Result of FASTA (omim) for
pF1KB4613
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4613, 265 aa
1>>>pF1KB4613 265 - 265 aa - 265 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4757+/-0.000295; mu= 12.5668+/- 0.019
mean_var=162.9181+/-32.940, 0's: 0 Z-trim(122.8): 71 B-trim: 67 in 1/54
Lambda= 0.100482
statistics sampled from 41313 (41413) to 41313 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.486), width: 16
Scan time: 5.920
The best scores are: opt bits E(85289)
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 1424 217.6 3.1e-56
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 1163 179.8 8.3e-45
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 1058 164.4 2.6e-40
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 1052 163.7 5.4e-40
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 693 111.6 2.3e-24
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 693 111.6 2.3e-24
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 693 111.6 2.3e-24
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 693 111.6 2.4e-24
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 693 111.6 2.4e-24
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 693 111.6 2.5e-24
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 693 111.6 2.5e-24
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 688 110.8 3.6e-24
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 691 111.6 4e-24
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 691 111.6 4.1e-24
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 691 111.6 4.3e-24
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 691 111.6 4.3e-24
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 691 111.6 4.3e-24
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 691 111.6 4.3e-24
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 635 103.1 7.4e-22
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 630 102.4 1.2e-21
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 626 101.7 1.5e-21
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 613 99.8 5.9e-21
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 596 97.4 3.4e-20
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 515 85.8 1.4e-16
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 512 85.3 1.6e-16
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 499 83.1 4.2e-16
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 499 83.1 4.2e-16
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 490 82.2 1.7e-15
NP_001234923 (OMIM: 164176) POU domain, class 2, t ( 400) 422 72.3 1.6e-12
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 422 72.4 1.7e-12
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 422 72.4 1.8e-12
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 422 72.5 2e-12
XP_016882382 (OMIM: 164176) PREDICTED: POU domain, ( 608) 422 72.5 2e-12
XP_016882380 (OMIM: 164176) PREDICTED: POU domain, ( 707) 422 72.6 2.3e-12
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 413 71.1 4.3e-12
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 413 71.1 4.3e-12
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 413 71.1 4.5e-12
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 413 71.1 4.7e-12
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 413 71.2 5e-12
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 413 71.2 5e-12
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 413 71.2 5e-12
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 413 71.2 5.1e-12
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 413 71.3 5.5e-12
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 413 71.3 5.6e-12
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 413 71.3 5.6e-12
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 413 71.3 5.6e-12
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 413 71.3 5.6e-12
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 413 71.3 5.6e-12
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 413 71.3 5.7e-12
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 413 71.3 5.7e-12
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 1382 init1: 1382 opt: 1424 Z-score: 1130.5 bits: 217.6 E(85289): 3.1e-56
Smith-Waterman score: 1425; 79.6% identity (88.0% similar) in 275 aa overlap (2-265:170-443)
10 20
pF1KB4 MATAASNHY--SLLTSSASIVHAEPP---GG
..::. : :. .:........: .:
NP_005 QQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVNG
140 150 160 170 180 190
30 40 50 60 70 80
pF1KB4 MQQGAGG-----YREAQSLVQGDYGALQSNGHPLSHAHQWITAPPP-QGPPGHPGAHHDP
: :::: .... .. . . . :: :: :: ::: :::::::::::::
NP_005 ML-GAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHDP
200 210 220 230 240 250
90 100 110 120 130 140
pF1KB4 HSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSF
260 270 280 290 300 310
150 160 170 180 190 200
pF1KB4 KNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPK
320 330 340 350 360 370
210 220 230 240 250 260
pF1KB4 PSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGV
380 390 400 410 420 430
pF1KB4 QTPVQ
:::::
NP_005 QTPVQ
440
>--
initn: 446 init1: 430 opt: 437 Z-score: 357.2 bits: 74.5 E(85289): 3.7e-13
Smith-Waterman score: 437; 89.3% identity (89.3% similar) in 75 aa overlap (1-75:1-75)
10 20 30 40 50 60
pF1KB4 MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 WITAPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTL
:::: : : :
NP_005 WITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRGDELHG
70 80 90 100 110 120
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 1218 init1: 1078 opt: 1163 Z-score: 925.4 bits: 179.8 E(85289): 8.3e-45
Smith-Waterman score: 1216; 74.4% identity (79.6% similar) in 270 aa overlap (18-265:233-500)
10 20 30 40
pF1KB4 MATAASNHYSLLTSSASIVHAEP-PGGMQQGAGGYREA---QSLVQG
.. : : ::: :::: .. .::.:
NP_006 AAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRG
210 220 230 240 250 260
50 60 70 80 90
pF1KB4 DYGALQSNGHPLSHAHQWITAPP-P---QGPPGH--------PGAH-HDPHSDEDTPTSD
: : . : : :. :: : :::: : :: . :::::::::::::
NP_006 DTPELAEHHH--HHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSD
270 280 290 300 310 320
100 110 120 130 140 150
pF1KB4 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL
330 340 350 360 370 380
160 170 180 190 200 210
pF1KB4 NKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLA
::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.::
NP_006 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLA
390 400 410 420 430 440
220 230 240 250 260
pF1KB4 DSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGG----SRDTPP-HHGVQTPVQ
:::::::::::::::::::::::::::: .:::. : :::: :::.:: ::
NP_006 DSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ
450 460 470 480 490 500
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 1141 init1: 1024 opt: 1058 Z-score: 844.8 bits: 164.4 E(85289): 2.6e-40
Smith-Waterman score: 1058; 77.2% identity (84.9% similar) in 219 aa overlap (46-257:143-359)
20 30 40 50 60 70
pF1KB4 ASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNG--HPLSHAHQWITAPPPQGPPGH
: :. .: : . : : . :: :
NP_000 AWGASPAPNPSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASAQSLHPVLREPPDH
120 130 140 150 160 170
80 90 100 110 120 130
pF1KB4 P--GAHH-DPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTI
:.:: . ::::.:::::.:::::::::::::::::::::::::::::::::::::::
NP_000 GELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTI
180 190 200 210 220 230
140 150 160 170 180 190
pF1KB4 CRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGA
::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::.
NP_000 CRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGV
240 250 260 270 280 290
200 210 220 230 240 250
pF1KB4 LESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGG
::.::::::::.::::.::::::::::::::::::::::::::::::: : ..::.
NP_000 LETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQP--HEVYSH
300 310 320 330 340 350
260
pF1KB4 S--RDTPPHHGVQTPVQ
. :: :
NP_000 TVKTDTSCHDL
360
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 1086 init1: 995 opt: 1052 Z-score: 839.0 bits: 163.7 E(85289): 5.4e-40
Smith-Waterman score: 1059; 66.5% identity (75.4% similar) in 272 aa overlap (20-263:161-427)
10 20 30 40
pF1KB4 MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGA--
.: ::: :.:: : :. : ::
NP_002 GSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGG---GGGGL--AGMLAAGGGGAGP
140 150 160 170 180
50 60 70 80
pF1KB4 -LQSNGHPLSHAHQWITAPPPQ-GPPGHP------------GAHHDP-----------HS
:. : .: : .:::. : :: .:: : ::
NP_002 GLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHS
190 200 210 220 230 240
90 100 110 120 130 140
pF1KB4 DEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN
:::.:.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN
250 260 270 280 290 300
150 160 170 180 190 200
pF1KB4 MCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPS
::::::::::::::.::::::::..::::::::::::::::::.::::::::::::::::
NP_002 MCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPS
310 320 330 340 350 360
210 220 230 240 250 260
pF1KB4 AQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGT-LPGAEDVYGGSRDTPPHHGVQ
:.:::.:::::::::::::::::::::::::::: .:. : .:::. .. : :..
NP_002 AHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGAS
370 380 390 400 410 420
pF1KB4 TPVQ
:
NP_002 PPSAPPPPPPAALHHHHHHTLPGSVQ
430 440 450
>>XP_011541045 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 704 init1: 388 opt: 693 Z-score: 558.3 bits: 111.6 E(85289): 2.3e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:71-326)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
110 120 130 140 150
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
XP_011 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
160 170 180 190 200 210
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
XP_011 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
XP_011 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
280 290 300 310 320 330
XP_011 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
340 350 360 370 380 390
>>XP_011541043 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 704 init1: 388 opt: 693 Z-score: 558.3 bits: 111.6 E(85289): 2.3e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:71-326)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
110 120 130 140 150
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
XP_011 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
160 170 180 190 200 210
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
XP_011 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
XP_011 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
280 290 300 310 320 330
XP_011 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
340 350 360 370 380 390
>>XP_011541044 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 704 init1: 388 opt: 693 Z-score: 558.3 bits: 111.6 E(85289): 2.3e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:71-326)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
110 120 130 140 150
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
XP_011 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
160 170 180 190 200 210
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
XP_011 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
XP_011 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
280 290 300 310 320 330
XP_011 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
340 350 360 370 380 390
>>XP_011541042 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 704 init1: 388 opt: 693 Z-score: 557.9 bits: 111.6 E(85289): 2.4e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:100-355)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
XP_011 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
190 200 210 220 230 240
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
XP_011 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
250 260 270 280 290 300
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
XP_011 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
310 320 330 340 350 360
XP_011 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
370 380 390 400 410 420
>>XP_011541041 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 704 init1: 388 opt: 693 Z-score: 557.9 bits: 111.6 E(85289): 2.4e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:100-355)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
XP_011 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
190 200 210 220 230 240
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
XP_011 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
250 260 270 280 290 300
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
XP_011 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
310 320 330 340 350 360
XP_011 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
370 380 390 400 410 420
>>NP_055167 (OMIM: 607394) POU domain, class 2, transcri (436 aa)
initn: 704 init1: 388 opt: 693 Z-score: 557.9 bits: 111.6 E(85289): 2.5e-24
Smith-Waterman score: 693; 50.0% identity (69.6% similar) in 260 aa overlap (11-256:104-359)
10 20 30
pF1KB4 MATAASNHYSLLTSSASIVHAEPPG--GMQQGAGGYREAQ
: . : .. :: :.: . . . :
NP_055 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB4 S---LVQGDYG-ALQSNGHPLSHAHQWITAPPPQGPPGHPGAHHDPHSD-EDTPTS-DDL
: : : : : :. ::: . . : .. : .: : : : :.. ..:
NP_055 SGLLLPQTGPGLASQAFGHPGLPGSS--LEPHLEASQHLPVPKHLPSSGGADEPSDLEEL
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB4 EQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNK
:.::: ::::::::::::.:::::.: :::: :::::: :::::.:::::::::::::.:
NP_055 EKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK
200 210 220 230 240 250
160 170 180 190 200
pF1KB4 WLEEADSSSG-----SPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI
::..:.:: . .:.: ... :::::::::::.... .::..: ::::..::
NP_055 WLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEI
260 270 280 290 300 310
210 220 230 240 250 260
pF1KB4 TSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
. .:..:..::::::::::::::::::.. : .: : ::. :: . :
NP_055 SMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVYN-SRLVSPSGSLGPLSVP
320 330 340 350 360
NP_055 PVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRW
370 380 390 400 410 420
265 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:38:19 2016 done: Thu Nov 3 21:38:20 2016
Total Scan time: 5.920 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]