Result of FASTA (omim) for pF1KB7139
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7139, 333 aa
  1>>>pF1KB7139 333 - 333 aa - 333 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7042+/-0.000286; mu= 10.8131+/- 0.018
 mean_var=111.1419+/-22.221, 0's: 0 Z-trim(121.4): 47  B-trim: 281 in 1/53
 Lambda= 0.121656
 statistics sampled from 37853 (37900) to 37853 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.444), width:  16
 Scan time:  8.190

The best scores are:                                      opt bits E(85289)
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 2274 409.1 6.5e-114
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 2274 409.1 6.5e-114
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 2274 409.1 6.5e-114
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382)  995 184.7 2.7e-46
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435)  989 183.7 6.3e-46
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap  ( 435)  989 183.7 6.3e-46
NP_859054 (OMIM: 108770,121013,612474,614049) gap  ( 358)  935 174.2 3.8e-43
NP_005257 (OMIM: 108770,121013,612474,614049) gap  ( 358)  935 174.2 3.8e-43
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358)  935 174.2 3.8e-43
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358)  935 174.2 3.8e-43
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515)  887 165.8 1.8e-40
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427)  881 164.7 3.1e-40
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433)  881 164.7 3.2e-40
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433)  881 164.7 3.2e-40
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543)  882 165.0 3.4e-40
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226)  487 95.4 1.2e-19
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226)  487 95.4 1.2e-19
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270)  477 93.7 4.8e-19
NP_076872 (OMIM: 133200,220290,603324,612644) gap  ( 270)  477 93.7 4.8e-19
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261)  464 91.4 2.3e-18
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261)  464 91.4 2.3e-18
NP_065168 (OMIM: 608803,608804,613206,613480) gap  ( 439)  449 88.9 2.1e-17
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap  ( 266)  441 87.4 3.8e-17
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266)  441 87.4 3.8e-17
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283)  439 87.0 5.1e-17
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  439 87.0 5.1e-17
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  439 87.0 5.1e-17
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283)  439 87.0 5.1e-17
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396)  438 87.0 7.5e-17
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396)  438 87.0 7.5e-17
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396)  438 87.0 7.5e-17
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396)  438 87.0 7.5e-17
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321)  428 85.1 2.1e-16
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273)  425 84.6 2.7e-16
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273)  425 84.6 2.7e-16
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223)  419 83.5 4.8e-16
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223)  419 83.5 4.8e-16
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294)  387 77.9 2.9e-14
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279)  322 66.5 7.6e-11
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270)  293 61.4 2.5e-09
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370)  286 60.3 7.6e-09


>>NP_002051 (OMIM: 121012) gap junction alpha-4 protein   (333 aa)
 initn: 2274 init1: 2274 opt: 2274  Z-score: 2166.1  bits: 409.1 E(85289): 6.5e-114
Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
              250       260       270       280       290       300

              310       320       330   
pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV
       :::::::::::::::::: ::::::::::::::
NP_002 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
              310       320       330   

>>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al  (333 aa)
 initn: 2274 init1: 2274 opt: 2274  Z-score: 2166.1  bits: 409.1 E(85289): 6.5e-114
Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
              250       260       270       280       290       300

              310       320       330   
pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV
       :::::::::::::::::: ::::::::::::::
XP_005 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
              310       320       330   

>>XP_016856532 (OMIM: 121012) PREDICTED: gap junction al  (333 aa)
 initn: 2274 init1: 2274 opt: 2274  Z-score: 2166.1  bits: 409.1 E(85289): 6.5e-114
Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
              250       260       270       280       290       300

              310       320       330   
pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV
       :::::::::::::::::: ::::::::::::::
XP_016 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
              310       320       330   

>>NP_000156 (OMIM: 104100,121014,133200,164200,186100,21  (382 aa)
 initn: 1039 init1: 967 opt: 995  Z-score: 952.1  bits: 184.7 E(85289): 2.7e-46
Smith-Waterman score: 1023; 49.1% identity (73.9% similar) in 322 aa overlap (1-298:1-317)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
NP_000 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::..  .  
NP_000 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
        .:.  :  .: .  : .. : :....::.:. ::. :.: ::..:..::  :: .::..
NP_000 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
       .  :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... .    :.
NP_000 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
              190       200       210       220       230          

              250         260               270                    
pF1KB7 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
       . :    . : ..::.  .:  :   : . :.     :..  .: :::            
NP_000 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
        240       250       260       270       280       290      

        280       290       300       310       320       330      
pF1KB7 -CPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV   
        : .::  ..::::::: ..:.                                      
NP_000 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
        300        310       320       330       340       350     

>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p  (435 aa)
 initn: 1064 init1: 603 opt: 989  Z-score: 945.5  bits: 183.7 E(85289): 6.3e-46
Smith-Waterman score: 1020; 46.8% identity (67.2% similar) in 372 aa overlap (1-328:1-359)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: :::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . :  ..
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES
               70        80        90       100       110          

              130       140        150       160       170         
pF1KB7 PQVERALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGW
       :. .      :  . . :  .: ::.:. :::. ::: ... :...:.::. ::. :::.
NP_068 PSPK------EPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGF
     120             130       140       150       160       170   

     180       190       200       210       220       230         
pF1KB7 TMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRG
        ..:.. :.: :::  ::::.::::::::::::::.:.  ::.::.::. ::  . :..:
NP_068 ELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQG
           180       190       200       210       220       230   

     240                250       260              270             
pF1KB7 MRARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP-
       . .: : ::         ::    :: : .  . :  :      :.::.     :..:: 
NP_068 VTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPP
           240       250       260       270       280       290   

                         280          290       300       310      
pF1KB7 ------------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNG
                            :::   :  .:::::: ..:..     :: .   :  . 
NP_068 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAAST
           300       310       320       330            340        

        320       330                                              
pF1KB7 QKSPSRPSSSASKKQYV                                           
         .:: : .:.:                                                
NP_068 PAAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQP
      350        360       370       380       390       400       

>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc  (435 aa)
 initn: 1064 init1: 603 opt: 989  Z-score: 945.5  bits: 183.7 E(85289): 6.3e-46
Smith-Waterman score: 1020; 46.8% identity (67.2% similar) in 372 aa overlap (1-328:1-359)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: :::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . :  ..
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES
               70        80        90       100       110          

              130       140        150       160       170         
pF1KB7 PQVERALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGW
       :. .      :  . . :  .: ::.:. :::. ::: ... :...:.::. ::. :::.
XP_011 PSPK------EPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGF
     120             130       140       150       160       170   

     180       190       200       210       220       230         
pF1KB7 TMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRG
        ..:.. :.: :::  ::::.::::::::::::::.:.  ::.::.::. ::  . :..:
XP_011 ELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQG
           180       190       200       210       220       230   

     240                250       260              270             
pF1KB7 MRARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP-
       . .: : ::         ::    :: : .  . :  :      :.::.     :..:: 
XP_011 VTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPP
           240       250       260       270       280       290   

                         280          290       300       310      
pF1KB7 ------------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNG
                            :::   :  .:::::: ..:..     :: .   :  . 
XP_011 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAAST
           300       310       320       330            340        

        320       330                                              
pF1KB7 QKSPSRPSSSASKKQYV                                           
         .:: : .:.:                                                
XP_011 PAAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQP
      350        360       370       380       390       400       

>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 944 init1: 579 opt: 935  Z-score: 895.6  bits: 174.2 E(85289): 3.8e-43
Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::::::::::::::::..:::::.:::.::...  : .:. . .:.: ::  .. 
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG
               70        80        90       100       110          

               130       140         150       160       170       
pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY
         . :  .:    . :..:  :.:  :. ..:.:..::: :.: ....:.::. ::. .:
NP_859 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY
     120           130       140       150       160       170     

       180       190       200       210       220       230       
pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-
       :  .  . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: ::  . . 
NP_859 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR
         180       190       200       210       220       230     

        240           250         260       270       280       290
pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN
       .: .. ::     : . :. :   :  :  :   :   . .::..     ...  .:.::
NP_859 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN
         240       250       260          270       280       290  

              300       310       320       330                    
pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV                 
         ::.::.  .. . :       . ::: :  :.                          
NP_859 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA
            300       310       320        330       340       350 

NP_859 RSDDLSV
              

>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 944 init1: 579 opt: 935  Z-score: 895.6  bits: 174.2 E(85289): 3.8e-43
Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: :::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::::::::::::::::..:::::.:::.::...  : .:. . .:.: ::  .. 
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG
               70        80        90       100       110          

               130       140         150       160       170       
pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY
         . :  .:    . :..:  :.:  :. ..:.:..::: :.: ....:.::. ::. .:
NP_005 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY
     120           130       140       150       160       170     

       180       190       200       210       220       230       
pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-
       :  .  . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: ::  . . 
NP_005 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR
         180       190       200       210       220       230     

        240           250         260       270       280       290
pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN
       .: .. ::     : . :. :   :  :  :   :   . .::..     ...  .:.::
NP_005 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN
         240       250       260          270       280       290  

              300       310       320       330                    
pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV                 
         ::.::.  .. . :       . ::: :  :.                          
NP_005 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA
            300       310       320        330       340       350 

NP_005 RSDDLSV
              

>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 944 init1: 579 opt: 935  Z-score: 895.6  bits: 174.2 E(85289): 3.8e-43
Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::::::::::::::::..:::::.:::.::...  : .:. . .:.: ::  .. 
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG
               70        80        90       100       110          

               130       140         150       160       170       
pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY
         . :  .:    . :..:  :.:  :. ..:.:..::: :.: ....:.::. ::. .:
XP_016 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY
     120           130       140       150       160       170     

       180       190       200       210       220       230       
pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-
       :  .  . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: ::  . . 
XP_016 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR
         180       190       200       210       220       230     

        240           250         260       270       280       290
pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN
       .: .. ::     : . :. :   :  :  :   :   . .::..     ...  .:.::
XP_016 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN
         240       250       260          270       280       290  

              300       310       320       330                    
pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV                 
         ::.::.  .. . :       . ::: :  :.                          
XP_016 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA
            300       310       320        330       340       350 

XP_016 RSDDLSV
              

>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 944 init1: 579 opt: 935  Z-score: 895.6  bits: 174.2 E(85289): 3.8e-43
Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325)

               10        20        30        40        50        60
pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
       ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
       : :::::::::::::::::::..:::::.:::.::...  : .:. . .:.: ::  .. 
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG
               70        80        90       100       110          

               130       140         150       160       170       
pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY
         . :  .:    . :..:  :.:  :. ..:.:..::: :.: ....:.::. ::. .:
XP_005 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY
     120           130       140       150       160       170     

       180       190       200       210       220       230       
pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-
       :  .  . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: ::  . . 
XP_005 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR
         180       190       200       210       220       230     

        240           250         260       270       280       290
pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN
       .: .. ::     : . :. :   :  :  :   :   . .::..     ...  .:.::
XP_005 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN
         240       250       260          270       280       290  

              300       310       320       330                    
pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV                 
         ::.::.  .. . :       . ::: :  :.                          
XP_005 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA
            300       310       320        330       340       350 

XP_005 RSDDLSV
              




333 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 05:12:35 2016 done: Fri Nov  4 05:12:36 2016
 Total Scan time:  8.190 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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