Result of FASTA (omim) for pF1KB3707
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3707, 999 aa
  1>>>pF1KB3707 999 - 999 aa - 999 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.5492+/-0.000478; mu= -2.4290+/- 0.030
 mean_var=262.3750+/-53.342, 0's: 0 Z-trim(118.3): 35  B-trim: 306 in 1/56
 Lambda= 0.079180
 statistics sampled from 31167 (31202) to 31167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.366), width:  16
 Scan time: 15.370

The best scores are:                                      opt bits E(85289)
XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 6453 751.3 5.8e-216
XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 6453 751.3 5.8e-216
NP_001124463 (OMIM: 601746) hypoxia up-regulated p ( 999) 6453 751.3 5.8e-216
NP_006380 (OMIM: 601746) hypoxia up-regulated prot ( 999) 6453 751.3 5.8e-216
XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 6441 749.9 1.5e-215
XP_016875853 (OMIM: 610703) PREDICTED: heat shock  ( 736)  463 67.0 4.3e-10
XP_011533190 (OMIM: 610703) PREDICTED: heat shock  ( 780)  463 67.0 4.5e-10
NP_001273434 (OMIM: 610703) heat shock protein 105 ( 782)  463 67.0 4.5e-10
XP_016875852 (OMIM: 610703) PREDICTED: heat shock  ( 807)  410 61.0 3.1e-08
NP_001273432 (OMIM: 610703) heat shock protein 105 ( 814)  410 61.0 3.1e-08
XP_016875850 (OMIM: 610703) PREDICTED: heat shock  ( 851)  410 61.0 3.2e-08
NP_006635 (OMIM: 610703) heat shock protein 105 kD ( 858)  410 61.0 3.2e-08
NP_005518 (OMIM: 140559) heat shock 70 kDa protein ( 641)  406 60.4 3.5e-08
NP_002146 (OMIM: 140555) heat shock 70 kDa protein ( 643)  406 60.4 3.5e-08
NP_694881 (OMIM: 600816) heat shock cognate 71 kDa ( 493)  396 59.2 6.2e-08
NP_006588 (OMIM: 600816) heat shock cognate 71 kDa ( 646)  396 59.3 7.8e-08
XP_011541100 (OMIM: 600816) PREDICTED: heat shock  ( 646)  396 59.3 7.8e-08
NP_005336 (OMIM: 140550) heat shock 70 kDa protein ( 641)  392 58.8 1.1e-07
NP_005337 (OMIM: 603012) heat shock 70 kDa protein ( 641)  392 58.8 1.1e-07
NP_068814 (OMIM: 140560) heat shock-related 70 kDa ( 639)  390 58.6 1.2e-07
NP_005338 (OMIM: 138120) 78 kDa glucose-regulated  ( 654)  383 57.8 2.2e-07
NP_002145 (OMIM: 601113) heat shock 70 kDa protein ( 840)  383 57.9 2.7e-07
NP_004125 (OMIM: 182170,600548,616854) stress-70 p ( 679)  366 55.9 8.7e-07
NP_008879 (OMIM: 601100) heat shock 70 kDa protein ( 471)  331 51.8   1e-05
XP_016875851 (OMIM: 610703) PREDICTED: heat shock  ( 809)  336 52.5 1.1e-05
XP_005266293 (OMIM: 610703) PREDICTED: heat shock  ( 816)  336 52.5 1.1e-05
XP_011533189 (OMIM: 610703) PREDICTED: heat shock  ( 853)  336 52.5 1.1e-05
NP_001273433 (OMIM: 610703) heat shock protein 105 ( 860)  336 52.5 1.1e-05
NP_057383 (OMIM: 610369) heat shock 70 kDa protein ( 509)  272 45.1  0.0012


>>XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up-regu  (999 aa)
 initn: 6453 init1: 6453 opt: 6453  Z-score: 3998.2  bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

              970       980       990         
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :::::::::::::::::::::::::::::::::::::::
XP_016 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990         

>>XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up-regu  (999 aa)
 initn: 6453 init1: 6453 opt: 6453  Z-score: 3998.2  bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

              970       980       990         
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :::::::::::::::::::::::::::::::::::::::
XP_016 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990         

>>NP_001124463 (OMIM: 601746) hypoxia up-regulated prote  (999 aa)
 initn: 6453 init1: 6453 opt: 6453  Z-score: 3998.2  bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

              970       980       990         
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :::::::::::::::::::::::::::::::::::::::
NP_001 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990         

>>NP_006380 (OMIM: 601746) hypoxia up-regulated protein   (999 aa)
 initn: 6453 init1: 6453 opt: 6453  Z-score: 3998.2  bits: 751.3 E(85289): 5.8e-216
Smith-Waterman score: 6453; 100.0% identity (100.0% similar) in 999 aa overlap (1-999:1-999)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

              970       980       990         
pF1KB3 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :::::::::::::::::::::::::::::::::::::::
NP_006 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990         

>>XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up-regu  (1000 aa)
 initn: 6439 init1: 6199 opt: 6441  Z-score: 3990.8  bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

               970       980       990         
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990      1000

>>XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up-regu  (1000 aa)
 initn: 6439 init1: 6199 opt: 6441  Z-score: 3990.8  bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

               970       980       990         
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990      1000

>>XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up-regu  (1000 aa)
 initn: 6439 init1: 6199 opt: 6441  Z-score: 3990.8  bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

               970       980       990         
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :: :::::::::::::::::::::::::::::::::::::
XP_005 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990      1000

>>XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up-regu  (1000 aa)
 initn: 6439 init1: 6199 opt: 6441  Z-score: 3990.8  bits: 749.9 E(85289): 1.5e-215
Smith-Waterman score: 6441; 99.9% identity (99.9% similar) in 1000 aa overlap (1-999:1-1000)

               10        20        30        40        50        60
pF1KB3 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
              910       920       930       940       950       960

               970       980       990         
pF1KB3 ET-GSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
       :: :::::::::::::::::::::::::::::::::::::
XP_016 ETAGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
              970       980       990      1000

>>XP_016875853 (OMIM: 610703) PREDICTED: heat shock prot  (736 aa)
 initn: 554 init1: 205 opt: 463  Z-score: 302.2  bits: 67.0 E(85289): 4.3e-10
Smith-Waterman score: 658; 24.9% identity (50.6% similar) in 927 aa overlap (33-940:1-728)

             10        20        30        40        50        60  
pF1KB3 DKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNK
                                     ..:...:.::.:  .:... :  .: . :.
XP_016                               MSVVGLDVGSQSCYIAVARAG-GIETIANE
                                             10        20          

             70        80        90       100       110       120  
pF1KB3 ESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPE
        : : :: ....  ..: .: .: .. : . . :.  :... :.  ..: .         
XP_016 FSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFI---------
      30        40        50        60        70        80         

            130       140       150       160       170       180  
pF1KB3 HELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQ
              :..                        ...:. :..  :.:.. . . :..  
XP_016 -------QKE------------------------KENLSYDLV--PLKNGGVGIKVMYMG
                                              90         100       

            190       200       210       220       230       240  
pF1KB3 AERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTI
        :.           ..: :.    ::  :.        .. ::.:    .. .  : :.:
XP_016 EEHL----------FSVEQI----TAMLLT-------KLKETAEN----SLKKPVTDCVI
       110                     120              130           140  

            250       260       270       280       290       300  
pF1KB3 VTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVREN
                        .. :..::  ::: ... .: :.. . :. . :     :.. .
XP_016 -----------------SVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSK
                             150       160       170           180 

            310       320        330       340       350       360 
pF1KB3 PRAMAKLLREANRLKTVLSANADHMA-QIEGLMDDVDFKAKVTRVEFEELCADLFERVPG
        ::. .: .: ..:: ..:.:.  .  .:: .:.: : ..:..: .::::::.:....  
XP_016 IRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEV
             190       200       210       220       230       240 

             370       380       390       400       410       420 
pF1KB3 PVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVY
       :. . :..........  : .::::::.: :.: . :  ::. .. ..:::::.: : . 
XP_016 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKD-ISTTLNADEAVARGCAL
             250       260       270       280        290       300

             430       440       450       460       470       480 
pF1KB3 QAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKV
       : : :: ::::. : : ::: .:: . .... :.  :.: .       :::    :  ::
XP_016 QCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV-------FSRNHAAPFSKV
              310       320       330       340              350   

             490        500        510       520       530         
pF1KB3 ITFNRYSHDFNFHINYGD-LGFLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGI
       .:: : .  :...  :.:  :   ::  .  :  ::... :            : :.. .
XP_016 LTFLRRG-PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQK------------DGEKSRV
           360        370       380       390                   400

     540       550       560       570       580       590         
pF1KB3 KAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTD
       :..  ..  :..... .     ..::    ::       : .::                
XP_016 KVKVRVNTHGIFTISTA-----SMVEKVPTEE-------NEMSS----------------
              410            420              430                  

     600       610       620       630       640       650         
pF1KB3 TVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGD
                                  :: .:  .: :: .:  ::.       ::.  .
XP_016 ---------------------------EADMECLNQRPPENPDTDAN-------EKKVDQ
                                       440       450               

     660       670       680       690       700       710         
pF1KB3 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS
         ::.::. :.              . . :  .  .: ..: .:  :..    : :.   
XP_016 PPEAKKPKIKVV-------------NVELPI-EANLVWQLGKDL--LNMYIETEGKMI--
      460       470                     480         490       500  

     720       730       740       750       760       770         
pF1KB3 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS
          .::     ::: ::. : :..: ...: .:::  : :..   :......   :. . 
XP_016 ---MQD----KLEK-ERNDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTETE
                      510       520       530        540       550 

     780       790       800       810       820       830         
pF1KB3 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGA
        :: .::   .     .:: :: :.   .  : .: .. :. .  : . :.: . .    
XP_016 DWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADF
             560       570       580       590       600       610 

     840       850       860       870       880       890         
pF1KB3 RLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALD
       :   :  . . : ::  .:: .::.  : : ..  :::    . ::. ...:..:.  :.
XP_016 RNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELN
             620       630       640       650       660       670 

     900         910                     920       930       940   
pF1KB3 REVQYLLN--KAKFTKPR----PR-P---------KDKNGTRAEPPLNASASDQGEKVIP
          . ...  : :. .:.    :  :         .:::.  :::: . .    .::   
XP_016 NTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSV
             680       690       700       710       720       730 

           950       960       970       980       990         
pF1KB3 PAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
                                                               
XP_016 NMDLD                                                   
                                                               

>>XP_011533190 (OMIM: 610703) PREDICTED: heat shock prot  (780 aa)
 initn: 469 init1: 205 opt: 463  Z-score: 301.8  bits: 67.0 E(85289): 4.5e-10
Smith-Waterman score: 764; 25.3% identity (53.4% similar) in 929 aa overlap (33-940:1-772)

             10        20        30        40        50        60  
pF1KB3 DKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNK
                                     ..:...:.::.:  .:... :  .: . :.
XP_011                               MSVVGLDVGSQSCYIAVARAG-GIETIANE
                                             10        20          

             70        80        90       100       110       120  
pF1KB3 ESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPE
        : : :: ....  ..: .: .: .. : . . :.  :... :.  ..: .         
XP_011 FSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFI---------
      30        40        50        60        70        80         

            130       140       150       160       170       180  
pF1KB3 HELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQ
              :..                        ...:. :..  :.:.. . . :..  
XP_011 -------QKE------------------------KENLSYDLV--PLKNGGVGIKVMYMG
                                              90         100       

            190       200       210       220       230       240  
pF1KB3 AERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTI
        :.           ..: :.    ::  :.        .. ::.:    .. .  : :.:
XP_011 EEHL----------FSVEQI----TAMLLT-------KLKETAEN----SLKKPVTDCVI
       110                     120              130           140  

            250       260       270       280       290       300  
pF1KB3 VTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVREN
                        .. :..::  ::: ... .: :.. . :. . :     :.. .
XP_011 -----------------SVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSK
                             150       160       170           180 

            310       320        330       340       350       360 
pF1KB3 PRAMAKLLREANRLKTVLSANADHMA-QIEGLMDDVDFKAKVTRVEFEELCADLFERVPG
        ::. .: .: ..:: ..:.:.  .  .:: .:.: : ..:..: .::::::.:....  
XP_011 IRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEV
             190       200       210       220       230       240 

             370       380       390       400       410       420 
pF1KB3 PVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVY
       :. . :..........  : .::::::.: :.: . :  ::. .. ..:::::.: : . 
XP_011 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKD-ISTTLNADEAVARGCAL
             250       260       270       280        290       300

             430       440       450       460       470       480 
pF1KB3 QAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKV
       : : :: ::::. : : ::: .:: . .... :.  :.: .       :::    :  ::
XP_011 QCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV-------FSRNHAAPFSKV
              310       320       330       340              350   

             490        500        510       520       530         
pF1KB3 ITFNRYSHDFNFHINYGD-LGFLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGI
       .:: : .  :...  :.:  :   ::  .  :  ::... :            : :.. .
XP_011 LTFLRRG-PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQK------------DGEKSRV
           360        370       380       390                   400

     540       550       560       570       580       590         
pF1KB3 KAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTD
       :..  ..  :..... .     ..::    ::. ... ..          .::. .:   
XP_011 KVKVRVNTHGIFTISTA-----SMVEKVPTEENEMSSEADMECLNQRPPENPDTDKN---
              410            420       430       440       450     

     600       610       620       630       640         650       
pF1KB3 TVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPE--PKGDATPEGEKATEKEN
        ::...        .: : : ... .:.   . ...:: ::   . .  :...::.::. 
XP_011 -VQQDN--------SEAGTQPQVQTDAQ---QTSQSPPSPELTSEENKIPDADKANEKKV
                     460       470          480       490       500

       660       670       680       690       700       710       
pF1KB3 GDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLA
        .  ::.::. :.              . . :  .  .: ..: .:  :..    : :. 
XP_011 DQPPEAKKPKIKVV-------------NVELPI-EANLVWQLGKDL--LNMYIETEGKMI
              510                    520        530         540    

       720       730       740       750       760       770       
pF1KB3 QSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSA
            .::     ::: ::. : :..: ...: .:::  : :..   :......   :. 
XP_011 -----MQD----KLEK-ERNDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTE
                   550        560       570        580       590   

       780       790       800       810       820       830       
pF1KB3 ASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLK
       .  :: .::   .     .:: :: :.   .  : .: .. :. .  : . :.: . .  
XP_011 TEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAA
           600       610       620       630       640       650   

       840       850       860       870       880       890       
pF1KB3 GARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMA
         :   :  . . : ::  .:: .::.  : : ..  :::    . ::. ...:..:.  
XP_011 DFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKE
           660       670       680       690       700       710   

       900         910                     920       930       940 
pF1KB3 LDREVQYLLN--KAKFTKPR----PR-P---------KDKNGTRAEPPLNASASDQGEKV
       :.   . ...  : :. .:.    :  :         .:::.  :::: . .    .:: 
XP_011 LNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKN
           720       730       740       750       760       770   

             950       960       970       980       990         
pF1KB3 IPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
                                                                 
XP_011 SVNMDLD                                                   
           780                                                   




999 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:46:35 2016 done: Thu Nov  3 13:46:38 2016
 Total Scan time: 15.370 Total Display time:  0.420

Function used was FASTA [36.3.4 Apr, 2011]
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