Result of FASTA (omim) for pF1KB5263
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5263, 379 aa
  1>>>pF1KB5263 379 - 379 aa - 379 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.8883+/-0.000627; mu= -27.6872+/- 0.037
 mean_var=723.1821+/-164.945, 0's: 0 Z-trim(115.3): 1301  B-trim: 519 in 1/55
 Lambda= 0.047693
 statistics sampled from 23721 (25591) to 23721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.3), width:  16
 Scan time:  8.200

The best scores are:                                      opt bits E(85289)
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 2542 190.8 4.4e-48
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 2281 172.8 1.1e-42
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 2109 161.0 3.9e-39
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 2109 161.0 3.9e-39
NP_001103361 (OMIM: 601795) mitogen-activated prot ( 335) 1741 135.7 1.6e-31
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1084 90.5 6.7e-18
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1071 89.6 1.2e-17
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 1065 89.2 1.7e-17
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 1026 86.6 1.1e-16
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 1005 85.1 2.9e-16
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367)  955 81.6 3.2e-15
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283)  935 80.1 6.9e-15
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  934 80.6 1.5e-14
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  934 80.6 1.5e-14
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  934 80.6 1.5e-14
XP_011522259 (OMIM: 602521) PREDICTED: mitogen-act ( 677)  906 78.6 4.9e-14
NP_620601 (OMIM: 602521) mitogen-activated protein ( 677)  906 78.6 4.9e-14
XP_011524378 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  894 77.7   8e-14
XP_016881328 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  894 77.7   8e-14
XP_005258356 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  894 77.7   8e-14
XP_011524377 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  894 77.7   8e-14
NP_002738 (OMIM: 176949) mitogen-activated protein ( 587)  894 77.7   8e-14
XP_011524376 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  894 77.7   8e-14
NP_620708 (OMIM: 602896) mitogen-activated protein ( 382)  887 77.0 8.4e-14
NP_620709 (OMIM: 602896) mitogen-activated protein ( 424)  887 77.0   9e-14
XP_016865127 (OMIM: 602896) PREDICTED: mitogen-act ( 424)  887 77.0   9e-14
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  884 76.8 9.7e-14
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297)  880 76.4 9.9e-14
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301)  880 76.4   1e-13
XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  884 76.8   1e-13
XP_016863918 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  884 76.8   1e-13
XP_016863920 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  884 76.8   1e-13
XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  884 76.8   1e-13
NP_002744 (OMIM: 602897) mitogen-activated protein ( 422)  884 76.8   1e-13
XP_016863921 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  884 76.8   1e-13
XP_011530423 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_016863912 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_016863914 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_016863915 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_016863913 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_006714331 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13
XP_011530422 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  884 76.8   1e-13


>>NP_002737 (OMIM: 601795) mitogen-activated protein kin  (379 aa)
 initn: 2542 init1: 2542 opt: 2542  Z-score: 984.3  bits: 190.8 E(85289): 4.4e-48
Smith-Waterman score: 2542; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)

               10        20        30        40        50        60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
              310       320       330       340       350       360

              370         
pF1KB5 KELIFQETARFQPGVLEAP
       :::::::::::::::::::
NP_002 KELIFQETARFQPGVLEAP
              370         

>>NP_001035145 (OMIM: 601795) mitogen-activated protein   (357 aa)
 initn: 2277 init1: 2277 opt: 2281  Z-score: 887.5  bits: 172.8 E(85289): 1.1e-42
Smith-Waterman score: 2281; 98.8% identity (99.4% similar) in 345 aa overlap (1-345:1-344)

               10        20        30        40        50        60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
       ::::::::::::::::::::::::::::::::::::::: :.. :               
NP_001 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSPAAVGLGAGEQGGT  
              310       320       330        340       350         

              370         
pF1KB5 KELIFQETARFQPGVLEAP

>>NP_002736 (OMIM: 176948) mitogen-activated protein kin  (360 aa)
 initn: 2138 init1: 2105 opt: 2109  Z-score: 823.5  bits: 161.0 E(85289): 3.9e-39
Smith-Waterman score: 2109; 86.5% identity (94.4% similar) in 356 aa overlap (19-374:8-357)

               10        20        30        40        50        60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
                         :.::      :::.:: ::::::::.:.:::::::::: :::
NP_002            MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
                          10              20        30        40   

               70        80        90       100       110       120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
       :.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_002 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
            50        60        70        80        90       100   

              130       140       150       160       170       180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
       ::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_002 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
           110       120       130       140       150       160   

              190       200       210       220       230       240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       :::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
           170       180       190       200       210       220   

              250       260       270       280       290       300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
       ::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
           230       240       250       260       270       280   

              310       320       330       340       350       360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
       ::::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_002 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
           290       300       310       320       330       340   

              370         
pF1KB5 KELIFQETARFQPGVLEAP
       :::::.::::::::     
NP_002 KELIFEETARFQPGYRS  
           350       360  

>>NP_620407 (OMIM: 176948) mitogen-activated protein kin  (360 aa)
 initn: 2138 init1: 2105 opt: 2109  Z-score: 823.5  bits: 161.0 E(85289): 3.9e-39
Smith-Waterman score: 2109; 86.5% identity (94.4% similar) in 356 aa overlap (19-374:8-357)

               10        20        30        40        50        60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
                         :.::      :::.:: ::::::::.:.:::::::::: :::
NP_620            MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
                          10              20        30        40   

               70        80        90       100       110       120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
       :.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_620 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
            50        60        70        80        90       100   

              130       140       150       160       170       180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
       ::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_620 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
           110       120       130       140       150       160   

              190       200       210       220       230       240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       :::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_620 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
           170       180       190       200       210       220   

              250       260       270       280       290       300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
       ::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_620 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
           230       240       250       260       270       280   

              310       320       330       340       350       360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
       ::::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_620 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
           290       300       310       320       330       340   

              370         
pF1KB5 KELIFQETARFQPGVLEAP
       :::::.::::::::     
NP_620 KELIFEETARFQPGYRS  
           350       360  

>>NP_001103361 (OMIM: 601795) mitogen-activated protein   (335 aa)
 initn: 1776 init1: 1741 opt: 1741  Z-score: 687.1  bits: 135.7 E(85289): 1.6e-31
Smith-Waterman score: 2152; 88.4% identity (88.4% similar) in 379 aa overlap (1-379:1-335)

               10        20        30        40        50        60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
       ::::::::::::::::::                                          
NP_001 NRPIFPGKHYLDQLNHIL------------------------------------------
              250                                                  

              310       320       330       340       350       360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
        260       270       280       290       300       310      

              370         
pF1KB5 KELIFQETARFQPGVLEAP
       :::::::::::::::::::
NP_001 KELIFQETARFQPGVLEAP
        320       330     

>>NP_620603 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1074 init1: 601 opt: 1158  Z-score: 465.7  bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)

          10        20        30        40        50        60     
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
                                     :::: .:  .. ::.::::.::::  ..  
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

          70         80        90       100       110        120   
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
        .:::::: . :.  :  .:::::..:: .:.:.:.:.:.:::: ..    ...::.: :
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
       80        90       100       110       120       130        

           130        140       150       160       170       180  
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
       :::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_620 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
      140       150       160       170       180       190        

             190       200       210       220       230       240 
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
        :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::. 
NP_620 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
      200       210       220       230       240       250        

             250       260       270       280       290       300 
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
       : .::::.:. ::. :. .::.::   .. .   ..: :.:::: .  : :  ..: .: 
NP_620 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
      260       270       280       290       300       310        

             310       320       330       340       350       360 
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
       .::.:: ::: :.:. ::..  :: ::.: .:.:: :::    :: ::.. . : .::.:
NP_620 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
      320       330       340       350       360       370        

             370                                                   
pF1KB5 ELIFQETARFQPGVLEAP                                          
       : :  :   :.                                                 
NP_620 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
      380       390       400       410       420       430        

>>NP_620602 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1074 init1: 601 opt: 1158  Z-score: 465.7  bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)

          10        20        30        40        50        60     
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
                                     :::: .:  .. ::.::::.::::  ..  
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

          70         80        90       100       110        120   
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
        .:::::: . :.  :  .:::::..:: .:.:.:.:.:.:::: ..    ...::.: :
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
       80        90       100       110       120       130        

           130        140       150       160       170       180  
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
       :::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_620 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
      140       150       160       170       180       190        

             190       200       210       220       230       240 
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
        :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::. 
NP_620 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
      200       210       220       230       240       250        

             250       260       270       280       290       300 
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
       : .::::.:. ::. :. .::.::   .. .   ..: :.:::: .  : :  ..: .: 
NP_620 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
      260       270       280       290       300       310        

             310       320       330       340       350       360 
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
       .::.:: ::: :.:. ::..  :: ::.: .:.:: :::    :: ::.. . : .::.:
NP_620 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
      320       330       340       350       360       370        

             370                                                   
pF1KB5 ELIFQETARFQPGVLEAP                                          
       : :  :   :.                                                 
NP_620 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
      380       390       400       410       420       430        

>>NP_002740 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1074 init1: 601 opt: 1158  Z-score: 465.7  bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)

          10        20        30        40        50        60     
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
                                     :::: .:  .. ::.::::.::::  ..  
NP_002 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

          70         80        90       100       110        120   
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
        .:::::: . :.  :  .:::::..:: .:.:.:.:.:.:::: ..    ...::.: :
NP_002 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
       80        90       100       110       120       130        

           130        140       150       160       170       180  
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
       :::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_002 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
      140       150       160       170       180       190        

             190       200       210       220       230       240 
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
        :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::. 
NP_002 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
      200       210       220       230       240       250        

             250       260       270       280       290       300 
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
       : .::::.:. ::. :. .::.::   .. .   ..: :.:::: .  : :  ..: .: 
NP_002 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
      260       270       280       290       300       310        

             310       320       330       340       350       360 
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
       .::.:: ::: :.:. ::..  :: ::.: .:.:: :::    :: ::.. . : .::.:
NP_002 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
      320       330       340       350       360       370        

             370                                                   
pF1KB5 ELIFQETARFQPGVLEAP                                          
       : :  :   :.                                                 
NP_002 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
      380       390       400       410       420       430        

>>NP_620581 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1045 init1: 516 opt: 1084  Z-score: 442.4  bits: 90.5 E(85289): 6.7e-18
Smith-Waterman score: 1084; 49.1% identity (75.3% similar) in 344 aa overlap (36-377:18-354)

          10        20        30        40        50        60     
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
                                     ..:  :: .:. .: :::: : .:.:    
NP_620              MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
                            10        20        30        40       

          70         80        90       100        110       120   
pF1KB5 TRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRDILR-ASTLEAMRDVYIVQD
        :::.::.: ::.   . .:: ::...: ...::::::. :..  : .:: . :::.:  
NP_620 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
        50        60        70        80        90       100       

           130       140       150       160       170       180   
pF1KB5 LMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC
       :: .:: ...: :.:..::. ...:::::::::::::...::::::::: .:  :.::: 
NP_620 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL
       110       120       130       140       150       160       

           190       200       210       220       230       240   
pF1KB5 DFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP
       :::::: .: :      .: :::::::::::::::   :....::::::::.::.:..: 
NP_620 DFGLARHTDDE------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT
       170             180       190       200       210       220 

           250       260       270       280       290       300   
pF1KB5 IFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKA
       .:::  ..:::. :: ..:.:. : :. : . .::::.::: .  :. .:..:  ..  :
NP_620 LFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLA
             230       240       250       260       270       280 

           310       320       330       340       350       360   
pF1KB5 LDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKEL
       .:::..::... .::::. .:::: :. ::.:: :::::. :.  ..:  ::  .. : :
NP_620 VDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSL
             290       300       310       320        330       340

           370             
pF1KB5 IFQETARFQPGVLEAP    
        ..:.  : :  :.      
NP_620 TYDEVISFVPPPLDQEEMES
              350       360

>>NP_001306 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1032 init1: 503 opt: 1071  Z-score: 437.5  bits: 89.6 E(85289): 1.2e-17
Smith-Waterman score: 1071; 48.0% identity (74.7% similar) in 344 aa overlap (36-377:18-354)

          10        20        30        40        50        60     
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
                                     ..:  :: .:. .: :::: : .:.:    
NP_001              MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
                            10        20        30        40       

          70         80        90       100        110       120   
pF1KB5 TRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRDILR-ASTLEAMRDVYIVQD
        :::.::.: ::.   . .:: ::...: ...::::::. :..  : .:: . :::.:  
NP_001 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
        50        60        70        80        90       100       

           130       140       150       160       170       180   
pF1KB5 LMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC
       :: .:: ...: :.:..::. ...:::::::::::::...::::::::: .:  :.::: 
NP_001 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL
       110       120       130       140       150       160       

           190       200       210       220       230       240   
pF1KB5 DFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP
       :::::: .: :      .: :::::::::::::::   :....::::::::.::.:..: 
NP_001 DFGLARHTDDE------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT
       170             180       190       200       210       220 

           250       260       270       280       290       300   
pF1KB5 IFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKA
       .:::  ...::..:. . :.:    .: . . .::::.::: .  :. .:..:  ..  :
NP_001 LFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLA
             230       240       250       260       270       280 

           310       320       330       340       350       360   
pF1KB5 LDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKEL
       .:::..::... .::::. .:::: :. ::.:: :::::. :.  ..:  ::  .. : :
NP_001 VDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSL
             290       300       310       320        330       340

           370             
pF1KB5 IFQETARFQPGVLEAP    
        ..:.  : :  :.      
NP_001 TYDEVISFVPPPLDQEEMES
              350       360




379 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 16:28:01 2016 done: Thu Nov  3 16:28:02 2016
 Total Scan time:  8.200 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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