Result of FASTA (omim) for pF1KB3699
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3699, 851 aa
  1>>>pF1KB3699 851 - 851 aa - 851 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0146+/-0.00042; mu= 13.1398+/- 0.026
 mean_var=122.7096+/-24.411, 0's: 0 Z-trim(114.9): 67  B-trim: 75 in 1/54
 Lambda= 0.115780
 statistics sampled from 24894 (24961) to 24894 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.293), width:  16
 Scan time: 14.140

The best scores are:                                      opt bits E(85289)
NP_005410 (OMIM: 600556,616636) signal transducer  ( 851) 5722 967.8       0
XP_011536999 (OMIM: 600556,616636) PREDICTED: sign ( 859) 5696 963.4       0
NP_938146 (OMIM: 600556,616636) signal transducer  ( 847) 5674 959.7       0
XP_011537000 (OMIM: 600556,616636) PREDICTED: sign ( 855) 5648 955.4       0
XP_016875393 (OMIM: 600556,616636) PREDICTED: sign ( 607) 3976 676.0 1.4e-193
XP_011537002 (OMIM: 600556,616636) PREDICTED: sign ( 615) 3950 671.7 2.9e-192
XP_011537001 (OMIM: 600556,616636) PREDICTED: sign ( 592) 3843 653.8 6.6e-187
XP_005269168 (OMIM: 600556,616636) PREDICTED: sign ( 464) 2957 505.7 1.9e-142
NP_644671 (OMIM: 600555,613796,614162,614892) sign ( 712) 1849 320.8 1.4e-86
XP_006712781 (OMIM: 600555,613796,614162,614892) P ( 750) 1849 320.8 1.5e-86
NP_009330 (OMIM: 600555,613796,614162,614892) sign ( 750) 1849 320.8 1.5e-86
XP_016860272 (OMIM: 600555,613796,614162,614892) P ( 752) 1849 320.8 1.5e-86
NP_003142 (OMIM: 600558,612253) signal transducer  ( 748) 1767 307.1   2e-82
XP_011510007 (OMIM: 600558,612253) PREDICTED: sign ( 748) 1767 307.1   2e-82
XP_006712782 (OMIM: 600558,612253) PREDICTED: sign ( 748) 1767 307.1   2e-82
NP_001230764 (OMIM: 600558,612253) signal transduc ( 748) 1767 307.1   2e-82
NP_003141 (OMIM: 102582,147060,615952) signal tran ( 769) 1445 253.3 3.1e-66
XP_005257673 (OMIM: 102582,147060,615952) PREDICTE ( 769) 1445 253.3 3.1e-66
XP_016880464 (OMIM: 102582,147060,615952) PREDICTE ( 769) 1445 253.3 3.1e-66
XP_005257674 (OMIM: 102582,147060,615952) PREDICTE ( 770) 1445 253.3 3.1e-66
XP_011523447 (OMIM: 102582,147060,615952) PREDICTE ( 770) 1445 253.3 3.1e-66
NP_644805 (OMIM: 102582,147060,615952) signal tran ( 770) 1445 253.3 3.1e-66
XP_016880465 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880462 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880463 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880461 (OMIM: 102582,147060,615952) PREDICTE ( 722) 1443 253.0 3.7e-66
XP_011523448 (OMIM: 102582,147060,615952) PREDICTE ( 722) 1443 253.0 3.7e-66
NP_998827 (OMIM: 102582,147060,615952) signal tran ( 722) 1443 253.0 3.7e-66
XP_016860273 (OMIM: 600558,612253) PREDICTED: sign ( 500) 1017 181.7 7.3e-45
XP_016880466 (OMIM: 245590,604260) PREDICTED: sign ( 693)  583 109.3 6.3e-23
NP_036580 (OMIM: 245590,604260) signal transducer  ( 787)  583 109.3   7e-23
XP_005257681 (OMIM: 601511) PREDICTED: signal tran ( 761)  561 105.6 8.7e-22
NP_001275648 (OMIM: 601511) signal transducer and  ( 764)  561 105.6 8.7e-22
NP_001275647 (OMIM: 601511) signal transducer and  ( 794)  561 105.7   9e-22
NP_003143 (OMIM: 601511) signal transducer and act ( 794)  561 105.7   9e-22
NP_001171552 (OMIM: 601512) signal transducer and  ( 737)  530 100.5 3.1e-20
NP_001171551 (OMIM: 601512) signal transducer and  ( 737)  530 100.5 3.1e-20
NP_001171549 (OMIM: 601512) signal transducer and  ( 847)  530 100.5 3.4e-20
NP_001171550 (OMIM: 601512) signal transducer and  ( 847)  530 100.5 3.4e-20
NP_003144 (OMIM: 601512) signal transducer and act ( 847)  530 100.5 3.4e-20
XP_006719638 (OMIM: 601512) PREDICTED: signal tran ( 847)  530 100.5 3.4e-20
NP_001275649 (OMIM: 601511) signal transducer and  ( 763)  345 69.6 6.3e-11
XP_011537010 (OMIM: 601512) PREDICTED: signal tran ( 755)  303 62.6 8.1e-09
XP_011537011 (OMIM: 601512) PREDICTED: signal tran ( 755)  303 62.6 8.1e-09
XP_011537005 (OMIM: 601512) PREDICTED: signal tran ( 865)  303 62.6 9.1e-09
XP_011537007 (OMIM: 601512) PREDICTED: signal tran ( 865)  303 62.6 9.1e-09
XP_011537008 (OMIM: 601512) PREDICTED: signal tran ( 865)  303 62.6 9.1e-09
XP_011537006 (OMIM: 601512) PREDICTED: signal tran ( 865)  303 62.6 9.1e-09
XP_011537009 (OMIM: 601512) PREDICTED: signal tran ( 865)  303 62.6 9.1e-09
XP_005257683 (OMIM: 245590,604260) PREDICTED: sign ( 497)  253 54.1 1.9e-06


>>NP_005410 (OMIM: 600556,616636) signal transducer and   (851 aa)
 initn: 5722 init1: 5722 opt: 5722  Z-score: 5170.5  bits: 967.8 E(85289):    0
Smith-Waterman score: 5722; 100.0% identity (100.0% similar) in 851 aa overlap (1-851:1-851)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
              790       800       810       820       830       840

              850 
pF1KB3 YTDGPLMPSDF
       :::::::::::
NP_005 YTDGPLMPSDF
              850 

>>XP_011536999 (OMIM: 600556,616636) PREDICTED: signal t  (859 aa)
 initn: 3223 init1: 3172 opt: 5696  Z-score: 5146.9  bits: 963.4 E(85289):    0
Smith-Waterman score: 5696; 99.1% identity (99.1% similar) in 859 aa overlap (1-851:1-859)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
              430       440       450       460       470       480

                      490       500       510       520       530  
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
              490       500       510       520       530       540

            540       550       560       570       580       590  
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
              550       560       570       580       590       600

            600       610       620       630       640       650  
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
              610       620       630       640       650       660

            660       670       680       690       700       710  
pF1KB3 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
              670       680       690       700       710       720

            720       730       740       750       760       770  
pF1KB3 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
              730       740       750       760       770       780

            780       790       800       810       820       830  
pF1KB3 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
              790       800       810       820       830       840

            840       850 
pF1KB3 YVSRPSHFYTDGPLMPSDF
       :::::::::::::::::::
XP_011 YVSRPSHFYTDGPLMPSDF
              850         

>>NP_938146 (OMIM: 600556,616636) signal transducer and   (847 aa)
 initn: 5025 init1: 5025 opt: 5674  Z-score: 5127.2  bits: 959.7 E(85289):    0
Smith-Waterman score: 5674; 99.5% identity (99.5% similar) in 851 aa overlap (1-851:1-847)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       :::::::::::::::::::::::::::::::::::    :::::::::::::::::::::
NP_938 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ----DPTQLAEMIFNLLLEEKRILI
               70        80        90           100       110      

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
        300       310       320       330       340       350      

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
        360       370       380       390       400       410      

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
        420       430       440       450       460       470      

              490       500       510       520       530       540
pF1KB3 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
        480       490       500       510       520       530      

              550       560       570       580       590       600
pF1KB3 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
        540       550       560       570       580       590      

              610       620       630       640       650       660
pF1KB3 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
        600       610       620       630       640       650      

              670       680       690       700       710       720
pF1KB3 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
        660       670       680       690       700       710      

              730       740       750       760       770       780
pF1KB3 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
        720       730       740       750       760       770      

              790       800       810       820       830       840
pF1KB3 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
        780       790       800       810       820       830      

              850 
pF1KB3 YTDGPLMPSDF
       :::::::::::
NP_938 YTDGPLMPSDF
        840       

>>XP_011537000 (OMIM: 600556,616636) PREDICTED: signal t  (855 aa)
 initn: 3236 init1: 2572 opt: 5648  Z-score: 5103.6  bits: 955.4 E(85289):    0
Smith-Waterman score: 5648; 98.6% identity (98.6% similar) in 859 aa overlap (1-851:1-855)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       :::::::::::::::::::::::::::::::::::    :::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ----DPTQLAEMIFNLLLEEKRILI
               70        80        90           100       110      

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
        300       310       320       330       340       350      

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
        360       370       380       390       400       410      

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
        420       430       440       450       460       470      

                      490       500       510       520       530  
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
        480       490       500       510       520       530      

            540       550       560       570       580       590  
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
        540       550       560       570       580       590      

            600       610       620       630       640       650  
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
        600       610       620       630       640       650      

            660       670       680       690       700       710  
pF1KB3 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
        660       670       680       690       700       710      

            720       730       740       750       760       770  
pF1KB3 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
        720       730       740       750       760       770      

            780       790       800       810       820       830  
pF1KB3 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
        780       790       800       810       820       830      

            840       850 
pF1KB3 YVSRPSHFYTDGPLMPSDF
       :::::::::::::::::::
XP_011 YVSRPSHFYTDGPLMPSDF
        840       850     

>>XP_016875393 (OMIM: 600556,616636) PREDICTED: signal t  (607 aa)
 initn: 3976 init1: 3976 opt: 3976  Z-score: 3596.4  bits: 676.0 E(85289): 1.4e-193
Smith-Waterman score: 3976; 100.0% identity (100.0% similar) in 590 aa overlap (262-851:18-607)

             240       250       260       270       280       290 
pF1KB3 LPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
                                     ::::::::::::::::::::::::::::::
XP_016              MVRGTTPTLVLAMRCDLFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
                            10        20        30        40       

             300       310       320       330       340       350 
pF1KB3 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
        50        60        70        80        90       100       

             360       370       380       390       400       410 
pF1KB3 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
       110       120       130       140       150       160       

             420       430       440       450       460       470 
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       170       180       190       200       210       220       

             480       490       500       510       520       530 
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
       230       240       250       260       270       280       

             540       550       560       570       580       590 
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
       290       300       310       320       330       340       

             600       610       620       630       640       650 
pF1KB3 KTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLL
       350       360       370       380       390       400       

             660       670       680       690       700       710 
pF1KB3 TEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLE
       410       420       430       440       450       460       

             720       730       740       750       760       770 
pF1KB3 LKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVS
       470       480       490       500       510       520       

             780       790       800       810       820       830 
pF1KB3 QTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDE
       530       540       550       560       570       580       

             840       850 
pF1KB3 VYVSRPSHFYTDGPLMPSDF
       ::::::::::::::::::::
XP_016 VYVSRPSHFYTDGPLMPSDF
       590       600       

>>XP_011537002 (OMIM: 600556,616636) PREDICTED: signal t  (615 aa)
 initn: 2572 init1: 2572 opt: 3950  Z-score: 3572.9  bits: 671.7 E(85289): 2.9e-192
Smith-Waterman score: 3950; 98.7% identity (98.7% similar) in 598 aa overlap (262-851:18-615)

             240       250       260       270       280       290 
pF1KB3 LPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
                                     ::::::::::::::::::::::::::::::
XP_011              MVRGTTPTLVLAMRCDLFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
                            10        20        30        40       

             300       310       320       330       340       350 
pF1KB3 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
        50        60        70        80        90       100       

             360       370       380       390       400       410 
pF1KB3 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
       110       120       130       140       150       160       

             420       430       440       450       460       470 
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       170       180       190       200       210       220       

             480               490       500       510       520   
pF1KB3 FNLLSPNLQ--------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNK
       :::::::::        :::::::::::::::::::::::::::::::::::::::::::
XP_011 FNLLSPNLQPTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNK
       230       240       250       260       270       280       

           530       540       550       560       570       580   
pF1KB3 LFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSR
       290       300       310       320       330       340       

           590       600       610       620       630       640   
pF1KB3 SQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTE
       350       360       370       380       390       400       

           650       660       670       680       690       700   
pF1KB3 IIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQV
       410       420       430       440       450       460       

           710       720       730       740       750       760   
pF1KB3 DELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVI
       470       480       490       500       510       520       

           770       780       790       800       810       820   
pF1KB3 EPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLL
       530       540       550       560       570       580       

           830       840       850 
pF1KB3 AGQNTVDEVYVSRPSHFYTDGPLMPSDF
       ::::::::::::::::::::::::::::
XP_011 AGQNTVDEVYVSRPSHFYTDGPLMPSDF
       590       600       610     

>>XP_011537001 (OMIM: 600556,616636) PREDICTED: signal t  (592 aa)
 initn: 3867 init1: 3172 opt: 3843  Z-score: 3476.5  bits: 653.8 E(85289): 6.6e-187
Smith-Waterman score: 3843; 98.5% identity (98.6% similar) in 584 aa overlap (1-576:1-584)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
              430       440       450       460       470       480

                      490       500       510       520       530  
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
              490       500       510       520       530       540

            540       550       560       570       580       590  
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
       :::::::::::::::::::::::::::::::::::::::::::.                
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGKKKKCCSSV        
              550       560       570       580       590          

            600       610       620       630       640       650  
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT

>>XP_005269168 (OMIM: 600556,616636) PREDICTED: signal t  (464 aa)
 initn: 2957 init1: 2957 opt: 2957  Z-score: 2678.2  bits: 505.7 E(85289): 1.9e-142
Smith-Waterman score: 2957; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
       :::::::::::::::::::::::::::                                 
XP_005 PLGVTEELHIISFTVKYTYQGLKQELKVSENGGQGERKQLWKKA                
              430       440       450       460                    

>>NP_644671 (OMIM: 600555,613796,614162,614892) signal t  (712 aa)
 initn: 1423 init1: 512 opt: 1849  Z-score: 1675.3  bits: 320.8 E(85289): 1.4e-86
Smith-Waterman score: 1851; 43.7% identity (71.6% similar) in 718 aa overlap (1-699:1-710)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       :.::  ::.::: : .:.::::. :. :..:::::: :.: :.:..::  .: : ::. :
NP_644 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF
               10        20         30        40          50       

               70        80        90        100       110         
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL
         .:.::. . .: : . ...:::::.::  :..:  :..:: :.. .:.. : ::..::
NP_644 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL
        60        70         80        90       100       110      

     120       130       140       150          160       170      
pF1KB3 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR--AM-MEKLVKSISQLKDQQDVFCFR
        .::: .  :.  .  : . ..:.:..:.. ...  .: .:. .::. .:.:. :  :  
NP_644 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT
        120       130       140       150       160       170      

        180       190       200       210       220         230    
pF1KB3 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK
        . . .  .      : .:: .:..    ::..::::.     ::. .: : .  :.  .
NP_644 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE
        180       190       200       210       220        230     

          240       250       260       270       280       290    
pF1KB3 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT
       : ::: .::.::: .: .  :.::..:::  :. : ..:: ::.:. :    .:. ::.:
NP_644 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT
         240       250       260       270       280       290     

          300       310       320       330       340       350    
pF1KB3 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN
       :. ..   ..  :.:.:.. .:::: :::::  :.:::.:::: .:::. ::::.::: :
NP_644 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN
         300       310       320       330       340       350     

          360          370       380       390       400       410 
pF1KB3 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
        .: :.: .:..  .   ..:::::::: .. :... :.. . .:  .: .: : ::...
NP_644 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA
         360       370       380       390       400       410     

             420       430       440       450       460       470 
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       :.   .:.::: :::::: .:: ..    ::  .:.: .::::.:::..::  .:::.::
NP_644 GTR--TNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW
           420       430       440       450       460       470   

             480       490       500       510       520       530 
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
       .:.:  . .: .:: .:: : :. :. .::::::: . :::: :::.:: .::.: :  .
NP_644 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S
           480       490       500       510       520       530   

             540       550       560       570       580       590 
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
        : :. :. : :..    ..::: :...::::.. ::  ::::: ::::.:. .:: :::
NP_644 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK
            540       550       560       570       580       590  

             600        610        620       630       640         
pF1KB3 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ
         . ::::::::::: ::.:: .:::. :.  .  ...:.::::. :... . .:::.:.
NP_644 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK
            600       610       620       630       640       650  

     650       660       670             680         690       700 
pF1KB3 LLTEENIPENPLRFLYPRIPRDEAFGCYYQ------EKVNLQERRK--YLKHRLIVVSNR
       ... ::::::::..::: : .:.::: ::.      : ..:.  .   :.: .:: ::  
NP_644 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV
            660       670       680       690       700       710  

             710       720       730       740       750       760 
pF1KB3 QVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEP

>>XP_006712781 (OMIM: 600555,613796,614162,614892) PREDI  (750 aa)
 initn: 1423 init1: 512 opt: 1849  Z-score: 1675.0  bits: 320.8 E(85289): 1.5e-86
Smith-Waterman score: 1867; 43.4% identity (71.2% similar) in 737 aa overlap (1-717:1-729)

               10        20        30        40        50        60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
       :.::  ::.::: : .:.::::. :. :..:::::: :.: :.:..::  .: : ::. :
XP_006 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF
               10        20         30        40          50       

               70        80        90        100       110         
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL
         .:.::. . .: : . ...:::::.::  :..:  :..:: :.. .:.. : ::..::
XP_006 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL
        60        70         80        90       100       110      

     120       130       140       150          160       170      
pF1KB3 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR--AM-MEKLVKSISQLKDQQDVFCFR
        .::: .  :.  .  : . ..:.:..:.. ...  .: .:. .::. .:.:. :  :  
XP_006 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT
        120       130       140       150       160       170      

        180       190       200       210       220         230    
pF1KB3 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK
        . . .  .      : .:: .:..    ::..::::.     ::. .: : .  :.  .
XP_006 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE
        180       190       200       210       220        230     

          240       250       260       270       280       290    
pF1KB3 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT
       : ::: .::.::: .: .  :.::..:::  :. : ..:: ::.:. :    .:. ::.:
XP_006 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT
         240       250       260       270       280       290     

          300       310       320       330       340       350    
pF1KB3 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN
       :. ..   ..  :.:.:.. .:::: :::::  :.:::.:::: .:::. ::::.::: :
XP_006 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN
         300       310       320       330       340       350     

          360          370       380       390       400       410 
pF1KB3 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
        .: :.: .:..  .   ..:::::::: .. :... :.. . .:  .: .: : ::...
XP_006 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA
         360       370       380       390       400       410     

             420       430       440       450       460       470 
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
       :.   .:.::: :::::: .:: ..    ::  .:.: .::::.:::..::  .:::.::
XP_006 GT--RTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW
           420       430       440       450       460       470   

             480       490       500       510       520       530 
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
       .:.:  . .: .:: .:: : :. :. .::::::: . :::: :::.:: .::.: :  .
XP_006 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S
           480       490       500       510       520       530   

             540       550       560       570       580       590 
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
        : :. :. : :..    ..::: :...::::.. ::  ::::: ::::.:. .:: :::
XP_006 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK
            540       550       560       570       580       590  

             600        610        620       630       640         
pF1KB3 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ
         . ::::::::::: ::.:: .:::. :.  .  ...:.::::. :... . .:::.:.
XP_006 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK
            600       610       620       630       640       650  

     650       660       670             680         690       700 
pF1KB3 LLTEENIPENPLRFLYPRIPRDEAFGCYYQ------EKVNLQERRK--YLKHRLIVVSNR
       ... ::::::::..::: : .:.::: ::.      : ..:.  .   :.: .:: ::. 
XP_006 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV
            660       670       680       690       700       710  

             710        720       730       740       750       760
pF1KB3 QVDELQQPLELKP-EPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLE
       . ..::   .: :  ::                                           
XP_006 HPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV                      
            720       730       740       750                      




851 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:42:49 2016 done: Thu Nov  3 13:42:51 2016
 Total Scan time: 14.140 Total Display time:  0.250

Function used was FASTA [36.3.4 Apr, 2011]
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