Result of FASTA (omim) for pF1KB3619
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3619, 902 aa
  1>>>pF1KB3619 902 - 902 aa - 902 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5140+/-0.000419; mu= 15.6130+/- 0.026
 mean_var=113.1426+/-23.254, 0's: 0 Z-trim(114.7): 195  B-trim: 684 in 1/54
 Lambda= 0.120576
 statistics sampled from 24407 (24654) to 24407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.289), width:  16
 Scan time: 13.490

The best scores are:                                      opt bits E(85289)
NP_001305713 (OMIM: 300535,300555,309000) inositol ( 902) 6123 1077.0       0
NP_000267 (OMIM: 300535,300555,309000) inositol po ( 901) 6101 1073.1       0
NP_001578 (OMIM: 300535,300555,309000) inositol po ( 893) 6025 1059.9       0
XP_011529646 (OMIM: 300535,300555,309000) PREDICTE ( 853) 5579 982.3       0
XP_011529647 (OMIM: 300535,300555,309000) PREDICTE ( 853) 5579 982.3       0
XP_016885043 (OMIM: 300535,300555,309000) PREDICTE ( 831) 5292 932.4       0
XP_005262479 (OMIM: 300535,300555,309000) PREDICTE ( 744) 5055 891.1       0
NP_001284363 (OMIM: 147264) type II inositol 1,4,5 ( 749) 2078 373.3 2.5e-102
XP_016856696 (OMIM: 147264) PREDICTED: type II ino ( 794) 2078 373.3 2.6e-102
XP_016856695 (OMIM: 147264) PREDICTED: type II ino ( 823) 2078 373.3 2.7e-102
XP_006710684 (OMIM: 147264) PREDICTED: type II ino ( 848) 2078 373.3 2.8e-102
NP_005531 (OMIM: 147264) type II inositol 1,4,5-tr ( 913) 2078 373.3 2.9e-102
XP_011539694 (OMIM: 147264) PREDICTED: type II ino ( 720) 2074 372.5  4e-102
XP_011539695 (OMIM: 147264) PREDICTED: type II ino ( 720) 2074 372.5  4e-102
XP_016856698 (OMIM: 147264) PREDICTED: type II ino ( 693) 2073 372.4 4.3e-102
XP_016856697 (OMIM: 147264) PREDICTED: type II ino ( 693) 2073 372.4 4.3e-102
XP_005267256 (OMIM: 609410) PREDICTED: synaptojani (1113)  663 127.2 4.3e-28
XP_016866895 (OMIM: 609410) PREDICTED: synaptojani (1113)  663 127.2 4.3e-28
XP_011534530 (OMIM: 609410) PREDICTED: synaptojani (1113)  663 127.2 4.3e-28
XP_011534529 (OMIM: 609410) PREDICTED: synaptojani (1158)  663 127.2 4.4e-28
XP_005267255 (OMIM: 609410) PREDICTED: synaptojani (1165)  663 127.2 4.5e-28
XP_011534528 (OMIM: 609410) PREDICTED: synaptojani (1165)  663 127.2 4.5e-28
XP_011534532 (OMIM: 609410) PREDICTED: synaptojani (1243)  663 127.3 4.7e-28
NP_001171559 (OMIM: 609410) synaptojanin-2 isoform (1259)  663 127.3 4.7e-28
XP_011534527 (OMIM: 609410) PREDICTED: synaptojani (1259)  663 127.3 4.7e-28
XP_006715655 (OMIM: 609410) PREDICTED: synaptojani (1288)  663 127.3 4.8e-28
XP_011534526 (OMIM: 609410) PREDICTED: synaptojani (1451)  663 127.3 5.3e-28
NP_003889 (OMIM: 609410) synaptojanin-2 isoform 1  (1496)  663 127.3 5.4e-28
XP_016883993 (OMIM: 604297,615530) PREDICTED: syna (1269)  626 120.8 4.1e-26
XP_016883992 (OMIM: 604297,615530) PREDICTED: syna (1282)  626 120.8 4.2e-26
XP_016883991 (OMIM: 604297,615530) PREDICTED: syna (1294)  626 120.8 4.2e-26
NP_001153774 (OMIM: 604297,615530) synaptojanin-1  (1295)  626 120.8 4.2e-26
XP_016883994 (OMIM: 604297,615530) PREDICTED: syna (1303)  626 120.8 4.2e-26
XP_016883990 (OMIM: 604297,615530) PREDICTED: syna (1310)  626 120.8 4.2e-26
XP_016883989 (OMIM: 604297,615530) PREDICTED: syna (1311)  626 120.8 4.2e-26
NP_982271 (OMIM: 604297,615530) synaptojanin-1 iso (1350)  626 120.9 4.3e-26
NP_001153778 (OMIM: 604297,615530) synaptojanin-1  (1526)  626 120.9 4.8e-26
XP_016883987 (OMIM: 604297,615530) PREDICTED: syna (1531)  626 120.9 4.8e-26
XP_016883985 (OMIM: 604297,615530) PREDICTED: syna (1544)  626 120.9 4.8e-26
XP_016883983 (OMIM: 604297,615530) PREDICTED: syna (1557)  626 120.9 4.8e-26
XP_016883988 (OMIM: 604297,615530) PREDICTED: syna (1565)  626 120.9 4.9e-26
XP_016883986 (OMIM: 604297,615530) PREDICTED: syna (1596)  626 120.9 4.9e-26
XP_016883984 (OMIM: 604297,615530) PREDICTED: syna (1607)  626 120.9   5e-26
NP_003886 (OMIM: 604297,615530) synaptojanin-1 iso (1612)  626 120.9   5e-26
XP_005267257 (OMIM: 609410) PREDICTED: synaptojani ( 909)  612 118.3 1.7e-25
XP_011543302 (OMIM: 258480,600829) PREDICTED: phos (1206)  563 109.9 7.9e-23
XP_011543301 (OMIM: 258480,600829) PREDICTED: phos (1258)  563 109.9 8.2e-23
NP_001558 (OMIM: 258480,600829) phosphatidylinosit (1258)  563 109.9 8.2e-23
XP_016873162 (OMIM: 258480,600829) PREDICTED: phos (1270)  563 109.9 8.2e-23
XP_005274036 (OMIM: 258480,600829) PREDICTED: phos (1280)  563 109.9 8.3e-23


>>NP_001305713 (OMIM: 300535,300555,309000) inositol pol  (902 aa)
 initn: 6123 init1: 6123 opt: 6123  Z-score: 5759.7  bits: 1077.0 E(85289):    0
Smith-Waterman score: 6123; 100.0% identity (100.0% similar) in 902 aa overlap (1-902:1-902)

               10        20        30        40        50        60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
              850       860       870       880       890       900

         
pF1KB3 ED
       ::
NP_001 ED
         

>>NP_000267 (OMIM: 300535,300555,309000) inositol polyph  (901 aa)
 initn: 6099 init1: 6020 opt: 6101  Z-score: 5739.1  bits: 1073.1 E(85289):    0
Smith-Waterman score: 6101; 99.9% identity (99.9% similar) in 902 aa overlap (1-902:1-901)

               10        20        30        40        50        60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
       ::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
     840       850       860       870       880       890         

         
pF1KB3 ED
       ::
NP_000 ED
     900 

>>NP_001578 (OMIM: 300535,300555,309000) inositol polyph  (893 aa)
 initn: 4789 init1: 4710 opt: 6025  Z-score: 5667.7  bits: 1059.9 E(85289):    0
Smith-Waterman score: 6025; 99.0% identity (99.0% similar) in 902 aa overlap (1-902:1-893)

               10        20        30        40        50        60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
       ::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
       :::::::::::::::::::::::::::::::::::::::::::::::        :::::
NP_001 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLE--------KSLLQ
     660       670       680       690       700               710 

              730       740       750       760       770       780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
             720       730       740       750       760       770 

              790       800       810       820       830       840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
             780       790       800       810       820       830 

              850       860       870       880       890       900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
             840       850       860       870       880       890 

         
pF1KB3 ED
       ::
NP_001 ED
         

>>XP_011529646 (OMIM: 300535,300555,309000) PREDICTED: i  (853 aa)
 initn: 5579 init1: 5579 opt: 5579  Z-score: 5248.6  bits: 982.3 E(85289):    0
Smith-Waterman score: 5579; 100.0% identity (100.0% similar) in 821 aa overlap (82-902:33-853)

              60        70        80        90       100       110 
pF1KB3 HVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
                                     ::::::::::::::::::::::::::::::
XP_011 WRLLVNLKQFQRDPKLMAGDRVERKSYEPGGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
             10        20        30        40        50        60  

             120       130       140       150       160       170 
pF1KB3 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
             70        80        90       100       110       120  

             180       190       200       210       220       230 
pF1KB3 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
            130       140       150       160       170       180  

             240       250       260       270       280       290 
pF1KB3 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
            190       200       210       220       230       240  

             300       310       320       330       340       350 
pF1KB3 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
            250       260       270       280       290       300  

             360       370       380       390       400       410 
pF1KB3 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
            310       320       330       340       350       360  

             420       430       440       450       460       470 
pF1KB3 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
            370       380       390       400       410       420  

             480       490       500       510       520       530 
pF1KB3 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
            430       440       450       460       470       480  

             540       550       560       570       580       590 
pF1KB3 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
            490       500       510       520       530       540  

             600       610       620       630       640       650 
pF1KB3 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
            550       560       570       580       590       600  

             660       670       680       690       700       710 
pF1KB3 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
            610       620       630       640       650       660  

             720       730       740       750       760       770 
pF1KB3 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
            670       680       690       700       710       720  

             780       790       800       810       820       830 
pF1KB3 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
            730       740       750       760       770       780  

             840       850       860       870       880       890 
pF1KB3 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
            790       800       810       820       830       840  

             900  
pF1KB3 LLGFLLGSEED
       :::::::::::
XP_011 LLGFLLGSEED
            850   

>>XP_011529647 (OMIM: 300535,300555,309000) PREDICTED: i  (853 aa)
 initn: 5579 init1: 5579 opt: 5579  Z-score: 5248.6  bits: 982.3 E(85289):    0
Smith-Waterman score: 5579; 100.0% identity (100.0% similar) in 821 aa overlap (82-902:33-853)

              60        70        80        90       100       110 
pF1KB3 HVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
                                     ::::::::::::::::::::::::::::::
XP_011 WRLLVNLKQFQRDPKLMAGDRVERKSYEPGGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
             10        20        30        40        50        60  

             120       130       140       150       160       170 
pF1KB3 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
             70        80        90       100       110       120  

             180       190       200       210       220       230 
pF1KB3 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
            130       140       150       160       170       180  

             240       250       260       270       280       290 
pF1KB3 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
            190       200       210       220       230       240  

             300       310       320       330       340       350 
pF1KB3 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
            250       260       270       280       290       300  

             360       370       380       390       400       410 
pF1KB3 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
            310       320       330       340       350       360  

             420       430       440       450       460       470 
pF1KB3 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
            370       380       390       400       410       420  

             480       490       500       510       520       530 
pF1KB3 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
            430       440       450       460       470       480  

             540       550       560       570       580       590 
pF1KB3 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
            490       500       510       520       530       540  

             600       610       620       630       640       650 
pF1KB3 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
            550       560       570       580       590       600  

             660       670       680       690       700       710 
pF1KB3 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
            610       620       630       640       650       660  

             720       730       740       750       760       770 
pF1KB3 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
            670       680       690       700       710       720  

             780       790       800       810       820       830 
pF1KB3 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
            730       740       750       760       770       780  

             840       850       860       870       880       890 
pF1KB3 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
            790       800       810       820       830       840  

             900  
pF1KB3 LLGFLLGSEED
       :::::::::::
XP_011 LLGFLLGSEED
            850   

>>XP_016885043 (OMIM: 300535,300555,309000) PREDICTED: i  (831 aa)
 initn: 5289 init1: 5210 opt: 5292  Z-score: 4979.0  bits: 932.4 E(85289):    0
Smith-Waterman score: 5292; 97.3% identity (98.4% similar) in 804 aa overlap (1-804:1-803)

               10        20        30        40        50        60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
       ::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
       :     .  .. .  .. .: :..                                    
XP_016 IRILCDQSLRSWMRTFDLFPYPALTKRKQGVDNNDLKAWDIEATALVLFSFR        
     780       790       800       810       820       830         

>>XP_005262479 (OMIM: 300535,300555,309000) PREDICTED: i  (744 aa)
 initn: 5055 init1: 5055 opt: 5055  Z-score: 4756.9  bits: 891.1 E(85289):    0
Smith-Waterman score: 5055; 100.0% identity (100.0% similar) in 744 aa overlap (159-902:1-744)

      130       140       150       160       170       180        
pF1KB3 DSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKM
                                     ::::::::::::::::::::::::::::::
XP_005                               MNLDKKINSQNQPTGIHREPPPPPFSVNKM
                                             10        20        30

      190       200       210       220       230       240        
pF1KB3 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTW
               40        50        60        70        80        90

      250       260       270       280       290       300        
pF1KB3 NVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHS
              100       110       120       130       140       150

      310       320       330       340       350       360        
pF1KB3 KAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNT
              160       170       180       190       200       210

      370       380       390       400       410       420        
pF1KB3 TFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRL
              220       230       240       250       260       270

      430       440       450       460       470       480        
pF1KB3 CMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWD
              280       290       300       310       320       330

      490       500       510       520       530       540        
pF1KB3 SSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVF
              340       350       360       370       380       390

      550       560       570       580       590       600        
pF1KB3 EDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLND
              400       410       420       430       440       450

      610       620       630       640       650       660        
pF1KB3 SQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDY
              460       470       480       490       500       510

      670       680       690       700       710       720        
pF1KB3 FLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGA
              520       530       540       550       560       570

      730       740       750       760       770       780        
pF1KB3 SERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSV
              580       590       600       610       620       630

      790       800       810       820       830       840        
pF1KB3 AEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELL
              640       650       660       670       680       690

      850       860       870       880       890       900  
pF1KB3 KFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED
              700       710       720       730       740    

>>NP_001284363 (OMIM: 147264) type II inositol 1,4,5-tri  (749 aa)
 initn: 2591 init1: 1570 opt: 2078  Z-score: 1958.1  bits: 373.3 E(85289): 2.5e-102
Smith-Waterman score: 2657; 51.1% identity (78.2% similar) in 751 aa overlap (147-896:16-745)

        120       130       140       150       160       170      
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
                                     :.. :.. : ... .:..  .:..: ... 
NP_001                MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
                              10        20        30        40     

        180       190       200       210       220       230      
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
       .       .. :. : .  . ... ..  .:.:.       : :. ..:  : ..:..:.
NP_001 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
          50         60        70                80        90      

        240       250       260       270       280       290      
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
        ::.::::.::.:::::::   :. ::.   . ::.::.:::::::: ::::. .. ::.
NP_001 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
        100       110       120       130       140       150      

        300       310       320       330       340       350      
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
       ::  :: .:::  ::: ::.:.::::.:::.......  :: .. .:::::::::.::::
NP_001 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
        160       170       180       190       200       210      

        360       370       380       390       400       410      
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
       ::::.:: ::::..:.::::::::.:..:::::::::::.::.:  :. .:: :.: .:.
NP_001 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
        220       230       240       250       260       270      

        420       430       440       450       460       470      
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
       :..::::::::.   :...::.::..::.: :  .:::.:: . : .:  :.:::. : :
NP_001 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
        280       290       300       310       320       330      

        480       490       500       510       520       530      
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
       :::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
NP_001 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
        340       350       360       370       380       390      

        540       550       560       570       580       590      
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
       .::... :::..:. :: .:.:::  .::. ::.::: :.:::. ::. :.: : .::::
NP_001 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
        400       410       420       430       440       450      

        600       610       620       630       640       650      
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
       :::: :: : .. .::: :: :.: .:.: :.  :.:.:...:.: ..: ::::::::::
NP_001 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
         460       470       480       490       500       510     

        660       670       680       690       700       710      
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
       ::::::::::::::..::::::::::. ...:: :..:: ..:.  . .:          
NP_001 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
         520       530       540       550       560               

        720        730       740       750       760       770     
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
       .:. .   :.:.. . :...:::.:..::.:.. : .:::::: ::.. :...: :::::
NP_001 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDT
         570       580       590       600       610       620     

         780       790       800       810       820       830     
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
       .. ... .::::::::::.:::.::::::::  :. ::. . .    .:::: ::  :.:
NP_001 GMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKN
         630       640       650       660       670       680     

         840       850       860       870       880       890     
pF1KB3 VFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGF
       ::.::::::::::: :  : .. :..:..: ::::: : .   .   .....: .:.  :
NP_001 VFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQF
         690       700       710       720        730       740    

         900  
pF1KB3 LLGSEED
       :      
NP_001 LCNPL  
              

>>XP_016856696 (OMIM: 147264) PREDICTED: type II inosito  (794 aa)
 initn: 2591 init1: 1570 opt: 2078  Z-score: 1957.7  bits: 373.3 E(85289): 2.6e-102
Smith-Waterman score: 2657; 51.1% identity (78.2% similar) in 751 aa overlap (147-896:61-790)

        120       130       140       150       160       170      
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
                                     :.. :.. : ... .:..  .:..: ... 
XP_016 AELELEMPTPRGCNSALVTWPGYATIGGGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
               40        50        60        70        80        90

        180       190       200       210       220       230      
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
       .       .. :. : .  . ... ..  .:.:.       : :. ..:  : ..:..:.
XP_016 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
              100        110        120              130       140 

        240       250       260       270       280       290      
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
        ::.::::.::.:::::::   :. ::.   . ::.::.:::::::: ::::. .. ::.
XP_016 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
             150       160       170       180       190       200 

        300       310       320       330       340       350      
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
       ::  :: .:::  ::: ::.:.::::.:::.......  :: .. .:::::::::.::::
XP_016 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
             210       220       230       240       250       260 

        360       370       380       390       400       410      
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
       ::::.:: ::::..:.::::::::.:..:::::::::::.::.:  :. .:: :.: .:.
XP_016 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
             270       280       290       300       310       320 

        420       430       440       450       460       470      
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
       :..::::::::.   :...::.::..::.: :  .:::.:: . : .:  :.:::. : :
XP_016 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
             330       340       350       360       370       380 

        480       490       500       510       520       530      
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
       :::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
XP_016 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
             390       400       410       420       430       440 

        540       550       560       570       580       590      
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
       .::... :::..:. :: .:.:::  .::. ::.::: :.:::. ::. :.: : .::::
XP_016 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
             450       460       470       480       490        500

        600       610       620       630       640       650      
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
       :::: :: : .. .::: :: :.: .:.: :.  :.:.:...:.: ..: ::::::::::
XP_016 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
              510       520       530       540       550       560

        660       670       680       690       700       710      
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
       ::::::::::::::..::::::::::. ...:: :..:: ..:.  . .:          
XP_016 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
              570       580       590       600       610          

        720        730       740       750       760       770     
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
       .:. .   :.:.. . :...:::.:..::.:.. : .:::::: ::.. :...: :::::
XP_016 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDT
              620       630       640       650       660       670

         780       790       800       810       820       830     
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
       .. ... .::::::::::.:::.::::::::  :. ::. . .    .:::: ::  :.:
XP_016 GMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKN
              680       690       700       710       720       730

         840       850       860       870       880       890     
pF1KB3 VFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGF
       ::.::::::::::: :  : .. :..:..: ::::: : .   .   .....: .:.  :
XP_016 VFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQF
              740       750       760       770        780         

         900  
pF1KB3 LLGSEED
       :      
XP_016 LCNPL  
     790      

>>XP_016856695 (OMIM: 147264) PREDICTED: type II inosito  (823 aa)
 initn: 2129 init1: 1547 opt: 2078  Z-score: 1957.5  bits: 373.3 E(85289): 2.7e-102
Smith-Waterman score: 2174; 51.0% identity (78.6% similar) in 608 aa overlap (147-753:180-767)

        120       130       140       150       160       170      
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
                                     :.. :.. : ... .:..  .:..: ... 
XP_016 AELELEMPTPRGCNSALVTWPGYATIGGGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
     150       160       170       180       190       200         

        180       190       200       210       220       230      
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
       .       .. :. : .  . ... ..  .:.:.       : :. ..:  : ..:..:.
XP_016 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
     210       220        230        240              250       260

        240       250       260       270       280       290      
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
        ::.::::.::.:::::::   :. ::.   . ::.::.:::::::: ::::. .. ::.
XP_016 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
              270       280       290       300       310       320

        300       310       320       330       340       350      
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
       ::  :: .:::  ::: ::.:.::::.:::.......  :: .. .:::::::::.::::
XP_016 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
              330       340       350       360       370       380

        360       370       380       390       400       410      
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
       ::::.:: ::::..:.::::::::.:..:::::::::::.::.:  :. .:: :.: .:.
XP_016 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
              390       400       410       420       430       440

        420       430       440       450       460       470      
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
       :..::::::::.   :...::.::..::.: :  .:::.:: . : .:  :.:::. : :
XP_016 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
              450       460       470       480       490       500

        480       490       500       510       520       530      
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
       :::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
XP_016 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
              510       520       530       540       550       560

        540       550       560       570       580       590      
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
       .::... :::..:. :: .:.:::  .::. ::.::: :.:::. ::. :.: : .::::
XP_016 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
              570       580       590       600       610          

        600       610       620       630       640       650      
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
       :::: :: : .. .::: :: :.: .:.: :.  :.:.:...:.: ..: ::::::::::
XP_016 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
     620       630       640       650       660       670         

        660       670       680       690       700       710      
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
       ::::::::::::::..::::::::::. ...:: :..:: ..:.  . .:          
XP_016 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
     680       690       700       710       720                   

        720        730       740       750       760       770     
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
       .:. .   :.:.. . :...:::.:..::.:.. : .:                      
XP_016 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQFYNRCLKTYCRNMPGKACKMNS
     730       740       750       760       770       780         

         780       790       800       810       820       830     
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
                                                                   
XP_016 PHQPKSDHLSGDSEASPHCSFLHSAIDIARSGNH                          
     790       800       810       820                             




902 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:04:59 2016 done: Thu Nov  3 21:05:01 2016
 Total Scan time: 13.490 Total Display time:  0.280

Function used was FASTA [36.3.4 Apr, 2011]
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