Result of FASTA (omim) for pF1KE1069
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1069, 177 aa
  1>>>pF1KE1069 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1170+/-0.000296; mu= 8.9682+/- 0.019
 mean_var=75.7194+/-15.020, 0's: 0 Z-trim(118.7): 30  B-trim: 1189 in 1/52
 Lambda= 0.147391
 statistics sampled from 31863 (31893) to 31863 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.374), width:  16
 Scan time:  5.410

The best scores are:                                      opt bits E(85289)
NP_758955 (OMIM: 612211) tumor suppressor candidat ( 177) 1130 248.8 3.3e-66
XP_016878377 (OMIM: 128200,614386) PREDICTED: prol ( 340)  339 80.7 2.6e-15
NP_660282 (OMIM: 128200,614386) proline-rich trans ( 340)  339 80.7 2.6e-15
XP_016878378 (OMIM: 128200,614386) PREDICTED: prol ( 340)  331 79.0 8.4e-15
XP_016878376 (OMIM: 128200,614386) PREDICTED: prol ( 346)  331 79.0 8.5e-15
XP_011544018 (OMIM: 128200,614386) PREDICTED: prol ( 394)  331 79.0 9.5e-15
XP_011544017 (OMIM: 128200,614386) PREDICTED: prol ( 394)  331 79.0 9.5e-15
NP_001243371 (OMIM: 128200,614386) proline-rich tr ( 394)  331 79.0 9.5e-15
NP_001243372 (OMIM: 128200,614386) proline-rich tr ( 299)  165 43.7 0.00031


>>NP_758955 (OMIM: 612211) tumor suppressor candidate 5   (177 aa)
 initn: 1130 init1: 1130 opt: 1130  Z-score: 1309.6  bits: 248.8 E(85289): 3.3e-66
Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)

               10        20        30        40        50        60
pF1KE1 MAHPVQSEFPSAQEPGSAAFLDLPEMEILLTKAENKDDKTLNLSKTLSGPLDLEQNSQGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 MAHPVQSEFPSAQEPGSAAFLDLPEMEILLTKAENKDDKTLNLSKTLSGPLDLEQNSQGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEAPRDYLILAVVACFCPVWPLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 PFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEAPRDYLILAVVACFCPVWPLN
               70        80        90       100       110       120

              130       140       150       160       170       
pF1KE1 LIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGIVIIMVAVTVNFTVQKK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 LIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGIVIIMVAVTVNFTVQKK
              130       140       150       160       170       

>>XP_016878377 (OMIM: 128200,614386) PREDICTED: proline-  (340 aa)
 initn: 350 init1: 325 opt: 339  Z-score: 396.0  bits: 80.7 E(85289): 2.6e-15
Smith-Waterman score: 339; 45.7% identity (78.1% similar) in 105 aa overlap (75-176:236-340)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170       
pF1KE1 VIIMVAVTVNFTVQKK
       .::... ..:. : : 
XP_016 LIIIASCVINLGVYK 
         330       340 

>>NP_660282 (OMIM: 128200,614386) proline-rich transmemb  (340 aa)
 initn: 350 init1: 325 opt: 339  Z-score: 396.0  bits: 80.7 E(85289): 2.6e-15
Smith-Waterman score: 339; 45.7% identity (78.1% similar) in 105 aa overlap (75-176:236-340)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
NP_660 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
NP_660 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170       
pF1KE1 VIIMVAVTVNFTVQKK
       .::... ..:. : : 
NP_660 LIIIASCVINLGVYK 
         330       340 

>>XP_016878378 (OMIM: 128200,614386) PREDICTED: proline-  (340 aa)
 initn: 342 init1: 317 opt: 331  Z-score: 386.8  bits: 79.0 E(85289): 8.4e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170       
pF1KE1 VIIMVAVTVNFTVQKK
       .::... ..:.     
XP_016 LIIIASCVINLGDAA 
         330       340 

>>XP_016878376 (OMIM: 128200,614386) PREDICTED: proline-  (346 aa)
 initn: 342 init1: 317 opt: 331  Z-score: 386.7  bits: 79.0 E(85289): 8.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170            
pF1KE1 VIIMVAVTVNFTVQKK     
       .::... ..:.          
XP_016 LIIIASCVINLGGCCMSLKHQ
         330       340      

>>XP_011544018 (OMIM: 128200,614386) PREDICTED: proline-  (394 aa)
 initn: 342 init1: 317 opt: 331  Z-score: 385.7  bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
XP_011 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
XP_011 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170                                                   
pF1KE1 VIIMVAVTVNFTVQKK                                            
       .::... ..:.                                                 
XP_011 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
         330       340       350       360       370       380     

>>XP_011544017 (OMIM: 128200,614386) PREDICTED: proline-  (394 aa)
 initn: 342 init1: 317 opt: 331  Z-score: 385.7  bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
XP_011 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
XP_011 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170                                                   
pF1KE1 VIIMVAVTVNFTVQKK                                            
       .::... ..:.                                                 
XP_011 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
         330       340       350       360       370       380     

>>NP_001243371 (OMIM: 128200,614386) proline-rich transm  (394 aa)
 initn: 342 init1: 317 opt: 331  Z-score: 385.7  bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
NP_001 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:::.:.:::.::::.::::.:.::::. .. :.
NP_001 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
         270       280       290       300       310       320     

             170                                                   
pF1KE1 VIIMVAVTVNFTVQKK                                            
       .::... ..:.                                                 
NP_001 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
         330       340       350       360       370       380     

>>NP_001243372 (OMIM: 128200,614386) proline-rich transm  (299 aa)
 initn: 176 init1: 151 opt: 165  Z-score: 196.9  bits: 43.7 E(85289): 0.00031
Smith-Waterman score: 165; 39.7% identity (69.0% similar) in 58 aa overlap (75-129:236-293)

           50        60        70        80        90       100    
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
                                     : ::  . ::. ::  .   ..  :.   :
NP_001 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
         210       220       230       240       250       260     

             110       120       130       140       150       160 
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
       :::.:::...::::.::.:.. .  ..:                                
NP_001 RDYIILAILSCFCPMWPVNIVAFAYAVMVSPMGP                          
         270       280       290                                   




177 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:42:15 2016 done: Fri Nov  4 04:42:16 2016
 Total Scan time:  5.410 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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