Result of FASTA (omim) for pF1KB5639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5639, 440 aa
  1>>>pF1KB5639 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9079+/-0.000303; mu= 16.5284+/- 0.019
 mean_var=116.9296+/-23.472, 0's: 0 Z-trim(120.5): 76  B-trim: 1173 in 2/56
 Lambda= 0.118607
 statistics sampled from 35764 (35864) to 35764 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.42), width:  16
 Scan time: 10.290

The best scores are:                                      opt bits E(85289)
NP_003833 (OMIM: 275355,603612) tumor necrosis fac ( 440) 2988 522.0 1.2e-147
XP_016869433 (OMIM: 275355,603612) PREDICTED: tumo ( 375) 2450 429.8 5.7e-120
NP_671716 (OMIM: 275355,603612) tumor necrosis fac ( 411) 1504 268.0 3.3e-71
NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 1088 196.8 8.4e-50
NP_003835 (OMIM: 603611) tumor necrosis factor rec ( 468)  706 131.5 4.6e-30
NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259)  599 112.9 9.8e-25
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399)  253 53.9 8.8e-07
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314)  249 53.1 1.2e-06
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368)  249 53.2 1.3e-06
NP_001307548 (OMIM: 134637,601859) tumor necrosis  ( 197)  243 51.9 1.8e-06
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220)  243 51.9 1.9e-06
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335)  243 52.1 2.6e-06
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350)  243 52.1 2.6e-06
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362)  243 52.2 2.7e-06
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362)  243 52.2 2.7e-06
XP_011538066 (OMIM: 134637,601859) PREDICTED: tumo ( 389)  243 52.2 2.8e-06
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255)  235 50.6 5.5e-06
NP_001257916 (OMIM: 600979) tumor necrosis factor  ( 416)  235 50.9 7.7e-06
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435)  235 50.9 7.9e-06
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440)  202 45.2  0.0004
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440)  202 45.2  0.0004
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461)  202 45.2 0.00041
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462)  202 45.2 0.00041
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484)  202 45.3 0.00043
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491)  202 45.3 0.00043
NP_001056 (OMIM: 142680,191190,614810) tumor necro ( 455)  201 45.1 0.00046
NP_001284534 (OMIM: 602746) tumor necrosis factor  ( 184)  191 43.0  0.0008
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197)  191 43.0 0.00084
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283)  191 43.2  0.0011
NP_003781 (OMIM: 603366) tumor necrosis factor rec ( 417)  184 42.1  0.0033
NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277)  177 40.8  0.0056
XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277)  177 40.8  0.0056
XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303)  177 40.8   0.006
XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303)  177 40.8   0.006
NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426)  179 41.3   0.006
XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594)  177 41.1  0.0096
NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595)  177 41.1  0.0096


>>NP_003833 (OMIM: 275355,603612) tumor necrosis factor   (440 aa)
 initn: 2988 init1: 2988 opt: 2988  Z-score: 2771.5  bits: 522.0 E(85289): 1.2e-147
Smith-Waterman score: 2988; 99.5% identity (99.8% similar) in 440 aa overlap (1-440:1-440)

               10        20        30        40        50        60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
       ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_003 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
              370       380       390       400       410       420

              430       440
pF1KB5 HLLSSGKFMYLEGNADSAMS
       ::::::::::::::::::::
NP_003 HLLSSGKFMYLEGNADSAMS
              430       440

>>XP_016869433 (OMIM: 275355,603612) PREDICTED: tumor ne  (375 aa)
 initn: 2450 init1: 2450 opt: 2450  Z-score: 2274.8  bits: 429.8 E(85289): 5.7e-120
Smith-Waterman score: 2450; 99.7% identity (100.0% similar) in 357 aa overlap (84-440:19-375)

            60        70        80        90       100       110   
pF1KB5 ALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFC
                                     ::::::::::::::::::::::::::::::
XP_016             MDDVWGMRTIEAPNSTAQGHHISEDGRDCISCKYGQDYSTHWNDLLFC
                           10        20        30        40        

           120       130       140       150       160       170   
pF1KB5 LRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPW
       50        60        70        80        90       100        

           180       190       200       210       220       230   
pF1KB5 SDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCK
       :::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCK
      110       120       130       140       150       160        

           240       250       260       270       280       290   
pF1KB5 SLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQE
      170       180       190       200       210       220        

           300       310       320       330       340       350   
pF1KB5 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
      230       240       250       260       270       280        

           360       370       380       390       400       410   
pF1KB5 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
      290       300       310       320       330       340        

           420       430       440
pF1KB5 AKQKIEDHLLSSGKFMYLEGNADSAMS
       :::::::::::::::::::::::::::
XP_016 AKQKIEDHLLSSGKFMYLEGNADSAMS
      350       360       370     

>>NP_671716 (OMIM: 275355,603612) tumor necrosis factor   (411 aa)
 initn: 1503 init1: 1503 opt: 1504  Z-score: 1399.5  bits: 268.0 E(85289): 3.3e-71
Smith-Waterman score: 2734; 93.2% identity (93.2% similar) in 440 aa overlap (1-440:1-411)

               10        20        30        40        50        60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
       ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_671 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
       ::::                             :::::::::::::::::::::::::::
NP_671 KESG-----------------------------IIIGVTVAAVVLIVAVFVCKSLLWKKV
                                           190       200       210 

              250       260       270       280       290       300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
             220       230       240       250       260       270 

              310       320       330       340       350       360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
             280       290       300       310       320       330 

              370       380       390       400       410       420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
             340       350       360       370       380       390 

              430       440
pF1KB5 HLLSSGKFMYLEGNADSAMS
       ::::::::::::::::::::
NP_671 HLLSSGKFMYLEGNADSAMS
             400       410 

>>NP_003831 (OMIM: 603614) tumor necrosis factor recepto  (386 aa)
 initn: 1029 init1: 584 opt: 1088  Z-score: 1015.1  bits: 196.8 E(85289): 8.4e-50
Smith-Waterman score: 1088; 53.2% identity (71.2% similar) in 344 aa overlap (5-336:5-342)

               10        20        30          40        50        
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQ
           ::..:.::.::  . :: : : :.:: :  :: :  :. ..:::: : ..:: : .
NP_003 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB5 QDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTR
       :: .::: .::::.: : .:  :: : : ::    :  :  : ::.   :.:  :: :: 
NP_003 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB5 CDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIEC
       : ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.:
NP_003 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB5 VHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWK
        ..::... .:..::.:::::.  :  :::     ::: : :  ....:. : :.    :
NP_003 -KNESAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----K
               190       200       210        220       230        

      240       250       260               270         280        
pF1KB5 KVLPYLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQE
       : . ::::::::::: :::: :         :. ::::::. :: .:   :::::: :::
NP_003 KFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQE
          240       250       260       270       280       290    

      290       300       310       320       330       340        
pF1KB5 MEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADL
       .. :: :: :::..  : : ..::: ::::  ::::::::.:..: ..            
NP_003 IQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLE
          300       310       320       330       340       350    

      350       360       370       380       390       400        
pF1KB5 VPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALET
                                                                   
NP_003 EGHAKETIQDQLVGSEKLFYEEDEAGSATSCL                            
          360       370       380                                  

>>NP_003835 (OMIM: 603611) tumor necrosis factor recepto  (468 aa)
 initn: 1387 init1: 645 opt: 706  Z-score: 660.8  bits: 131.5 E(85289): 4.6e-30
Smith-Waterman score: 1343; 52.6% identity (68.0% similar) in 447 aa overlap (5-440:60-466)

                                         10        20        30    
pF1KB5                           MEQRGQNAPAASGARKRHGPGPREARGARPGLRV
                                     ::..:.:  ::  ..:::: :: : : :::
NP_003 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
      30        40        50        60         70        80        

           40         50        60        70        80        90   
pF1KB5 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
        ::. .::..::: .: . .: :  .:    :  . :: . ::   ::::: : ::    
NP_003 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
       90       100       110           120       130       140    

           100       110       120       130       140       150   
pF1KB5 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
       :  :  :  :..  :.:. :: :: : : : : :::::::::.:::. ::::...: :::
NP_003 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
          150       160       170       180       190       200    

           160       170       180       190       200       210   
pF1KB5 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSG
       :::  ::::::::: ::::::::::::::::. :.                         
NP_003 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHN-----------------------IW
          210       220       230                              240 

           220       230        240       250       260            
pF1KB5 IIIGVTVAAVVLIVAVF-VCKSLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRP
       .:. ::... .:.:::. ::              : :: ::::. .::         . :
NP_003 VILVVTLVVPLLLVAVLIVCCC------------IGSGCGGDPKCMDRVCFWRLGLLRGP
             250       260                   270       280         

         270       280         290       300       310       320   
pF1KB5 GAEDNVLNEIVSILQP--TQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRR
       :::::. :::.:  .   : : ::.:: ::::. :::.. ::::.. :: ::::: ::::
NP_003 GAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRR
     290       300       310       320       330       340         

           330       340       350       360       370       380   
pF1KB5 RLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLY
       ::::::: .::::::   :: ::..::::::. :::.: :  ::: :..: .::  :.::
NP_003 RLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALY
     350       360       370       380       390       400         

           390       400       410       420       430       440  
pF1KB5 TMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS  
       .::.::::::::.::.:::::::: . :: :..::.: :..::::.::: .. ::.:  
NP_003 AMLMKWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
     410       420       430       440       450       460        

>>NP_003832 (OMIM: 603613) tumor necrosis factor recepto  (259 aa)
 initn: 695 init1: 403 opt: 599  Z-score: 565.1  bits: 112.9 E(85289): 9.8e-25
Smith-Waterman score: 599; 52.3% identity (72.7% similar) in 176 aa overlap (33-206:3-176)

             10        20        30          40        50        60
pF1KB5 QRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQQD
                                     :.::::  :.:..:::: : : ::  ..:.
NP_003                             MARIPKTLKFVVVIVAVLLPVLAYSATTARQE
                                           10        20        30  

               70        80        90       100       110       120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
        .::: .::::.: : .   :: : : ::    :  :  : ::..  :.   :. :: : 
NP_003 EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCK
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
       : . . : :: ::.:::::.:::::.:.:::::::: . :: : :.:..:: :.::.:: 
NP_003 SDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC-SRCPSGEVQVSNCTSWDDIQCV-
            100       110       120        130       140       150 

              190       200       210       220       230       240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
       .: :.. . :.::.:::...::::::                                  
NP_003 EEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAE
              160       170       180       190       200       210

>>XP_005253745 (OMIM: 600979) PREDICTED: tumor necrosis   (399 aa)
 initn: 137 init1:  79 opt: 253  Z-score: 242.7  bits: 53.9 E(85289): 8.8e-07
Smith-Waterman score: 253; 29.2% identity (50.6% similar) in 257 aa overlap (81-316:62-301)

               60        70        80        90            100     
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDG---RD--CISCKYGQDYST
                                     :::: ..:      ::  : .:  .. :. 
XP_005 AVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENS-YNE
              40        50        60        70        80         90

         110       120         130       140       150       160   
pF1KB5 HWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRG
       ::: : .:  :  ::   :  :..:::. :.: :.:. : :    . : : .:.      
XP_005 HWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE-CTHCEL-----
              100       110       120       130        140         

           170       180       190         200          210        
pF1KB5 MVKVGDCTPWSDIECVHKESGTKHSGEAP--AVEETVTSSPGT---PASPCSLSGIIIGV
          ..:: : .. : .. : :  ..  .:  : .   ::::..   : . :  .:..   
XP_005 ---LSDCPPGTEAE-LKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLV---
             150        160       170       180       190          

      220       230       240          250       260       270     
pF1KB5 TVAAVVLIVAVFVCKSLLWKKVLPYLKGIC---SGGGGDPERVDRSSQRPGAEDNVLNEI
         ::     .  .::. : . . : ..:        :  :. :  : . : :.   . ..
XP_005 -EAAPGTAQSDTTCKNPL-EPLPPEMSGSLLKRRPQGEGPNPVAGSWEPPKAHP-YFPDL
        200       210        220       230       240        250    

         280       290          300          310       320         
pF1KB5 VSILQPTQVPEQEMEVQEPAEPT---GV-NMLSPGE--SEHLLEPAEAERSQRRRLLVPA
       :. : : .   . . .  :: :.   :: .. :: .   :  :::.:             
XP_005 VQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHV
          260       270       280       290       300       310    

     330       340       350       360       370       380         
pF1KB5 NEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKW
                                                                   
XP_005 TGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAW
          320       330       340       350       360       370    

>>NP_690610 (OMIM: 134637,601859) tumor necrosis factor   (314 aa)
 initn: 154 init1:  95 opt: 249  Z-score: 240.3  bits: 53.1 E(85289): 1.2e-06
Smith-Waterman score: 254; 32.6% identity (54.9% similar) in 175 aa overlap (81-234:63-231)

               60        70        80              90       100    
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHH------ISEDGRDCISCKYGQDYS
                                     ::::..      .. :  ::. :. :..:.
NP_690 KGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYT
             40        50        60        70        80        90  

          110       120          130       140       150       160 
pF1KB5 THWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCP
        . .    : ::  :: :   :::.. :: :.:: :.:. . : .    : :  : : : 
NP_690 DKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNSTVCEHCDPC-TKCE
            100       110        120       130       140        150

             170       180              190       200          210 
pF1KB5 RGMVKVGDCTPWSDIECVH-------KESGTKHSGEAPAVEETVTSSPGTPA---SPCSL
       .:..:  .::  :. .: .       ...  ::  :  . .:. : .: : :   :  .:
NP_690 HGIIK--ECTLTSNTKCKEEVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDL
                160       170       180       190       200        

             220         230       240       250       260         
pF1KB5 SGIIIGVTVAAVVLIVAV--FVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAED
       :  :  .:.:.:. .  :  :: :.                                   
NP_690 SKYI--TTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGK
      210         220       230       240       250       260      

>>XP_011538067 (OMIM: 134637,601859) PREDICTED: tumor ne  (368 aa)
 initn: 154 init1:  95 opt: 249  Z-score: 239.5  bits: 53.2 E(85289): 1.3e-06
Smith-Waterman score: 265; 28.5% identity (53.0% similar) in 249 aa overlap (18-234:43-285)

                            10        20        30        40       
pF1KB5              MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLL
                                     :: .     :.. .: .:  ::...... :
XP_011 HVSFPERGINITWELMLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARL
             20        30        40        50        60        70  

        50        60         70        80                        90
pF1KB5 LVSAESALITQQDLAPQQ-RAAPQQKRSSPSEGL----------CPPGHH------ISED
         .. .: .:. .    . : .    ...  :::          ::::..      .. :
XP_011 SSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGD
             80        90       100       110       120       130  

              100       110       120          130       140       
pF1KB5 GRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREE
         ::. :. :..:. . .    : ::  :: :   :::.. :: :.:: :.:. . : . 
XP_011 EPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNS
            140       150       160       170        180       190 

       150       160       170       180              190       200
pF1KB5 DSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH-------KESGTKHSGEAPAVEETVTS
          : :  : : : .:..:  .::  :. .: .       ...  ::  :  . .:. : 
XP_011 TVCEHCDPC-TKCEHGIIK--ECTLTSNTKCKEEVKRKEVQKTCRKHRKENQGSHESPTL
             200          210       220       230       240        

                 210       220         230       240       250     
pF1KB5 SPGTPA---SPCSLSGIIIGVTVAAVVLIVAV--FVCKSLLWKKVLPYLKGICSGGGGDP
       .: : :   :  .::  :  .:.:.:. .  :  :: :.                     
XP_011 NPETVAINLSDVDLSKYI--TTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
      250       260         270       280       290       300      

         260       270       280       290       300       310     
pF1KB5 ERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPA
                                                                   
XP_011 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
        310       320       330       340       350       360      

>>NP_001307548 (OMIM: 134637,601859) tumor necrosis fact  (197 aa)
 initn: 215 init1:  95 opt: 243  Z-score: 237.3  bits: 51.9 E(85289): 1.8e-06
Smith-Waterman score: 243; 35.7% identity (58.3% similar) in 115 aa overlap (81-186:63-171)

               60        70        80              90       100    
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHH------ISEDGRDCISCKYGQDYS
                                     ::::..      .. :  ::. :. :..:.
NP_001 KGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYT
             40        50        60        70        80        90  

          110       120          130       140       150       160 
pF1KB5 THWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCP
        . .    : ::  :: :   :::.. :: :.:: :.:. . : .    : :  : : : 
NP_001 DKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNSTVCEHCDPC-TKCE
            100       110        120       130       140        150

             170       180       190       200       210       220 
pF1KB5 RGMVKVGDCTPWSDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVA
       .:..:  .::  :. .:  :: :..                                   
NP_001 HGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLLLPIPLIVWGNSGNKFI         
                160         170       180       190                




440 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:48:50 2016 done: Thu Nov  3 17:48:51 2016
 Total Scan time: 10.290 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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