Result of FASTA (omim) for pF1KB3955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3955, 454 aa
  1>>>pF1KB3955 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6049+/-0.000389; mu= -6.9197+/- 0.024
 mean_var=291.7638+/-60.998, 0's: 0 Z-trim(121.1): 143  B-trim: 0 in 0/55
 Lambda= 0.075086
 statistics sampled from 37166 (37309) to 37166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.437), width:  16
 Scan time: 10.500

The best scores are:                                      opt bits E(85289)
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 3248 365.2  2e-100
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 1905 219.8 1.3e-56
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 1798 208.2 3.9e-53
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 1797 208.1 4.4e-53
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 1492 175.0 3.5e-43
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 1443 169.7 1.2e-41
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 1371 161.9   3e-39
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 1365 161.3   5e-39
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 1365 161.3   5e-39
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 1139 136.8 1.3e-31
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 1084 130.8 7.2e-30
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 1084 130.8 7.2e-30
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 1084 130.8 7.7e-30
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 1084 130.8 7.7e-30
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 1068 129.1 2.5e-29
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 1007 122.3 1.3e-27
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 1007 122.3 1.3e-27
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354)  441 61.1 5.6e-09
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398)  441 61.1 6.1e-09
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432)  441 61.2 6.5e-09
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225)  434 60.2 6.5e-09
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418)  430 60.0 1.4e-08
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441)  430 60.0 1.5e-08
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450)  430 60.0 1.5e-08
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475)  430 60.0 1.6e-08
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485)  430 60.0 1.6e-08
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485)  430 60.0 1.6e-08
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469)  429 59.9 1.7e-08
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469)  429 59.9 1.7e-08
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469)  429 59.9 1.7e-08
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519)  430 60.0 1.7e-08
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609)  429 60.0 2.1e-08
NP_001129627 (OMIM: 165080) transcriptional regula ( 387)  405 57.2 8.9e-08
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459)  405 57.3   1e-07
NP_891548 (OMIM: 165080) transcriptional regulator ( 479)  405 57.3 1.1e-07
NP_001230357 (OMIM: 165080) transcriptional regula ( 486)  405 57.3 1.1e-07
NP_001129626 (OMIM: 165080) transcriptional regula ( 486)  405 57.3 1.1e-07
NP_001230358 (OMIM: 165080) transcriptional regula ( 363)  393 55.9 2.1e-07
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428)  393 56.0 2.4e-07
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435)  393 56.0 2.4e-07
NP_001317954 (OMIM: 165080) transcriptional regula ( 455)  393 56.0 2.5e-07
NP_004440 (OMIM: 165080) transcriptional regulator ( 462)  393 56.0 2.5e-07
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259)  384 54.8 3.1e-07
NP_001244097 (OMIM: 311040) ETS domain-containing  (  95)  373 53.3 3.2e-07
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238)  382 54.6 3.4e-07
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410)  386 55.2 3.9e-07
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386)  384 54.9 4.3e-07


>>NP_001156619 (OMIM: 600541) ETS translocation variant   (454 aa)
 initn: 3248 init1: 3248 opt: 3248  Z-score: 1924.0  bits: 365.2 E(85289): 2e-100
Smith-Waterman score: 3248; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDSGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGSAASQSFPPPLMIKQEPRDFAYDSGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 REGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHIN
              370       380       390       400       410       420

              430       440       450    
pF1KB3 EEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       ::::::::::::::::::::::::::::::::::
NP_001 EEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
              430       440       450    

>>XP_011513470 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 3234 init1: 1905 opt: 1905  Z-score: 1137.5  bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)

               10        20        30        40        50        60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
              190       200       210       220       230       240

              250       260                              270       
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
       :::::::::::::::::::::::::::                       ::::::::::
XP_011 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
              370       380       390       400       410       420

       400       410       420       430       440       450    
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
              430       440       450       460       470       

>>XP_005249693 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 3234 init1: 1905 opt: 1905  Z-score: 1137.5  bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)

               10        20        30        40        50        60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
              190       200       210       220       230       240

              250       260                              270       
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
       :::::::::::::::::::::::::::                       ::::::::::
XP_005 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
              370       380       390       400       410       420

       400       410       420       430       440       450    
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
              430       440       450       460       470       

>>NP_004947 (OMIM: 600541) ETS translocation variant 1 i  (477 aa)
 initn: 3234 init1: 1905 opt: 1905  Z-score: 1137.5  bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)

               10        20        30        40        50        60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_004 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
              190       200       210       220       230       240

              250       260                              270       
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
       :::::::::::::::::::::::::::                       ::::::::::
NP_004 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
              370       380       390       400       410       420

       400       410       420       430       440       450    
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
              430       440       450       460       470       

>>XP_005249692 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 3234 init1: 1905 opt: 1905  Z-score: 1137.5  bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)

               10        20        30        40        50        60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
              190       200       210       220       230       240

              250       260                              270       
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
       :::::::::::::::::::::::::::                       ::::::::::
XP_005 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
              370       380       390       400       410       420

       400       410       420       430       440       450    
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
              430       440       450       460       470       

>>XP_011513472 (OMIM: 600541) PREDICTED: ETS translocati  (472 aa)
 initn: 3126 init1: 1797 opt: 1798  Z-score: 1074.9  bits: 208.2 E(85289): 3.9e-53
Smith-Waterman score: 3085; 93.4% identity (94.5% similar) in 470 aa overlap (9-454:3-472)

               10         20        30        40        50         
pF1KB3 MDGFYDQQVPYM-VTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLA
               .:.  . .::::::::::::::::::::::::::::::::::::::::::::
XP_011       MSLPFSDLDKSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLA
                     10        20        30        40        50    

      60        70        80        90       100       110         
pF1KB3 EAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLY
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 EAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
           60        70        80        90       100       110    

     120       130       140       150       160       170         
pF1KB3 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSS
          120       130       140       150       160       170    

     180       190       200       210       220       230         
pF1KB3 YPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHN
          180       190       200       210       220       230    

     240       250       260                              270      
pF1KB3 TMVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPR
       ::::::::::::::::::::::::::::                       :::::::::
XP_011 TMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPR
          240       250       260       270       280       290    

        280       290       300       310       320       330      
pF1KB3 QFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
          300       310       320       330       340       350    

        340       350       360       370       380       390      
pF1KB3 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
          360       370       380       390       400       410    

        400       410       420       430       440       450    
pF1KB3 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
          420       430       440       450       460       470  

>>XP_011513469 (OMIM: 600541) PREDICTED: ETS translocati  (491 aa)
 initn: 3126 init1: 1797 opt: 1797  Z-score: 1074.1  bits: 208.1 E(85289): 4.4e-53
Smith-Waterman score: 3084; 94.8% identity (95.0% similar) in 462 aa overlap (16-454:30-491)

                             10        20        30        40      
pF1KB3               MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEEL
                                    :::::::::::::::::::::::::::::::
XP_011 MSGRGDGGQQQLLHSKFLAGFVCHIEKNESQRGRNCNEKPTNVRKRKFINRDLAHDSEEL
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KB3 FQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_011 FQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQE
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KB3 QPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFP
              130       140       150       160       170       180

        170       180       190       200       210       220      
pF1KB3 AHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQG
              190       200       210       220       230       240

        230       240       250       260                          
pF1KB3 FKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS-------------------
       :::::::::::::::::::::::::::::::::::::::::                   
XP_011 FKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHP
              250       260       270       280       290       300

           270       280       290       300       310       320   
pF1KB3 ----GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLD
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLD
              310       320       330       340       350       360

           330       340       350       360       370       380   
pF1KB3 DPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVA
              370       380       390       400       410       420

           390       400       410       420       430       440   
pF1KB3 GERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCC
              430       440       450       460       470       480

           450    
pF1KB3 NPHPYNEGYVY
       :::::::::::
XP_011 NPHPYNEGYVY
              490 

>>NP_001156622 (OMIM: 600541) ETS translocation variant   (437 aa)
 initn: 2821 init1: 1492 opt: 1492  Z-score: 896.2  bits: 175.0 E(85289): 3.5e-43
Smith-Waterman score: 2779; 94.2% identity (94.5% similar) in 417 aa overlap (61-454:21-437)

               40        50        60        70        80        90
pF1KB3 KRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
                                     ::::::::::::::::::::::::::::::
NP_001           MLQDLSASVFFPPCSQHRTLAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
                         10        20        30        40        50

              100       110       120       130       140       150
pF1KB3 EPHSPCSEIGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
               60        70        80        90       100       110

              160       170       180       190       200       210
pF1KB3 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
              120       130       140       150       160       170

              220       230       240       250       260          
pF1KB3 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVP
              180       190       200       210       220       230

                           270       280       290       300       
pF1KB3 --------------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
                           ::::::::::::::::::::::::::::::::::::::::
NP_001 SCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
              240       250       260       270       280       290

       310       320       330       340       350       360       
pF1KB3 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
              300       310       320       330       340       350

       370       380       390       400       410       420       
pF1KB3 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
              360       370       380       390       400       410

       430       440       450    
pF1KB3 SHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::
NP_001 SHFDESMAYMPEGGCCNPHPYNEGYVY
              420       430       

>>NP_001156624 (OMIM: 600541) ETS translocation variant   (374 aa)
 initn: 2348 init1: 1343 opt: 1443  Z-score: 868.5  bits: 169.7 E(85289): 1.2e-41
Smith-Waterman score: 2184; 79.1% identity (79.4% similar) in 417 aa overlap (61-454:21-374)

               40        50        60        70        80        90
pF1KB3 KRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
                                     ::::::::::::::::::::::::::::::
NP_001           MLQDLSASVFFPPCSQHRTLAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
                         10        20        30        40        50

              100       110       120       130       140       150
pF1KB3 EPHSPCSEIGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
       :::::::::.:::::::::::::::::::::                             
NP_001 EPHSPCSEISSACSQEQPFKFSYGEKCLYNV-----------------------------
               60        70        80                              

              160       170       180       190       200       210
pF1KB3 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
                                         ::::::::::::::::::::::::::
NP_001 ----------------------------------RFRRQLSEPCNSFPPLPTMPREGRPM
                                                90       100       

              220       230       240       250       260          
pF1KB3 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVP
       110       120       130       140       150       160       

                           270       280       290       300       
pF1KB3 --------------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
                           ::::::::::::::::::::::::::::::::::::::::
NP_001 SCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
       170       180       190       200       210       220       

       310       320       330       340       350       360       
pF1KB3 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
       230       240       250       260       270       280       

       370       380       390       400       410       420       
pF1KB3 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
       290       300       310       320       330       340       

       430       440       450    
pF1KB3 SHFDESMAYMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::::::::::
NP_001 SHFDESMAYMPEGGCCNPHPYNEGYVY
       350       360       370    

>>NP_001156623 (OMIM: 600541) ETS translocation variant   (419 aa)
 initn: 2692 init1: 1363 opt: 1371  Z-score: 825.7  bits: 161.9 E(85289): 3e-39
Smith-Waterman score: 2658; 92.4% identity (93.2% similar) in 409 aa overlap (70-454:11-419)

      40        50        60        70         80        90        
pF1KB3 AHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESL-AFHGLPLKIKKEPHSPCSE
                                     : :  : ..: :::::::::::::::::::
NP_001                     MLQDLSASVFFPPCSQHRTLVAFHGLPLKIKKEPHSPCSE
                                   10        20        30        40

      100       110       120       130       140       150        
pF1KB3 IGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHT
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHT
               50        60        70        80        90       100

      160       170       180       190       200       210        
pF1KB3 PKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEP
              110       120       130       140       150       160

      220       230       240       250       260                  
pF1KB3 NIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 NIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMR
              170       180       190       200       210       220

                   270       280       290       300       310     
pF1KB3 ------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLW
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLW
              230       240       250       260       270       280

         320       330       340       350       360       370     
pF1KB3 QFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYE
              290       300       310       320       330       340

         380       390       400       410       420       430     
pF1KB3 KGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMA
              350       360       370       380       390       400

         440       450    
pF1KB3 YMPEGGCCNPHPYNEGYVY
       :::::::::::::::::::
NP_001 YMPEGGCCNPHPYNEGYVY
              410         




454 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:45:24 2016 done: Fri Nov  4 02:45:26 2016
 Total Scan time: 10.500 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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