Result of FASTA (ccds) for pF1KB5053
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5053, 780 aa
  1>>>pF1KB5053 780 - 780 aa - 780 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6481+/-0.000993; mu= 18.4132+/- 0.060
 mean_var=67.5270+/-13.665, 0's: 0 Z-trim(104.5): 39  B-trim: 315 in 2/49
 Lambda= 0.156076
 statistics sampled from 7914 (7934) to 7914 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.244), width:  16
 Scan time:  3.620

The best scores are:                                      opt bits E(32554)
CCDS14017.1 ACO2 gene_id:50|Hs108|chr22            ( 780) 5255 1192.7       0
CCDS6525.1 ACO1 gene_id:48|Hs108|chr9              ( 889)  352 88.8 4.3e-17
CCDS10302.1 IREB2 gene_id:3658|Hs108|chr15         ( 963)  325 82.7 3.1e-15


>>CCDS14017.1 ACO2 gene_id:50|Hs108|chr22                 (780 aa)
 initn: 5255 init1: 5255 opt: 5255  Z-score: 6387.7  bits: 1192.7 E(32554):    0
Smith-Waterman score: 5255; 100.0% identity (100.0% similar) in 780 aa overlap (1-780:1-780)

               10        20        30        40        50        60
pF1KB5 MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB5 GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB5 VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
              730       740       750       760       770       780

>>CCDS6525.1 ACO1 gene_id:48|Hs108|chr9                   (889 aa)
 initn: 689 init1: 303 opt: 352  Z-score: 420.3  bits: 88.8 E(32554): 4.3e-17
Smith-Waterman score: 737; 28.5% identity (54.4% similar) in 744 aa overlap (91-709:78-818)

               70        80        90       100       110          
pF1KB5 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF--ISSGLSKV
                                     ..: :: .:: :.  :...:  . ....:.
CCDS65 RNCDEFLVKKQDIENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKL
        50        60        70        80        90       100       

               120       130        140           150        160   
pF1KB5 A---------VPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAG-AKYGV
       .          :. .  :: :... . . : :.. .:.    :.: ..::  .. : ...
CCDS65 GGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNM
       110       120       130       140       150       160       

           170                 180       190       200       210   
pF1KB5 GFWKPGSGIIHQIILE----------NYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADA
        .  ::::::::. ::          .: ::  : .::::::    ::: .  :::: .:
CCDS65 RIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSL-VGTDSHTTMIDGLGILGWGVGGIEA
       170       180       190       200        210       220      

           220       230       240       250       260       270   
pF1KB5 VDVMAGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVD
         :: : :  .  :.::: .: :.     .  :..: ..  :   : .: .::. :::: 
CCDS65 EAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVA
        230       240       250       260       270       280      

           280       290       300       310               320     
pF1KB5 SISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRED--------IANLADEFKDH
       ..: .  ::: ::  : :::.. :: ..    :: .:::..          . .  :.: 
CCDS65 QLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDF
        290       300       310       320       330       340      

         330       340       350       360            370          
pF1KB5 LVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGK-----VAEKEGW------P
         :.    . :..:..:. . :  .::  :.    :... :     .. :.:.      :
CCDS65 NDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAP
        350       360       370       380       390       400      

                              380       390        400       410   
pF1KB5 ----------LD----------IRVGLIGSCTNSSYEDMGRSAAV-AKQALAHGLKCKS-
                  :          . .. : ::::.:  ..  .:.. ::.:.  ::.    
CCDS65 EHHNDHKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPY
        410       420       430       440       450       460      

             420       430       440       450             460     
pF1KB5 -QFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDR------KDIKKGEK
        . ...:::  .   ....:    : .::  :.. .:  :::.         . : .:. 
CCDS65 IKTSLSPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDL
        470       480       490       500       510       520      

          470       480        490       500       510        520  
pF1KB5 NTI-VTSYNRNFTGRNDANPETHA-FVTSPEIVTALAIAGTLKFNPETDYL-TGTDGKKF
        .. : : :::: ::  ..:.:.: ...:: .: : :::::.... : . : ... :.. 
CCDS65 VAVGVLSGNRNFEGR--VHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQV
        530       540         550       560       570       580    

              530          540         550       560               
pF1KB5 RLEA--PDADELPKGEFD---PG--QDTYQHPPKDSSGQHVDVSPT-------SQRLQLL
        :.   :  ::.   : .   ::  ...::.    . . .. ..:.       :.   . 
CCDS65 FLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIK
          590       600       610       620       630       640    

      570              580       590       600                     
pF1KB5 EP-------FDKWDGKDLEDLQILIKVKGKCTTDHISAAG------PWLKF---RG----
        :       .:    :.. :  .:...  . :::::: ::      :  ..   ::    
CCDS65 SPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPR
          650       660       670       680       690       700    

      610       620                    630       640       650     
pF1KB5 HLDNISNNLLIGAI-------NIE------NGKANSVRNAVTQEFGPVPDTARYYKKHGI
       .... ..     :.       ::.      : .: .. .  . :.  : :.:. :.. :.
CCDS65 EFNSYGSRRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGL
          710       720       730       740       750       760    

         660       670       680       690       700       710     
pF1KB5 RWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADY
         .:.. ..:: ::::. ::  :  :: .:....:. :::..::  .:..:: .      
CCDS65 PLIVLAGKEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENA
          770       780       790       800       810       820    

         720       730       740       750       760       770     
pF1KB5 NKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRM
                                                                   
CCDS65 DALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMI
          830       840       850       860       870       880    

>>CCDS10302.1 IREB2 gene_id:3658|Hs108|chr15              (963 aa)
 initn: 571 init1: 283 opt: 325  Z-score: 386.9  bits: 82.7 E(32554): 3.1e-15
Smith-Waterman score: 598; 28.3% identity (52.1% similar) in 674 aa overlap (147-709:225-893)

        120       130       140       150       160        170     
pF1KB5 KVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKY-GVGFWKPGSGIIHQ
                                     :.:  .:.  ..  . .:.   ::.:. ::
CCDS10 ENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQ
          200       210       220       230       240       250    

                   180       190       200       210       220     
pF1KB5 IILE----------NYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELK
       : ::          .  .:  . .:::::    .::: .  :::: ..  :: :.:  : 
CCDS10 INLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLT
          260       270        280       290       300       310   

         230       240       250       260       270       280     
pF1KB5 CPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICN
        :.:.: .:::: . . .  ::.: ..  :   : .: .::. : ::...: .  .:: :
CCDS10 LPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIAN
           320       330       340       350       360       370   

         290       300       310               320       330       
pF1KB5 MGAEIGATTSVFPYNHRMKKYLSKTG--------REDIANLADEFKDHLVPDPGCHYDQL
       :  : ::  : :: ..   :.: .::         :   . .  :..    .   .:.:.
CCDS10 MCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQV
           380       390       400       410       420       430   

       340       350                  360             370          
pF1KB5 IEINLSELKPHINGPFTP-----------DLAHPVAE-VG-----KVAEK---------E
       :.:::. . : ..::  :           :.   . : ::      .:::         :
CCDS10 IQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKDIVSIHYE
           440       450       460       470       480       490   

                  380       390        400       410         420   
pF1KB5 G--WPLD---IRVGLIGSCTNSSYEDMGRSAAV-AKQALAHGLKCKSQF--TITPGSEQI
       :  . :.   . .. . ::::.   ..  .:.. ::.:.  ::. :  .  ...::: ..
CCDS10 GSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMV
           500       510       520       530       540       550   

           430       440       450             460        470      
pF1KB5 RATIERDGYAQILRDLGGIVLANACGPCIGQW-DRKD-----IKKGEKNTI-VTSYNRNF
          .  .:    :  ::  ... .:. :.:.    .:     .:.:.  :  . : :.::
CCDS10 THYLSSSGVLPYLSKLGFEIVGYGCSICVGNTAPLSDAVLNAVKQGDLVTCGILSGNKNF
           560       570       580       590       600       610   

        480       490       500       510         520         530  
pF1KB5 TGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTD--GKKFRLEA--PDADEL
        ::   .     ...:: .:.: :::::.... .:. : :::  ::.. :.   :. .:.
CCDS10 EGRL-CDCVRANYLASPPLVVAYAIAGTVNIDFQTEPL-GTDPTGKNIYLHDIWPSREEV
            620       630       640       650        660       670 

                    540               550       560       570      
pF1KB5 PKGE--------FDPGQDTYQHPPK--------DSSGQHVDVSPTSQRLQLLEPFDKWDG
        . :        :   .:  .   :        ::     :.. :  :   .  :::   
CCDS10 HRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSF--FDKLTK
             680       690       700       710       720           

             580       590       600       610           620       
pF1KB5 KDL-----EDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLL----IGAINIENG
       . .     :. ..:. .  . :::::: ::   .  .    ..:  :    ... . . :
CCDS10 EPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRG
     730       740       750       760       770       780         

        630         640                          650       660     
pF1KB5 K-ANSVRN--AVTQEFG-----PVPDT--------------ARYYKKHGIRWVVIGDENY
       . :  .:.  :  . :.     :.: :              :. :.:.::  .... ..:
CCDS10 NDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKY
     790       800       810       820       830       840         

         670       680       690       700       710       720     
pF1KB5 GEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLT
       : :.::. ::  :  :: .:....:. .::. .:   :. :: :                
CCDS10 GSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRET
     850       860       870       880       890       900         

         730       740       750       760       770       780
pF1KB5 IQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
                                                              
CCDS10 FSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS 
     910       920       930       940       950       960    




780 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 15:50:09 2016 done: Thu Nov  3 15:50:10 2016
 Total Scan time:  3.620 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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