Result of FASTA (omim) for pF1KB9409
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9409, 289 aa
  1>>>pF1KB9409 289 - 289 aa - 289 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1677+/-0.000352; mu= 15.8923+/- 0.022
 mean_var=64.1065+/-13.165, 0's: 0 Z-trim(113.7): 56  B-trim: 1871 in 2/50
 Lambda= 0.160186
 statistics sampled from 23167 (23229) to 23167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.272), width:  16
 Scan time:  7.460

The best scores are:                                      opt bits E(85289)
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 1928 454.2 1.4e-127
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 1190 283.6   3e-76
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 1174 279.9 3.9e-75
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242)  923 221.9 9.6e-58
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276)  862 207.8 1.9e-53
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211)  819 197.8 1.5e-50
NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D ( 220)  548 135.2 1.1e-31
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195)  507 125.7   7e-29
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421)  303 78.7 2.1e-14
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421)  303 78.7 2.1e-14
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421)  303 78.7 2.1e-14
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421)  303 78.7 2.1e-14
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421)  303 78.7 2.1e-14
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464)  303 78.8 2.2e-14
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465)  303 78.8 2.2e-14
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288)  294 76.6 6.4e-14
NP_001274363 (OMIM: 123834) G1/S-specific cyclin-D (  96)  288 74.9 6.7e-14
NP_001129598 (OMIM: 123834) G1/S-specific cyclin-D (  96)  288 74.9 6.7e-14
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404)  295 76.9 7.2e-14
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404)  295 76.9 7.2e-14
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404)  295 76.9 7.2e-14
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404)  295 76.9 7.2e-14
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens]  ( 432)  293 76.4   1e-13
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395)  271 71.3 3.3e-12
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407)  271 71.3 3.4e-12
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410)  271 71.3 3.4e-12
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433)  244 65.1 2.7e-10
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365)  231 62.1 1.9e-09
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398)  231 62.1   2e-09
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo  ( 786)  212 57.9 7.4e-08
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867)  212 57.9   8e-08
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350)  202 55.3 1.9e-07
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478)  196 54.0 6.4e-07
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens]  ( 295)  190 52.5 1.1e-06
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens]  ( 295)  190 52.5 1.1e-06
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens]  ( 344)  163 46.3 9.6e-05
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344)  163 46.3 9.6e-05
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344)  163 46.3 9.6e-05
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395)  169 48.1 0.00012
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395)  169 48.1 0.00012
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396)  169 48.1 0.00012
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403)  169 48.1 0.00012
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404)  169 48.1 0.00012
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404)  169 48.1 0.00012
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404)  169 48.1 0.00012
NP_001186118 (OMIM: 601953) cyclin-H isoform 2 [Ho ( 270)  133 39.3  0.0096
XP_016865503 (OMIM: 601953) PREDICTED: cyclin-H is ( 272)  133 39.3  0.0096
XP_005248686 (OMIM: 601953) PREDICTED: cyclin-H is ( 276)  133 39.3  0.0097


>>NP_001750 (OMIM: 123833,615938) G1/S-specific cyclin-D  (289 aa)
 initn: 1928 init1: 1928 opt: 1928  Z-score: 2411.7  bits: 454.2 E(85289): 1.4e-127
Smith-Waterman score: 1928; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)

               10        20        30        40        50        60
pF1KB9 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV
              190       200       210       220       230       240

              250       260       270       280         
pF1KB9 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL
              250       260       270       280         

>>NP_444284 (OMIM: 168461,193300,254500) G1/S-specific c  (295 aa)
 initn: 1176 init1: 1059 opt: 1190  Z-score: 1489.9  bits: 283.6 E(85289): 3e-76
Smith-Waterman score: 1190; 61.8% identity (81.9% similar) in 293 aa overlap (2-289:4-295)

                 10        20        30        40        50        
pF1KB9   MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRM
          .::: ::. .:::  : ::: .::::. .:  ::   :. ::::::::.. : ::..
NP_444 MEHQLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKI
               10        20         30        40        50         

       60        70        80        90       100       110        
pF1KB9 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPL
       ::::::::::::::::::::::::::::::.  :. ::.::::::.:::.:::.::: ::
NP_444 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPL
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB9 TAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIR
       :::::::::::::.:.:::. ::....::::::::.::::::::.: :.:. .:. ..::
NP_444 TAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIR
     120       130       140       150       160       170         

      180       190       200       210       220       230        
pF1KB9 KHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNT
       ::::::.:::::: ::   ::::.:.::: ::. ::.     . :.   ::..:... . 
NP_444 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC
     180       190       200       210       220       230         

      240       250       260            270       280         
pF1KB9 DVDCLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL
       : :::.::::::::.: .::.: .:..     ..  . :.:.: : :::::::.:.
NP_444 DPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI
     240       250       260       270       280       290     

>>NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 isofo  (292 aa)
 initn: 1171 init1: 977 opt: 1174  Z-score: 1469.9  bits: 279.9 E(85289): 3.9e-75
Smith-Waterman score: 1174; 61.6% identity (81.8% similar) in 297 aa overlap (1-289:1-292)

                10        20        30        40        50         
pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV
       ::::: : .  . ::  :  :: :.::::.:: .::::.:. :::.:::..:.:.::.:.
NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT
       : :::::::::.:::::::::::::::.:. ::: :..:::::::::.:::::.::.:::
NP_001 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK
        ::::::::....:..: .::..:::::::.::::  :::.  ::..:   :.. .:..:
NP_001 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD
       :::::.::::::. :::::::::::::.:::. ::     . :.. : :::::: ::.:.
NP_001 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTE
              190       200       210           220       230      

     240       250       260              270       280         
pF1KB9 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL
       ::::.::::::::.: .::..  : . .       ::.:.   .:.::::::  : :
NP_001 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL
        240       250       260       270        280       290  

>>NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D3 is  (242 aa)
 initn: 915 init1: 746 opt: 923  Z-score: 1157.7  bits: 221.9 E(85289): 9.6e-58
Smith-Waterman score: 923; 62.3% identity (82.3% similar) in 231 aa overlap (66-289:17-242)

          40        50        60        70        80        90     
pF1KB9 RYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPK
                                     :::::.:::::::::::::::.:. ::: :
NP_001               MKSAGGSGRSLLPSPRVCEEQRCEEEVFPLAMNYLDRYLSCVPTRK
                             10        20        30        40      

         100       110       120       130       140       150     
pF1KB9 SHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVT
       ..:::::::::.:::::.::.::: ::::::::....:..: .::..:::::::.:::: 
NP_001 AQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVI
         50        60        70        80        90       100      

         160       170       180       190       200       210     
pF1KB9 PHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQ
        :::.  ::..:   :.. .:..::::::.::::::. :::::::::::::.:::. :: 
NP_001 AHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG
        110       120       130       140       150       160      

         220       230       240       250       260               
pF1KB9 QDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRD-------G
           . :.. : :::::: ::.:.::::.::::::::.: .::..  : . .       :
NP_001 ----ACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRG
            170       180       190       200       210       220  

      270       280         
pF1KB9 SKSEDELDQASTPTDVRDIDL
       :.:.   .:.::::::  : :
NP_001 SSSQGP-SQTSTPTDVTAIHL
             230       240  

>>XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specific c  (276 aa)
 initn: 867 init1: 842 opt: 862  Z-score: 1080.6  bits: 207.8 E(85289): 1.9e-53
Smith-Waterman score: 862; 65.4% identity (86.9% similar) in 191 aa overlap (1-190:1-191)

                10        20        30        40        50         
pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV
       ::::: : .  . ::  :  :: :.::::.:: .::::.:. :::.:::..:.:.::.:.
XP_011 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT
       : :::::::::.:::::::::::::::.:. ::: :..:::::::::.:::::.::.:::
XP_011 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK
        ::::::::....:..: .::..:::::::.::::  :::.  ::..:   :.. .:..:
XP_011 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD
       :::::.:::::                                                 
XP_011 HAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPRAQPDQHSYR
              190       200       210       220       230       240

>>NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D3 is  (211 aa)
 initn: 811 init1: 642 opt: 819  Z-score: 1028.6  bits: 197.8 E(85289): 1.5e-50
Smith-Waterman score: 819; 60.2% identity (81.0% similar) in 216 aa overlap (81-289:1-211)

               60        70        80        90       100       110
pF1KB9 IQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLAS
                                     ::::::.:. ::: :..:::::::::.:::
NP_001                               MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS
                                             10        20        30

              120       130       140       150       160       170
pF1KB9 KLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQ
       ::.::.::: ::::::::....:..: .::..:::::::.::::  :::.  ::..:   
NP_001 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP
               40        50        60        70        80        90

              180       190       200       210       220       230
pF1KB9 REKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTE
       :.. .:..::::::.::::::. :::::::::::::.:::. ::     . :.. : :::
NP_001 RDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTE
              100       110       120       130           140      

              240       250       260              270       280   
pF1KB9 LLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTD
       ::: ::.:.::::.::::::::.: .::..  : . .       ::.:.   .:.:::::
NP_001 LLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTD
        150       160       170       180       190        200     

             
pF1KB9 VRDIDL
       :  : :
NP_001 VTAIHL
         210 

>>NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D3 is  (220 aa)
 initn: 565 init1: 371 opt: 548  Z-score: 689.9  bits: 135.2 E(85289): 1.1e-31
Smith-Waterman score: 643; 43.4% identity (58.9% similar) in 297 aa overlap (1-289:1-220)

                10        20        30        40        50         
pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV
       ::::: : .  . ::  :  :: :.::::.:: .::::.:. :::.:::..:.:.::.:.
NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT
       : ::::                                                      
NP_001 AYWMLE------------------------------------------------------
                                                                   

     120       130       140       150       160       170         
pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK
                         .::..:::::::.::::  :::.  ::..:   :.. .:..:
NP_001 ------------------DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK
                           70        80        90       100        

     180       190       200       210       220       230         
pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD
       :::::.::::::. :::::::::::::.:::. ::     . :.. : :::::: ::.:.
NP_001 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTE
      110       120       130       140           150       160    

     240       250       260              270       280         
pF1KB9 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL
       ::::.::::::::.: .::..  : . .       ::.:.   .:.::::::  : :
NP_001 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL
          170       180       190       200        210       220

>>XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specific c  (195 aa)
 initn: 507 init1: 507 opt: 507  Z-score: 639.5  bits: 125.7 E(85289): 7e-29
Smith-Waterman score: 507; 65.5% identity (89.1% similar) in 110 aa overlap (81-190:1-110)

               60        70        80        90       100       110
pF1KB9 IQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLAS
                                     ::::::.:. ::: :..:::::::::.:::
XP_011                               MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS
                                             10        20        30

              120       130       140       150       160       170
pF1KB9 KLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQ
       ::.::.::: ::::::::....:..: .::..:::::::.::::  :::.  ::..:   
XP_011 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP
               40        50        60        70        80        90

              180       190       200       210       220       230
pF1KB9 REKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTE
       :.. .:..::::::.:::::                                        
XP_011 RDRQALVKKHAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPR
              100       110       120       130       140       150

>>XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 isofo  (421 aa)
 initn: 251 init1: 251 opt: 303  Z-score: 379.7  bits: 78.7 E(85289): 2.1e-14
Smith-Waterman score: 309; 29.1% identity (59.4% similar) in 254 aa overlap (24-275:169-407)

                      10        20        30        40        50   
pF1KB9        MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQP
                                     ... : :   : :. :.  :.:  : ::  
XP_011 SPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKK-QPDITE
      140       150       160       170       180       190        

            60        70        80        90       100       110   
pF1KB9 YMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLK
        :: ... :..:: :: : . :.. ::.:.:::::. . . ...:::.:.. :.:::: .
XP_011 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE
       200       210       220       230       240       250       

           120       130       140       150       160       170   
pF1KB9 ETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREK
       :  :  ....   ::..   ..::. : ..:  : ..:.. : ..:. . ::.     . 
XP_011 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT
       260       270       280       290       300       310       

           180       190       200       210       220         230 
pF1KB9 LSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDA--LTEL
        .: .  :.  ..:  .:  :  : ::.::.    ::.:       ... : .     : 
XP_011 ENLAKYVAE--LSLLEAD-PFLKYLPSLIAA----AAFC-------LANYTVNKHFWPET
       320         330        340                  350       360   

             240       250       260       270       280         
pF1KB9 LAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL
       :: .:. ... .  :  ... . :.  .. .:  :.  :.   :              
XP_011 LAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
           370       380       390       400       410       420 

>>XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 isofo  (421 aa)
 initn: 251 init1: 251 opt: 303  Z-score: 379.7  bits: 78.7 E(85289): 2.1e-14
Smith-Waterman score: 309; 29.1% identity (59.4% similar) in 254 aa overlap (24-275:169-407)

                      10        20        30        40        50   
pF1KB9        MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQP
                                     ... : :   : :. :.  :.:  : ::  
XP_011 SPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKK-QPDITE
      140       150       160       170       180       190        

            60        70        80        90       100       110   
pF1KB9 YMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLK
        :: ... :..:: :: : . :.. ::.:.:::::. . . ...:::.:.. :.:::: .
XP_011 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE
       200       210       220       230       240       250       

           120       130       140       150       160       170   
pF1KB9 ETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREK
       :  :  ....   ::..   ..::. : ..:  : ..:.. : ..:. . ::.     . 
XP_011 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT
       260       270       280       290       300       310       

           180       190       200       210       220         230 
pF1KB9 LSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDA--LTEL
        .: .  :.  ..:  .:  :  : ::.::.    ::.:       ... : .     : 
XP_011 ENLAKYVAE--LSLLEAD-PFLKYLPSLIAA----AAFC-------LANYTVNKHFWPET
       320         330        340                  350       360   

             240       250       260       270       280         
pF1KB9 LAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL
       :: .:. ... .  :  ... . :.  .. .:  :.  :.   :              
XP_011 LAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
           370       380       390       400       410       420 




289 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:25:11 2016 done: Thu Nov  3 18:25:12 2016
 Total Scan time:  7.460 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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