Result of FASTA (omim) for pF1KB8353
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8353, 347 aa
  1>>>pF1KB8353 347 - 347 aa - 347 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0991+/-0.000353; mu= 17.1595+/- 0.022
 mean_var=64.2169+/-12.745, 0's: 0 Z-trim(114.2): 60  B-trim: 213 in 1/55
 Lambda= 0.160048
 statistics sampled from 23881 (23943) to 23881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.281), width:  16
 Scan time:  6.090

The best scores are:                                      opt bits E(85289)
NP_079103 (OMIM: 607226) histone deacetylase 11 is ( 347) 2316 543.5 2.6e-154
XP_011532433 (OMIM: 607226) PREDICTED: histone dea ( 319) 2116 497.3 1.9e-140
XP_005265548 (OMIM: 607226) PREDICTED: histone dea ( 319) 2116 497.3 1.9e-140
NP_001129513 (OMIM: 607226) histone deacetylase 11 ( 296) 1605 379.2  6e-105
XP_011532437 (OMIM: 607226) PREDICTED: histone dea ( 225) 1507 356.5 3.1e-98
XP_011532434 (OMIM: 607226) PREDICTED: histone dea ( 240) 1224 291.2 1.5e-78
NP_001317565 (OMIM: 607226) histone deacetylase 11 ( 268) 1224 291.2 1.7e-78
XP_006713401 (OMIM: 607226) PREDICTED: histone dea ( 268)  908 218.3 1.5e-56
XP_016862723 (OMIM: 607226) PREDICTED: histone dea ( 240)  845 203.7 3.4e-52
NP_001518 (OMIM: 605164) histone deacetylase 2 [Ho ( 488)  305 79.2 2.1e-14
XP_011534090 (OMIM: 605164) PREDICTED: histone dea ( 458)  298 77.6   6e-14
XP_016866288 (OMIM: 605164) PREDICTED: histone dea ( 458)  298 77.6   6e-14
NP_004955 (OMIM: 601241) histone deacetylase 1 [Ho ( 482)  292 76.2 1.6e-13
NP_060956 (OMIM: 300269) histone deacetylase 8 iso ( 377)  278 72.9 1.3e-12
XP_011529289 (OMIM: 300269) PREDICTED: histone dea ( 379)  278 72.9 1.3e-12
XP_011529288 (OMIM: 300269) PREDICTED: histone dea ( 441)  278 72.9 1.4e-12
XP_016885135 (OMIM: 300269) PREDICTED: histone dea ( 274)  247 65.7 1.4e-10
NP_003874 (OMIM: 605166) histone deacetylase 3 [Ho ( 428)  241 64.4 5.2e-10
NP_001159891 (OMIM: 300269) histone deacetylase 8  ( 256)  192 52.9 8.7e-07
NP_001152758 (OMIM: 608544) histone deacetylase 10 ( 649)  194 53.7 1.4e-06
NP_114408 (OMIM: 608544) histone deacetylase 10 is ( 669)  194 53.7 1.4e-06
XP_016885136 (OMIM: 300269) PREDICTED: histone dea ( 268)  175 49.0 1.4e-05
XP_016885130 (OMIM: 300269) PREDICTED: histone dea ( 389)  175 49.1 1.9e-05
XP_016885129 (OMIM: 300269) PREDICTED: histone dea ( 415)  175 49.1   2e-05
NP_001159890 (OMIM: 300269) histone deacetylase 8  ( 286)  157 44.9 0.00026
XP_016885131 (OMIM: 300269) PREDICTED: histone dea ( 350)  157 44.9 0.00031
NP_478056 (OMIM: 606543) histone deacetylase 9 iso (1011)  162 46.4 0.00033
NP_001308826 (OMIM: 606543) histone deacetylase 9  (1025)  162 46.4 0.00033
XP_016868317 (OMIM: 606543) PREDICTED: histone dea (1025)  162 46.4 0.00033
NP_001308806 (OMIM: 606543) histone deacetylase 9  (1025)  162 46.4 0.00033
XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035)  162 46.4 0.00033
XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038)  162 46.4 0.00033
XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038)  162 46.4 0.00033
XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043)  162 46.4 0.00033
XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043)  162 46.4 0.00033
XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043)  162 46.4 0.00033
XP_011513936 (OMIM: 606543) PREDICTED: histone dea (1044)  162 46.4 0.00033
NP_001308797 (OMIM: 606543) histone deacetylase 9  (1044)  162 46.4 0.00033
NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066)  162 46.4 0.00034
XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066)  162 46.4 0.00034
XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069)  162 46.4 0.00034
XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069)  162 46.4 0.00034
NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069)  162 46.4 0.00034
XP_011513939 (OMIM: 606543) PREDICTED: histone dea (1071)  162 46.4 0.00034
XP_011513938 (OMIM: 606543) PREDICTED: histone dea (1071)  162 46.4 0.00034
XP_011513937 (OMIM: 606543) PREDICTED: histone dea (1074)  162 46.4 0.00034
XP_011513950 (OMIM: 606543) PREDICTED: histone dea (1074)  162 46.4 0.00034
XP_011513951 (OMIM: 606543) PREDICTED: histone dea (1074)  162 46.4 0.00034
XP_011513931 (OMIM: 606543) PREDICTED: histone dea (1088)  162 46.4 0.00035
XP_011513933 (OMIM: 606543) PREDICTED: histone dea (1096)  162 46.4 0.00035


>>NP_079103 (OMIM: 607226) histone deacetylase 11 isofor  (347 aa)
 initn: 2316 init1: 2316 opt: 2316  Z-score: 2891.4  bits: 543.5 E(85289): 2.6e-154
Smith-Waterman score: 2316; 100.0% identity (100.0% similar) in 347 aa overlap (1-347:1-347)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
              250       260       270       280       290       300

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
              310       320       330       340       

>>XP_011532433 (OMIM: 607226) PREDICTED: histone deacety  (319 aa)
 initn: 2116 init1: 2116 opt: 2116  Z-score: 2642.3  bits: 497.3 E(85289): 1.9e-140
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 319 aa overlap (29-347:1-319)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                   ::::::::::::::::::::::::::::::::
XP_011                             MGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                           10        20        30  

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
            100       110       120       130       140       150  

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
            160       170       180       190       200       210  

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
            220       230       240       250       260       270  

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
            280       290       300       310         

>>XP_005265548 (OMIM: 607226) PREDICTED: histone deacety  (319 aa)
 initn: 2116 init1: 2116 opt: 2116  Z-score: 2642.3  bits: 497.3 E(85289): 1.9e-140
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 319 aa overlap (29-347:1-319)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                   ::::::::::::::::::::::::::::::::
XP_005                             MGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                           10        20        30  

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
            100       110       120       130       140       150  

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
            160       170       180       190       200       210  

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
            220       230       240       250       260       270  

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
            280       290       300       310         

>>NP_001129513 (OMIM: 607226) histone deacetylase 11 iso  (296 aa)
 initn: 1605 init1: 1605 opt: 1605  Z-score: 2005.1  bits: 379.2 E(85289): 6e-105
Smith-Waterman score: 1906; 92.8% identity (92.8% similar) in 319 aa overlap (29-347:1-296)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                   ::::::::::::::::::::::::::::::::
NP_001                             MGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                           10        20        30  

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::                       :::::::::::::
NP_001 VEAREASEEDLLVVHTRRYLNELK-----------------------RKVLRPLRTQTGG
             40        50                               60         

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
      70        80        90       100       110       120         

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
     130       140       150       160       170       180         

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
     190       200       210       220       230       240         

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
     250       260       270       280       290      

>>XP_011532437 (OMIM: 607226) PREDICTED: histone deacety  (225 aa)
 initn: 1507 init1: 1507 opt: 1507  Z-score: 1884.6  bits: 356.5 E(85289): 3.1e-98
Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 225 aa overlap (123-347:1-225)

            100       110       120       130       140       150  
pF1KB8 TEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGF
                                     ::::::::::::::::::::::::::::::
XP_011                               MAGKLAVERGWAINVGGGFHHCSSDRGGGF
                                             10        20        30

            160       170       180       190       200       210  
pF1KB8 CAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGD
               40        50        60        70        80        90

            220       230       240       250       260       270  
pF1KB8 RFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLS
              100       110       120       130       140       150

            280       290       300       310       320       330  
pF1KB8 ISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSV
              160       170       180       190       200       210

            340       
pF1KB8 SAQNSDTPLLPPAVP
       :::::::::::::::
XP_011 SAQNSDTPLLPPAVP
              220     

>>XP_011532434 (OMIM: 607226) PREDICTED: histone deacety  (240 aa)
 initn: 1224 init1: 1224 opt: 1224  Z-score: 1531.0  bits: 291.2 E(85289): 1.5e-78
Smith-Waterman score: 1408; 75.2% identity (75.2% similar) in 319 aa overlap (29-347:1-240)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                   ::::::::::::::::::::::::::::::::
XP_011                             MGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                           10        20        30  

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::                                    
XP_011 VEAREASEEDLLVVHTRRYLNELK------------------------------------
             40        50                                          

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
                                                  :::::::::::::::::
XP_011 -------------------------------------------FLFERVEGISRATIIDL
                                                    60        70   

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
            80        90       100       110       120       130   

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
           140       150       160       170       180       190   

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
           200       210       220       230       240

>>NP_001317565 (OMIM: 607226) histone deacetylase 11 iso  (268 aa)
 initn: 1224 init1: 1224 opt: 1224  Z-score: 1530.3  bits: 291.2 E(85289): 1.7e-78
Smith-Waterman score: 1608; 77.2% identity (77.2% similar) in 347 aa overlap (1-347:1-268)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::                                    
NP_001 VEAREASEEDLLVVHTRRYLNELK------------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
                                                  :::::::::::::::::
NP_001 -------------------------------------------FLFERVEGISRATIIDL
                                                      90       100 

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
             110       120       130       140       150       160 

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
             170       180       190       200       210       220 

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
             230       240       250       260        

>>XP_006713401 (OMIM: 607226) PREDICTED: histone deacety  (268 aa)
 initn: 1739 init1: 908 opt: 908  Z-score: 1136.0  bits: 218.3 E(85289): 1.5e-56
Smith-Waterman score: 1585; 76.9% identity (77.2% similar) in 347 aa overlap (1-347:1-268)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       :::::::::::::::::                                           
XP_006 TIMAGKLAVERGWAINV-------------------------------------------
              130                                                  

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
                                           .:::::::::::::::::::::::
XP_006 ------------------------------------EAIRRKVELEWGTEDDEYLDKVER
                                           140       150       160 

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
             170       180       190       200       210       220 

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
             230       240       250       260        

>>XP_016862723 (OMIM: 607226) PREDICTED: histone deacety  (240 aa)
 initn: 1539 init1: 845 opt: 845  Z-score: 1058.1  bits: 203.7 E(85289): 3.4e-52
Smith-Waterman score: 1385; 74.9% identity (75.2% similar) in 319 aa overlap (29-347:1-240)

               10        20        30        40        50        60
pF1KB8 MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                   ::::::::::::::::::::::::::::::::
XP_016                             MGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
                                           10        20        30  

               70        80        90       100       110       120
pF1KB8 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB8 TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
       :::::::::::::::::                                           
XP_016 TIMAGKLAVERGWAINV-------------------------------------------
            100                                                    

              190       200       210       220       230       240
pF1KB8 DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
                                           .:::::::::::::::::::::::
XP_016 ------------------------------------EAIRRKVELEWGTEDDEYLDKVER
                                         110       120       130   

              250       260       270       280       290       300
pF1KB8 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
           140       150       160       170       180       190   

              310       320       330       340       
pF1KB8 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
           200       210       220       230       240

>>NP_001518 (OMIM: 605164) histone deacetylase 2 [Homo s  (488 aa)
 initn: 200 init1: 103 opt: 305  Z-score: 379.7  bits: 79.2 E(85289): 2.1e-14
Smith-Waterman score: 305; 27.4% identity (56.9% similar) in 288 aa overlap (35-307:29-307)

           10        20        30        40        50        60    
pF1KB8 TQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAR
                                     ::.   .   . :.: .  :     . . .
NP_001   MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPH
                 10        20        30        40        50        

           70        80        90       100       110           120
pF1KB8 EASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPL----RTQTGG
       .:. :..   :. .:.. :. :.   ...:    .   :   .  :.  :    . .:::
NP_001 KATAEEMTKYHSDEYIKFLR-SIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGG
       60        70         80        90       100       110       

              130          140       150       160       170       
pF1KB8 TIMAGKLAVER---GWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATI
       .. :: . ..:     :.: .::.:: ......:::   ::.:::   .: ..  .:.  
NP_001 SV-AGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYHQRVLY
        120       130       140       150       160          170   

       180       190       200        210            220           
pF1KB8 IDLDAHQGNGHERDFMDDKRVYIMDVYNR-HIYPG-----DRFAKQAIRRKVELEW--GT
       ::.: :.:.: :. :.   ::. .. ..  . .::     :  : ..    :..    : 
NP_001 IDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGI
           180       190       200       210       220       230   

     230       240       250       260       270       280         
pF1KB8 EDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMV
       .:. : .  .  :.: .. . :..:: . :.: : ::::: ....  : .:  :.:    
NP_001 DDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVV----
           240       250       260       270       280             

     290       300       310       320       330       340         
pF1KB8 RGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP  
       .   .:.::. .:::  :                                          
NP_001 KTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPS
     290       300       310       320       330       340         




347 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:00:55 2016 done: Fri Nov  4 12:00:55 2016
 Total Scan time:  6.090 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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