Result of FASTA (omim) for pF1KB0497
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0497, 4427 aa
  1>>>pF1KB0497 4427 - 4427 aa - 4427 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2383+/-0.00067; mu= 19.6555+/- 0.042
 mean_var=143.0560+/-29.570, 0's: 0 Z-trim(107.6): 165  B-trim: 476 in 2/56
 Lambda= 0.107231
 statistics sampled from 15457 (15622) to 15457 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.487), E-opt: 0.2 (0.183), width:  16
 Scan time: 28.400

The best scores are:                                      opt bits E(85289)
NP_065928 (OMIM: 603333) dynein heavy chain 2, axo (4427) 29334 4553.1       0
XP_011521969 (OMIM: 603333) PREDICTED: dynein heav (4427) 29334 4553.1       0
XP_011521966 (OMIM: 603333) PREDICTED: dynein heav (4509) 26768 4156.1       0
XP_011521965 (OMIM: 603333) PREDICTED: dynein heav (4509) 26768 4156.1       0
XP_011521970 (OMIM: 603333) PREDICTED: dynein heav (3973) 26259 4077.3       0
XP_011521971 (OMIM: 603333) PREDICTED: dynein heav (3841) 25421 3947.7       0
XP_016879707 (OMIM: 603333) PREDICTED: dynein heav (3844) 25102 3898.3       0
XP_016879708 (OMIM: 603333) PREDICTED: dynein heav (3799) 21620 3359.7       0
XP_011521972 (OMIM: 603333) PREDICTED: dynein heav (3551) 20302 3155.8       0
XP_011521968 (OMIM: 603333) PREDICTED: dynein heav (4446) 14378 2239.4       0
NP_775899 (OMIM: 610063) dynein heavy chain 17, ax (4462) 7652 1198.8       0
XP_011523718 (OMIM: 610063) PREDICTED: dynein heav (4466) 7635 1196.2       0
NP_001363 (OMIM: 603330) dynein heavy chain 9, axo (4486) 7579 1187.6       0
XP_016879781 (OMIM: 603330) PREDICTED: dynein heav (4462) 7077 1109.9       0
XP_011522005 (OMIM: 603330) PREDICTED: dynein heav (4501) 7071 1109.0       0
XP_016879782 (OMIM: 603330) PREDICTED: dynein heav (3795) 6945 1089.4       0
NP_001264044 (OMIM: 603339,611884) dynein heavy ch (4516) 6186 972.1       0
XP_016874450 (OMIM: 605884) PREDICTED: dynein heav (4486) 5736 902.4       0
NP_997320 (OMIM: 605884) dynein heavy chain 10, ax (4471) 5571 876.9       0
XP_005253612 (OMIM: 605884) PREDICTED: dynein heav (4589) 5571 876.9       0
XP_016874451 (OMIM: 605884) PREDICTED: dynein heav (3509) 5544 872.7       0
XP_011536321 (OMIM: 605884) PREDICTED: dynein heav (3536) 5544 872.7       0
XP_011509792 (OMIM: 610061) PREDICTED: dynein heav (3949) 5417 853.0       0
XP_011536319 (OMIM: 605884) PREDICTED: dynein heav (4477) 4994 787.6       0
XP_011536317 (OMIM: 605884) PREDICTED: dynein heav (4526) 4994 787.7       0
XP_011536316 (OMIM: 605884) PREDICTED: dynein heav (4536) 4994 787.7       0
XP_016879783 (OMIM: 603330) PREDICTED: dynein heav (3362) 4971 784.0       0
XP_016880750 (OMIM: 610063) PREDICTED: dynein heav (2244) 4746 749.1 2.7e-214
XP_016878915 (OMIM: 603334) PREDICTED: dynein heav (4032) 4076 645.6 6.9e-183
XP_011536318 (OMIM: 605884) PREDICTED: dynein heav (4526) 3930 623.0 4.7e-176
XP_011512621 (OMIM: 603337) PREDICTED: dynein heav (4671) 3759 596.6 4.5e-168
XP_016873781 (OMIM: 603297) PREDICTED: cytoplasmic (4101) 3757 596.3  5e-168
NP_001368 (OMIM: 603297) cytoplasmic dynein 2 heav (4307) 3757 596.3 5.2e-168
NP_001073932 (OMIM: 603297) cytoplasmic dynein 2 h (4314) 3662 581.6 1.4e-163
XP_011509799 (OMIM: 610061) PREDICTED: dynein heav (2148) 3635 577.2 1.5e-162
XP_016873780 (OMIM: 603297) PREDICTED: cytoplasmic (4237) 3573 567.8 1.9e-159
XP_016874449 (OMIM: 605884) PREDICTED: dynein heav (4494) 3497 556.1 6.9e-156
XP_016878919 (OMIM: 603334) PREDICTED: dynein heav (2095) 3450 548.5 5.9e-154
XP_006718966 (OMIM: 603297) PREDICTED: cytoplasmic (4300) 3412 542.9 6.1e-152
XP_011536322 (OMIM: 605884) PREDICTED: dynein heav (2591) 3373 536.7 2.7e-150
XP_016864673 (OMIM: 603335,608644) PREDICTED: dyne (3071) 3323 529.0 6.5e-148
XP_016864672 (OMIM: 603335,608644) PREDICTED: dyne (3238) 3323 529.0 6.8e-148
XP_016864671 (OMIM: 603335,608644) PREDICTED: dyne (3809) 3323 529.1 7.7e-148
XP_016865816 (OMIM: 603337) PREDICTED: dynein heav (2857) 3265 520.0 3.1e-145
XP_016879784 (OMIM: 603330) PREDICTED: dynein heav (2548) 3253 518.1  1e-144
XP_016864677 (OMIM: 603335,608644) PREDICTED: dyne (2653) 3042 485.5 7.1e-135
XP_016864675 (OMIM: 603335,608644) PREDICTED: dyne (2874) 3042 485.5 7.5e-135
XP_016864674 (OMIM: 603335,608644) PREDICTED: dyne (3023) 3042 485.5 7.8e-135
XP_016864668 (OMIM: 603335,608644) PREDICTED: dyne (4295) 3042 485.7  1e-134
XP_016864667 (OMIM: 603335,608644) PREDICTED: dyne (4295) 3042 485.7  1e-134


>>NP_065928 (OMIM: 603333) dynein heavy chain 2, axonema  (4427 aa)
 initn: 29334 init1: 29334 opt: 29334  Z-score: 24521.5  bits: 4553.1 E(85289):    0
Smith-Waterman score: 29334; 99.9% identity (100.0% similar) in 4427 aa overlap (1-4427:1-4427)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFE
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_065 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB0 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KB0 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KB0 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KB0 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KB0 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KB0 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KB0 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KB0 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
             2470      2480      2490      2500      2510      2520

             2530      2540      2550      2560      2570      2580
pF1KB0 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
             2530      2540      2550      2560      2570      2580

             2590      2600      2610      2620      2630      2640
pF1KB0 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
             2590      2600      2610      2620      2630      2640

             2650      2660      2670      2680      2690      2700
pF1KB0 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
             2650      2660      2670      2680      2690      2700

             2710      2720      2730      2740      2750      2760
pF1KB0 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
             2710      2720      2730      2740      2750      2760

             2770      2780      2790      2800      2810      2820
pF1KB0 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
             2770      2780      2790      2800      2810      2820

             2830      2840      2850      2860      2870      2880
pF1KB0 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
             2830      2840      2850      2860      2870      2880

             2890      2900      2910      2920      2930      2940
pF1KB0 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
             2890      2900      2910      2920      2930      2940

             2950      2960      2970      2980      2990      3000
pF1KB0 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
             2950      2960      2970      2980      2990      3000

             3010      3020      3030      3040      3050      3060
pF1KB0 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
             3010      3020      3030      3040      3050      3060

             3070      3080      3090      3100      3110      3120
pF1KB0 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
             3070      3080      3090      3100      3110      3120

             3130      3140      3150      3160      3170      3180
pF1KB0 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
             3130      3140      3150      3160      3170      3180

             3190      3200      3210      3220      3230      3240
pF1KB0 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
             3190      3200      3210      3220      3230      3240

             3250      3260      3270      3280      3290      3300
pF1KB0 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
             3250      3260      3270      3280      3290      3300

             3310      3320      3330      3340      3350      3360
pF1KB0 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
             3310      3320      3330      3340      3350      3360

             3370      3380      3390      3400      3410      3420
pF1KB0 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
             3370      3380      3390      3400      3410      3420

             3430      3440      3450      3460      3470      3480
pF1KB0 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
             3430      3440      3450      3460      3470      3480

             3490      3500      3510      3520      3530      3540
pF1KB0 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
             3490      3500      3510      3520      3530      3540

             3550      3560      3570      3580      3590      3600
pF1KB0 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
             3550      3560      3570      3580      3590      3600

             3610      3620      3630      3640      3650      3660
pF1KB0 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
             3610      3620      3630      3640      3650      3660

             3670      3680      3690      3700      3710      3720
pF1KB0 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
             3670      3680      3690      3700      3710      3720

             3730      3740      3750      3760      3770      3780
pF1KB0 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
             3730      3740      3750      3760      3770      3780

             3790      3800      3810      3820      3830      3840
pF1KB0 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
             3790      3800      3810      3820      3830      3840

             3850      3860      3870      3880      3890      3900
pF1KB0 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
             3850      3860      3870      3880      3890      3900

             3910      3920      3930      3940      3950      3960
pF1KB0 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
             3910      3920      3930      3940      3950      3960

             3970      3980      3990      4000      4010      4020
pF1KB0 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
             3970      3980      3990      4000      4010      4020

             4030      4040      4050      4060      4070      4080
pF1KB0 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
             4030      4040      4050      4060      4070      4080

             4090      4100      4110      4120      4130      4140
pF1KB0 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
             4090      4100      4110      4120      4130      4140

             4150      4160      4170      4180      4190      4200
pF1KB0 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
             4150      4160      4170      4180      4190      4200

             4210      4220      4230      4240      4250      4260
pF1KB0 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMR
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::::
NP_065 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
             4210      4220      4230      4240      4250      4260

             4270      4280      4290      4300      4310      4320
pF1KB0 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
             4270      4280      4290      4300      4310      4320

             4330      4340      4350      4360      4370      4380
pF1KB0 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
             4330      4340      4350      4360      4370      4380

             4390      4400      4410      4420       
pF1KB0 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
             4390      4400      4410      4420       

>>XP_011521969 (OMIM: 603333) PREDICTED: dynein heavy ch  (4427 aa)
 initn: 29334 init1: 29334 opt: 29334  Z-score: 24521.5  bits: 4553.1 E(85289):    0
Smith-Waterman score: 29334; 99.9% identity (100.0% similar) in 4427 aa overlap (1-4427:1-4427)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFE
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB0 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KB0 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KB0 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KB0 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KB0 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KB0 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KB0 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KB0 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
             2470      2480      2490      2500      2510      2520

             2530      2540      2550      2560      2570      2580
pF1KB0 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
             2530      2540      2550      2560      2570      2580

             2590      2600      2610      2620      2630      2640
pF1KB0 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
             2590      2600      2610      2620      2630      2640

             2650      2660      2670      2680      2690      2700
pF1KB0 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
             2650      2660      2670      2680      2690      2700

             2710      2720      2730      2740      2750      2760
pF1KB0 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
             2710      2720      2730      2740      2750      2760

             2770      2780      2790      2800      2810      2820
pF1KB0 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
             2770      2780      2790      2800      2810      2820

             2830      2840      2850      2860      2870      2880
pF1KB0 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
             2830      2840      2850      2860      2870      2880

             2890      2900      2910      2920      2930      2940
pF1KB0 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
             2890      2900      2910      2920      2930      2940

             2950      2960      2970      2980      2990      3000
pF1KB0 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
             2950      2960      2970      2980      2990      3000

             3010      3020      3030      3040      3050      3060
pF1KB0 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
             3010      3020      3030      3040      3050      3060

             3070      3080      3090      3100      3110      3120
pF1KB0 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
             3070      3080      3090      3100      3110      3120

             3130      3140      3150      3160      3170      3180
pF1KB0 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
             3130      3140      3150      3160      3170      3180

             3190      3200      3210      3220      3230      3240
pF1KB0 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
             3190      3200      3210      3220      3230      3240

             3250      3260      3270      3280      3290      3300
pF1KB0 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
             3250      3260      3270      3280      3290      3300

             3310      3320      3330      3340      3350      3360
pF1KB0 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
             3310      3320      3330      3340      3350      3360

             3370      3380      3390      3400      3410      3420
pF1KB0 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
             3370      3380      3390      3400      3410      3420

             3430      3440      3450      3460      3470      3480
pF1KB0 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
             3430      3440      3450      3460      3470      3480

             3490      3500      3510      3520      3530      3540
pF1KB0 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
             3490      3500      3510      3520      3530      3540

             3550      3560      3570      3580      3590      3600
pF1KB0 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
             3550      3560      3570      3580      3590      3600

             3610      3620      3630      3640      3650      3660
pF1KB0 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
             3610      3620      3630      3640      3650      3660

             3670      3680      3690      3700      3710      3720
pF1KB0 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
             3670      3680      3690      3700      3710      3720

             3730      3740      3750      3760      3770      3780
pF1KB0 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
             3730      3740      3750      3760      3770      3780

             3790      3800      3810      3820      3830      3840
pF1KB0 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
             3790      3800      3810      3820      3830      3840

             3850      3860      3870      3880      3890      3900
pF1KB0 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
             3850      3860      3870      3880      3890      3900

             3910      3920      3930      3940      3950      3960
pF1KB0 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
             3910      3920      3930      3940      3950      3960

             3970      3980      3990      4000      4010      4020
pF1KB0 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
             3970      3980      3990      4000      4010      4020

             4030      4040      4050      4060      4070      4080
pF1KB0 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
             4030      4040      4050      4060      4070      4080

             4090      4100      4110      4120      4130      4140
pF1KB0 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
             4090      4100      4110      4120      4130      4140

             4150      4160      4170      4180      4190      4200
pF1KB0 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
             4150      4160      4170      4180      4190      4200

             4210      4220      4230      4240      4250      4260
pF1KB0 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMR
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::::
XP_011 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
             4210      4220      4230      4240      4250      4260

             4270      4280      4290      4300      4310      4320
pF1KB0 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
             4270      4280      4290      4300      4310      4320

             4330      4340      4350      4360      4370      4380
pF1KB0 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
             4330      4340      4350      4360      4370      4380

             4390      4400      4410      4420       
pF1KB0 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
             4390      4400      4410      4420       

>>XP_011521966 (OMIM: 603333) PREDICTED: dynein heavy ch  (4509 aa)
 initn: 26768 init1: 26768 opt: 26768  Z-score: 22376.0  bits: 4156.1 E(85289):    0
Smith-Waterman score: 28848; 98.1% identity (98.1% similar) in 4459 aa overlap (51-4427:51-4509)

               30        40        50        60        70        80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
                                     ::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
               30        40        50        60        70        80

               90       100       110       120       130       140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
               90       100       110       120       130       140

              150       160       170       180       190       200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
              150       160       170       180       190       200

              210       220       230       240       250       260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
              210       220       230       240       250       260

              270       280       290       300       310       320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
              270       280       290       300       310       320

              330       340       350       360       370       380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
              330       340       350       360       370       380

              390                                                  
pF1KB0 RERLTSLFRK--------------------------------------------------
       ::::::::::                                                  
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
              390       400       410       420       430       440

                                              400       410        
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
                                       ::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
              450       460       470       480       490       500

      420       430       440       450       460       470        
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
              510       520       530       540       550       560

      480       490       500       510       520       530        
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
              570       580       590       600       610       620

      540       550       560       570       580       590        
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
              630       640       650       660       670       680

      600       610       620       630       640       650        
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
              690       700       710       720       730       740

      660       670       680       690       700       710        
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
              750       760       770       780       790       800

      720       730       740       750       760       770        
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
              810       820       830       840       850       860

      780       790       800       810       820       830        
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
              870       880       890       900       910       920

      840       850       860       870       880       890        
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
              930       940       950       960       970       980

      900       910       920       930       940       950        
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
              990      1000      1010      1020      1030      1040

      960       970       980       990      1000      1010        
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
             1050      1060      1070      1080      1090      1100

     1020      1030      1040      1050      1060      1070        
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
             1110      1120      1130      1140      1150      1160

     1080      1090      1100      1110      1120      1130        
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
             1170      1180      1190      1200      1210      1220

     1140      1150      1160      1170      1180      1190        
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
             1230      1240      1250      1260      1270      1280

     1200      1210      1220      1230      1240      1250        
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
             1290      1300      1310      1320      1330      1340

     1260      1270      1280      1290      1300      1310        
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
             1350      1360      1370      1380      1390      1400

     1320      1330      1340      1350      1360      1370        
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
             1410      1420      1430      1440      1450      1460

     1380      1390      1400      1410      1420      1430        
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
             1470      1480      1490      1500      1510      1520

     1440      1450      1460      1470      1480      1490        
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
             1530      1540      1550      1560      1570      1580

     1500      1510      1520      1530      1540      1550        
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
             1590      1600      1610      1620      1630      1640

     1560      1570      1580      1590      1600      1610        
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
             1650      1660      1670      1680      1690      1700

     1620      1630      1640      1650      1660      1670        
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
             1710      1720      1730      1740      1750      1760

     1680      1690      1700      1710      1720      1730        
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
             1770      1780      1790      1800      1810      1820

     1740      1750      1760      1770      1780      1790        
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
             1830      1840      1850      1860      1870      1880

     1800      1810      1820      1830      1840      1850        
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
             1890      1900      1910      1920      1930      1940

     1860      1870      1880      1890      1900      1910        
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
             1950      1960      1970      1980      1990      2000

     1920      1930      1940      1950      1960      1970        
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
             2010      2020      2030      2040      2050      2060

     1980      1990      2000      2010      2020      2030        
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
             2070      2080      2090      2100      2110      2120

     2040      2050      2060      2070      2080      2090        
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
             2130      2140      2150      2160      2170      2180

     2100      2110      2120      2130      2140      2150        
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
             2190      2200      2210      2220      2230      2240

     2160      2170      2180      2190      2200      2210        
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
             2250      2260      2270      2280      2290      2300

     2220      2230      2240      2250      2260      2270        
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
             2310      2320      2330      2340      2350      2360

     2280      2290      2300      2310      2320      2330        
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
             2370      2380      2390      2400      2410      2420

     2340      2350      2360      2370      2380      2390        
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
             2430      2440      2450      2460      2470      2480

     2400      2410      2420      2430      2440      2450        
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
             2490      2500      2510      2520      2530      2540

     2460      2470      2480      2490      2500      2510        
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
             2550      2560      2570      2580      2590      2600

     2520      2530      2540      2550      2560      2570        
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
             2610      2620      2630      2640      2650      2660

     2580      2590      2600      2610      2620      2630        
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
             2670      2680      2690      2700      2710      2720

     2640      2650      2660      2670      2680      2690        
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
             2730      2740      2750      2760      2770      2780

     2700      2710      2720      2730      2740      2750        
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
             2790      2800      2810      2820      2830      2840

     2760      2770      2780      2790      2800      2810        
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
             2850      2860      2870      2880      2890      2900

     2820      2830      2840      2850      2860      2870        
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
             2910      2920      2930      2940      2950      2960

     2880      2890      2900      2910      2920      2930        
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
             2970      2980      2990      3000      3010      3020

     2940      2950      2960      2970      2980      2990        
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
             3030      3040      3050      3060      3070      3080

     3000      3010      3020      3030      3040      3050        
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
             3090      3100      3110      3120      3130      3140

     3060      3070      3080      3090      3100      3110        
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
             3150      3160      3170      3180      3190      3200

     3120      3130      3140      3150      3160      3170        
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
             3210      3220      3230      3240      3250      3260

     3180      3190      3200      3210      3220      3230        
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
             3270      3280      3290      3300      3310      3320

     3240      3250      3260      3270      3280      3290        
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
             3330      3340      3350      3360      3370      3380

     3300      3310      3320      3330      3340      3350        
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
             3390      3400      3410      3420      3430      3440

     3360      3370      3380      3390      3400      3410        
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
             3450      3460      3470      3480      3490      3500

     3420      3430      3440      3450      3460      3470        
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
             3510      3520      3530      3540      3550      3560

     3480      3490      3500      3510      3520      3530        
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
             3570      3580      3590      3600      3610      3620

     3540      3550      3560      3570      3580      3590        
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
             3630      3640      3650      3660      3670      3680

     3600      3610      3620      3630      3640      3650        
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
             3690      3700      3710      3720      3730      3740

     3660      3670      3680      3690      3700      3710        
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
             3750      3760      3770      3780      3790      3800

     3720      3730      3740      3750      3760      3770        
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
             3810      3820      3830      3840      3850      3860

     3780      3790      3800      3810      3820      3830        
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
             3870      3880      3890      3900      3910      3920

     3840      3850      3860      3870      3880      3890        
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
             3930      3940      3950      3960      3970      3980

     3900      3910      3920      3930      3940      3950        
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
             3990      4000      4010      4020      4030      4040

     3960      3970      3980      3990      4000      4010        
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
             4050      4060      4070      4080      4090      4100

     4020      4030      4040      4050      4060      4070        
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
             4110      4120      4130      4140      4150      4160

     4080      4090      4100      4110      4120      4130        
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
             4170      4180      4190      4200      4210      4220

     4140      4150      4160      4170      4180      4190        
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
             4230      4240      4250      4260      4270      4280

     4200      4210      4220      4230      4240      4250        
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
             4290      4300      4310      4320      4330      4340

     4260      4270      4280      4290      4300      4310        
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
             4350      4360      4370      4380      4390      4400

     4320      4330      4340      4350      4360      4370        
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
             4410      4420      4430      4440      4450      4460

     4380      4390      4400      4410      4420       
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
             4470      4480      4490      4500         

>--
 initn: 312 init1: 312 opt: 312  Z-score: 256.7  bits: 63.3 E(85289): 1.5e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
                                                                   
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

>>XP_011521965 (OMIM: 603333) PREDICTED: dynein heavy ch  (4509 aa)
 initn: 26768 init1: 26768 opt: 26768  Z-score: 22376.0  bits: 4156.1 E(85289):    0
Smith-Waterman score: 28848; 98.1% identity (98.1% similar) in 4459 aa overlap (51-4427:51-4509)

               30        40        50        60        70        80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
                                     ::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
               30        40        50        60        70        80

               90       100       110       120       130       140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
               90       100       110       120       130       140

              150       160       170       180       190       200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
              150       160       170       180       190       200

              210       220       230       240       250       260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
              210       220       230       240       250       260

              270       280       290       300       310       320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
              270       280       290       300       310       320

              330       340       350       360       370       380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
              330       340       350       360       370       380

              390                                                  
pF1KB0 RERLTSLFRK--------------------------------------------------
       ::::::::::                                                  
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
              390       400       410       420       430       440

                                              400       410        
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
                                       ::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
              450       460       470       480       490       500

      420       430       440       450       460       470        
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
              510       520       530       540       550       560

      480       490       500       510       520       530        
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
              570       580       590       600       610       620

      540       550       560       570       580       590        
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
              630       640       650       660       670       680

      600       610       620       630       640       650        
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
              690       700       710       720       730       740

      660       670       680       690       700       710        
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
              750       760       770       780       790       800

      720       730       740       750       760       770        
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
              810       820       830       840       850       860

      780       790       800       810       820       830        
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
              870       880       890       900       910       920

      840       850       860       870       880       890        
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
              930       940       950       960       970       980

      900       910       920       930       940       950        
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
              990      1000      1010      1020      1030      1040

      960       970       980       990      1000      1010        
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
             1050      1060      1070      1080      1090      1100

     1020      1030      1040      1050      1060      1070        
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
             1110      1120      1130      1140      1150      1160

     1080      1090      1100      1110      1120      1130        
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
             1170      1180      1190      1200      1210      1220

     1140      1150      1160      1170      1180      1190        
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
             1230      1240      1250      1260      1270      1280

     1200      1210      1220      1230      1240      1250        
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
             1290      1300      1310      1320      1330      1340

     1260      1270      1280      1290      1300      1310        
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
             1350      1360      1370      1380      1390      1400

     1320      1330      1340      1350      1360      1370        
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
             1410      1420      1430      1440      1450      1460

     1380      1390      1400      1410      1420      1430        
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
             1470      1480      1490      1500      1510      1520

     1440      1450      1460      1470      1480      1490        
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
             1530      1540      1550      1560      1570      1580

     1500      1510      1520      1530      1540      1550        
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
             1590      1600      1610      1620      1630      1640

     1560      1570      1580      1590      1600      1610        
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
             1650      1660      1670      1680      1690      1700

     1620      1630      1640      1650      1660      1670        
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
             1710      1720      1730      1740      1750      1760

     1680      1690      1700      1710      1720      1730        
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
             1770      1780      1790      1800      1810      1820

     1740      1750      1760      1770      1780      1790        
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
             1830      1840      1850      1860      1870      1880

     1800      1810      1820      1830      1840      1850        
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
             1890      1900      1910      1920      1930      1940

     1860      1870      1880      1890      1900      1910        
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
             1950      1960      1970      1980      1990      2000

     1920      1930      1940      1950      1960      1970        
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
             2010      2020      2030      2040      2050      2060

     1980      1990      2000      2010      2020      2030        
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
             2070      2080      2090      2100      2110      2120

     2040      2050      2060      2070      2080      2090        
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
             2130      2140      2150      2160      2170      2180

     2100      2110      2120      2130      2140      2150        
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
             2190      2200      2210      2220      2230      2240

     2160      2170      2180      2190      2200      2210        
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
             2250      2260      2270      2280      2290      2300

     2220      2230      2240      2250      2260      2270        
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
             2310      2320      2330      2340      2350      2360

     2280      2290      2300      2310      2320      2330        
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
             2370      2380      2390      2400      2410      2420

     2340      2350      2360      2370      2380      2390        
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
             2430      2440      2450      2460      2470      2480

     2400      2410      2420      2430      2440      2450        
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
             2490      2500      2510      2520      2530      2540

     2460      2470      2480      2490      2500      2510        
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
             2550      2560      2570      2580      2590      2600

     2520      2530      2540      2550      2560      2570        
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
             2610      2620      2630      2640      2650      2660

     2580      2590      2600      2610      2620      2630        
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
             2670      2680      2690      2700      2710      2720

     2640      2650      2660      2670      2680      2690        
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
             2730      2740      2750      2760      2770      2780

     2700      2710      2720      2730      2740      2750        
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
             2790      2800      2810      2820      2830      2840

     2760      2770      2780      2790      2800      2810        
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
             2850      2860      2870      2880      2890      2900

     2820      2830      2840      2850      2860      2870        
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
             2910      2920      2930      2940      2950      2960

     2880      2890      2900      2910      2920      2930        
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
             2970      2980      2990      3000      3010      3020

     2940      2950      2960      2970      2980      2990        
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
             3030      3040      3050      3060      3070      3080

     3000      3010      3020      3030      3040      3050        
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
             3090      3100      3110      3120      3130      3140

     3060      3070      3080      3090      3100      3110        
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
             3150      3160      3170      3180      3190      3200

     3120      3130      3140      3150      3160      3170        
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
             3210      3220      3230      3240      3250      3260

     3180      3190      3200      3210      3220      3230        
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
             3270      3280      3290      3300      3310      3320

     3240      3250      3260      3270      3280      3290        
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
             3330      3340      3350      3360      3370      3380

     3300      3310      3320      3330      3340      3350        
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
             3390      3400      3410      3420      3430      3440

     3360      3370      3380      3390      3400      3410        
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
             3450      3460      3470      3480      3490      3500

     3420      3430      3440      3450      3460      3470        
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
             3510      3520      3530      3540      3550      3560

     3480      3490      3500      3510      3520      3530        
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
             3570      3580      3590      3600      3610      3620

     3540      3550      3560      3570      3580      3590        
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
             3630      3640      3650      3660      3670      3680

     3600      3610      3620      3630      3640      3650        
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
             3690      3700      3710      3720      3730      3740

     3660      3670      3680      3690      3700      3710        
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
             3750      3760      3770      3780      3790      3800

     3720      3730      3740      3750      3760      3770        
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
             3810      3820      3830      3840      3850      3860

     3780      3790      3800      3810      3820      3830        
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
             3870      3880      3890      3900      3910      3920

     3840      3850      3860      3870      3880      3890        
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
             3930      3940      3950      3960      3970      3980

     3900      3910      3920      3930      3940      3950        
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
             3990      4000      4010      4020      4030      4040

     3960      3970      3980      3990      4000      4010        
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
             4050      4060      4070      4080      4090      4100

     4020      4030      4040      4050      4060      4070        
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
             4110      4120      4130      4140      4150      4160

     4080      4090      4100      4110      4120      4130        
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
             4170      4180      4190      4200      4210      4220

     4140      4150      4160      4170      4180      4190        
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
             4230      4240      4250      4260      4270      4280

     4200      4210      4220      4230      4240      4250        
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
             4290      4300      4310      4320      4330      4340

     4260      4270      4280      4290      4300      4310        
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
             4350      4360      4370      4380      4390      4400

     4320      4330      4340      4350      4360      4370        
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
             4410      4420      4430      4440      4450      4460

     4380      4390      4400      4410      4420       
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
             4470      4480      4490      4500         

>--
 initn: 312 init1: 312 opt: 312  Z-score: 256.7  bits: 63.3 E(85289): 1.5e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
                                                                   
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

>>XP_011521970 (OMIM: 603333) PREDICTED: dynein heavy ch  (3973 aa)
 initn: 26259 init1: 26259 opt: 26259  Z-score: 21951.2  bits: 4077.3 E(85289):    0
Smith-Waterman score: 26259; 99.8% identity (99.9% similar) in 3972 aa overlap (456-4427:2-3973)

         430       440       450       460       470       480     
pF1KB0 EIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFELVRDV
                                     :  .::::::: ::::::::::::::::::
XP_011                              MDSCRFRAGIKDLEVMTQNLITSAFELVRDV
                                            10        20        30 

         490       500       510       520       530       540     
pF1KB0 PHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPYVAQYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPYVAQYS
              40        50        60        70        80        90 

         550       560       570       580       590       600     
pF1KB0 GKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSS
             100       110       120       130       140       150 

         610       620       630       640       650       660     
pF1KB0 LDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERA
             160       170       180       190       200       210 

         670       680       690       700       710       720     
pF1KB0 EDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF
             220       230       240       250       260       270 

         730       740       750       760       770       780     
pF1KB0 FITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHR
             280       290       300       310       320       330 

         790       800       810       820       830       840     
pF1KB0 AAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLL
             340       350       360       370       380       390 

         850       860       870       880       890       900     
pF1KB0 ELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTIS
             400       410       420       430       440       450 

         910       920       930       940       950       960     
pF1KB0 VFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREI
             460       470       480       490       500       510 

         970       980       990      1000      1010      1020     
pF1KB0 WEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLV
             520       530       540       550       560       570 

        1030      1040      1050      1060      1070      1080     
pF1KB0 QHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDL
             580       590       600       610       620       630 

        1090      1100      1110      1120      1130      1140     
pF1KB0 ANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKF
             640       650       660       670       680       690 

        1150      1160      1170      1180      1190      1200     
pF1KB0 KTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRA
             700       710       720       730       740       750 

        1210      1220      1230      1240      1250      1260     
pF1KB0 NLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAH
             760       770       780       790       800       810 

        1270      1280      1290      1300      1310      1320     
pF1KB0 GLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQR
             820       830       840       850       860       870 

        1330      1340      1350      1360      1370      1380     
pF1KB0 EFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPY
             880       890       900       910       920       930 

        1390      1400      1410      1420      1430      1440     
pF1KB0 KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILT
             940       950       960       970       980       990 

        1450      1460      1470      1480      1490      1500     
pF1KB0 VQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDT
            1000      1010      1020      1030      1040      1050 

        1510      1520      1530      1540      1550      1560     
pF1KB0 LIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDN
            1060      1070      1080      1090      1100      1110 

        1570      1580      1590      1600      1610      1620     
pF1KB0 IKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLL
            1120      1130      1140      1150      1160      1170 

        1630      1640      1650      1660      1670      1680     
pF1KB0 RNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN
            1180      1190      1200      1210      1220      1230 

        1690      1700      1710      1720      1730      1740     
pF1KB0 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF
            1240      1250      1260      1270      1280      1290 

        1750      1760      1770      1780      1790      1800     
pF1KB0 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA
            1300      1310      1320      1330      1340      1350 

        1810      1820      1830      1840      1850      1860     
pF1KB0 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL
            1360      1370      1380      1390      1400      1410 

        1870      1880      1890      1900      1910      1920     
pF1KB0 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP
            1420      1430      1440      1450      1460      1470 

        1930      1940      1950      1960      1970      1980     
pF1KB0 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR
            1480      1490      1500      1510      1520      1530 

        1990      2000      2010      2020      2030      2040     
pF1KB0 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR
            1540      1550      1560      1570      1580      1590 

        2050      2060      2070      2080      2090      2100     
pF1KB0 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC
            1600      1610      1620      1630      1640      1650 

        2110      2120      2130      2140      2150      2160     
pF1KB0 RAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWIL
            1660      1670      1680      1690      1700      1710 

        2170      2180      2190      2200      2210      2220     
pF1KB0 FDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMV
            1720      1730      1740      1750      1760      1770 

        2230      2240      2250      2260      2270      2280     
pF1KB0 YTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT
            1780      1790      1800      1810      1820      1830 

        2290      2300      2310      2320      2330      2340     
pF1KB0 SLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE
            1840      1850      1860      1870      1880      1890 

        2350      2360      2370      2380      2390      2400     
pF1KB0 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSL
            1900      1910      1920      1930      1940      1950 

        2410      2420      2430      2440      2450      2460     
pF1KB0 VANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKR
            1960      1970      1980      1990      2000      2010 

        2470      2480      2490      2500      2510      2520     
pF1KB0 TKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREM
            2020      2030      2040      2050      2060      2070 

        2530      2540      2550      2560      2570      2580     
pF1KB0 FLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIG
            2080      2090      2100      2110      2120      2130 

        2590      2600      2610      2620      2630      2640     
pF1KB0 NVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI
            2140      2150      2160      2170      2180      2190 

        2650      2660      2670      2680      2690      2700     
pF1KB0 HECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYED
            2200      2210      2220      2230      2240      2250 

        2710      2720      2730      2740      2750      2760     
pF1KB0 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG
            2260      2270      2280      2290      2300      2310 

        2770      2780      2790      2800      2810      2820     
pF1KB0 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA
            2320      2330      2340      2350      2360      2370 

        2830      2840      2850      2860      2870      2880     
pF1KB0 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN
            2380      2390      2400      2410      2420      2430 

        2890      2900      2910      2920      2930      2940     
pF1KB0 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI
            2440      2450      2460      2470      2480      2490 

        2950      2960      2970      2980      2990      3000     
pF1KB0 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN
            2500      2510      2520      2530      2540      2550 

        3010      3020      3030      3040      3050      3060     
pF1KB0 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA
            2560      2570      2580      2590      2600      2610 

        3070      3080      3090      3100      3110      3120     
pF1KB0 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI
            2620      2630      2640      2650      2660      2670 

        3130      3140      3150      3160      3170      3180     
pF1KB0 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI
            2680      2690      2700      2710      2720      2730 

        3190      3200      3210      3220      3230      3240     
pF1KB0 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA
            2740      2750      2760      2770      2780      2790 

        3250      3260      3270      3280      3290      3300     
pF1KB0 EKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLG
            2800      2810      2820      2830      2840      2850 

        3310      3320      3330      3340      3350      3360     
pF1KB0 YLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVR
            2860      2870      2880      2890      2900      2910 

        3370      3380      3390      3400      3410      3420     
pF1KB0 DWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYL
            2920      2930      2940      2950      2960      2970 

        3430      3440      3450      3460      3470      3480     
pF1KB0 RILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYI
            2980      2990      3000      3010      3020      3030 

        3490      3500      3510      3520      3530      3540     
pF1KB0 TTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGK
            3040      3050      3060      3070      3080      3090 

        3550      3560      3570      3580      3590      3600     
pF1KB0 RKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLARE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLARE
            3100      3110      3120      3130      3140      3150 

        3610      3620      3630      3640      3650      3660     
pF1KB0 AYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDY
            3160      3170      3180      3190      3200      3210 

        3670      3680      3690      3700      3710      3720     
pF1KB0 HTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNP
            3220      3230      3240      3250      3260      3270 

        3730      3740      3750      3760      3770      3780     
pF1KB0 CSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNE
            3280      3290      3300      3310      3320      3330 

        3790      3800      3810      3820      3830      3840     
pF1KB0 MQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGV
            3340      3350      3360      3370      3380      3390 

        3850      3860      3870      3880      3890      3900     
pF1KB0 DPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPN
            3400      3410      3420      3430      3440      3450 

        3910      3920      3930      3940      3950      3960     
pF1KB0 LDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMS
            3460      3470      3480      3490      3500      3510 

        3970      3980      3990      4000      4010      4020     
pF1KB0 EPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYL
            3520      3530      3540      3550      3560      3570 

        4030      4040      4050      4060      4070      4080     
pF1KB0 DEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF
            3580      3590      3600      3610      3620      3630 

        4090      4100      4110      4120      4130      4140     
pF1KB0 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA
            3640      3650      3660      3670      3680      3690 

        4150      4160      4170      4180      4190      4200     
pF1KB0 GGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILF
            3700      3710      3720      3730      3740      3750 

        4210      4220      4230      4240      4250      4260     
pF1KB0 SLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQFE
       ::::::::::::::::::::::::::.::::::::::::::::::::::.::::::::::
XP_011 SLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFE
            3760      3770      3780      3790      3800      3810 

        4270      4280      4290      4300      4310      4320     
pF1KB0 LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPP
            3820      3830      3840      3850      3860      3870 

        4330      4340      4350      4360      4370      4380     
pF1KB0 KDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYY
            3880      3890      3900      3910      3920      3930 

        4390      4400      4410      4420       
pF1KB0 YPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 YPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
            3940      3950      3960      3970   

>>XP_011521971 (OMIM: 603333) PREDICTED: dynein heavy ch  (3841 aa)
 initn: 25421 init1: 25421 opt: 25421  Z-score: 21250.8  bits: 3947.7 E(85289):    0
Smith-Waterman score: 25421; 99.9% identity (100.0% similar) in 3841 aa overlap (587-4427:1-3841)

        560       570       580       590       600       610      
pF1KB0 RIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDT
                                     ::::::::::::::::::::::::::::::
XP_011                               MVQAIDELVRKTFQEWTSSLDKDCIRRLDT
                                             10        20        30

        620       630       640       650       660       670      
pF1KB0 PLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLL
               40        50        60        70        80        90

        680       690       700       710       720       730      
pF1KB0 LVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASK
              100       110       120       130       140       150

        740       750       760       770       780       790      
pF1KB0 VQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLH
              160       170       180       190       200       210

        800       810       820       830       840       850      
pF1KB0 QDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGK
              220       230       240       250       260       270

        860       870       880       890       900       910      
pF1KB0 TSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK
              280       290       300       310       320       330

        920       930       940       950       960       970      
pF1KB0 RKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR
              340       350       360       370       380       390

        980       990      1000      1010      1020      1030      
pF1KB0 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFA
              400       410       420       430       440       450

       1040      1050      1060      1070      1080      1090      
pF1KB0 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIH
              460       470       480       490       500       510

       1100      1110      1120      1130      1140      1150      
pF1KB0 EQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDF
              520       530       540       550       560       570

       1160      1170      1180      1190      1200      1210      
pF1KB0 KKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPP
              580       590       600       610       620       630

       1220      1230      1240      1250      1260      1270      
pF1KB0 SKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAK
              640       650       660       670       680       690

       1280      1290      1300      1310      1320      1330      
pF1KB0 EYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTL
              700       710       720       730       740       750

       1340      1350      1360      1370      1380      1390      
pF1KB0 EQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGT
              760       770       780       790       800       810

       1400      1410      1420      1430      1440      1450      
pF1KB0 EEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENI
              820       830       840       850       860       870

       1460      1470      1480      1490      1500      1510      
pF1KB0 FLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDI
              880       890       900       910       920       930

       1520      1530      1540      1550      1560      1570      
pF1KB0 QKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGG
              940       950       960       970       980       990

       1580      1590      1600      1610      1620      1630      
pF1KB0 PSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFL
             1000      1010      1020      1030      1040      1050

       1640      1650      1660      1670      1680      1690      
pF1KB0 NKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA
             1060      1070      1080      1090      1100      1110

       1700      1710      1720      1730      1740      1750      
pF1KB0 IRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVI
             1120      1130      1140      1150      1160      1170

       1760      1770      1780      1790      1800      1810      
pF1KB0 RQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDL
             1180      1190      1200      1210      1220      1230

       1820      1830      1840      1850      1860      1870      
pF1KB0 GKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCIL
             1240      1250      1260      1270      1280      1290

       1880      1890      1900      1910      1920      1930      
pF1KB0 SALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLI
             1300      1310      1320      1330      1340      1350

       1940      1950      1960      1970      1980      1990      
pF1KB0 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD
             1360      1370      1380      1390      1400      1410

       2000      2010      2020      2030      2040      2050      
pF1KB0 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMG
             1420      1430      1440      1450      1460      1470

       2060      2070      2080      2090      2100      2110      
pF1KB0 LQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVR
             1480      1490      1500      1510      1520      1530

       2120      2130      2140      2150      2160      2170      
pF1KB0 EFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIE
             1540      1550      1560      1570      1580      1590

       2180      2190      2200      2210      2220      2230      
pF1KB0 NMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKP
             1600      1610      1620      1630      1640      1650

       2240      2250      2260      2270      2280      2290      
pF1KB0 YVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALAT
             1660      1670      1680      1690      1700      1710

       2300      2310      2320      2330      2340      2350      
pF1KB0 PENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEGSFPNKDTVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEGSFPNKDTVYE
             1720      1730      1740      1750      1760      1770

       2360      2370      2380      2390      2400      2410      
pF1KB0 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG
             1780      1790      1800      1810      1820      1830

       2420      2430      2440      2450      2460      2470      
pF1KB0 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK
             1840      1850      1860      1870      1880      1890

       2480      2490      2500      2510      2520      2530      
pF1KB0 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGG
             1900      1910      1920      1930      1940      1950

       2540      2550      2560      2570      2580      2590      
pF1KB0 GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMY
             1960      1970      1980      1990      2000      2010

       2600      2610      2620      2630      2640      2650      
pF1KB0 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL
             2020      2030      2040      2050      2060      2070

       2660      2670      2680      2690      2700      2710      
pF1KB0 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVM
             2080      2090      2100      2110      2120      2130

       2720      2730      2740      2750      2760      2770      
pF1KB0 ETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLAS
             2140      2150      2160      2170      2180      2190

       2780      2790      2800      2810      2820      2830      
pF1KB0 SICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNI
             2200      2210      2220      2230      2240      2250

       2840      2850      2860      2870      2880      2890      
pF1KB0 LSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMG
             2260      2270      2280      2290      2300      2310

       2900      2910      2920      2930      2940      2950      
pF1KB0 DPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTM
             2320      2330      2340      2350      2360      2370

       2960      2970      2980      2990      3000      3010      
pF1KB0 HWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDE
             2380      2390      2400      2410      2420      2430

       3020      3030      3040      3050      3060      3070      
pF1KB0 TREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK
             2440      2450      2460      2470      2480      2490

       3080      3090      3100      3110      3120      3130      
pF1KB0 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN
             2500      2510      2520      2530      2540      2550

       3140      3150      3160      3170      3180      3190      
pF1KB0 EPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSL
             2560      2570      2580      2590      2600      2610

       3200      3210      3220      3230      3240      3250      
pF1KB0 CMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYD
             2620      2630      2640      2650      2660      2670

       3260      3270      3280      3290      3300      3310      
pF1KB0 EKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAA
             2680      2690      2700      2710      2720      2730

       3320      3330      3340      3350      3360      3370      
pF1KB0 FLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDA
             2740      2750      2760      2770      2780      2790

       3380      3390      3400      3410      3420      3430      
pF1KB0 FSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGY
             2800      2810      2820      2830      2840      2850

       3440      3450      3460      3470      3480      3490      
pF1KB0 PVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSP
             2860      2870      2880      2890      2900      2910

       3500      3510      3520      3530      3540      3550      
pF1KB0 ETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEIL
             2920      2930      2940      2950      2960      2970

       3560      3570      3580      3590      3600      3610      
pF1KB0 RLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASI
             2980      2990      3000      3010      3020      3030

       3620      3630      3640      3650      3660      3670      
pF1KB0 LFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCR
             3040      3050      3060      3070      3080      3090

       3680      3690      3700      3710      3720      3730      
pF1KB0 TLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWD
             3100      3110      3120      3130      3140      3150

       3740      3750      3760      3770      3780      3790      
pF1KB0 NITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLR
             3160      3170      3180      3190      3200      3210

       3800      3810      3820      3830      3840      3850      
pF1KB0 QDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAE
             3220      3230      3240      3250      3260      3270

       3860      3870      3880      3890      3900      3910      
pF1KB0 HMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVE
             3280      3290      3300      3310      3320      3330

       3920      3930      3940      3950      3960      3970      
pF1KB0 DPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPA
             3340      3350      3360      3370      3380      3390

       3980      3990      4000      4010      4020      4030      
pF1KB0 KYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDAL
             3400      3410      3420      3430      3440      3450

       4040      4050      4060      4070      4080      4090      
pF1KB0 KYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYK
             3460      3470      3480      3490      3500      3510

       4100      4110      4120      4130      4140      4150      
pF1KB0 EYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLE
             3520      3530      3540      3550      3560      3570

       4160      4170      4180      4190      4200      4210      
pF1KB0 LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQG
             3580      3590      3600      3610      3620      3630

       4220      4230      4240      4250      4260      4270      
pF1KB0 LIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQFELWASRARPPVI
       :::::::::::::::.::::::::::::::::::::::.:::::::::::::::::::::
XP_011 LIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVI
             3640      3650      3660      3670      3680      3690

       4280      4290      4300      4310      4320      4330      
pF1KB0 FWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYL
             3700      3710      3720      3730      3740      3750

       4340      4350      4360      4370      4380      4390      
pF1KB0 EGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRA
             3760      3770      3780      3790      3800      3810

       4400      4410      4420       
pF1KB0 SFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::
XP_011 SFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
             3820      3830      3840 

>>XP_016879707 (OMIM: 603333) PREDICTED: dynein heavy ch  (3844 aa)
 initn: 25102 init1: 25102 opt: 25102  Z-score: 20984.1  bits: 3898.3 E(85289):    0
Smith-Waterman score: 25102; 99.9% identity (100.0% similar) in 3793 aa overlap (635-4427:52-3844)

          610       620       630       640       650       660    
pF1KB0 SLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAER
                                     .:::::::::::::::::::::::::::::
XP_016 FFAGACPLQLNFKAKRQLPFIITLEPHLPWRSLLILFAEIDYWERLLFETPHYVVNVAER
              30        40        50        60        70        80 

          670       680       690       700       710       720    
pF1KB0 AEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASA
              90       100       110       120       130       140 

          730       740       750       760       770       780    
pF1KB0 FFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREH
             150       160       170       180       190       200 

          790       800       810       820       830       840    
pF1KB0 RAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSL
             210       220       230       240       250       260 

          850       860       870       880       890       900    
pF1KB0 LELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI
             270       280       290       300       310       320 

          910       920       930       940       950       960    
pF1KB0 SVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYRE
             330       340       350       360       370       380 

          970       980       990      1000      1010      1020    
pF1KB0 IWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSL
             390       400       410       420       430       440 

         1030      1040      1050      1060      1070      1080    
pF1KB0 VQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHD
             450       460       470       480       490       500 

         1090      1100      1110      1120      1130      1140    
pF1KB0 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK
             510       520       530       540       550       560 

         1150      1160      1170      1180      1190      1200    
pF1KB0 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR
             570       580       590       600       610       620 

         1210      1220      1230      1240      1250      1260    
pF1KB0 ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTA
             630       640       650       660       670       680 

         1270      1280      1290      1300      1310      1320    
pF1KB0 HGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQ
             690       700       710       720       730       740 

         1330      1340      1350      1360      1370      1380    
pF1KB0 REFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVP
             750       760       770       780       790       800 

         1390      1400      1410      1420      1430      1440    
pF1KB0 YKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMIL
             810       820       830       840       850       860 

         1450      1460      1470      1480      1490      1500    
pF1KB0 TVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLD
             870       880       890       900       910       920 

         1510      1520      1530      1540      1550      1560    
pF1KB0 TLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFD
             930       940       950       960       970       980 

         1570      1580      1590      1600      1610      1620    
pF1KB0 NIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDL
             990      1000      1010      1020      1030      1040 

         1630      1640      1650      1660      1670      1680    
pF1KB0 LRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKK
            1050      1060      1070      1080      1090      1100 

         1690      1700      1710      1720      1730      1740    
pF1KB0 NQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLR
            1110      1120      1130      1140      1150      1160 

         1750      1760      1770      1780      1790      1800    
pF1KB0 FYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGP
            1170      1180      1190      1200      1210      1220 

         1810      1820      1830      1840      1850      1860    
pF1KB0 AGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEV
            1230      1240      1250      1260      1270      1280 

         1870      1880      1890      1900      1910      1920    
pF1KB0 LSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFR
            1290      1300      1310      1320      1330      1340 

         1930      1940      1950      1960      1970      1980    
pF1KB0 PIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLL
            1350      1360      1370      1380      1390      1400 

         1990      2000      2010      2020      2030      2040    
pF1KB0 RYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKL
            1410      1420      1430      1440      1450      1460 

         2050      2060      2070      2080      2090      2100    
pF1KB0 RETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSL
            1470      1480      1490      1500      1510      1520 

         2110      2120      2130      2140      2150      2160    
pF1KB0 CRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWI
            1530      1540      1550      1560      1570      1580 

         2170      2180      2190      2200      2210      2220    
pF1KB0 LFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGM
            1590      1600      1610      1620      1630      1640 

         2230      2240      2250      2260      2270      2280    
pF1KB0 VYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGI
            1650      1660      1670      1680      1690      1700 

         2290      2300      2310      2320      2330      2340    
pF1KB0 TSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI
            1710      1720      1730      1740      1750      1760 

         2350      2360      2370      2380      2390      2400    
pF1KB0 EGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSS
            1770      1780      1790      1800      1810      1820 

         2410      2420      2430      2440      2450      2460    
pF1KB0 LVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEK
            1830      1840      1850      1860      1870      1880 

         2470      2480      2490      2500      2510      2520    
pF1KB0 RTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIRE
            1890      1900      1910      1920      1930      1940 

         2530      2540      2550      2560      2570      2580    
pF1KB0 MFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPI
            1950      1960      1970      1980      1990      2000 

         2590      2600      2610      2620      2630      2640    
pF1KB0 GNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLW
            2010      2020      2030      2040      2050      2060 

         2650      2660      2670      2680      2690      2700    
pF1KB0 IHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYE
            2070      2080      2090      2100      2110      2120 

         2710      2720      2730      2740      2750      2760    
pF1KB0 DLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIG
            2130      2140      2150      2160      2170      2180 

         2770      2780      2790      2800      2810      2820    
pF1KB0 GSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQI
            2190      2200      2210      2220      2230      2240 

         2830      2840      2850      2860      2870      2880    
pF1KB0 ADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQN
            2250      2260      2270      2280      2290      2300 

         2890      2900      2910      2920      2930      2940    
pF1KB0 NLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQEN
            2310      2320      2330      2340      2350      2360 

         2950      2960      2970      2980      2990      3000    
pF1KB0 IHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQA
            2370      2380      2390      2400      2410      2420 

         3010      3020      3030      3040      3050      3060    
pF1KB0 NKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT
            2430      2440      2450      2460      2470      2480 

         3070      3080      3090      3100      3110      3120    
pF1KB0 ANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVE
            2490      2500      2510      2520      2530      2540 

         3130      3140      3150      3160      3170      3180    
pF1KB0 IVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD
            2550      2560      2570      2580      2590      2600 

         3190      3200      3210      3220      3230      3240    
pF1KB0 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV
            2610      2620      2630      2640      2650      2660 

         3250      3260      3270      3280      3290      3300    
pF1KB0 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL
            2670      2680      2690      2700      2710      2720 

         3310      3320      3330      3340      3350      3360    
pF1KB0 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV
            2730      2740      2750      2760      2770      2780 

         3370      3380      3390      3400      3410      3420    
pF1KB0 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY
            2790      2800      2810      2820      2830      2840 

         3430      3440      3450      3460      3470      3480    
pF1KB0 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY
            2850      2860      2870      2880      2890      2900 

         3490      3500      3510      3520      3530      3540    
pF1KB0 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG
            2910      2920      2930      2940      2950      2960 

         3550      3560      3570      3580      3590      3600    
pF1KB0 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR
            2970      2980      2990      3000      3010      3020 

         3610      3620      3630      3640      3650      3660    
pF1KB0 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND
            3030      3040      3050      3060      3070      3080 

         3670      3680      3690      3700      3710      3720    
pF1KB0 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN
            3090      3100      3110      3120      3130      3140 

         3730      3740      3750      3760      3770      3780    
pF1KB0 PCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACN
            3150      3160      3170      3180      3190      3200 

         3790      3800      3810      3820      3830      3840    
pF1KB0 EMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPG
            3210      3220      3230      3240      3250      3260 

         3850      3860      3870      3880      3890      3900    
pF1KB0 VDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP
            3270      3280      3290      3300      3310      3320 

         3910      3920      3930      3940      3950      3960    
pF1KB0 NLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLM
            3330      3340      3350      3360      3370      3380 

         3970      3980      3990      4000      4010      4020    
pF1KB0 SEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLY
            3390      3400      3410      3420      3430      3440 

         4030      4040      4050      4060      4070      4080    
pF1KB0 LDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY
            3450      3460      3470      3480      3490      3500 

         4090      4100      4110      4120      4130      4140    
pF1KB0 FIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTR
            3510      3520      3530      3540      3550      3560 

         4150      4160      4170      4180      4190      4200    
pF1KB0 AGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTIL
            3570      3580      3590      3600      3610      3620 

         4210      4220      4230      4240      4250      4260    
pF1KB0 FSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQF
       :::::::::::::::::::::::::::.::::::::::::::::::::::.:::::::::
XP_016 FSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQF
            3630      3640      3650      3660      3670      3680 

         4270      4280      4290      4300      4310      4320    
pF1KB0 ELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYP
            3690      3700      3710      3720      3730      3740 

         4330      4340      4350      4360      4370      4380    
pF1KB0 PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY
            3750      3760      3770      3780      3790      3800 

         4390      4400      4410      4420       
pF1KB0 YYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 YYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
            3810      3820      3830      3840    

>>XP_016879708 (OMIM: 603333) PREDICTED: dynein heavy ch  (3799 aa)
 initn: 21620 init1: 21620 opt: 21620  Z-score: 18072.9  bits: 3359.7 E(85289):    0
Smith-Waterman score: 23700; 97.8% identity (97.8% similar) in 3703 aa overlap (51-3671:51-3753)

               30        40        50        60        70        80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
                                     ::::::::::::::::::::::::::::::
XP_016 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
               30        40        50        60        70        80

               90       100       110       120       130       140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
               90       100       110       120       130       140

              150       160       170       180       190       200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
              150       160       170       180       190       200

              210       220       230       240       250       260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
              210       220       230       240       250       260

              270       280       290       300       310       320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
              270       280       290       300       310       320

              330       340       350       360       370       380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
              330       340       350       360       370       380

              390                                                  
pF1KB0 RERLTSLFRK--------------------------------------------------
       ::::::::::                                                  
XP_016 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
              390       400       410       420       430       440

                                              400       410        
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
                                       ::::::::::::::::::::::::::::
XP_016 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
              450       460       470       480       490       500

      420       430       440       450       460       470        
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
              510       520       530       540       550       560

      480       490       500       510       520       530        
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
              570       580       590       600       610       620

      540       550       560       570       580       590        
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
              630       640       650       660       670       680

      600       610       620       630       640       650        
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
              690       700       710       720       730       740

      660       670       680       690       700       710        
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
              750       760       770       780       790       800

      720       730       740       750       760       770        
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
              810       820       830       840       850       860

      780       790       800       810       820       830        
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
              870       880       890       900       910       920

      840       850       860       870       880       890        
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
              930       940       950       960       970       980

      900       910       920       930       940       950        
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
              990      1000      1010      1020      1030      1040

      960       970       980       990      1000      1010        
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
             1050      1060      1070      1080      1090      1100

     1020      1030      1040      1050      1060      1070        
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
             1110      1120      1130      1140      1150      1160

     1080      1090      1100      1110      1120      1130        
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
             1170      1180      1190      1200      1210      1220

     1140      1150      1160      1170      1180      1190        
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
             1230      1240      1250      1260      1270      1280

     1200      1210      1220      1230      1240      1250        
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
             1290      1300      1310      1320      1330      1340

     1260      1270      1280      1290      1300      1310        
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
             1350      1360      1370      1380      1390      1400

     1320      1330      1340      1350      1360      1370        
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
             1410      1420      1430      1440      1450      1460

     1380      1390      1400      1410      1420      1430        
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
             1470      1480      1490      1500      1510      1520

     1440      1450      1460      1470      1480      1490        
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
             1530      1540      1550      1560      1570      1580

     1500      1510      1520      1530      1540      1550        
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
             1590      1600      1610      1620      1630      1640

     1560      1570      1580      1590      1600      1610        
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
             1650      1660      1670      1680      1690      1700

     1620      1630      1640      1650      1660      1670        
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
             1710      1720      1730      1740      1750      1760

     1680      1690      1700      1710      1720      1730        
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
             1770      1780      1790      1800      1810      1820

     1740      1750      1760      1770      1780      1790        
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
             1830      1840      1850      1860      1870      1880

     1800      1810      1820      1830      1840      1850        
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
             1890      1900      1910      1920      1930      1940

     1860      1870      1880      1890      1900      1910        
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
             1950      1960      1970      1980      1990      2000

     1920      1930      1940      1950      1960      1970        
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
             2010      2020      2030      2040      2050      2060

     1980      1990      2000      2010      2020      2030        
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
             2070      2080      2090      2100      2110      2120

     2040      2050      2060      2070      2080      2090        
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
             2130      2140      2150      2160      2170      2180

     2100      2110      2120      2130      2140      2150        
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
             2190      2200      2210      2220      2230      2240

     2160      2170      2180      2190      2200      2210        
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
             2250      2260      2270      2280      2290      2300

     2220      2230      2240      2250      2260      2270        
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
             2310      2320      2330      2340      2350      2360

     2280      2290      2300      2310      2320      2330        
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
             2370      2380      2390      2400      2410      2420

     2340      2350      2360      2370      2380      2390        
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
             2430      2440      2450      2460      2470      2480

     2400      2410      2420      2430      2440      2450        
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
             2490      2500      2510      2520      2530      2540

     2460      2470      2480      2490      2500      2510        
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
             2550      2560      2570      2580      2590      2600

     2520      2530      2540      2550      2560      2570        
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
             2610      2620      2630      2640      2650      2660

     2580      2590      2600      2610      2620      2630        
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
             2670      2680      2690      2700      2710      2720

     2640      2650      2660      2670      2680      2690        
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
             2730      2740      2750      2760      2770      2780

     2700      2710      2720      2730      2740      2750        
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
             2790      2800      2810      2820      2830      2840

     2760      2770      2780      2790      2800      2810        
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
             2850      2860      2870      2880      2890      2900

     2820      2830      2840      2850      2860      2870        
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
             2910      2920      2930      2940      2950      2960

     2880      2890      2900      2910      2920      2930        
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
             2970      2980      2990      3000      3010      3020

     2940      2950      2960      2970      2980      2990        
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
             3030      3040      3050      3060      3070      3080

     3000      3010      3020      3030      3040      3050        
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
             3090      3100      3110      3120      3130      3140

     3060      3070      3080      3090      3100      3110        
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
             3150      3160      3170      3180      3190      3200

     3120      3130      3140      3150      3160      3170        
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
             3210      3220      3230      3240      3250      3260

     3180      3190      3200      3210      3220      3230        
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
             3270      3280      3290      3300      3310      3320

     3240      3250      3260      3270      3280      3290        
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
             3330      3340      3350      3360      3370      3380

     3300      3310      3320      3330      3340      3350        
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
             3390      3400      3410      3420      3430      3440

     3360      3370      3380      3390      3400      3410        
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
             3450      3460      3470      3480      3490      3500

     3420      3430      3440      3450      3460      3470        
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
             3510      3520      3530      3540      3550      3560

     3480      3490      3500      3510      3520      3530        
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
             3570      3580      3590      3600      3610      3620

     3540      3550      3560      3570      3580      3590        
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
             3630      3640      3650      3660      3670      3680

     3600      3610      3620      3630      3640      3650        
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
             3690      3700      3710      3720      3730      3740

     3660      3670      3680      3690      3700      3710        
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
       :::::::::::::                                               
XP_016 IDYLNDYHTYAVYSLGQLLGNFPSPAGRDIITDGLSVLSETVAYSSLCLQDLAECLARQ 
             3750      3760      3770      3780      3790          

>--
 initn: 312 init1: 312 opt: 312  Z-score: 257.8  bits: 63.3 E(85289): 1.3e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_016 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
                                                                   
XP_016 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

>>XP_011521972 (OMIM: 603333) PREDICTED: dynein heavy ch  (3551 aa)
 initn: 20302 init1: 20302 opt: 20302  Z-score: 16971.4  bits: 3155.8 E(85289):    0
Smith-Waterman score: 22382; 97.6% identity (97.6% similar) in 3494 aa overlap (51-3462:51-3544)

               30        40        50        60        70        80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
                                     ::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
               30        40        50        60        70        80

               90       100       110       120       130       140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
               90       100       110       120       130       140

              150       160       170       180       190       200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
              150       160       170       180       190       200

              210       220       230       240       250       260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
              210       220       230       240       250       260

              270       280       290       300       310       320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
              270       280       290       300       310       320

              330       340       350       360       370       380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
              330       340       350       360       370       380

              390                                                  
pF1KB0 RERLTSLFRK--------------------------------------------------
       ::::::::::                                                  
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
              390       400       410       420       430       440

                                              400       410        
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
                                       ::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
              450       460       470       480       490       500

      420       430       440       450       460       470        
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
              510       520       530       540       550       560

      480       490       500       510       520       530        
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
              570       580       590       600       610       620

      540       550       560       570       580       590        
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
              630       640       650       660       670       680

      600       610       620       630       640       650        
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
              690       700       710       720       730       740

      660       670       680       690       700       710        
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
              750       760       770       780       790       800

      720       730       740       750       760       770        
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
              810       820       830       840       850       860

      780       790       800       810       820       830        
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
              870       880       890       900       910       920

      840       850       860       870       880       890        
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
              930       940       950       960       970       980

      900       910       920       930       940       950        
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
              990      1000      1010      1020      1030      1040

      960       970       980       990      1000      1010        
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
             1050      1060      1070      1080      1090      1100

     1020      1030      1040      1050      1060      1070        
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
             1110      1120      1130      1140      1150      1160

     1080      1090      1100      1110      1120      1130        
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
             1170      1180      1190      1200      1210      1220

     1140      1150      1160      1170      1180      1190        
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
             1230      1240      1250      1260      1270      1280

     1200      1210      1220      1230      1240      1250        
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
             1290      1300      1310      1320      1330      1340

     1260      1270      1280      1290      1300      1310        
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
             1350      1360      1370      1380      1390      1400

     1320      1330      1340      1350      1360      1370        
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
             1410      1420      1430      1440      1450      1460

     1380      1390      1400      1410      1420      1430        
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
             1470      1480      1490      1500      1510      1520

     1440      1450      1460      1470      1480      1490        
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
             1530      1540      1550      1560      1570      1580

     1500      1510      1520      1530      1540      1550        
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
             1590      1600      1610      1620      1630      1640

     1560      1570      1580      1590      1600      1610        
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
             1650      1660      1670      1680      1690      1700

     1620      1630      1640      1650      1660      1670        
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
             1710      1720      1730      1740      1750      1760

     1680      1690      1700      1710      1720      1730        
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
             1770      1780      1790      1800      1810      1820

     1740      1750      1760      1770      1780      1790        
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
             1830      1840      1850      1860      1870      1880

     1800      1810      1820      1830      1840      1850        
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
             1890      1900      1910      1920      1930      1940

     1860      1870      1880      1890      1900      1910        
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
             1950      1960      1970      1980      1990      2000

     1920      1930      1940      1950      1960      1970        
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
             2010      2020      2030      2040      2050      2060

     1980      1990      2000      2010      2020      2030        
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
             2070      2080      2090      2100      2110      2120

     2040      2050      2060      2070      2080      2090        
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
             2130      2140      2150      2160      2170      2180

     2100      2110      2120      2130      2140      2150        
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
             2190      2200      2210      2220      2230      2240

     2160      2170      2180      2190      2200      2210        
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
             2250      2260      2270      2280      2290      2300

     2220      2230      2240      2250      2260      2270        
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
             2310      2320      2330      2340      2350      2360

     2280      2290      2300      2310      2320      2330        
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
             2370      2380      2390      2400      2410      2420

     2340      2350      2360      2370      2380      2390        
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
             2430      2440      2450      2460      2470      2480

     2400      2410      2420      2430      2440      2450        
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
             2490      2500      2510      2520      2530      2540

     2460      2470      2480      2490      2500      2510        
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
             2550      2560      2570      2580      2590      2600

     2520      2530      2540      2550      2560      2570        
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
             2610      2620      2630      2640      2650      2660

     2580      2590      2600      2610      2620      2630        
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
             2670      2680      2690      2700      2710      2720

     2640      2650      2660      2670      2680      2690        
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
             2730      2740      2750      2760      2770      2780

     2700      2710      2720      2730      2740      2750        
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
             2790      2800      2810      2820      2830      2840

     2760      2770      2780      2790      2800      2810        
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
             2850      2860      2870      2880      2890      2900

     2820      2830      2840      2850      2860      2870        
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
             2910      2920      2930      2940      2950      2960

     2880      2890      2900      2910      2920      2930        
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
             2970      2980      2990      3000      3010      3020

     2940      2950      2960      2970      2980      2990        
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
             3030      3040      3050      3060      3070      3080

     3000      3010      3020      3030      3040      3050        
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
             3090      3100      3110      3120      3130      3140

     3060      3070      3080      3090      3100      3110        
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
             3150      3160      3170      3180      3190      3200

     3120      3130      3140      3150      3160      3170        
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
             3210      3220      3230      3240      3250      3260

     3180      3190      3200      3210      3220      3230        
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
             3270      3280      3290      3300      3310      3320

     3240      3250      3260      3270      3280      3290        
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
             3330      3340      3350      3360      3370      3380

     3300      3310      3320      3330      3340      3350        
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
             3390      3400      3410      3420      3430      3440

     3360      3370      3380      3390      3400      3410        
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
             3450      3460      3470      3480      3490      3500

     3420      3430      3440      3450      3460      3470        
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIDSPGLGP         
             3510      3520      3530      3540      3550          

     3480      3490      3500      3510      3520      3530        
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV

>--
 initn: 312 init1: 312 opt: 312  Z-score: 258.2  bits: 63.3 E(85289): 1.2e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
                                                                   
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120

>>XP_011521968 (OMIM: 603333) PREDICTED: dynein heavy ch  (4446 aa)
 initn: 14541 init1: 14378 opt: 14378  Z-score: 12017.1  bits: 2239.4 E(85289):    0
Smith-Waterman score: 28307; 96.7% identity (96.7% similar) in 4459 aa overlap (51-4427:51-4446)

               30        40        50        60        70        80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
                                     ::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
               30        40        50        60        70        80

               90       100       110       120       130       140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
               90       100       110       120       130       140

              150       160       170       180       190       200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
              150       160       170       180       190       200

              210       220       230       240       250       260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
              210       220       230       240       250       260

              270       280       290       300       310       320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
              270       280       290       300       310       320

              330       340       350       360       370       380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
              330       340       350       360       370       380

              390                                                  
pF1KB0 RERLTSLFRK--------------------------------------------------
       ::::::::::                                                  
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
              390       400       410       420       430       440

                                              400       410        
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
                                       ::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
              450       460       470       480       490       500

      420       430       440       450       460       470        
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
              510       520       530       540       550       560

      480       490       500       510       520       530        
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
              570       580       590       600       610       620

      540       550       560       570       580       590        
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
              630       640       650       660       670       680

      600       610       620       630       640       650        
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
              690       700       710       720       730       740

      660       670       680       690       700       710        
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
              750       760       770       780       790       800

      720       730       740       750       760       770        
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
              810       820       830       840       850       860

      780       790       800       810       820       830        
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
              870       880       890       900       910       920

      840       850       860       870       880       890        
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
              930       940       950       960       970       980

      900       910       920       930       940       950        
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
              990      1000      1010      1020      1030      1040

      960       970       980       990      1000      1010        
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
             1050      1060      1070      1080      1090      1100

     1020      1030      1040      1050      1060      1070        
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
             1110      1120      1130      1140      1150      1160

     1080      1090      1100      1110      1120      1130        
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
             1170      1180      1190      1200      1210      1220

     1140      1150      1160      1170      1180      1190        
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
             1230      1240      1250      1260      1270      1280

     1200      1210      1220      1230      1240      1250        
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
             1290      1300      1310      1320      1330      1340

     1260      1270      1280      1290      1300      1310        
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
             1350      1360      1370      1380      1390      1400

     1320      1330      1340      1350      1360      1370        
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
             1410      1420      1430      1440      1450      1460

     1380      1390      1400      1410      1420      1430        
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
             1470      1480      1490      1500      1510      1520

     1440      1450      1460      1470      1480      1490        
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
             1530      1540      1550      1560      1570      1580

     1500      1510      1520      1530      1540      1550        
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
             1590      1600      1610      1620      1630      1640

     1560      1570      1580      1590      1600      1610        
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
             1650      1660      1670      1680      1690      1700

     1620      1630      1640      1650      1660      1670        
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
             1710      1720      1730      1740      1750      1760

     1680      1690      1700      1710      1720      1730        
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
             1770      1780      1790      1800      1810      1820

     1740      1750      1760      1770      1780      1790        
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
             1830      1840      1850      1860      1870      1880

     1800      1810      1820      1830      1840      1850        
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
             1890      1900      1910      1920      1930      1940

     1860      1870      1880      1890      1900      1910        
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
             1950      1960      1970      1980      1990      2000

     1920      1930      1940      1950      1960      1970        
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
             2010      2020      2030      2040      2050      2060

     1980      1990      2000      2010      2020      2030        
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
             2070      2080      2090      2100      2110      2120

     2040      2050      2060      2070      2080      2090        
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
             2130      2140      2150      2160      2170      2180

     2100      2110      2120      2130      2140      2150        
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
             2190      2200      2210      2220      2230      2240

     2160      2170      2180      2190      2200      2210        
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
             2250      2260      2270      2280      2290      2300

     2220      2230      2240      2250      2260      2270        
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
             2310      2320      2330      2340      2350      2360

     2280      2290      2300      2310      2320      2330        
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
             2370      2380      2390      2400      2410      2420

     2340      2350      2360      2370      2380      2390        
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
             2430      2440      2450      2460      2470      2480

     2400      2410      2420      2430      2440      2450        
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
             2490      2500      2510      2520      2530      2540

     2460      2470      2480      2490      2500      2510        
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
             2550      2560      2570      2580      2590      2600

     2520      2530      2540      2550      2560      2570        
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
       ::::::::::::::::::::::::::::::::::::::::                    
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPT--------------------
             2610      2620      2630      2640                    

     2580      2590      2600      2610      2620      2630        
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
                                                  :::::::::::::::::
XP_011 -------------------------------------------VFQGMLRANKDFHDTKS
                                                        2650       

     2640      2650      2660      2670      2680      2690        
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
      2660      2670      2680      2690      2700      2710       

     2700      2710      2720      2730      2740      2750        
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
      2720      2730      2740      2750      2760      2770       

     2760      2770      2780      2790      2800      2810        
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
      2780      2790      2800      2810      2820      2830       

     2820      2830      2840      2850      2860      2870        
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
      2840      2850      2860      2870      2880      2890       

     2880      2890      2900      2910      2920      2930        
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
      2900      2910      2920      2930      2940      2950       

     2940      2950      2960      2970      2980      2990        
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
      2960      2970      2980      2990      3000      3010       

     3000      3010      3020      3030      3040      3050        
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
      3020      3030      3040      3050      3060      3070       

     3060      3070      3080      3090      3100      3110        
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
      3080      3090      3100      3110      3120      3130       

     3120      3130      3140      3150      3160      3170        
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
      3140      3150      3160      3170      3180      3190       

     3180      3190      3200      3210      3220      3230        
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
      3200      3210      3220      3230      3240      3250       

     3240      3250      3260      3270      3280      3290        
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
      3260      3270      3280      3290      3300      3310       

     3300      3310      3320      3330      3340      3350        
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
      3320      3330      3340      3350      3360      3370       

     3360      3370      3380      3390      3400      3410        
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
      3380      3390      3400      3410      3420      3430       

     3420      3430      3440      3450      3460      3470        
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
      3440      3450      3460      3470      3480      3490       

     3480      3490      3500      3510      3520      3530        
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
      3500      3510      3520      3530      3540      3550       

     3540      3550      3560      3570      3580      3590        
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
      3560      3570      3580      3590      3600      3610       

     3600      3610      3620      3630      3640      3650        
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
      3620      3630      3640      3650      3660      3670       

     3660      3670      3680      3690      3700      3710        
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
      3680      3690      3700      3710      3720      3730       

     3720      3730      3740      3750      3760      3770        
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
      3740      3750      3760      3770      3780      3790       

     3780      3790      3800      3810      3820      3830        
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
      3800      3810      3820      3830      3840      3850       

     3840      3850      3860      3870      3880      3890        
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
      3860      3870      3880      3890      3900      3910       

     3900      3910      3920      3930      3940      3950        
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
      3920      3930      3940      3950      3960      3970       

     3960      3970      3980      3990      4000      4010        
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
      3980      3990      4000      4010      4020      4030       

     4020      4030      4040      4050      4060      4070        
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
      4040      4050      4060      4070      4080      4090       

     4080      4090      4100      4110      4120      4130        
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
      4100      4110      4120      4130      4140      4150       

     4140      4150      4160      4170      4180      4190        
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
      4160      4170      4180      4190      4200      4210       

     4200      4210      4220      4230      4240      4250        
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
      4220      4230      4240      4250      4260      4270       

     4260      4270      4280      4290      4300      4310        
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
      4280      4290      4300      4310      4320      4330       

     4320      4330      4340      4350      4360      4370        
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
      4340      4350      4360      4370      4380      4390       

     4380      4390      4400      4410      4420       
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
      4400      4410      4420      4430      4440      

>--
 initn: 312 init1: 312 opt: 312  Z-score: 256.8  bits: 63.3 E(85289): 1.4e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
                                                                   
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
               70        80        90       100       110       120




4427 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:03:05 2016 done: Fri Nov  4 02:03:10 2016
 Total Scan time: 28.400 Total Display time:  6.010

Function used was FASTA [36.3.4 Apr, 2011]
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