Result of FASTA (omim) for pF1KB8180
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8180, 425 aa
  1>>>pF1KB8180 425 - 425 aa - 425 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8762+/-0.000304; mu= 20.8408+/- 0.019
 mean_var=87.4622+/-19.490, 0's: 0 Z-trim(117.8): 616  B-trim: 2925 in 2/55
 Lambda= 0.137140
 statistics sampled from 29406 (30183) to 29406 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.354), width:  16
 Scan time:  7.340

The best scores are:                                      opt bits E(85289)
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 2860 575.7 7.7e-164
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 2860 575.7 7.7e-164
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 2860 575.7 7.7e-164
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 2466 497.7 2.1e-140
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 1892 384.2 3.6e-106
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 1892 384.2 3.7e-106
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  500 108.8 2.8e-23
NP_444264 (OMIM: 607449) neuropeptide FF receptor  ( 420)  490 106.8 1.1e-22
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423)  490 106.8 1.1e-22
NP_004876 (OMIM: 607449) neuropeptide FF receptor  ( 522)  490 106.9 1.3e-22
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  447 98.3 4.1e-20
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  430 94.9 3.9e-19
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381)  430 94.9 3.9e-19
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  430 94.9 3.9e-19
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370)  427 94.2 5.7e-19
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446)  413 91.6 4.4e-18
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390)  411 91.1 5.3e-18
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic  ( 477)  404 89.8 1.6e-17
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393)  403 89.5 1.6e-17
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572)  403 89.7 2.1e-17
NP_000721 (OMIM: 118444) cholecystokinin receptor  ( 428)  399 88.8 2.9e-17
NP_057624 (OMIM: 605569) probable G-protein couple ( 423)  388 86.6 1.3e-16
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384)  386 86.2 1.6e-16
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384)  386 86.2 1.6e-16
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348)  385 85.9 1.7e-16
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311)  379 84.7 3.7e-16
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407)  379 84.8 4.4e-16
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384)  378 84.6 4.8e-16
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  378 84.6 4.8e-16
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  378 84.6 4.8e-16
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516)  373 83.7 1.2e-15
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447)  368 82.7 2.1e-15
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465)  368 82.7 2.2e-15
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398)  366 82.2 2.6e-15
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445)  366 82.3 2.8e-15
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445)  366 82.3 2.8e-15
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445)  366 82.3 2.8e-15
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445)  366 82.3 2.8e-15
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445)  366 82.3 2.8e-15
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  366 82.3 2.8e-15
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  366 82.3 2.8e-15
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  366 82.3 2.8e-15
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390)  360 81.0 5.8e-15
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269)  358 80.4 5.9e-15
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349)  358 80.6 7.1e-15
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380)  356 80.2 9.8e-15
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic  ( 408)  356 80.2   1e-14
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409)  356 80.2   1e-14
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190)  352 79.1 1.1e-14
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384)  351 79.2   2e-14


>>XP_016856594 (OMIM: 602392) PREDICTED: orexin receptor  (425 aa)
 initn: 2860 init1: 2860 opt: 2860  Z-score: 3062.4  bits: 575.7 E(85289): 7.7e-164
Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)

               10        20        30        40        50        60
pF1KB8 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
              370       380       390       400       410       420

            
pF1KB8 TTVLP
       :::::
XP_016 TTVLP
            

>>XP_016856595 (OMIM: 602392) PREDICTED: orexin receptor  (425 aa)
 initn: 2860 init1: 2860 opt: 2860  Z-score: 3062.4  bits: 575.7 E(85289): 7.7e-164
Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)

               10        20        30        40        50        60
pF1KB8 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
              370       380       390       400       410       420

            
pF1KB8 TTVLP
       :::::
XP_016 TTVLP
            

>>NP_001516 (OMIM: 602392) orexin receptor type 1 [Homo   (425 aa)
 initn: 2860 init1: 2860 opt: 2860  Z-score: 3062.4  bits: 575.7 E(85289): 7.7e-164
Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)

               10        20        30        40        50        60
pF1KB8 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
              370       380       390       400       410       420

            
pF1KB8 TTVLP
       :::::
NP_001 TTVLP
            

>>XP_016856596 (OMIM: 602392) PREDICTED: orexin receptor  (389 aa)
 initn: 2448 init1: 2448 opt: 2466  Z-score: 2641.6  bits: 497.7 E(85289): 2.1e-140
Smith-Waterman score: 2466; 96.6% identity (97.7% similar) in 384 aa overlap (1-382:1-381)

               10        20        30        40        50        60
pF1KB8 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
              310       320       330       340       350       360

              370         380       390       400       410        
pF1KB8 LSGKFREQFKAAFSC--CLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLT
       :::  .:. . :.::  : ::  :                                    
XP_016 LSG-CKEK-SLALSCPSC-PGHDPHLAAALCS                            
                370        380                                     

>>NP_001517 (OMIM: 602393) orexin receptor type 2 [Homo   (444 aa)
 initn: 1853 init1: 1261 opt: 1892  Z-score: 2027.1  bits: 384.2 E(85289): 3.6e-106
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (17-425:24-433)

                      10        20        30         40        50  
pF1KB8        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                              ..::   : ::.:: :::::::.::.::.:::::::.
NP_001 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB8 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
NP_001 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KB8 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
NP_001 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KB8 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
NP_001 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
              190       200       210       220       230       240

            240       250         260       270        280         
pF1KB8 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
NP_001 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
              250       260       270            280       290     

     290       300       310       320       330       340         
pF1KB8 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
NP_001 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
         300       310       320       330       340       350     

     350       360       370       380       390        400        
pF1KB8 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
       ::::::::::::::::::.::::::::  :.      .    :.:. :.:::. :     
NP_001 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
         360       370       380       390       400       410     

        410       420                
pF1KB8 SISKISEHVVLTSVTTVLP           
       .:::.::.:::::..: ::           
NP_001 NISKLSEQVVLTSIST-LPAANGAGPLQNW
         420       430        440    

>>XP_016866287 (OMIM: 602393) PREDICTED: orexin receptor  (461 aa)
 initn: 1853 init1: 1261 opt: 1892  Z-score: 2026.9  bits: 384.2 E(85289): 3.7e-106
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (17-425:24-433)

                      10        20        30         40        50  
pF1KB8        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                              ..::   : ::.:: :::::::.::.::.:::::::.
XP_016 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB8 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
XP_016 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KB8 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KB8 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
              190       200       210       220       230       240

            240       250         260       270        280         
pF1KB8 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
XP_016 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
              250       260       270            280       290     

     290       300       310       320       330       340         
pF1KB8 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
         300       310       320       330       340       350     

     350       360       370       380       390        400        
pF1KB8 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
       ::::::::::::::::::.::::::::  :.      .    :.:. :.:::. :     
XP_016 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
         360       370       380       390       400       410     

        410       420                                 
pF1KB8 SISKISEHVVLTSVTTVLP                            
       .:::.::.:::::..: ::                            
XP_016 NISKLSEQVVLTSIST-LPAANGAGPLQNWCLQQGPPSSLPSTWLDV
         420       430        440       450       460 

>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H  (430 aa)
 initn: 707 init1: 396 opt: 500  Z-score: 538.8  bits: 108.8 E(85289): 2.8e-23
Smith-Waterman score: 650; 33.9% identity (60.3% similar) in 401 aa overlap (2-398:4-357)

                 10        20        30        40        50        
pF1KB8   MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFV
          :::  :...  .  .. . . . :  .  :  :    : . .    ..:.::. .:.
NP_071 MEGEPSQPPNSSWPLSQNGTN-TEATPATNLTFSSY----YQHTSPVAAMFIVAYALIFL
               10        20         30            40        50     

       60        70        80        90       100       110        
pF1KB8 VALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHAL
       . .:::::::. : .:.::.::::.::.::...:.::  .:.:..:. ..  .: : .: 
NP_071 LCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNAT
          60        70        80        90       100       110     

      120       130       140       150       160       170        
pF1KB8 CKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVP
       ::.   .:..:::..:.::  ::..:.  : ::.  : : :.:  .:  :::..: :: :
NP_071 CKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCP
         120       130       140       150       160       170     

      180           190       200       210       220       230    
pF1KB8 QAAVM----ECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMA
       .:...    :    . .  ::.  .  : : : .  . ..: . .:   :::::.:... 
NP_071 SAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVM
         180       190       200       210       220       230     

          240       250       260       270       280       290    
pF1KB8 YFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARR
       : .: :::   : ::           :.   :  : .     .:::          : : 
NP_071 YARIARKL--CQAPG-----------PAP--GGEEAA-----DPRAS---------RRRA
         240                    250              260               

          300       310       320       330       340       350    
pF1KB8 KTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAAN
       ....::..: : :.: .::. .: .:   .:..   . . ..   : :.:::.. ::.::
NP_071 RVVHMLVMVALFFTLSWLPLWALLLLID-YGQLSAPQLHLVTVYAFPFAHWLAFFNSSAN
        270       280       290        300       310       320     

          360       370       380       390       400       410    
pF1KB8 PIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEH
       ::::.... .::. :.:::   :     :       :: :.:::                
NP_071 PIIYGYFNENFRRGFQAAFRARL-----C-------PRPSGSHKEAYSERPGGLLHRRVF
         330       340                   350       360       370   

          420                                                   
pF1KB8 VVLTSVTTVLP                                              
                                                                
NP_071 VVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
           380       390       400       410       420       430

>>NP_444264 (OMIM: 607449) neuropeptide FF receptor 2 is  (420 aa)
 initn: 638 init1: 402 opt: 490  Z-score: 528.3  bits: 106.8 E(85289): 1.1e-22
Smith-Waterman score: 618; 33.2% identity (60.3% similar) in 355 aa overlap (27-373:27-348)

               10        20        30        40        50        60
pF1KB8 MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
                                 : :  . :.   ::.  :   ..: .:  .: . 
NP_444 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYV-NYYLHQPQVAAIFIISYFLIFFLC
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KB8 LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
       ..:::.::. : ::.::.:::: ::.::...:.::  .:.: .:: .:  .: ::...::
NP_444 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCK
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB8 VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
       .   .:..::...:.::  ::.::.  . .:.  : : . :   :. ::.....:: :.:
NP_444 ISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSA
     120       130       140       150       160       170         

              190       200               210       220       230  
pF1KB8 AVMECSSVLPELANRTRLFSV--------CDERWADDLYPKIYHSCFFIVTYLAPLGLMA
       ....   :  :   :.:: :         : : : .. . ::: . .:   :::::.:..
NP_444 VMLH---VQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIV
     180          190       200       210       220       230      

            240       250       260       270       280       290  
pF1KB8 MAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRA
       . : .:  .:.   .: :     ..:.  :                            : 
NP_444 IMYGRIGISLFRAAVPHTGRKNQEQWHVVS----------------------------RK
        240       250       260                                    

            300       310       320       330       340       350  
pF1KB8 RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSA
       ..:  :::..: :.: : .::. .: .:.    .  .  .   .:  . :.:::...::.
NP_444 KQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFGNSS
      270       280       290       300       310        320       

            360       370       380       390       400       410  
pF1KB8 ANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKIS
       .:::::.:.. .::. :. ::                                       
NP_444 VNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQN
       330       340       350       360       370       380       

>>NP_001138228 (OMIM: 607449) neuropeptide FF receptor 2  (423 aa)
 initn: 638 init1: 402 opt: 490  Z-score: 528.2  bits: 106.8 E(85289): 1.1e-22
Smith-Waterman score: 618; 33.2% identity (60.3% similar) in 355 aa overlap (27-373:30-351)

                  10        20        30        40        50       
pF1KB8    MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVF
                                    : :  . :.   ::.  :   ..: .:  .:
NP_001 MFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYV-NYYLHQPQVAAIFIISYFLIF
               10        20        30         40        50         

        60        70        80        90       100       110       
pF1KB8 VVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHA
        . ..:::.::. : ::.::.:::: ::.::...:.::  .:.: .:: .:  .: ::..
NP_001 FLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNT
      60        70        80        90       100       110         

       120       130       140       150       160       170       
pF1KB8 LCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMV
       .::.   .:..::...:.::  ::.::.  . .:.  : : . :   :. ::.....:: 
NP_001 MCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMS
     120       130       140       150       160       170         

       180       190       200               210       220         
pF1KB8 PQAAVMECSSVLPELANRTRLFSV--------CDERWADDLYPKIYHSCFFIVTYLAPLG
       :.:....   :  :   :.:: :         : : : .. . ::: . .:   :::::.
NP_001 PSAVMLH---VQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLS
     180          190       200       210       220       230      

     230       240       250       260       270       280         
pF1KB8 LMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQ
       :... : .:  .:.   .: :     ..:.  :                           
NP_001 LIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS---------------------------
        240       250       260                                    

     290       300       310       320       330       340         
pF1KB8 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
        : ..:  :::..: :.: : .::. .: .:.    .  .  .   .:  . :.:::...
NP_001 -RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFG
      270       280       290       300       310        320       

     350       360       370       380       390       400         
pF1KB8 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSIS
       ::..:::::.:.. .::. :. ::                                    
NP_001 NSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQEST
       330       340       350       360       370       380       

>>NP_004876 (OMIM: 607449) neuropeptide FF receptor 2 is  (522 aa)
 initn: 583 init1: 402 opt: 490  Z-score: 527.1  bits: 106.9 E(85289): 1.3e-22
Smith-Waterman score: 618; 33.2% identity (60.3% similar) in 355 aa overlap (27-373:129-450)

                   10        20        30        40        50      
pF1KB8     MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAV
                                     : :  . :.   ::.  :   ..: .:  .
NP_004 ERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYV-NYYLHQPQVAAIFIISYFLI
      100       110       120       130        140       150       

         60        70        80        90       100       110      
pF1KB8 FVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGH
       : . ..:::.::. : ::.::.:::: ::.::...:.::  .:.: .:: .:  .: ::.
NP_004 FFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGN
       160       170       180       190       200       210       

        120       130       140       150       160       170      
pF1KB8 ALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIM
       ..::.   .:..::...:.::  ::.::.  . .:.  : : . :   :. ::.....::
NP_004 TMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIM
       220       230       240       250       260       270       

        180       190       200               210       220        
pF1KB8 VPQAAVMECSSVLPELANRTRLFSV--------CDERWADDLYPKIYHSCFFIVTYLAPL
        :.:....   :  :   :.:: :         : : : .. . ::: . .:   :::::
NP_004 SPSAVMLH---VQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPL
       280          290       300       310       320       330    

      230       240       250       260       270       280        
pF1KB8 GLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVK
       .:... : .:  .:.   .: :     ..:.  :                          
NP_004 SLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS--------------------------
          340       350       360                                  

      290       300       310       320       330       340        
pF1KB8 QMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVY
         : ..:  :::..: :.: : .::. .: .:.    .  .  .   .:  . :.:::..
NP_004 --RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAF
        370       380       390       400       410        420     

      350       360       370       380       390       400        
pF1KB8 ANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSI
       .::..:::::.:.. .::. :. ::                                   
NP_004 GNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQES
         430       440       450       460       470       480     




425 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:17:47 2016 done: Fri Nov  4 10:17:49 2016
 Total Scan time:  7.340 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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