Result of FASTA (omim) for pF1KA0400
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0400, 1006 aa
  1>>>pF1KA0400 1006 - 1006 aa - 1006 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.6363+/-0.000541; mu= -30.3218+/- 0.034
 mean_var=723.5385+/-152.161, 0's: 0 Z-trim(122.4): 86  B-trim: 2143 in 1/60
 Lambda= 0.047681
 statistics sampled from 40432 (40520) to 40432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.475), width:  16
 Scan time: 16.220

The best scores are:                                      opt bits E(85289)
NP_003878 (OMIM: 603817) arf-GAP with SH3 domain,  (1006) 6734 479.3 4.6e-134
XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP wit (1009) 6718 478.2  1e-133
XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP wit (1017) 6470 461.1 1.4e-128
XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP wit ( 970) 6458 460.3 2.3e-128
XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP wit ( 978) 6458 460.3 2.4e-128
XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP wit (1020) 6454 460.0 2.9e-128
XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP wit ( 891) 5961 426.0 4.3e-118
XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP wit ( 995) 5819 416.3 4.1e-115
NP_001128663 (OMIM: 603817) arf-GAP with SH3 domai ( 961) 5343 383.6 2.9e-105
XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP wit ( 964) 5327 382.5 6.1e-105
XP_011508709 (OMIM: 603817) PREDICTED: arf-GAP wit ( 975) 5063 364.3 1.8e-99
XP_011508710 (OMIM: 603817) PREDICTED: arf-GAP wit ( 959) 5006 360.4 2.7e-98
NP_001234925 (OMIM: 605953) arf-GAP with SH3 domai (1122) 3494 256.4 6.3e-67
NP_060952 (OMIM: 605953) arf-GAP with SH3 domain,  (1129) 3494 256.4 6.3e-67
XP_006716629 (OMIM: 605953) PREDICTED: arf-GAP wit (1075) 3484 255.7 9.7e-67
XP_016868958 (OMIM: 605953) PREDICTED: arf-GAP wit (1072) 3470 254.7 1.9e-66
XP_011515355 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 3459 254.0 3.3e-66
XP_006716627 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 3459 254.0 3.3e-66
XP_006716626 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_011515354 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_005250982 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_016868957 (OMIM: 605953) PREDICTED: arf-GAP wit (1073) 3263 240.5 3.7e-62
XP_016868956 (OMIM: 605953) PREDICTED: arf-GAP wit (1087) 3262 240.4 3.9e-62
XP_006716628 (OMIM: 605953) PREDICTED: arf-GAP wit (1076) 3256 240.0 5.1e-62
XP_016857174 (OMIM: 616594) PREDICTED: arf-GAP wit ( 924) 2660 199.0   1e-49
XP_011540057 (OMIM: 616594) PREDICTED: arf-GAP wit ( 926) 2648 198.2 1.8e-49
NP_060177 (OMIM: 616594) arf-GAP with SH3 domain,  ( 903) 2600 194.8 1.7e-48
XP_016857175 (OMIM: 616594) PREDICTED: arf-GAP wit ( 905) 2588 194.0   3e-48
XP_016857176 (OMIM: 616594) PREDICTED: arf-GAP wit ( 883) 2500 188.0   2e-46
XP_016857177 (OMIM: 616594) PREDICTED: arf-GAP wit ( 793) 2226 169.1 8.6e-41
XP_016857178 (OMIM: 616594) PREDICTED: arf-GAP wit ( 774) 2154 164.1 2.6e-39
NP_001137250 (OMIM: 616594) arf-GAP with SH3 domai ( 894) 2071 158.5 1.5e-37
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778)  505 50.7 3.7e-05
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813)  505 50.7 3.8e-05
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806)  460 47.6 0.00032
XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841)  460 47.6 0.00033
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785)  433 45.7  0.0011
XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820)  433 45.8  0.0012
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462)  409 43.9  0.0024
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527)  409 44.0  0.0026
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580)  409 44.0  0.0028
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580)  409 44.0  0.0028
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565)  405 43.7  0.0034
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  410 44.2  0.0034
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  410 44.2  0.0034
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  410 44.2  0.0034
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630)  405 43.7  0.0037
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683)  405 43.8  0.0039
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK  ( 911)  405 43.9  0.0049
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882)  390 42.8  0.0098


>>NP_003878 (OMIM: 603817) arf-GAP with SH3 domain, ANK   (1006 aa)
 initn: 6734 init1: 6734 opt: 6734  Z-score: 2527.8  bits: 479.3 E(85289): 4.6e-134
Smith-Waterman score: 6734; 100.0% identity (100.0% similar) in 1006 aa overlap (1-1006:1-1006)

               10        20        30        40        50        60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
              910       920       930       940       950       960

              970       980       990      1000      
pF1KA0 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
              970       980       990      1000      

>>XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP with SH  (1009 aa)
 initn: 4929 init1: 4929 opt: 6718  Z-score: 2521.8  bits: 478.2 E(85289): 1e-133
Smith-Waterman score: 6718; 99.7% identity (99.7% similar) in 1009 aa overlap (1-1006:1-1009)

               10        20        30        40        50        60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
              190       200       210       220       230       240

              250       260       270       280          290       
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQ
       :::::::::::::::::::::::::::::::::::::::::::   ::::::::::::::
XP_006 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQ
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KA0 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KA0 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KA0 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KA0 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KA0 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KA0 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
              610       620       630       640       650       660

       660       670       680       690       700       710       
pF1KA0 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
              670       680       690       700       710       720

       720       730       740       750       760       770       
pF1KA0 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
              730       740       750       760       770       780

       780       790       800       810       820       830       
pF1KA0 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
              790       800       810       820       830       840

       840       850       860       870       880       890       
pF1KA0 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
              850       860       870       880       890       900

       900       910       920       930       940       950       
pF1KA0 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
              910       920       930       940       950       960

       960       970       980       990      1000      
pF1KA0 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
              970       980       990      1000         

>>XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP with SH  (1017 aa)
 initn: 6470 init1: 6470 opt: 6470  Z-score: 2429.6  bits: 461.1 E(85289): 1.4e-128
Smith-Waterman score: 6702; 98.9% identity (98.9% similar) in 1017 aa overlap (1-1006:1-1017)

               10        20        30        40                    
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
              190       200       210       220       230       240

     230       240       250       260       270       280         
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQ
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 STAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKL
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 NLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDN
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 TGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVH
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 YSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAK
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETAL
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 HLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEI
              610       620       630       640       650       660

     650       660       670       680       690       700         
pF1KA0 ANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKL
              670       680       690       700       710       720

     710       720       730       740       750       760         
pF1KA0 QPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSG
              730       740       750       760       770       780

     770       780       790       800       810       820         
pF1KA0 SPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHP
              790       800       810       820       830       840

     830       840       850       860       870       880         
pF1KA0 PLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQ
              850       860       870       880       890       900

     890       900       910       920       930       940         
pF1KA0 KKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRV
              910       920       930       940       950       960

     950       960       970       980       990      1000      
pF1KA0 KALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
              970       980       990      1000      1010       

>>XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP with SH  (970 aa)
 initn: 4929 init1: 4929 opt: 6458  Z-score: 2425.4  bits: 460.3 E(85289): 2.3e-128
Smith-Waterman score: 6458; 99.7% identity (99.7% similar) in 968 aa overlap (42-1006:3-970)

              20        30        40        50        60        70 
pF1KA0 AETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVEN
                                     ::::::::::::::::::::::::::::::
XP_006                             MLEALDVDRMVLYKMKKSVKAINSSGLAHVEN
                                           10        20        30  

              80        90       100       110       120       130 
pF1KA0 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
             40        50        60        70        80        90  

             140       150       160       170       180       190 
pF1KA0 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
            100       110       120       130       140       150  

             200       210       220       230       240       250 
pF1KA0 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
            160       170       180       190       200       210  

             260       270       280          290       300        
pF1KA0 LHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTER
       ::::::::::::::::::::::::::::::::   :::::::::::::::::::::::::
XP_006 LHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTER
            220       230       240       250       260       270  

      310       320       330       340       350       360        
pF1KA0 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
            280       290       300       310       320       330  

      370       380       390       400       410       420        
pF1KA0 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
            340       350       360       370       380       390  

      430       440       450       460       470       480        
pF1KA0 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
            400       410       420       430       440       450  

      490       500       510       520       530       540        
pF1KA0 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
            460       470       480       490       500       510  

      550       560       570       580       590       600        
pF1KA0 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
            520       530       540       550       560       570  

      610       620       630       640       650       660        
pF1KA0 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
            580       590       600       610       620       630  

      670       680       690       700       710       720        
pF1KA0 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
            640       650       660       670       680       690  

      730       740       750       760       770       780        
pF1KA0 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
            700       710       720       730       740       750  

      790       800       810       820       830       840        
pF1KA0 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
            760       770       780       790       800       810  

      850       860       870       880       890       900        
pF1KA0 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
            820       830       840       850       860       870  

      910       920       930       940       950       960        
pF1KA0 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
            880       890       900       910       920       930  

      970       980       990      1000      
pF1KA0 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::
XP_006 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
            940       950       960       970

>>XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP with SH  (978 aa)
 initn: 4929 init1: 4929 opt: 6458  Z-score: 2425.4  bits: 460.3 E(85289): 2.4e-128
Smith-Waterman score: 6458; 99.7% identity (99.7% similar) in 968 aa overlap (42-1006:11-978)

              20        30        40        50        60        70 
pF1KA0 AETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVEN
                                     ::::::::::::::::::::::::::::::
XP_011                     MISVPIQKSPEALDVDRMVLYKMKKSVKAINSSGLAHVEN
                                   10        20        30        40

              80        90       100       110       120       130 
pF1KA0 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
               50        60        70        80        90       100

             140       150       160       170       180       190 
pF1KA0 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
              110       120       130       140       150       160

             200       210       220       230       240       250 
pF1KA0 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
              170       180       190       200       210       220

             260       270       280          290       300        
pF1KA0 LHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTER
       ::::::::::::::::::::::::::::::::   :::::::::::::::::::::::::
XP_011 LHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTER
              230       240       250       260       270       280

      310       320       330       340       350       360        
pF1KA0 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
              290       300       310       320       330       340

      370       380       390       400       410       420        
pF1KA0 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
              350       360       370       380       390       400

      430       440       450       460       470       480        
pF1KA0 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
              410       420       430       440       450       460

      490       500       510       520       530       540        
pF1KA0 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
              470       480       490       500       510       520

      550       560       570       580       590       600        
pF1KA0 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
              530       540       550       560       570       580

      610       620       630       640       650       660        
pF1KA0 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
              590       600       610       620       630       640

      670       680       690       700       710       720        
pF1KA0 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
              650       660       670       680       690       700

      730       740       750       760       770       780        
pF1KA0 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
              710       720       730       740       750       760

      790       800       810       820       830       840        
pF1KA0 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
              770       780       790       800       810       820

      850       860       870       880       890       900        
pF1KA0 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
              830       840       850       860       870       880

      910       920       930       940       950       960        
pF1KA0 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
              890       900       910       920       930       940

      970       980       990      1000      
pF1KA0 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::
XP_011 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
              950       960       970        

>>XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP with SH  (1020 aa)
 initn: 5181 init1: 4929 opt: 6454  Z-score: 2423.6  bits: 460.0 E(85289): 2.9e-128
Smith-Waterman score: 6686; 98.6% identity (98.6% similar) in 1020 aa overlap (1-1006:1-1020)

               10        20        30        40                    
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
              190       200       210       220       230       240

     230       240       250       260       270       280         
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::   :::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQ
              250       260       270       280       290       300

        290       300       310       320       330       340      
pF1KA0 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
              310       320       330       340       350       360

        350       360       370       380       390       400      
pF1KA0 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
              370       380       390       400       410       420

        410       420       430       440       450       460      
pF1KA0 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
              430       440       450       460       470       480

        470       480       490       500       510       520      
pF1KA0 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
              490       500       510       520       530       540

        530       540       550       560       570       580      
pF1KA0 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
              550       560       570       580       590       600

        590       600       610       620       630       640      
pF1KA0 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
              610       620       630       640       650       660

        650       660       670       680       690       700      
pF1KA0 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
              670       680       690       700       710       720

        710       720       730       740       750       760      
pF1KA0 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
              730       740       750       760       770       780

        770       780       790       800       810       820      
pF1KA0 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
              790       800       810       820       830       840

        830       840       850       860       870       880      
pF1KA0 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
              850       860       870       880       890       900

        890       900       910       920       930       940      
pF1KA0 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
              910       920       930       940       950       960

        950       960       970       980       990      1000      
pF1KA0 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
              970       980       990      1000      1010      1020

>>XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP with SH  (891 aa)
 initn: 4929 init1: 4929 opt: 5961  Z-score: 2241.2  bits: 426.0 E(85289): 4.3e-118
Smith-Waterman score: 5961; 99.7% identity (99.7% similar) in 891 aa overlap (119-1006:1-891)

       90       100       110       120       130       140        
pF1KA0 RDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDK
                                     ::::::::::::::::::::::::::::::
XP_011                               MNNIISFPLDSLLKGDLKGVKGDLKKPFDK
                                             10        20        30

      150       160       170       180       190       200        
pF1KA0 AWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEI
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KA0 KIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQ
              100       110       120       130       140       150

      270       280          290       300       310       320     
pF1KA0 LRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQK
       :::::::::::::::   ::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQK
              160       170       180       190       200       210

         330       340       350       360       370       380     
pF1KA0 RKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQEC
              220       230       240       250       260       270

         390       400       410       420       430       440     
pF1KA0 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPT
              280       290       300       310       320       330

         450       460       470       480       490       500     
pF1KA0 WLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCL
              340       350       360       370       380       390

         510       520       530       540       550       560     
pF1KA0 PAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQA
              400       410       420       430       440       450

         570       580       590       600       610       620     
pF1KA0 YADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTAL
              460       470       480       490       500       510

         630       640       650       660       670       680     
pF1KA0 HYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHV
              520       530       540       550       560       570

         690       700       710       720       730       740     
pF1KA0 HVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANL
              580       590       600       610       620       630

         750       760       770       780       790       800     
pF1KA0 AKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLW
              640       650       660       670       680       690

         810       820       830       840       850       860     
pF1KA0 KTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSK
              700       710       720       730       740       750

         870       880       890       900       910       920     
pF1KA0 PAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSN
              760       770       780       790       800       810

         930       940       950       960       970       980     
pF1KA0 AMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGH
              820       830       840       850       860       870

         990      1000      
pF1KA0 IDGDPGRKGAFPVSFVHFIAD
       :::::::::::::::::::::
XP_011 IDGDPGRKGAFPVSFVHFIAD
              880       890 

>>XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP with SH  (995 aa)
 initn: 5389 init1: 4929 opt: 5819  Z-score: 2187.7  bits: 416.3 E(85289): 4.1e-115
Smith-Waterman score: 6465; 96.2% identity (96.2% similar) in 1020 aa overlap (1-1006:1-995)

               10        20        30        40                    
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
       ::::::                         :::::::::::::::::::::::::::::
XP_011 ALFKNL-------------------------DLKKPFDKAWKDYETKITKIEKEKKEHAK
                                       130       140       150     

     170       180       190       200       210       220         
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
         160       170       180       190       200       210     

     230       240       250       260       270       280         
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::   :::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQ
         220       230       240       250       260       270     

        290       300       310       320       330       340      
pF1KA0 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
         280       290       300       310       320       330     

        350       360       370       380       390       400      
pF1KA0 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
         340       350       360       370       380       390     

        410       420       430       440       450       460      
pF1KA0 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
         400       410       420       430       440       450     

        470       480       490       500       510       520      
pF1KA0 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
         460       470       480       490       500       510     

        530       540       550       560       570       580      
pF1KA0 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
         520       530       540       550       560       570     

        590       600       610       620       630       640      
pF1KA0 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
         580       590       600       610       620       630     

        650       660       670       680       690       700      
pF1KA0 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
         640       650       660       670       680       690     

        710       720       730       740       750       760      
pF1KA0 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
         700       710       720       730       740       750     

        770       780       790       800       810       820      
pF1KA0 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
         760       770       780       790       800       810     

        830       840       850       860       870       880      
pF1KA0 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
         820       830       840       850       860       870     

        890       900       910       920       930       940      
pF1KA0 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
         880       890       900       910       920       930     

        950       960       970       980       990      1000      
pF1KA0 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
         940       950       960       970       980       990     

>>NP_001128663 (OMIM: 603817) arf-GAP with SH3 domain, A  (961 aa)
 initn: 5286 init1: 5286 opt: 5343  Z-score: 2010.9  bits: 383.6 E(85289): 2.9e-105
Smith-Waterman score: 6332; 95.4% identity (95.5% similar) in 1006 aa overlap (1-1006:1-961)

               10        20        30        40        50        60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
       ::::::::::::::                                             .
NP_001 TTSAPPLPPRNVGK---------------------------------------------D
              790                                                  

              850       860       870       880       890       900
pF1KA0 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
         800       810       820       830       840       850     

              910       920       930       940       950       960
pF1KA0 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
         860       870       880       890       900       910     

              970       980       990      1000      
pF1KA0 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
         920       930       940       950       960 

>>XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP with SH  (964 aa)
 initn: 5339 init1: 3481 opt: 5327  Z-score: 2005.0  bits: 382.5 E(85289): 6.1e-105
Smith-Waterman score: 6316; 95.1% identity (95.2% similar) in 1009 aa overlap (1-1006:1-964)

               10        20        30        40        50        60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
              190       200       210       220       230       240

              250       260       270       280          290       
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQ
       :::::::::::::::::::::::::::::::::::::::::::   ::::::::::::::
XP_006 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQ
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KA0 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KA0 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KA0 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KA0 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KA0 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KA0 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
              610       620       630       640       650       660

       660       670       680       690       700       710       
pF1KA0 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
              670       680       690       700       710       720

       720       730       740       750       760       770       
pF1KA0 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
              730       740       750       760       770       780

       780       790       800       810       820       830       
pF1KA0 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
       :::::::::::::::::                                           
XP_006 APSTTSAPPLPPRNVGK-------------------------------------------
              790                                                  

       840       850       860       870       880       890       
pF1KA0 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
         .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 --DPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
         800       810       820       830       840       850     

       900       910       920       930       940       950       
pF1KA0 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
         860       870       880       890       900       910     

       960       970       980       990      1000      
pF1KA0 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
         920       930       940       950       960    




1006 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 00:39:32 2016 done: Fri Nov  4 00:39:34 2016
 Total Scan time: 16.220 Total Display time:  0.430

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com