGGA---GDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLP-PYAPP
            240          250       260       270       280         

            340       350       360        370       380           
pF1KB8 QTLDHSGATATGGASELKTPASSTAPPISSGPGA-LASVPASHPAHGLA-----PHESQL
       ..:  ..:.:...:. .. : :   ::   : .: :: .  ..  : :.     :  .. 
NP_004 SAL-FAAAAAAAAAAAFH-PHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASA
      290        300        310       320       330       340      

        390         400       410       420         430       440  
pF1KB8 HLKGDPHYSF--NHPFSINNLMSSSEQQHKLDFKAYEQAL--QYSPYGSTLPASLPLGSA
          : :  :     ::::......:         : . :   : ::  : . :    ::.
NP_004 AKAGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSS
        350       360       370       380       390       400      

              450       460       470                             
pF1KB8 S--VTTRSPIEPSALEPAYYQGVYSRPVLNTS                           
       .   .... . :.:                                             
NP_004 GGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC
        410       420       430       440       450       460     

>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr  (553 aa)
 initn: 556 init1: 523 opt: 622  Z-score: 362.2  bits: 76.6 E(85289): 2e-13
Smith-Waterman score: 645; 37.5% identity (60.7% similar) in 392 aa overlap (109-472:9-369)

       80        90       100       110          120           130 
pF1KB8 PGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGA---MGAQQ----AASMNGLGPYA
                                     ::...:.   .:..:    ::.  . : :.
NP_001                       MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYT
                                     10        20        30        

             140       150       160             170       180     
pF1KB8 AAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPH------AKPPYSYISLITMAIQQ
       :   : :: ... :..   ..   :: :...    :.      .:::::::.:::::::.
NP_001 AMPAP-MSVYSH-PAH---AEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQN
       40          50           60        70        80        90   

         190       200       210       220       230       240     
pF1KB8 APSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWT
       ::.: .::. :::.::: ::.::.:.: :::::::.::.:.::::: :.  :::::::::
NP_001 APDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWT
           100       110       120       130       140       150   

         250       260       270       280       290       300     
pF1KB8 LHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGA---SN
       : ::: :::::: .:::..:::   .  :       .     .  : .:. : .    ..
NP_001 LDPDSYNMFENGSFLRRRRRFK---KKDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQAD
           160       170          180       190       200       210

            310       320       330       340          350         
pF1KB8 PSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGAS---ELKTPASSTAPP
        .: .:    :. .  . :..  :.:   :: :. ..: ..:.:.   ....: ::..  
NP_001 GNAPGPQPPPVRIQDIKTENGTCPSP---PQPLSPAAALGSGSAAAVPKIESPDSSSSS-
              220       230          240       250       260       

     360          370        380       390       400       410     
pF1KB8 ISSG---PGALASV-PASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKL
       .:::   ::.: :. : :  .   ::          ::.:  . ::..:.:.:       
NP_001 LSSGSSPPGSLPSARPLSLDGADSAP-PPPAPSAPPPHHS--QGFSVDNIMTS-------
        270       280       290        300         310             

         420       430         440       450       460          470
pF1KB8 DFKAYEQALQYSPYGST--LPASLPLGSASVTTRSPIEPSALEPAYYQG---VYSRPVLN
               :. :: ...  : ..: :.::....:. : :     ::  :   .:: :  .
NP_001 --------LRGSPQSAAAELSSGL-LASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQ
                320       330        340       350       360       

                                                                   
pF1KB8 TS                                                          
       ::                                                          
NP_001 TSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDP
       370       380       390       400       410       420       

>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo  (495 aa)
 initn: 605 init1: 494 opt: 606  Z-score: 354.1  bits: 74.9 E(85289): 5.5e-13
Smith-Waterman score: 612; 42.9% identity (61.0% similar) in 282 aa overlap (110-381:82-345)

      80        90       100       110       120       130         
pF1KB8 GAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMS
                                     : .... ::  ::. .. :: :::     .
NP_004 LPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGA--AAAAGSPGPGAAAARGAAG
              60        70        80        90         100         

     140       150       160       170       180       190         
pF1KB8 PMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQW
       :    ::         :: :    :: : .:::::::.:::::: :.:.: :::::: ..
NP_004 PGPGPPS---------GGAAT---RS-PLVKPPYSYIALITMAILQSPKKRLTLSEICEF
     110                120           130       140       150      

     200       210       220       230       240       250         
pF1KB8 IMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCY
       :   :::::..   :::::::.::.::::::. : : .::::.:::: :.:..::.:: .
NP_004 ISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSF
        160       170       180       190       200       210      

     260       270       280        290       300       310        
pF1KB8 LRRQKRFKCEKQPGAGGGGGSGSGGSGA-KGGPESRKDPSGASNPSADSPLHRGV-HGKT
       :::.::::  .::                .::  .  :: ::  :.  .    :  .: .
NP_004 LRRRKRFK--RQPLPPPHPHPHPHPELLLRGGAAAAGDP-GAFLPGFAAYGAYGYGYGLA
        220         230       240       250        260       270   

       320       330       340          350            360         
pF1KB8 GQLEGAPAPGPAASPQTLDHSGATATGGAS---ELKTPASSTA-----PPISSGPGALAS
           ::: ::::  :.   :. : :...:.   .:..: . .:     :: .:  .. .:
NP_004 LPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGS
           280       290       300       310       320       330   

     370       380       390       400       410       420         
pF1KB8 VPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQYSPY
       .::  :: : .:                                                
NP_004 APAPAPASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKT
           340       350       360       370       380       390   

>>NP_005242 (OMIM: 153400,602402) forkhead box protein C  (501 aa)
 initn: 600 init1: 513 opt: 554  Z-score: 325.6  bits: 69.7 E(85289): 2.1e-11
Smith-Waterman score: 589; 35.7% identity (58.1% similar) in 370 aa overlap (104-436:1-370)

            80        90       100       110       120       130   
pF1KB8 GAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAA
                                     : .  : :  .:.:.    : ..    :..
NP_005                               MQARYSVSDPNALGVVPYLSEQNYYRAAGS
                                             10        20        30

           140       150       160            170       180        
pF1KB8 MNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHA-----KPPYSYISLITMAIQQAPS
       ..   :::.   ..  .  :: : .   ...  : :     :::::::.:::::::.:: 
NP_005 YGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPE
               40        50        60        70        80        90

      190       200       210       220       230       240        
pF1KB8 KMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHP
       : .::. :::.::: ::.::.:.: :::::::.::.:.::::: :.  :::::::::: :
NP_005 KKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDP
              100       110       120       130       140       150

      250       260                   270       280       290      
pF1KB8 DSGNMFENGCYLRRQKRFKCE------------KQPGAGGGGGSGSGGSGAKGGPESRKD
       :: :::::: .:::..::: .            :.:  ... :. .    : .  :..: 
NP_005 DSYNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKK
              160       170       180       190       200       210

           300       310       320          330         340        
pF1KB8 ---PSGASNPSADSPLHRGVHGKTGQLEGAP---APGPAASPQ-TL-DHSGATATG--GA
           : :..:.     .  . .  . :.:.:   :  ::.::. .: .: .:. .:  : 
NP_005 VVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGF
              220       230       240       250       260       270

        350          360         370       380           390       
pF1KB8 SELKTPASSTAPP---ISSGPG--ALASVPASHPAHGLAP----HESQLHLKGDPHYSFN
       :  .  .  :.::   .: : :  .:.  : . :  .  :    .     :..    ...
NP_005 SVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQ
              280       290       300       310       320       330

       400       410        420       430       440       450      
pF1KB8 HPFSINNLMSSSEQQ-HKLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALE
         .   .:....:.  :     : ..::.  : : : : :                    
NP_005 CSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQ
              340       350       360       370       380       390

        460       470                                              
pF1KB8 PAYYQGVYSRPVLNTS                                            
                                                                   
NP_005 HHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNV
              400       410       420       430       440       450

>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr  (319 aa)
 initn: 536 init1: 462 opt: 535  Z-score: 317.8  bits: 67.6 E(85289): 5.8e-11
Smith-Waterman score: 535; 36.5% identity (60.2% similar) in 304 aa overlap (99-390:2-291)

       70        80        90       100       110       120        
pF1KB8 ANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLG
                                     :: . :    . ::. :. :  : :    .
NP_036                              MAGRSDMDPPAAFSGFPALPAV-APSGPPPS
                                            10        20         30

      130       140       150          160       170       180     
pF1KB8 PYAAAMNPCMSPMAYAPSNLGRSRAG---GGGDAKTFKRSYPHAKPPYSYISLITMAIQQ
       : :.: .:   :   :    ::..:.   . : ..  .:   ..:::::::.::.::. .
NP_036 PLAGA-EPGREPEEAAA---GRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAH
                40           50        60        70        80      

         190       200       210       220       230       240     
pF1KB8 APSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWT
       ::.. :::. ::..: . : .::.. ..:::::::.:..::::::: : : .::::.:::
NP_036 APGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWT
         90       100       110       120       130       140      

         250       260       270        280            290         
pF1KB8 LHPDSGNMFENGCYLRRQKRFKCEKQPG-AGGGGGSG-----SGGSGAKGGPESRKDPSG
       : : ...::.:: .:::.::::  . :. :... :       .  . : :       ::.
NP_036 LDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSA
        150       160       170       180       190       200      

     300       310         320       330       340       350       
pF1KB8 ASNPSADSPLHR--GVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTA
       . .::  . :    .. .   .: :  :: :           :.  ..:. .   :....
NP_036 GPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCC--------AAPDAAAAAFPPCAAAAS
        210       220       230       240               250        

       360        370       380       390       400       410      
pF1KB8 PPISSG-PGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLD
       ::. :  :  :. .::..:. :  : :  : : :                          
NP_036 PPLYSQVPDRLV-LPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLER
      260       270        280       290       300       310       

        420       430       440       450       460       470  
pF1KB8 FKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
                                                               
NP_036 YL                                                      
                                                               




472 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:15:54 2016 done: Fri Nov  4 12:15:56 2016
 Total Scan time:  8.040 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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