Result of FASTA (omim) for pF1KB7177
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7177, 482 aa
  1>>>pF1KB7177 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7901+/-0.00039; mu= 8.8778+/- 0.024
 mean_var=190.1599+/-38.718, 0's: 0 Z-trim(119.2): 137  B-trim: 462 in 1/55
 Lambda= 0.093007
 statistics sampled from 32844 (32984) to 32844 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.387), width:  16
 Scan time:  8.940

The best scores are:                                      opt bits E(85289)
NP_055971 (OMIM: 607675) REST corepressor 1 [Homo  ( 485) 3141 433.8  5e-121
NP_775858 (OMIM: 616019) REST corepressor 2 [Homo  ( 523) 1458 208.0 5.1e-53
XP_005273989 (OMIM: 616019) PREDICTED: REST corepr ( 477) 1187 171.6 4.2e-42
NP_001070729 (OMIM: 600848) nuclear receptor corep (2458)  327 56.9 7.5e-07
NP_001193583 (OMIM: 600848) nuclear receptor corep (2504)  327 56.9 7.6e-07
NP_006303 (OMIM: 600848) nuclear receptor corepres (2514)  327 56.9 7.6e-07
NP_001177367 (OMIM: 600849) nuclear receptor corep ( 914)  318 55.3 8.4e-07
NP_001177369 (OMIM: 600849) nuclear receptor corep (2337)  318 55.7 1.7e-06
XP_011522388 (OMIM: 600849) PREDICTED: nuclear rec (2337)  318 55.7 1.7e-06
NP_006302 (OMIM: 600849) nuclear receptor corepres (2440)  318 55.7 1.7e-06
XP_016880905 (OMIM: 600849) PREDICTED: nuclear rec (2456)  318 55.7 1.7e-06
XP_006721667 (OMIM: 600849) PREDICTED: nuclear rec (2456)  318 55.7 1.7e-06
XP_016880902 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880899 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880901 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880903 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880898 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_005256929 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880900 (OMIM: 600849) PREDICTED: nuclear rec (2514)  318 55.7 1.8e-06
XP_016880889 (OMIM: 600849) PREDICTED: nuclear rec (2523)  318 55.7 1.8e-06
XP_016880891 (OMIM: 600849) PREDICTED: nuclear rec (2523)  318 55.7 1.8e-06
XP_016880890 (OMIM: 600849) PREDICTED: nuclear rec (2523)  318 55.7 1.8e-06
XP_005256925 (OMIM: 600849) PREDICTED: nuclear rec (2523)  318 55.7 1.8e-06
XP_006721665 (OMIM: 600849) PREDICTED: nuclear rec (2523)  318 55.7 1.8e-06
XP_016880909 (OMIM: 600849) PREDICTED: nuclear rec (2331)  316 55.4   2e-06
XP_016880908 (OMIM: 600849) PREDICTED: nuclear rec (2347)  316 55.4   2e-06
XP_016880907 (OMIM: 600849) PREDICTED: nuclear rec (2404)  316 55.4 2.1e-06
XP_011522387 (OMIM: 600849) PREDICTED: nuclear rec (2405)  316 55.4 2.1e-06
XP_005256932 (OMIM: 600849) PREDICTED: nuclear rec (2448)  316 55.4 2.1e-06
XP_016880906 (OMIM: 600849) PREDICTED: nuclear rec (2450)  316 55.4 2.1e-06
XP_016880904 (OMIM: 600849) PREDICTED: nuclear rec (2465)  316 55.4 2.1e-06
XP_005256931 (OMIM: 600849) PREDICTED: nuclear rec (2466)  316 55.4 2.1e-06
XP_005256930 (OMIM: 600849) PREDICTED: nuclear rec (2508)  316 55.4 2.1e-06
XP_006721666 (OMIM: 600849) PREDICTED: nuclear rec (2511)  316 55.4 2.1e-06
XP_016880895 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_016880892 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_016880896 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_005256928 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_016880893 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_016880897 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_016880894 (OMIM: 600849) PREDICTED: nuclear rec (2515)  316 55.4 2.1e-06
XP_011522386 (OMIM: 600849) PREDICTED: nuclear rec (2523)  316 55.4 2.1e-06
XP_016880885 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_016880886 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_016880887 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_011522385 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_016880888 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_005256923 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06
XP_006721664 (OMIM: 600849) PREDICTED: nuclear rec (2524)  316 55.4 2.1e-06


>>NP_055971 (OMIM: 607675) REST corepressor 1 [Homo sapi  (485 aa)
 initn: 3141 init1: 3141 opt: 3141  Z-score: 2293.8  bits: 433.8 E(85289): 5e-121
Smith-Waterman score: 3141; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:4-485)

                  10        20        30        40        50       
pF1KB7    MVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB7 SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB7 TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB7 HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB7 ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KB7 KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
              430       440       450       460       470       480

       480  
pF1KB7 YASAS
       :::::
NP_055 YASAS
            

>>NP_775858 (OMIM: 616019) REST corepressor 2 [Homo sapi  (523 aa)
 initn: 1309 init1: 726 opt: 1458  Z-score: 1072.9  bits: 208.0 E(85289): 5.1e-53
Smith-Waterman score: 1458; 54.3% identity (76.8% similar) in 435 aa overlap (57-476:3-425)

         30        40        50        60           70        80   
pF1KB7 ASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQ---NKSLAAAAPNGNSSSNS
                                     :.   :. :.   ..: : ..:::.     
NP_775                             MPSVMEKPSAGSGILSRSRAKTVPNGG-----
                                           10        20            

            90       100        110       120       130       140  
pF1KB7 WEEGSSGSSSDEEHGGGGM-RVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLS
        .  :  .::.:::.  .: ::: .::::.:.  : . :: :. ..  ::::::::. .:
NP_775 -QPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSN-KELKGMLVWSPNHCVS
         30        40        50        60         70        80     

            150       160       170       180       190       200  
pF1KB7 EAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQ
       .::::.:::.::::::::.:::::::.::::..::::::: :::::::::::::::::::
NP_775 DAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQ
          90       100       110       120       130       140     

            210       220       230       240       250        260 
pF1KB7 AFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQK-REREESEDEL
       ::.:::: :.::::::::: : ::::.::::::::..::::::.::.   :. .:. :::
NP_775 AFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDEL
         150       160       170       180       190       200     

             270       280         290        300          310     
pF1KB7 EEANGNNPIDIEVDQNKESKKEVP--PTETVPQV-KKEKHSTQAKN---RAKRKPPKGMF
       ::. :.   . : :    ... .:  : .. :   ::: . .: ..   :..:.:::::.
NP_775 EEGRGGVS-EGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTRRRPPKGMY
         210        220       230       240       250       260    

         320       330       340       350       360       370     
pF1KB7 LSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEV
       :: : . :::..   :. .:: :: .:.:.:::.:..:::::.:.. :.:::.: : ::.
NP_775 LSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEA
          270       280       290       300       310       320    

         380       390       400       410       420       430     
pF1KB7 IQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQ
         : :.::::.::::::::::.::.:: ::..:::::...:::.:::.::::::..::::
NP_775 NTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQ
          330       340       350       360       370       380    

         440       450       460           470       480           
pF1KB7 EWEAEHGKEETNGPSNQKPVKSPDNSIKMP----EEEDEAPVLDVRYASAS         
       :::::    . ..:.   :..    .  .:    ::.::. . .:               
NP_775 EWEAE----QDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPP
              390       400       410       420       430       440

NP_775 PPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHS
              450       460       470       480       490       500

>>XP_005273989 (OMIM: 616019) PREDICTED: REST corepresso  (477 aa)
 initn: 1144 init1: 709 opt: 1187  Z-score: 876.9  bits: 171.6 E(85289): 4.2e-42
Smith-Waterman score: 1187; 54.3% identity (75.8% similar) in 359 aa overlap (57-404:3-353)

         30        40        50        60           70        80   
pF1KB7 ASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQ---NKSLAAAAPNGNSSSNS
                                     :.   :. :.   ..: : ..:::.     
XP_005                             MPSVMEKPSAGSGILSRSRAKTVPNGG-----
                                           10        20            

            90       100        110       120       130       140  
pF1KB7 WEEGSSGSSSDEEHGGGGM-RVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLS
        .  :  .::.:::.  .: ::: .::::.:.  : . :: :. ..  ::::::::. .:
XP_005 -QPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSN-KELKGMLVWSPNHCVS
         30        40        50        60         70        80     

            150       160       170       180       190       200  
pF1KB7 EAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQ
       .::::.:::.::::::::.:::::::.::::..::::::: :::::::::::::::::::
XP_005 DAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQ
          90       100       110       120       130       140     

            210       220       230       240       250        260 
pF1KB7 AFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQK-REREESEDEL
       ::.:::: :.::::::::: : ::::.::::::::..::::::.::.   :. .:. :::
XP_005 AFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDEL
         150       160       170       180       190       200     

             270       280         290        300          310     
pF1KB7 EEANGNNPIDIEVDQNKESKKEVP--PTETVPQV-KKEKHSTQAKN---RAKRKPPKGMF
       ::. :.   . : :    ... .:  : .. :   ::: . .: ..   :..:.:::::.
XP_005 EEGRGGVS-EGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTRRRPPKGMY
         210        220       230       240       250       260    

         320       330       340       350       360       370     
pF1KB7 LSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEV
       :: : . :::..   :. .:: :: .:.:.:::.:..:::::.:.. :.:::.: : ::.
XP_005 LSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEA
          270       280       290       300       310       320    

         380       390       400       410       420       430     
pF1KB7 IQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQ
         : :.::::.:::::::.    :   .:                               
XP_005 NTKFNSRWTTDEQLLAVQGPDYIGLHVRAPISAPCATTPSTSHLAVPATPAAEATFAHGS
          330       340       350       360       370       380    

>>NP_001070729 (OMIM: 600848) nuclear receptor corepress  (2458 aa)
 initn: 194 init1: 194 opt: 327  Z-score: 244.0  bits: 56.9 E(85289): 7.5e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:431-702)

             170       180       190       200       210       220 
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
                                     :. ..:  :.. :  : :.:  : ..:  :
NP_001 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
              410       420       430       440       450       460

             230       240         250       260       270         
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
       ..:  : .::  ::...  :.. :  :.  ........... .. . ..:.   . :  .
NP_001 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
              470       480       490       500       510       520

        280       290       300       310       320       330      
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
       .::..::.   :  :.:...:..     . :    .:   ..... : ..  :: .   :
NP_001 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
              530       540          550       560       570       

        340       350       360       370       380       390      
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
       .       . :.. :  ... :.  . .. .  ..: :     ..::: ::.  : ... 
NP_001 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
            580       590       600       610            620       

        400       410       420       430       440       450      
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
       ..::...::. ..:.:.: : :::. ::..: :.::.::. . .  ::..   ...: :.
NP_001 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
       630       640       650       660       670       680       

         460       470       480                                   
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS                                 
        . ...   :  :::                                             
NP_001 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN
       690       700       710       720       730       740       

>>NP_001193583 (OMIM: 600848) nuclear receptor corepress  (2504 aa)
 initn: 194 init1: 194 opt: 327  Z-score: 243.9  bits: 56.9 E(85289): 7.6e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:431-702)

             170       180       190       200       210       220 
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
                                     :. ..:  :.. :  : :.:  : ..:  :
NP_001 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
              410       420       430       440       450       460

             230       240         250       260       270         
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
       ..:  : .::  ::...  :.. :  :.  ........... .. . ..:.   . :  .
NP_001 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
              470       480       490       500       510       520

        280       290       300       310       320       330      
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
       .::..::.   :  :.:...:..     . :    .:   ..... : ..  :: .   :
NP_001 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
              530       540          550       560       570       

        340       350       360       370       380       390      
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
       .       . :.. :  ... :.  . .. .  ..: :     ..::: ::.  : ... 
NP_001 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
            580       590       600       610            620       

        400       410       420       430       440       450      
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
       ..::...::. ..:.:.: : :::. ::..: :.::.::. . .  ::..   ...: :.
NP_001 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
       630       640       650       660       670       680       

         460       470       480                                   
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS                                 
        . ...   :  :::                                             
NP_001 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN
       690       700       710       720       730       740       

>>NP_006303 (OMIM: 600848) nuclear receptor corepressor   (2514 aa)
 initn: 194 init1: 194 opt: 327  Z-score: 243.9  bits: 56.9 E(85289): 7.6e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:432-703)

             170       180       190       200       210       220 
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
                                     :. ..:  :.. :  : :.:  : ..:  :
NP_006 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
             410       420       430       440       450       460 

             230       240         250       260       270         
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
       ..:  : .::  ::...  :.. :  :.  ........... .. . ..:.   . :  .
NP_006 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
             470       480       490       500       510       520 

        280       290       300       310       320       330      
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
       .::..::.   :  :.:...:..     . :    .:   ..... : ..  :: .   :
NP_006 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
             530       540          550       560       570        

        340       350       360       370       380       390      
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
       .       . :.. :  ... :.  . .. .  ..: :     ..::: ::.  : ... 
NP_006 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
      580            590       600       610            620        

        400       410       420       430       440       450      
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
       ..::...::. ..:.:.: : :::. ::..: :.::.::. . .  ::..   ...: :.
NP_006 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
      630       640       650       660       670       680        

         460       470       480                                   
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS                                 
        . ...   :  :::                                             
NP_006 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT
      690       700       710       720       730       740        

>>NP_001177367 (OMIM: 600849) nuclear receptor corepress  (914 aa)
 initn: 271 init1: 184 opt: 318  Z-score: 243.1  bits: 55.3 E(85289): 8.4e-07
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:327-604)

       160       170       180       190       200       210       
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
                                     : . :: ..: .:.. :  : :.:  : ..
NP_001 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
        300       310       320       330       340       350      

       220       230       240            250       260       270  
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
       :  ::. . : .::  ::...  ... :.     .:.:.  :  .:...:: . ..    
NP_001 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
        360       370       380       390       400       410      

            280       290       300       310       320       330  
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
       :  ...: ::.        . : ::.... ... : :       ..:  .:.  .  .:.
NP_001 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
          420              430       440       450       460       

            340       350       360       370       380        390 
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
       .  :.      :.  .    . . .:  :.    . :   :   .  . .::: ::. .:
NP_001 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
       470       480       490       500       510       520       

             400       410       420       430       440       450 
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
        ... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::.    : .. .  : .
NP_001 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
       530       540       550       560       570           580   

                460       470       480                            
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS                          
       .. :   .:  ....  :.::                                       
NP_001 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
           590       600       610       620       630       640   

>>NP_001177369 (OMIM: 600849) nuclear receptor corepress  (2337 aa)
 initn: 355 init1: 184 opt: 318  Z-score: 237.8  bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)

       160       170       180       190       200       210       
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
                                     : . :: ..: .:.. :  : :.:  : ..
NP_001 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
         410       420       430       440       450       460     

       220       230       240            250       260       270  
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
       :  ::. . : .::  ::...  ... :.     .:.:.  :  .:...:: . ..    
NP_001 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
         470       480       490       500       510       520     

            280       290       300       310       320       330  
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
       :  ...: ::.        . : ::.... ... : :       ..:  .:.  .  .:.
NP_001 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
           530              540       550       560       570      

            340       350       360       370       380        390 
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
       .  :.      :.  .    . . .:  :.    . :   :   .  . .::: ::. .:
NP_001 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
        580       590       600       610       620       630      

             400       410       420       430       440       450 
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
        ... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::.    : .. .  : .
NP_001 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
        640       650       660       670       680           690  

                460       470       480                            
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS                          
       .. :   .:  ....  :.::                                       
NP_001 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
            700       710       720       730       740       750  

>>XP_011522388 (OMIM: 600849) PREDICTED: nuclear recepto  (2337 aa)
 initn: 355 init1: 184 opt: 318  Z-score: 237.8  bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)

       160       170       180       190       200       210       
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
                                     : . :: ..: .:.. :  : :.:  : ..
XP_011 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
         410       420       430       440       450       460     

       220       230       240            250       260       270  
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
       :  ::. . : .::  ::...  ... :.     .:.:.  :  .:...:: . ..    
XP_011 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
         470       480       490       500       510       520     

            280       290       300       310       320       330  
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
       :  ...: ::.        . : ::.... ... : :       ..:  .:.  .  .:.
XP_011 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
           530              540       550       560       570      

            340       350       360       370       380        390 
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
       .  :.      :.  .    . . .:  :.    . :   :   .  . .::: ::. .:
XP_011 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
        580       590       600       610       620       630      

             400       410       420       430       440       450 
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
        ... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::.    : .. .  : .
XP_011 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
        640       650       660       670       680           690  

                460       470       480                            
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS                          
       .. :   .:  ....  :.::                                       
XP_011 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
            700       710       720       730       740       750  

>>NP_006302 (OMIM: 600849) nuclear receptor corepressor   (2440 aa)
 initn: 355 init1: 184 opt: 318  Z-score: 237.5  bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)

       160       170       180       190       200       210       
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
                                     : . :: ..: .:.. :  : :.:  : ..
NP_006 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
         410       420       430       440       450       460     

       220       230       240            250       260       270  
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
       :  ::. . : .::  ::...  ... :.     .:.:.  :  .:...:: . ..    
NP_006 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
         470       480       490       500       510       520     

            280       290       300       310       320       330  
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
       :  ...: ::.        . : ::.... ... : :       ..:  .:.  .  .:.
NP_006 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
           530              540       550       560       570      

            340       350       360       370       380        390 
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
       .  :.      :.  .    . . .:  :.    . :   :   .  . .::: ::. .:
NP_006 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
        580       590       600       610       620       630      

             400       410       420       430       440       450 
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
        ... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::.    : .. .  : .
NP_006 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
        640       650       660       670       680           690  

                460       470       480                            
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS                          
       .. :   .:  ....  :.::                                       
NP_006 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVE
            700       710       720       730       740       750  




482 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 05:38:10 2016 done: Fri Nov  4 05:38:11 2016
 Total Scan time:  8.940 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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