Result of FASTA (omim) for
pF1KA0772
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0772, 468 aa
1>>>pF1KA0772 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6382+/-0.000357; mu= 17.1089+/- 0.022
mean_var=86.4511+/-16.970, 0's: 0 Z-trim(115.2): 138 B-trim: 162 in 1/53
Lambda= 0.137940
statistics sampled from 25319 (25457) to 25319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.298), width: 16
Scan time: 8.920
The best scores are: opt bits E(85289)
NP_055650 (OMIM: 606731,616340) oxysterol-binding ( 468) 3236 654.0 2.5e-187
XP_016883654 (OMIM: 606731,616340) PREDICTED: oxys ( 480) 3159 638.7 1e-182
NP_653081 (OMIM: 606731,616340) oxysterol-binding ( 480) 3159 638.7 1e-182
XP_016883656 (OMIM: 606731,616340) PREDICTED: oxys ( 388) 2712 549.7 5.3e-156
XP_016883653 (OMIM: 606731,616340) PREDICTED: oxys ( 516) 2416 490.8 3.6e-138
XP_016883652 (OMIM: 606731,616340) PREDICTED: oxys ( 516) 2416 490.8 3.6e-138
XP_016881022 (OMIM: 606730) PREDICTED: oxysterol-b ( 437) 2226 453.0 7.6e-127
NP_060500 (OMIM: 606730) oxysterol-binding protein ( 437) 2226 453.0 7.6e-127
XP_016881023 (OMIM: 606730) PREDICTED: oxysterol-b ( 437) 2226 453.0 7.6e-127
NP_001229437 (OMIM: 606730) oxysterol-binding prot ( 568) 2227 453.3 8.1e-127
XP_006722443 (OMIM: 606730) PREDICTED: oxysterol-b ( 925) 2227 453.4 1.2e-126
NP_542164 (OMIM: 606730) oxysterol-binding protein ( 950) 2227 453.4 1.2e-126
XP_016881019 (OMIM: 606730) PREDICTED: oxysterol-b ( 968) 2227 453.4 1.2e-126
XP_016883657 (OMIM: 606731,616340) PREDICTED: oxys ( 370) 2133 434.4 2.5e-121
NP_001265578 (OMIM: 606731,616340) oxysterol-bindi ( 370) 1972 402.4 1.1e-111
XP_016883655 (OMIM: 606731,616340) PREDICTED: oxys ( 424) 1969 401.8 1.9e-111
XP_016883659 (OMIM: 606731,616340) PREDICTED: oxys ( 292) 1826 373.2 5.1e-103
XP_006722445 (OMIM: 606730) PREDICTED: oxysterol-b ( 905) 1790 366.4 1.8e-100
XP_016883658 (OMIM: 606731,616340) PREDICTED: oxys ( 328) 1083 225.4 1.8e-58
XP_006715747 (OMIM: 606732) PREDICTED: oxysterol-b ( 534) 786 166.5 1.6e-40
XP_016867438 (OMIM: 606732) PREDICTED: oxysterol-b ( 807) 786 166.6 2.3e-40
XP_006715746 (OMIM: 606732) PREDICTED: oxysterol-b ( 820) 786 166.6 2.3e-40
NP_663162 (OMIM: 606732) oxysterol-binding protein ( 820) 786 166.6 2.3e-40
XP_011513561 (OMIM: 606732) PREDICTED: oxysterol-b ( 843) 786 166.6 2.3e-40
XP_016867437 (OMIM: 606732) PREDICTED: oxysterol-b ( 843) 786 166.6 2.3e-40
NP_663161 (OMIM: 606732) oxysterol-binding protein ( 851) 786 166.6 2.4e-40
XP_006715745 (OMIM: 606732) PREDICTED: oxysterol-b ( 851) 786 166.6 2.4e-40
XP_006715744 (OMIM: 606732) PREDICTED: oxysterol-b ( 856) 786 166.6 2.4e-40
NP_663160 (OMIM: 606732) oxysterol-binding protein ( 856) 786 166.6 2.4e-40
XP_011513560 (OMIM: 606732) PREDICTED: oxysterol-b ( 887) 786 166.6 2.4e-40
NP_056365 (OMIM: 606732) oxysterol-binding protein ( 887) 786 166.6 2.4e-40
XP_005249755 (OMIM: 606732) PREDICTED: oxysterol-b ( 887) 786 166.6 2.4e-40
XP_016858766 (OMIM: 606734) PREDICTED: oxysterol-b ( 836) 775 164.4 1.1e-39
XP_016858764 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 775 164.4 1.1e-39
XP_016858763 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 775 164.4 1.1e-39
XP_016858765 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 775 164.4 1.1e-39
XP_016858762 (OMIM: 606734) PREDICTED: oxysterol-b ( 872) 775 164.4 1.1e-39
XP_016858761 (OMIM: 606734) PREDICTED: oxysterol-b ( 892) 775 164.4 1.1e-39
XP_016858760 (OMIM: 606734) PREDICTED: oxysterol-b ( 898) 775 164.5 1.1e-39
NP_001188411 (OMIM: 606734) oxysterol-binding prot ( 898) 775 164.5 1.1e-39
XP_016858759 (OMIM: 606734) PREDICTED: oxysterol-b ( 903) 775 164.5 1.1e-39
NP_001188410 (OMIM: 606734) oxysterol-binding prot ( 903) 775 164.5 1.1e-39
XP_016858757 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 775 164.5 1.1e-39
XP_016858758 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 775 164.5 1.1e-39
XP_011508841 (OMIM: 606734) PREDICTED: oxysterol-b ( 928) 775 164.5 1.1e-39
NP_115912 (OMIM: 606734) oxysterol-binding protein ( 934) 775 164.5 1.2e-39
NP_665682 (OMIM: 606734) oxysterol-binding protein ( 938) 775 164.5 1.2e-39
XP_016858756 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 775 164.5 1.2e-39
XP_016858755 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 775 164.5 1.2e-39
NP_001188409 (OMIM: 606734) oxysterol-binding prot ( 959) 775 164.5 1.2e-39
>>NP_055650 (OMIM: 606731,616340) oxysterol-binding prot (468 aa)
initn: 3236 init1: 3236 opt: 3236 Z-score: 3484.1 bits: 654.0 E(85289): 2.5e-187
Smith-Waterman score: 3236; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KA0 MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQRE
370 380 390 400 410 420
430 440 450 460
pF1KA0 ARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
430 440 450 460
>>XP_016883654 (OMIM: 606731,616340) PREDICTED: oxystero (480 aa)
initn: 3159 init1: 3159 opt: 3159 Z-score: 3401.1 bits: 638.7 E(85289): 1e-182
Smith-Waterman score: 3202; 97.5% identity (97.5% similar) in 480 aa overlap (1-468:1-480)
10 20 30 40
pF1KA0 MNGEEEFFDAVT------------EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
:::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
430 440 450 460 470 480
>>NP_653081 (OMIM: 606731,616340) oxysterol-binding prot (480 aa)
initn: 3159 init1: 3159 opt: 3159 Z-score: 3401.1 bits: 638.7 E(85289): 1e-182
Smith-Waterman score: 3202; 97.5% identity (97.5% similar) in 480 aa overlap (1-468:1-480)
10 20 30 40
pF1KA0 MNGEEEFFDAVT------------EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
:::::::::::: ::::::::::::::::::::::::::::::::::::
NP_653 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
430 440 450 460 470 480
>>XP_016883656 (OMIM: 606731,616340) PREDICTED: oxystero (388 aa)
initn: 2712 init1: 2712 opt: 2712 Z-score: 2921.7 bits: 549.7 E(85289): 5.3e-156
Smith-Waterman score: 2712; 100.0% identity (100.0% similar) in 388 aa overlap (81-468:1-388)
60 70 80 90 100 110
pF1KA0 SLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASC
::::::::::::::::::::::::::::::
XP_016 MPIAFNEPLSFLQRITEYMEHVYLIHRASC
10 20 30
120 130 140 150 160 170
pF1KA0 QPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 SAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNV
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 IIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKW
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 TECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKL
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 LWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQE
280 290 300 310 320 330
420 430 440 450 460
pF1KA0 KERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
340 350 360 370 380
>>XP_016883653 (OMIM: 606731,616340) PREDICTED: oxystero (516 aa)
initn: 2416 init1: 2416 opt: 2416 Z-score: 2601.6 bits: 490.8 E(85289): 3.6e-138
Smith-Waterman score: 2459; 96.5% identity (96.8% similar) in 376 aa overlap (1-364:1-376)
10 20 30 40
pF1KA0 MNGEEEFFDAVT------------EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
:::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
:::::::::::::::.
XP_016 KLLWRINTRPPNSAQVCVPPWPDVSACSCHTHLWAQPHGSSLSLGPCLPPRLSLLSQSRQ
370 380 390 400 410 420
>>XP_016883652 (OMIM: 606731,616340) PREDICTED: oxystero (516 aa)
initn: 2416 init1: 2416 opt: 2416 Z-score: 2601.6 bits: 490.8 E(85289): 3.6e-138
Smith-Waterman score: 2459; 96.5% identity (96.8% similar) in 376 aa overlap (1-364:1-376)
10 20 30 40
pF1KA0 MNGEEEFFDAVT------------EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
:::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
:::::::::::::::.
XP_016 KLLWRINTRPPNSAQVCVPPWPDVSACSCHTHLWAQPHGSSLSLGPCLPPRLSLLSQSRQ
370 380 390 400 410 420
>>XP_016881022 (OMIM: 606730) PREDICTED: oxysterol-bindi (437 aa)
initn: 2219 init1: 1615 opt: 2226 Z-score: 2398.2 bits: 453.0 E(85289): 7.6e-127
Smith-Waterman score: 2226; 71.4% identity (91.1% similar) in 427 aa overlap (43-468:15-437)
20 30 40 50 60 70
pF1KA0 EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCV
:::.:::::::.:::::.:::.:.::.::.
XP_016 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCI
10 20 30 40
80 90 100 110 120 130
pF1KA0 GLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQ
:.::::::::. ::::::::::.::::::.::::.:: .:.:::: ::::::::::::
XP_016 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 WERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKL
::::::::::::::::::.:.:::::.:::::::::::::::.::::.::.:::::::::
XP_016 WERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 KFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH
:::::::::::.::::::::.::::::::::::::::.:.:::::::::.:::.::.::
XP_016 KFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGD
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA0 KCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRG
::::.::::::::::::::::.::::.:::: .::::::::...::......::.....
XP_016 KCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKN
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA0 DHLRKAKLDEDSGKADSDVADDVPVAQ-ETVQVIPGSKLLWRINTRPPNSAQMYNFTSFT
. .: ... . :. :..:: . :.: .:::: ::::: ::::::::::::::.
XP_016 TEEKK----NSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFA
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA0 VSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAE
. :::.. ::...: ::::::::::.::::..: ::.::.::::::: ::..:.: : .
XP_016 MVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEED
350 360 370 380 390 400
440 450 460
pF1KA0 WQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
:.::::. : :::.:. ::.:.:.:..::. . ::::
XP_016 WKTRWFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY
410 420 430
>>NP_060500 (OMIM: 606730) oxysterol-binding protein-rel (437 aa)
initn: 2219 init1: 1615 opt: 2226 Z-score: 2398.2 bits: 453.0 E(85289): 7.6e-127
Smith-Waterman score: 2226; 71.4% identity (91.1% similar) in 427 aa overlap (43-468:15-437)
20 30 40 50 60 70
pF1KA0 EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCV
:::.:::::::.:::::.:::.:.::.::.
NP_060 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCI
10 20 30 40
80 90 100 110 120 130
pF1KA0 GLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQ
:.::::::::. ::::::::::.::::::.::::.:: .:.:::: ::::::::::::
NP_060 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 WERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKL
::::::::::::::::::.:.:::::.:::::::::::::::.::::.::.:::::::::
NP_060 WERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 KFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH
:::::::::::.::::::::.::::::::::::::::.:.:::::::::.:::.::.::
NP_060 KFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGD
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA0 KCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRG
::::.::::::::::::::::.::::.:::: .::::::::...::......::.....
NP_060 KCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKN
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA0 DHLRKAKLDEDSGKADSDVADDVPVAQ-ETVQVIPGSKLLWRINTRPPNSAQMYNFTSFT
. .: ... . :. :..:: . :.: .:::: ::::: ::::::::::::::.
NP_060 TEEKK----NSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFA
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA0 VSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAE
. :::.. ::...: ::::::::::.::::..: ::.::.::::::: ::..:.: : .
NP_060 MVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEED
350 360 370 380 390 400
440 450 460
pF1KA0 WQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
:.::::. : :::.:. ::.:.:.:..::. . ::::
NP_060 WKTRWFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY
410 420 430
>>XP_016881023 (OMIM: 606730) PREDICTED: oxysterol-bindi (437 aa)
initn: 2219 init1: 1615 opt: 2226 Z-score: 2398.2 bits: 453.0 E(85289): 7.6e-127
Smith-Waterman score: 2226; 71.4% identity (91.1% similar) in 427 aa overlap (43-468:15-437)
20 30 40 50 60 70
pF1KA0 EANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCV
:::.:::::::.:::::.:::.:.::.::.
XP_016 MSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCI
10 20 30 40
80 90 100 110 120 130
pF1KA0 GLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQ
:.::::::::. ::::::::::.::::::.::::.:: .:.:::: ::::::::::::
XP_016 GMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 WERTGKPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKL
::::::::::::::::::.:.:::::.:::::::::::::::.::::.::.:::::::::
XP_016 WERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 KFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH
:::::::::::.::::::::.::::::::::::::::.:.:::::::::.:::.::.::
XP_016 KFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGD
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA0 KCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRG
::::.::::::::::::::::.::::.:::: .::::::::...::......::.....
XP_016 KCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKN
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA0 DHLRKAKLDEDSGKADSDVADDVPVAQ-ETVQVIPGSKLLWRINTRPPNSAQMYNFTSFT
. .: ... . :. :..:: . :.: .:::: ::::: ::::::::::::::.
XP_016 TEEKK----NSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFA
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA0 VSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAE
. :::.. ::...: ::::::::::.::::..: ::.::.::::::: ::..:.: : .
XP_016 MVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEED
350 360 370 380 390 400
440 450 460
pF1KA0 WQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
:.::::. : :::.:. ::.:.:.:..::. . ::::
XP_016 WKTRWFHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY
410 420 430
>>NP_001229437 (OMIM: 606730) oxysterol-binding protein- (568 aa)
initn: 2219 init1: 1615 opt: 2227 Z-score: 2397.7 bits: 453.3 E(85289): 8.1e-127
Smith-Waterman score: 2242; 65.4% identity (87.1% similar) in 482 aa overlap (4-468:91-568)
10 20
pF1KA0 MNGEEEFFDAVTEA-NQKVTGMIDLDTSKN---
:.::.::.... ... . .. :...
NP_001 LSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEE
70 80 90 100 110 120
30 40 50 60 70
pF1KA0 --NRIGKTGERPSQE----------NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELS
...:. .: :.: :::.:::::::.:::::.:::.:.::.::.:.:::
NP_001 EGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELS
130 140 150 160 170 180
80 90 100 110 120 130
pF1KA0 KITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSAVASQWERTG
:::::. ::::::::::.::::::.::::.:: .:.:::: :::::::::::::::::
NP_001 KITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG
190 200 210 220 230 240
140 150 160 170 180 190
pF1KA0 KPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGK
:::::::::::::.:.:::::.:::::::::::::::.::::.::.::::::::::::::
NP_001 KPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGK
250 260 270 280 290 300
200 210 220 230 240 250
pF1KA0 SVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLH
::::::.::::::::.::::::::::::::::.:.:::::::::.:::.::.:: ::::.
NP_001 SVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLN
310 320 330 340 350 360
260 270 280 290 300 310
pF1KA0 FKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRGDHLRK
::::::::::::::::.::::.:::: .::::::::...::......::..... . .:
NP_001 FKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKK
370 380 390 400 410 420
320 330 340 350 360 370
pF1KA0 AKLDEDSGKADSDVADDVPVAQ-ETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNE
... . :. :..:: . :.: .:::: ::::: ::::::::::::::.. :::
NP_001 ----NSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNE
430 440 450 460 470
380 390 400 410 420 430
pF1KA0 LETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTRW
.. ::...: ::::::::::.::::..: ::.::.::::::: ::..:.: : .:.:::
NP_001 VDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRW
480 490 500 510 520 530
440 450 460
pF1KA0 FYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
:. : :::.:. ::.:.:.:..::. . ::::
NP_001 FHQGPNPYNGAQDWIYSGSYWDRNYFNLPDIY
540 550 560
468 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:59:52 2016 done: Fri Nov 4 00:59:53 2016
Total Scan time: 8.920 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]