Result of FASTA (omim) for pF1KB7266
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7266, 344 aa
  1>>>pF1KB7266 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6912+/-0.000397; mu= 13.8733+/- 0.024
 mean_var=80.2834+/-17.254, 0's: 0 Z-trim(113.3): 57  B-trim: 1101 in 2/47
 Lambda= 0.143140
 statistics sampled from 22590 (22645) to 22590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.266), width:  16
 Scan time:  5.500

The best scores are:                                      opt bits E(85289)
NP_062559 (OMIM: 609226) WD repeat domain phosphoi ( 344) 2361 497.4 1.8e-140
XP_005256434 (OMIM: 609226) PREDICTED: WD repeat d ( 310) 1771 375.6  8e-104
XP_016880352 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 1541 328.0 1.2e-89
XP_016880351 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 1541 328.0 1.2e-89
NP_001025067 (OMIM: 300526,300894) WD repeat domai ( 360)  858 187.1 5.1e-47
NP_009006 (OMIM: 300526,300894) WD repeat domain p ( 361)  858 187.1 5.2e-47
NP_001028691 (OMIM: 609225) WD repeat domain phosp ( 425)  438 100.4 7.6e-21
NP_057087 (OMIM: 609225) WD repeat domain phosphoi ( 436)  438 100.4 7.7e-21
NP_060453 (OMIM: 609224) WD repeat domain phosphoi ( 446)  429 98.5 2.9e-20
NP_001028690 (OMIM: 609225) WD repeat domain phosp ( 443)  388 90.1   1e-17
NP_056425 (OMIM: 609225) WD repeat domain phosphoi ( 454)  388 90.1   1e-17
NP_001307701 (OMIM: 609224) WD repeat domain phosp ( 364)  382 88.8   2e-17
NP_001028692 (OMIM: 609225) WD repeat domain phosp ( 384)  377 87.8 4.3e-17
XP_016880297 (OMIM: 609224) PREDICTED: WD repeat d ( 318)  335 79.0 1.5e-14
XP_016867441 (OMIM: 609225) PREDICTED: WD repeat d ( 299)  318 75.5 1.6e-13
NP_001265228 (OMIM: 609225) WD repeat domain phosp ( 310)  318 75.5 1.7e-13
XP_006715748 (OMIM: 609225) PREDICTED: WD repeat d ( 310)  318 75.5 1.7e-13
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212)  145 39.7   0.007
XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-c ( 270)  146 40.0  0.0074


>>NP_062559 (OMIM: 609226) WD repeat domain phosphoinosi  (344 aa)
 initn: 2361 init1: 2361 opt: 2361  Z-score: 2642.8  bits: 497.4 E(85289): 1.8e-140
Smith-Waterman score: 2361; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344)

               10        20        30        40        50        60
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
              250       260       270       280       290       300

              310       320       330       340    
pF1KB7 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
       ::::::::::::::::::::::::::::::::::::::::::::
NP_062 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
              310       320       330       340    

>>XP_005256434 (OMIM: 609226) PREDICTED: WD repeat domai  (310 aa)
 initn: 1771 init1: 1771 opt: 1771  Z-score: 1985.0  bits: 375.6 E(85289): 8e-104
Smith-Waterman score: 2040; 90.1% identity (90.1% similar) in 344 aa overlap (1-344:1-310)

               10        20        30        40        50        60
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_005 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQ-------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB7 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
                            :::::::::::::::::::::::::::::::::::::::
XP_005 ---------------------VMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
                             50        60        70        80      

              130       140       150       160       170       180
pF1KB7 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
         90       100       110       120       130       140      

              190       200       210       220       230       240
pF1KB7 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
        150       160       170       180       190       200      

              250       260       270       280       290       300
pF1KB7 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
        210       220       230       240       250       260      

              310       320       330       340    
pF1KB7 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
       ::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
        270       280       290       300       310

>>XP_016880352 (OMIM: 609226) PREDICTED: WD repeat domai  (226 aa)
 initn: 1541 init1: 1541 opt: 1541  Z-score: 1730.3  bits: 328.0 E(85289): 1.2e-89
Smith-Waterman score: 1541; 100.0% identity (100.0% similar) in 226 aa overlap (119-344:1-226)

       90       100       110       120       130       140        
pF1KB7 KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLC
                                     ::::::::::::::::::::::::::::::
XP_016                               MIKVFTFTHNPHQLHVFETCYNPKGLCVLC
                                             10        20        30

      150       160       170       180       190       200        
pF1KB7 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KB7 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
              100       110       120       130       140       150

      270       280       290       300       310       320        
pF1KB7 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
              160       170       180       190       200       210

      330       340    
pF1KB7 IRDVYAQFLEMTDDKL
       ::::::::::::::::
XP_016 IRDVYAQFLEMTDDKL
              220      

>>XP_016880351 (OMIM: 609226) PREDICTED: WD repeat domai  (226 aa)
 initn: 1541 init1: 1541 opt: 1541  Z-score: 1730.3  bits: 328.0 E(85289): 1.2e-89
Smith-Waterman score: 1541; 100.0% identity (100.0% similar) in 226 aa overlap (119-344:1-226)

       90       100       110       120       130       140        
pF1KB7 KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLC
                                     ::::::::::::::::::::::::::::::
XP_016                               MIKVFTFTHNPHQLHVFETCYNPKGLCVLC
                                             10        20        30

      150       160       170       180       190       200        
pF1KB7 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KB7 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
              100       110       120       130       140       150

      270       280       290       300       310       320        
pF1KB7 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
              160       170       180       190       200       210

      330       340    
pF1KB7 IRDVYAQFLEMTDDKL
       ::::::::::::::::
XP_016 IRDVYAQFLEMTDDKL
              220      

>>NP_001025067 (OMIM: 300526,300894) WD repeat domain ph  (360 aa)
 initn: 731 init1: 359 opt: 858  Z-score: 965.0  bits: 187.1 E(85289): 5.1e-47
Smith-Waterman score: 1101; 47.9% identity (75.5% similar) in 351 aa overlap (12-342:8-357)

               10        20        30        40        50          
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM
                  :.    ::::..:: :.::.: :.::..:: :: . .  . :..: :::
NP_001     MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
                   10        20        30        40        50      

      60        70        80              90       100       110   
pF1KB7 LFRCNYLALVGGGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV
       : : : :::::::..::.   .:.::::       :.: :.:. :.  : .:..:.:.::
NP_001 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV
         60        70        80        90       100       110      

           120       130       140       150       160       170   
pF1KB7 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS
       .:: . : :..:  ::..:  :.:  :::::: :::. ...::.::: . : .:::::::
NP_001 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS
        120       130       140       150       160       170      

                180       190       200       210       220        
pF1KB7 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS
       : ::     :  : ::.. ..:..::  :: .:.::.::::::.:::.: . . :::::.
NP_001 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT
         180       190       200       210       220       230     

      230       240       250       260       270           280    
pF1KB7 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW
       . :..:::::..:.:..:.:::.::::::: .: . :..:.:: ..    .. .: .:.:
NP_001 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW
         240       250       260       270       280       290     

          290       300           310       320       330       340
pF1KB7 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT
       :...: ::. : :::::: .     :.:::::.::...:..:.: :.: :...  .:.. 
NP_001 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC
         300       310       320       330       340       350     

            
pF1KB7 DDKL 
       ::   
NP_001 DDDDF
         360

>>NP_009006 (OMIM: 300526,300894) WD repeat domain phosp  (361 aa)
 initn: 836 init1: 359 opt: 858  Z-score: 965.0  bits: 187.1 E(85289): 5.2e-47
Smith-Waterman score: 1092; 47.7% identity (75.3% similar) in 352 aa overlap (12-342:8-358)

               10        20        30        40        50          
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM
                  :.    ::::..:: :.::.: :.::..:: :: . .  . :..: :::
NP_009     MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
                   10        20        30        40        50      

      60        70         80              90       100       110  
pF1KB7 LFRCNYLALVGGGKKPKYPP-NKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRI
       : : : :::::::..::.   . :.::::       :.: :.:. :.  : .:..:.:.:
NP_009 LHRSNLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKI
         60        70        80        90       100       110      

            120       130       140       150       160       170  
pF1KB7 VVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLA
       :.:: . : :..:  ::..:  :.:  :::::: :::. ...::.::: . : .::::::
NP_009 VIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLA
        120       130       140       150       160       170      

                 180       190       200       210       220       
pF1KB7 STEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG
       :: ::     :  : ::.. ..:..::  :: .:.::.::::::.:::.: . . :::::
NP_009 ST-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRG
         180       190       200       210       220       230     

       230       240       250       260       270           280   
pF1KB7 SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSK
       .. :..:::::..:.:..:.:::.::::::: .: . :..:.:: ..    .. .: .:.
NP_009 TDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQ
         240       250       260       270       280       290     

           290       300           310       320       330         
pF1KB7 WSFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEM
       ::...: ::. : :::::: .     :.:::::.::...:..:.: :.: :...  .:..
NP_009 WSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDI
         300       310       320       330       340       350     

     340     
pF1KB7 TDDKL 
        ::   
NP_009 CDDDDF
         360 

>>NP_001028691 (OMIM: 609225) WD repeat domain phosphoin  (425 aa)
 initn: 376 init1: 276 opt: 438  Z-score: 495.2  bits: 100.4 E(85289): 7.6e-21
Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349)

                10         20        30        40         50       
pF1KB7  MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH
                 : : ::.:.::::.  .: : ..:.. .. . . . :.  :  .   :  
NP_001 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL
       :: ::  . .:.:.  : :.    :. .    :   . .  .:. . :::: :.:..: :
NP_001 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
               70             80        90       100       110     

        120       130           140       150       160        170 
pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL
       .  .    . :: ....:.    ::  :: :::.:  :..:  ::.::. : :.::. : 
NP_001 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT
             120       130       140       150       160       170 

             180       190       200       210       220       230 
pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA
        . .   . ::::.. :. .:.. .::..::::::::.::.:.   :. . :.::: .  
NP_001 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
              180       190       200       210       220       230

              240       250       260                   270        
pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP-
          : . :..:. .. .::.  :::::  :  :..                .::.:.:: 
NP_001 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
              240       250       260       270       280       290

          280       290        300          310       320          
pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC
          ..:..  .:.  ..:  :   ::...:    :  ...  :::  : . ..:.  :::
NP_001 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC
              300       310       320       330        340         

      330       340                                                
pF1KB7 IRDVYAQFLEMTDDKL                                            
                                                                   
NP_001 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASAL
     350       360       370       380       390       400         

>>NP_057087 (OMIM: 609225) WD repeat domain phosphoinosi  (436 aa)
 initn: 376 init1: 276 opt: 438  Z-score: 495.1  bits: 100.4 E(85289): 7.7e-21
Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349)

                10         20        30        40         50       
pF1KB7  MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH
                 : : ::.:.::::.  .: : ..:.. .. . . . :.  :  .   :  
NP_057 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL
       :: ::  . .:.:.  : :.    :. .    :   . .  .:. . :::: :.:..: :
NP_057 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
               70             80        90       100       110     

        120       130           140       150       160        170 
pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL
       .  .    . :: ....:.    ::  :: :::.:  :..:  ::.::. : :.::. : 
NP_057 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT
             120       130       140       150       160       170 

             180       190       200       210       220       230 
pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA
        . .   . ::::.. :. .:.. .::..::::::::.::.:.   :. . :.::: .  
NP_057 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
              180       190       200       210       220       230

              240       250       260                   270        
pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP-
          : . :..:. .. .::.  :::::  :  :..                .::.:.:: 
NP_057 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
              240       250       260       270       280       290

          280       290        300          310       320          
pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC
          ..:..  .:.  ..:  :   ::...:    :  ...  :::  : . ..:.  :::
NP_057 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC
              300       310       320       330        340         

      330       340                                                
pF1KB7 IRDVYAQFLEMTDDKL                                            
                                                                   
NP_057 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVG
     350       360       370       380       390       400         

>>NP_060453 (OMIM: 609224) WD repeat domain phosphoinosi  (446 aa)
 initn: 279 init1: 250 opt: 429  Z-score: 484.9  bits: 98.5 E(85289): 2.9e-20
Smith-Waterman score: 451; 29.9% identity (61.4% similar) in 345 aa overlap (18-329:22-352)

                   10        20        30        40        50      
pF1KB7     MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGG---
                            ::::   .: : . :.....   :.  :. . ..:.   
NP_060 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFS---LSSVEQLDQVHGSNEI
               10        20        30        40           50       

              60        70        80        90       100       110 
pF1KB7 --VGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDR
         :  :: ::  . ...:.  :     : .. ..   :   . .  .:... ...: :.:
NP_060 PDVYIVERLFSSSLVVVVSHTK-----PRQMNVYHFKKGTEICNYSYSSNILSIRLNRQR
        60        70             80        90       100       110  

             120       130           140       150       160       
pF1KB7 IVVVLDSMIKVFTFTHNPHQLHVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHV
       ..: :.  :    . :: .......:      :: :::.:  : .:: ::.::. : :..
NP_060 LLVCLEESI----YIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEI
            120           130       140       150       160        

        170       180       190       200       210       220      
pF1KB7 QLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRR
        : : ... :    : ::::.:. :..: .:...:.::::::.::.:.. .:. . :.::
NP_060 VLYD-GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRR
      170        180       190       200       210       220       

         230       240       250       260                   270   
pF1KB7 G-SQAANIYCINFNQDASLICVSSDHGTVHIFAAED--PKRNKQSS----------LASA
       : .. ..:  . :..:....:.::.  :::::  :.   .: .. :          .:..
NP_060 GMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAAT
       230       240       250       260       270       280       

           280           290        300          310       320     
pF1KB7 SFLPKYFSSKW----SFSKFQVP-SGSPCICAFGT---EPNAVIAICADGSYYKFLFNPK
       ..::   :.      .:.  ..  ::.  ::...:    :  ..:  ..:  : . ..:.
NP_060 NYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVA-SSSGHLYMYNLDPQ
       290       300       310       320       330        340      

           330       340                                           
pF1KB7 --GECIRDVYAQFLEMTDDKL                                       
         :::.                                                      
NP_060 DGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGAL
        350       360       370       380       390       400      

>>NP_001028690 (OMIM: 609225) WD repeat domain phosphoin  (443 aa)
 initn: 343 init1: 276 opt: 388  Z-score: 439.2  bits: 90.1 E(85289): 1e-17
Smith-Waterman score: 443; 30.7% identity (56.5% similar) in 368 aa overlap (10-328:11-367)

                10         20                          30        40
pF1KB7  MNLLPCNPHGNG-LLYAGFNQDHG------------------CFACGMENGFRVYNTDP
                 : : ::.:.::::.                    .: : ..:.. .. . 
NP_001 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
               10        20        30        40        50        60

                50         60        70        80        90        
pF1KB7 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF
       . . :.  :  .   :  :: ::  . .:.:.  : :.    :. .    :   . .  .
NP_001 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY
               70        80        90            100       110     

      100       110       120       130           140       150    
pF1KB7 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS
       :. . :::: :.:..: :.  .    . :: ....:.    ::  :: :::.:  :..: 
NP_001 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC
         120       130           140       150       160       170 

          160        170       180       190       200       210   
pF1KB7 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF
        ::.::. : :.::. :  . .   . ::::.. :. .:.. .::..::::::::.::.:
NP_001 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF
             180       190        200       210       220       230

           220       230        240       250       260            
pF1KB7 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS---
       .   :. . :.::: .     : . :..:. .. .::.  :::::  :  :..       
NP_001 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT
              240       250       260       270       280       290

              270           280       290        300          310  
pF1KB7 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAIC
                .::.:.::    ..:..  .:.  ..:  :   ::...:    :  ...  
NP_001 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-
              300       310       320       330       340          

            320         330       340                              
pF1KB7 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL                          
       :::  : . ..:.  :::                                          
NP_001 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYT
     350       360       370       380       390       400         




344 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:28:50 2016 done: Fri Nov  4 06:28:51 2016
 Total Scan time:  5.500 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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