Result of FASTA (omim) for pF1KB3938
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3938, 442 aa
  1>>>pF1KB3938 442 - 442 aa - 442 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4368+/-0.000371; mu= 13.8810+/- 0.024
 mean_var=144.9312+/-32.343, 0's: 0 Z-trim(117.7): 558  B-trim: 3077 in 2/51
 Lambda= 0.106535
 statistics sampled from 29152 (29853) to 29152 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.35), width:  16
 Scan time:  9.780

The best scores are:                                      opt bits E(85289)
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 3008 474.1 3.2e-133
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 3008 474.1 3.2e-133
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 3008 474.2 3.7e-133
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 2687 424.7 2.3e-118
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 1611 259.4 1.4e-68
NP_001243212 (OMIM: 131243,157300,616367) endothel ( 202)  865 144.4 2.7e-34
NP_001159527 (OMIM: 131243,157300,616367) endothel ( 318)  817 137.2 6.1e-32
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390)  652 111.9   3e-24
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384)  627 108.1 4.3e-23
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399)  590 102.4 2.3e-21
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  402 73.5 1.2e-12
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381)  401 73.3 1.2e-12
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  401 73.3 1.2e-12
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  401 73.3 1.2e-12
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380)  391 71.8 3.5e-12
XP_011534148 (OMIM: 162341) PREDICTED: neuromedin- ( 283)  381 70.1 8.3e-12
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415)  382 70.4 9.7e-12
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613)  383 70.8 1.1e-11
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370)  376 69.5 1.7e-11
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366)  373 69.0 2.3e-11
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  372 68.9 2.7e-11
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  372 68.9 2.7e-11
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384)  372 68.9 2.7e-11
XP_016866390 (OMIM: 162341) PREDICTED: neuromedin- ( 301)  367 68.0 3.9e-11
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  366 67.9   5e-11
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  366 67.9   5e-11
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375)  366 67.9   5e-11
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  366 67.9   5e-11
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  366 67.9   5e-11
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375)  366 67.9   5e-11
NP_444264 (OMIM: 607449) neuropeptide FF receptor  ( 420)  365 67.8   6e-11
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423)  365 67.8   6e-11
NP_004876 (OMIM: 607449) neuropeptide FF receptor  ( 522)  365 67.9   7e-11
NP_001311237 (OMIM: 162341) neuromedin-B receptor  ( 242)  353 65.7 1.5e-10
XP_016866391 (OMIM: 162341) PREDICTED: neuromedin- ( 242)  353 65.7 1.5e-10
NP_001311236 (OMIM: 162341) neuromedin-B receptor  ( 242)  353 65.7 1.5e-10
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380)  355 66.3 1.6e-10
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409)  355 66.3 1.7e-10
NP_057624 (OMIM: 605569) probable G-protein couple ( 423)  350 65.5   3e-10
NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328)  342 64.2 5.9e-10
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  340 64.0 8.7e-10
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321)  335 63.1 1.2e-09
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391)  330 62.4 2.4e-09
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369)  329 62.2 2.5e-09
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393)  315 60.1 1.2e-08
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348)  312 59.6 1.5e-08
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384)  312 59.7 1.6e-08
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384)  312 59.7 1.6e-08
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398)  307 58.9 2.8e-08
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269)  304 58.3 2.9e-08


>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel  (442 aa)
 initn: 3008 init1: 3008 opt: 3008  Z-score: 2512.7  bits: 474.1 E(85289): 3.2e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:1-442)

               10        20        30        40        50        60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_000 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
              370       380       390       400       410       420

              430       440  
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
       ::::::::::::::::::::::
NP_000 LKFKANDHGYDNFRSSNKYSSS
              430       440  

>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot  (442 aa)
 initn: 3008 init1: 3008 opt: 3008  Z-score: 2512.7  bits: 474.1 E(85289): 3.2e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:1-442)

               10        20        30        40        50        60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
              370       380       390       400       410       420

              430       440  
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
       ::::::::::::::::::::::
NP_001 LKFKANDHGYDNFRSSNKYSSS
              430       440  

>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot  (532 aa)
 initn: 3008 init1: 3008 opt: 3008  Z-score: 2511.7  bits: 474.2 E(85289): 3.7e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:91-532)

                                             10        20        30
pF1KB3                               MQPPPSLCGRALVALVLACGLSRIWGEERG
                                     ::::::::::::::::::::::::::::::
NP_001 PFVALHLVCQIREALKLRSGHRTPSGAGSSMQPPPSLCGRALVALVLACGLSRIWGEERG
               70        80        90       100       110       120

               40        50        60        70        80        90
pF1KB3 FPPDRATPLLQTAEMMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPC
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPC
              130       140       150       160       170       180

              100       110       120       130       140       150
pF1KB3 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
              190       200       210       220       230       240

              160       170       180       190       200       210
pF1KB3 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
              250       260       270       280       290       300

              220       230       240       250       260       270
pF1KB3 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYK
              310       320       330       340       350       360

              280       290       300       310       320       330
pF1KB3 TAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVL
              370       380       390       400       410       420

              340       350       360       370       380       390
pF1KB3 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
              430       440       450       460       470       480

              400       410       420       430       440  
pF1KB3 KRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
              490       500       510       520       530  

>>NP_003982 (OMIM: 131244,277580,600155,600501) endothel  (436 aa)
 initn: 2711 init1: 2687 opt: 2687  Z-score: 2246.1  bits: 424.7 E(85289): 2.3e-118
Smith-Waterman score: 2687; 99.5% identity (100.0% similar) in 399 aa overlap (1-399:1-399)

               10        20        30        40        50        60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_003 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
       ::::::::::::::::::::::::::::::::::::::.                     
NP_003 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGT
              370       380       390       400       410       420

              430       440  
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
                             
NP_003 VNQNPTMWPERKSNNN      
              430            

>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re  (427 aa)
 initn: 988 init1: 579 opt: 1611  Z-score: 1352.5  bits: 259.4 E(85289): 1.4e-68
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (90-440:69-425)

      60        70        80        90       100       110         
pF1KB3 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
                                     :    .:  .:::::::.:: .:..:..::
NP_001 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
       40        50        60        70        80        90        

     120       130       140       150       160            170    
pF1KB3 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
       .:::::::.::::::::: ::::::::::...:::.::::.::::  :::     :. .:
NP_001 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
      100       110       120       130       140       150        

          180       190       200       210       220       230    
pF1KB3 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
       :: ::.::.:::::::.:::::.:::::::::::..:::.:  ::.::: ::..: .::.
NP_001 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
      160       170       180       190       200       210        

          240       250       260       270       280       290    
pF1KB3 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
       :::::: .. ..:.:   . :.:. ..:  ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
      220       230       240         250       260       270      

          300        310       320       330       340       350   
pF1KB3 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
       ::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. 
NP_001 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
        280       290       300       310       320       330      

           360       370       380       390       400        410  
pF1KB3 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
       : ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::     
NP_001 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
        340       350       360       370       380       390      

            420       430        440  
pF1KB3 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
       :.  . . ...: .:..  :  :::.: :  
NP_001 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
        400       410       420       

>>NP_001243212 (OMIM: 131243,157300,616367) endothelin-1  (202 aa)
 initn: 579 init1: 579 opt: 865  Z-score: 736.8  bits: 144.4 E(85289): 2.7e-34
Smith-Waterman score: 865; 60.9% identity (84.2% similar) in 202 aa overlap (242-440:1-200)

             220       230       240       250       260       270 
pF1KB3 IGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKT
                                     .. ..:.:   . :.:. ..:  ::.::. 
NP_001                               MVPFEYRGEQHKTCMLNATSK--FMEFYQD
                                             10        20          

             280       290       300        310       320       330
pF1KB3 AKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVL
       .::::::.::::.::. ::.:::::::::: ...: ..:::..::::::::::::::::.
NP_001 VKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVV
       30        40        50        60        70        80        

              340       350       360       370       380       390
pF1KB3 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
       .:::::.::::::::: :.::. : ::::::::::..::::::.:..::::::::::.::
NP_001 IFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVS
       90       100       110       120       130       140        

              400        410       420       430        440  
pF1KB3 KRFKNCFKSCLCCWC-QSFEEKQSLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
       :.:::::.::::: : ::     :.  . . ...: .:..  :  :::.: :  
NP_001 KKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
      150       160       170       180       190       200  

>>NP_001159527 (OMIM: 131243,157300,616367) endothelin-1  (318 aa)
 initn: 916 init1: 579 opt: 817  Z-score: 694.5  bits: 137.2 E(85289): 6.1e-32
Smith-Waterman score: 948; 46.6% identity (61.0% similar) in 354 aa overlap (90-440:69-316)

      60        70        80        90       100       110         
pF1KB3 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
                                     :    .:  .:::::::.:: .:..:..::
NP_001 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KB3 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPF
       .:::::::.::::::::: ::::::::::...:::.::::.:                  
NP_001 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK------------------
      100       110       120       130       140                  

     180       190       200       210       220       230         
pF1KB3 IQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIG
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

     240       250       260       270       280       290         
pF1KB3 FDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCE
                                   ::. .::::::.::::.::. ::.::::::::
NP_001 ----------------------------FYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCE
                                          150       160       170  

     300        310       320       330       340       350        
pF1KB3 MLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRC
       :: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. : :::
NP_001 MLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRC
            180       190       200       210       220       230  

      360       370       380       390       400        410       
pF1KB3 ELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQSLEEK
       :::::::..::::::.:..::::::::::.:::.:::::.::::: : ::     :.  .
NP_001 ELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMN
            240       250       260       270       280       290  

       420       430        440  
pF1KB3 QSCLKFKANDHGYDNF-RSSNKYSSS
        . ...: .:..  :  :::.: :  
NP_001 GTSIQWKNHDQNNHNTDRSSHKDSMN
            300       310        

>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform  (390 aa)
 initn: 666 init1: 376 opt: 652  Z-score: 556.3  bits: 111.9 E(85289): 3e-24
Smith-Waterman score: 652; 31.7% identity (62.4% similar) in 356 aa overlap (63-411:3-349)

             40        50        60        70        80          90
pF1KB3 PDRATPLLQTAEMMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPP--PC
                                     ..::.   :  :   .:: :.       : 
NP_002                             MPSKSLSNLSVTTGANESGSVPEGWERDFLPA
                                           10        20        30  

              100       110       120       130       140       150
pF1KB3 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
       .     . ... .   .  :....:..::  :..:.  :. ::. :::.:..:: :::: 
NP_002 SDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLL
             40        50        60        70        80        90  

              160       170       180       190       200       210
pF1KB3 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
       ..  .:... . . ..: ::   :::.: :: .:::..:..: ::: :::::...   ..
NP_002 LLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQ
            100       110       120       130       140       150  

              220       230       240        250       260         
pF1KB3 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMD-YKGSYLRICLLHPVQKTAFMQFY
         :.   : :. . ::::::.::::::.  ..  ..   .: .  :. .:       ...
NP_002 TSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTD----ELH
            160       170       180       190       200            

     270       280       290       300       310           320     
pF1KB3 KTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQ----RREVAKTV
          ..  .:  :: .:::: ...:  ..  ....  ..    :.: :.    :...:: :
NP_002 PKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIV
      210       220       230       240       250       260        

         330       340       350       360       370       380     
pF1KB3 FCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIA
       . .:  : .::.: :.  . .   ::. ::.    :. ..:   ..  ..  :::.::.:
NP_002 LVFVGCFIFCWFPNHILYMYRSFNYNEIDPS----LGHMIVT-LVARVLSFGNSCVNPFA
      270       280       290           300        310       320   

         390       400       410       420       430       440     
pF1KB3 LYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS   
       :::.:. :.  :.: :::  .:..:.                                  
NP_002 LYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHS
           330       340       350       360       370       380   

>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec  (384 aa)
 initn: 555 init1: 384 opt: 627  Z-score: 535.7  bits: 108.1 E(85289): 4.3e-23
Smith-Waterman score: 627; 32.1% identity (65.9% similar) in 340 aa overlap (102-433:41-371)

              80        90       100       110       120       130 
pF1KB3 PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC
                                     :.  .:  .....:.::: ::..:.   : 
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
               20        30        40        50        60        70

             140       150       160       170       180       190 
pF1KB3 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS
       ::: ::..:.:::::::: ..   :... . ::. : ::   :::.:::: .:::..:..
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
               80        90       100       110       120       130

             200       210       220       230       240       250 
pF1KB3 LCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY
       : ::: :::.:..    :..  .     .. ..::..:..::.:::.  :.  .  ... 
NP_005 LTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTN
              140       150       160       170       180       190

               260       270       280       290       300         
pF1KB3 LRI--CLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQI
         .  :  .: ..    .... :.    :  .. .::.: . .: ... .....  .. .
NP_005 QTFISCAPYPHSNELHPKIHSMAS----FLVFYVIPLSIISVYYYFIAKNLIQSAYNLPV
              200       210           220       230       240      

     310           320       330       340       350       360     
pF1KB3 ALNDHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLL
         : :.:.    :...::::. .: .::.:::: :.  . .   :.. : .   .: :  
NP_005 EGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---MLHF--
        250       260       270       280       290          300   

         370       380       390        400       410       420    
pF1KB3 VLDYIGINMASLNSCINPIALYLVSKRFKNCFKS-CLCCWCQSFEEKQSLEEKQSCL-KF
       : .  .  .:  :::.::.::::.:: :.. :..  :::    . ...:  .. .:. ..
NP_005 VTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSL
             310       320       330       340       350       360 

           430       440      
pF1KB3 KANDHGYDNFRSSNKYSSS    
       :... .  .:             
NP_005 KSTNPSVATFSLINGNICHERYV
             370       380    

>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [  (399 aa)
 initn: 545 init1: 348 opt: 590  Z-score: 504.7  bits: 102.4 E(85289): 2.3e-21
Smith-Waterman score: 590; 32.9% identity (67.4% similar) in 310 aa overlap (106-407:52-350)

          80        90       100       110       120       130     
pF1KB3 RTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNG
                                     ..  ... .::.::. :.....:.: :.. 
NP_001 SSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTV
              30        40        50        60        70        80 

         140       150       160       170       180       190     
pF1KB3 PNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCAL
       :::.:.:::.:::: ..  .:... . ::: : ::   ::.. ::. .:::..:..:  :
NP_001 PNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTIL
              90       100       110       120       130       140 

         200        210       220       230       240         250  
pF1KB3 SIDRYRAVAS-WSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITM--DYKGSYL
       : :::.::..   :  . .. : : :.   .:.::...:.::::  .. :.    :.  .
NP_001 SADRYKAVVKPLERQPSNAILK-TCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTF
             150       160        170       180       190       200

            260       270       280       290       300       310  
pF1KB3 RICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALN
       . :  .::.:  ......       :  .. .::.: . .:.:..  . ..  ..    .
NP_001 ESCTSYPVSKKLLQEIHSLL----CFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQ
              210       220           230       240       250      

                320       330       340        350       360       
pF1KB3 DHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILK-LTLYNQNDPNRCELLSFLLVL
       .: ..    :...:.::. :: .::::::: ::  . . .:  .  ::.  ...  . ..
NP_001 SHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFI--FTIF
        260       270       280       290       300       310      

       370       380       390       400       410       420       
pF1KB3 DYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKAND
       . .   .:  :::.::.::: .:: :.. ::. : : :..                    
NP_001 SRV---LAFSNSCVNPFALYWLSKSFQKHFKAQLFC-CKAERPEPPVADTSLTTLAVMGT
             320       330       340        350       360       370

       430       440                
pF1KB3 HGYDNFRSSNKYSSS              
                                    
NP_001 VPGTGSIQMSEISVTSFTGCSVKQAEDRF
              380       390         




442 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:44:43 2016 done: Fri Nov  4 02:44:44 2016
 Total Scan time:  9.780 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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